Tissue distribution and plasma clearance of heparin-binding EGF-like growth factor (HB-EGF) in adult and newborn rats.

abstract：:Urotensin II (UII), which was originally isolated from the teleost urophysis, was identified as an endogenous ligand for orphan G protein-coupled receptor 14 (GPR14). The structure of mammalian UII was confirmed by isolation from spinal cord in porcine, or was easily predicted from the sequence of prepro-UII in human....

journal_title：Peptides

authors： Sugo T,Mori M

更新日期：2008-05-01 00:00:00

abstract：:In this work, we characterized the active site in the alpha-melanotropin hormone (alpha-MSH) sequence responsible for the enhancement of cAMP production in incubated striatal slices by using different alpha-MSH fragments. We also analyzed the effects of the co-incubation of the SCH23390, a dopaminergic D(1) antagonist...

journal_title：Peptides

authors： Cecilia Cremer M,Silvina Sanchez M,Ester Celis M

更新日期：2000-06-01 00:00:00

abstract：:As a class of peptides with 10 cysteine residues (-C-CC-C-CC-C-C-C-C-), D-superfamily conotoxins (D-conotoxins) can specifically act on nicotinic acetylcholine receptors (nAChRs). According to the conserved signal peptides of D-conotoxins, seven D-conotoxin precursor sequences with a previously undescribed Cys arrange...

journal_title：Peptides

authors： Lu J,Zhang K,Wang S,Sun T,Yu S,Dai Q,Liu Z

更新日期：2017-08-01 00:00:00

abstract：:Age-related changes in NPY-driven angiogenesis were investigated using Matrigel and aortic sprouting assays in young (2 months.) and aged (18 months.) mice. In both assays, NPY-induced vessel growth decreased significantly with age. In parallel, aged mice showed reduced expression (RT-PCR) of Y2 receptors and the NPY ...

journal_title：Peptides

authors： Kitlinska J,Lee EW,Movafagh S,Pons J,Zukowska Z

更新日期：2002-01-01 00:00:00

abstract：:The distribution of somatostatin (SRIF) was examined in normal human forebrain, using thick vibratome cut sections. The unlabeled antibody enzyme method of immunocytochemistry revealed a widespread distribution of SRIF immunoreactive neurons and fibers throughout the septum, diencephalon and corpus striatum. Within th...

journal_title：Peptides

authors： Bennett-Clarke CA,Joseph SA

更新日期：1986-09-01 00:00:00

abstract：:The distribution of FMRFamide-like-immunoreactive peptides was investigated in the brain and pituitary of the elasmobranch fish Scyliorhinus canicula using the indirect immunofluorescence technique. FMRFamide-immunoreactive cells and fibers were mainly observed in the telencephalon and the diencephalon, while other br...

journal_title：Peptides

authors： Vallarino M,Salsotto-Cattaneo MT,Feuilloley M,Vaudry H

更新日期：1991-11-01 00:00:00

abstract：:Circulating urotensin II (UII) concentrations and the tissue expression of its cognate receptor (UT) are elevated in patients with cardiovascular disease (CVD). The functional significance of elevated plasma UII levels in CVD is unclear. Urotensin-related peptide (URP) is a paralog of UII in that it contains the six a...

journal_title：Peptides

authors： Prosser HC,Forster ME,Richards AM,Pemberton CJ

更新日期：2008-05-01 00:00:00

abstract：:A novel protein expressed by entero-endocrine cells of the mouse stomach was named prepromotilin Related Peptide (ppMTLRP) since it shares sequence similarities with the prepromotilin (Tomasetto et al.). The mouse ppMTLRP was found identical to the rat precursor of ghrelin (ppghrelin), an endogenous ligand specific fo...

journal_title：Peptides

authors： Tomasetto C,Wendling C,Rio MC,Poitras P

更新日期：2001-12-01 00:00:00

abstract：:Hypocretin-1 (hcrt-1) and hypocretin-2 (hcrt-2) are two recently discovered hypothalamic neuropeptides. In the present study, using double immunofluorescent techniques, the co-localization of hcrt-1 and hcrt-2 was examined in neuronal soma and fibers/terminals located, respectively, in the cat hypothalamus and brainst...

journal_title：Peptides

authors： Zhang JH,Sampogna S,Morales FR,Chase MH

更新日期：2002-08-01 00:00:00

abstract：:To determine whether centrally released vasopressin influences thirst, observations of osmotic thirst threshold, osmotic load excretion and postloading restitution of plasma osmolality were made in dogs in control experiments and during infusion of AVP antagonists into the third ventricle. Significant elevation of osm...

journal_title：Peptides

authors： Szczepanska-Sadowska E,Sobocinska J,Kozłowski S

更新日期：1987-11-01 00:00:00

abstract：:Brazilian freshwater stingrays, Potamotrygon gr. orbigyni, are relatively common in the middle-western regions of Brazil, where they are considered an important public health threat. In order to identify some of their naturally occurring toxin peptides available in very low amounts, we combine analytical protocols suc...

journal_title：Peptides

authors： Conceição K,Santos JM,Bruni FM,Klitzke CF,Marques EE,Borges MH,Melo RL,Fernandez JH,Lopes-Ferreira M

更新日期：2009-12-01 00:00:00

abstract：:To identify male-specific genes that could be involved in male development, we screened a subtracted male reproductive tract library and isolated a novel gene named Mar-Mrr (M. rosenbergii male reproduction-related gene). The Mar-Mrr cDNA sequence consists of 683 nucleotides with a 333 nucleotide open reading frame, e...

journal_title：Peptides

authors： Cao JX,Yin GL,Yang WJ

更新日期：2006-04-01 00:00:00

abstract：:We examined the effect of adjuvant arthritis on the content of immunoreactive calcitonin gene-related peptide (iCGRP) in the dorsal root ganglia at L4-L6 levels and the spinal cord at a lumbar level in rats. Arthritis was induced by inoculating adjuvant into both hind-paws twice at a 10 day interval. In the arthritic ...

journal_title：Peptides

authors： Kuraishi Y,Nanayama T,Ohno H,Fujii N,Otaka A,Yajima H,Satoh M

更新日期：1989-03-01 00:00:00

abstract：:We demonstrated previously that hippocampal dentate gyrus neurons were sensitive to angiotensin II (AII) and recently discovered that AII applied directly to the dentate gyrus inhibited granule cell long-term potentiation induction and that the inhibition is mediated by the AT1 receptor and can be blocked by losartan,...

journal_title：Peptides

authors： Lee EH,Ma YL,Wayner MJ,Armstrong DL

更新日期：1995-01-01 00:00:00

abstract：:The neuroendocrine and behavioral effects of Tyr-D-Ala-Gly-Phe-D-Nle-Arg-Phe (DADN), a more stable derivative of the endogenous opiate Met-enkephalin related peptