Movement disorders in Latin America.

abstract：:Cerebrotendinous xanthomatosis (CTX) is an inborn error of cholesterol and bile acid metabolism, leading to neuropsychiatric and systemic manifestations. Movement disorders have rarely been reported in CTX, while a detailed appreciation of the full phenotypic spectrum is required in order to prevent underdiagnosis of ...

journal_title：Parkinsonism & related disorders

authors： Stelten BML,van de Warrenburg BPC,Wevers RA,Verrips A

更新日期：2019-01-01 00:00:00

abstract：:The pedunculopontine nucleus (PPN) is a brainstem locomotive center that also processes sensory and behavioral information. Through its connections with basal ganglia structures and the spinal cord, the PPN may play a role in axial motor symptoms in Parkinson's disease (PD). We review the anatomical features of the PP...

journal_title：Parkinsonism & related disorders

authors： Hamani C,Stone S,Laxton A,Lozano AM

更新日期：2007-01-01 00:00:00

abstract：INTRODUCTION:for a proportion of patients with functional motor symptoms (FMS), specific physiotherapy has recently emerged as a promising treatment. Aim of the present study was to assess in a sample of patients with FMS the efficacy of a physical therapy-based telemedicine programme on the motor symptoms themselves a...

journal_title：Parkinsonism & related disorders

authors： Demartini B,Bombieri F,Goeta D,Gambini O,Ricciardi L,Tinazzi M

更新日期：2020-07-01 00:00:00

abstract：INTRODUCTION:Cognitive impairment can occur in the early phase of Parkinson's disease and increases the risk of developing dementia. Cognitive deficits were shown to be associated with functional alterations in the dorsolateral prefrontal cortex (DLPFC) and caudate nucleus. Two previous transcranial magnetic stimulatio...

journal_title：Parkinsonism & related disorders

authors： Trung J,Hanganu A,Jobert S,Degroot C,Mejia-Constain B,Kibreab M,Bruneau MA,Lafontaine AL,Strafella A,Monchi O

更新日期：2019-09-01 00:00:00

abstract：:The 'hung-up' knee jerk (HUKJ) is a specific, although rarely appreciated, clinical sign of Huntington's Disease. A HUKJ was present in 11 of 31 consecutive patients with Huntington's Disease seen in our practice. The clinical characteristics of these patients are described and an EMG recording of the HUKJ is presente...

journal_title：Parkinsonism & related disorders

authors： Brannan T

更新日期：2003-06-01 00:00:00

abstract：INTRODUCTION:The sonographic appearance of the substantia nigra is abnormally bright and enlarged (hyperechogenic) in young adults with a history of illicit stimulant use. The abnormality is a risk factor for Parkinson's disease. The aim of the current study was to identify the type of illicit stimulant drug associated...

journal_title：Parkinsonism & related disorders

authors： Todd G,Pearson-Dennett V,Wilcox RA,Chau MT,Thoirs K,Thewlis D,Vogel AP,White JM

更新日期：2016-04-01 00:00:00

abstract：:A confluence of variables in Parkinson's disease results in Parkinson's informal caregivers facing tremendous challenges. Factors include: motor and non-motor symptoms, staging, rate of progression and increased life expectancy of people with Parkinson's (PwP) due to effective drug therapy and surgery. Informal caregi...

journal_title：Parkinsonism & related disorders

authors： Dyck C

更新日期：2009-12-01 00:00:00

abstract：:This letter to the editor acknowledges the contribution of Akbar et al. to the field of tardive dyskinesia (TD) and provides important regulatory information about the potential for parkinson-like symptoms in patients with TD who are treated with valbenazine. ...

journal_title：Parkinsonism & related disorders

authors： Shah C

更新日期：2020-02-01 00:00:00

abstract：OBJECTIVES:To determine cortical grey matter (GM) changes and their clinical and biochemical correlates in patients with Wilson's disease using voxel based morphometry (VBM). METHODS:Clinical and imaging data of 10 patients (all male, mean age 16.0 ± 6.3years) with Wilson's Disease were analyzed. T1W volumetric MRI da...

journal_title：Parkinsonism & related disorders

authors： Stezin A,George L,Jhunjhunwala K,Lenka A,Saini J,Netravathi M,Yadav R,Pal PK

更新日期：2016-09-01 00:00:00

abstract：:The opsoclonus-myoclonus syndrome is a pathological condition characterized mainly by involuntary myoclonic movements involving ocular, trunk and limb muscles associated with ataxia and other neurological signs.We describe the case of a 30-year-old woman who developed this syndrome 15days after anti-Rubella vaccinatio...

journal_title：Parkinsonism & related disorders

authors： Lapenna F,Lochi L,de Mari M,Iliceto G,Lamberti P

更新日期：2000-10-01 00:00:00

abstract：OBJECTIVE:Our purpose was to determine whether the use of catechol-O-methyltransferase-inhibitors (ICOMT) can reduce the risk of developing levodopa (LD)-induced neuropathy in Parkinson's disease (PD) patients. METHODS:A multicentre study of 197 PD patients was performed. 144 were exposed to LD for more than three yea...

journal_title：Parkinsonism & related disorders

authors： Cossu G,Ceravolo R,Zibetti M,Arca R,Ricchi V,Paribello A,Murgia D,Merola A,Romagnolo A,Nicoletti V,Palermo G,Mereu A,Lopiano L,Melis M,Abbruzzese G,Bonuccelli U

更新日期：2016-06-01 00:00:00

abstract：INTRODUCTION:Increasing evidence demonstrates the relevant association between Parkinson's disease (PD) and vascular diseases/risk factors, as well as a worse clinico-pathological progression in those patients with vascular comorbidity. The mechanisms underlying this relationship have not been clarified yet, although t...

journal_title：Parkinsonism & related disorders

authors： Imbriani P,D'Angelo V,Platania P,Di Lazzaro G,Scalise S,Salimei C,El Atiallah I,Colona VL,Mercuri NB,Bonsi P,Pisani A,Schirinzi T,Martella G

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND:Visual hallucinations (VH) in Parkinson's disease (PD) are associated with PD dementia and have been related to cognitive impairments in non-demented PD patients. Reports on the specific cognitive domains affected are conflicting. The aim of the present study was to investigate the presence of specific cogni...

journal_title：Parkinsonism & related disorders

authors： Hepp DH,da Hora CC,Koene T,Uitdehaag BM,van den Heuvel OA,Klein M,van de Berg WD,Berendse HW,Foncke EM

更新日期：2013-09-01 00:00:00

abstract：BACKGROUND:Deep brain stimulation surgery (DBS) for movement disorders has become commonplace and patients are beginning to present to specialized centers for second opinions. We aimed to uncover reasons for referral by analyzing a large single center cohort of DBS patients referred for management. METHODS:Data were c...

journal_title：Parkinsonism & related disorders

authors： Kluger BM,Foote KD,Jacobson CE,Okun MS

更新日期：2011-05-01 00:00:00

abstract：OBJECTIVE:Melanopsin may be involved in the pathophysiology of photophobia in idiopathic isolated blepharospasm. We assessed the efficacy of blocking wavelengths of melanopsin absorption to reduce blinking in blepharospasm as a possible surrogate for photophobia. METHODS:Twenty-one participants (11 blepharospasm and 1...

journal_title：Parkinsonism & related disorders

authors： Wu Y,Cho HJ,Panyakaew P,Savant CS,Wu T,Dang N,Hallett M

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND:Non-motor complications of Parkinson's disease (PD), specifically cognitive impairment, sleep disturbances, and fatigue, are recognized as important contributors to poor patient outcomes and quality of life. How sleep problems and fatigue interrelate and impact cognitive function, however, has not systematic...

journal_title：Parkinsonism & related disorders

authors： Goldman JG,Stebbins GT,Leung V,Tilley BC,Goetz CG

更新日期：2014-11-01 00:00:00

abstract：BACKGROUND:Given the heterogeneity of mild cognitive deficits in non-demented Parkinson's disease (PD), sensitive and anatomically specific behavioural measures are crucial when evaluating cognition in this patient group. Inhibitory dysfunction is one such deficit increasingly being recognised in non-demented PD; howev...

journal_title：Parkinsonism & related disorders

authors： O'Callaghan C,Naismith SL,Shine JM,Bertoux M,Lewis SJ,Hornberger M

更新日期：2013-09-01 00:00:00

abstract：INTRODUCTION:There is a dearth of studies of spinocerebellar ataxias (SCAs) and diffusion tensor magnetic resonance imaging (DTI). OBJECTIVE:To analyze changes observed in DTI parameters and correlate these to clinical findings in SCA3 and SCA10 patients. METHODS:SCA3 (n = 19) and SCA10 (n = 18) patients were compare...

journal_title：Parkinsonism & related disorders

authors： Meira AT,Arruda WO,Ono SE,Franklin GL,de Carvalho Neto A,Raskin S,Ashizawa T,Camargo CHF,Teive HAG

更新日期：2020-09-01 00:00:00

abstract：OBJECTIVE:To determine the nationwide prevalence of primary dystonia, ataxia and hereditary spastic paraplegia (HSP) in Sweden. METHODS:We extracted data on all patients who were registered in The National Patient Register (NPR) in Sweden (population 9.64 million) at least twice during five consecutive years with a di...

journal_title：Parkinsonism & related disorders

authors： Hellberg C,Alinder E,Jaraj D,Puschmann A

更新日期：2019-12-01 00:00:00

abstract：:The mild cognitive impairment (MCI) concept was developed to identify the earliest stages of cognitive impairment. MCI and, more specifically, amnestic MCI were initially proposed as transitional states that ultimately progress to full blown Alzheimer's disease (AD). However, MCI subjects do not uniformly progress to ...

journal_title：Parkinsonism & related disorders

authors： Korczyn AD

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Parkinson's disease is characterized by pathological α-synuclein accumulation and cell death, which has been hypothesized to originate in peripheral nerve terminals and subsequently spread via autonomic nerves. Supporting this, most Parkinson's disease patients experience autonomic non-motor symptoms such as...

journal_title：Parkinsonism & related disorders

authors： Knudsen K,Fedorova TD,Hansen AK,Sommerauer M,Haase AM,Svendsen KB,Otto M,Østergaard K,Krogh K,Borghammer P

更新日期：2019-01-01 00:00:00

abstract：:Freezing of gait (FOG) is a common phenomenon in Parkinson's disease (PD) affecting over half of those in the advanced stages of the disease and often does not respond to standard drug therapies. This article proposes a possible mechanism by which this disorder of movement comes about. Co-ordinated neural activities a...

journal_title：Parkinsonism & related disorders

authors： Lewis SJ,Barker RA

更新日期：2009-06-01 00:00:00

abstract：:Deficiency in skilled motor activity is primarily attributed to the loss of dopaminergic neurons in the pars compacta of substantia nigra (SNc), which can be detected by performance of the rotarod test. Previous reports have demonstrated impaired skilled motor behavior in rats during the pre-motor stage of Parkinson's...

journal_title：Parkinsonism & related disorders

authors： Gambhir H,Mathur R,Behari M

更新日期：2011-07-01 00:00:00

abstract：OBJECTIVE:To evaluate the efficacy of solifenacin succinate in Parkinson's disease (PD) patients suffering from overactive bladder (OAB). BACKGROUND:Urinary dysfunction is a commonly encountered non-motor feature in PD that significantly impacts patient quality of life. DESIGN/METHODS:This was a double-blind, randomi...

journal_title：Parkinsonism & related disorders

authors： Zesiewicz TA,Evatt M,Vaughan CP,Jahan I,Singer C,Ordorica R,Salemi JL,Shaw JD,Sullivan KL,Non-Motor Working Group of the Parkinson Study Group (PSG).

更新日期：2015-05-01 00:00:00

abstract：:Levodopa (LD) is the most effective drug for symptomatic control of Parkinsonism (PS). As prolonged LD therapy leads to response failure; is associated with adverse effects; may accelerate disease process, and its impact on life expectancy is controversial, delaying LD use has been recommended. We studied 934 PS cases...

journal_title：Parkinsonism & related disorders

authors： Rajput AH,Uitti RJ,Rajput AH,Offord KP

更新日期：1997-11-01 00:00:00

abstract：OBJECTIVE:To describe the long-term outcome in 50 consecutive advanced Parkinson's disease (PD) patients treated with subthalamic nucleus deep brain stimulation (STN-DBS). METHOD:Assessments were carried out at baseline, 6 months, 2 years, and 5 years postoperatively. RESULTS:Compared to baseline scores without medic...

journal_title：Parkinsonism & related disorders

authors： Wider C,Pollo C,Bloch J,Burkhard PR,Vingerhoets FJ

更新日期：2008-01-01 00:00:00

abstract：INTRODUCTION:The DUALITY trial recently showed that both integrated and consecutive dual-task training improve dual-task gait velocity, without increasing fall risks in patients with Parkinson's disease (PD). Gait velocity was the primary outcome; not reported, however, were important gait measures related to the risk ...

journal_title：Parkinsonism & related disorders

authors： Geroin C,Nonnekes J,de Vries NM,Strouwen C,Smania N,Tinazzi M,Nieuwboer A,Bloem BR

更新日期：2018-10-01 00:00:00

abstract：INTRODUCTION:Tremor is frequently associated with dystonia, but its pathophysiology is still unclear. Dysfunctions of cerebellar circuits are known to play a role in the pathophysiology of action-induced tremors, and cerebellar impairment has frequently been associated to dystonia. However, a link between dystonic trem...

journal_title：Parkinsonism & related disorders

authors： Antelmi E,Di Stasio F,Rocchi L,Erro R,Liguori R,Ganos C,Brugger F,Teo J,Berardelli A,Rothwell J,Bhatia KP

更新日期：2016-10-01 00:00:00

abstract：:Dystonia is an incurable movement disorder which can cause not only physical but also mental problems, leading to impaired health-related quality of life (HRQoL). For patients with dystonia refractory to medical treatment, deep brain stimulation (DBS) is a well-established surgical treatment. The objective of this sys...

journal_title：Parkinsonism & related disorders

authors： Tsuboi T,Wong JK,Okun MS,Ramirez-Zamora A

更新日期：2020-01-01 00:00:00

abstract：INTRODUCTION:Although the hallmark feature of essential tremor (ET) is tremor, there is growing appreciation that cognitive impairment also occurs, including increased prevalence of mild cognitive impairment (MCI) and increased prevalence and incidence of dementia. With emerging knowledge of ET-cognitive impairment, co...

journal_title：Parkinsonism & related disorders

authors： Louis ED,Joyce JL,Cosentino S

更新日期：2019-06-01 00:00:00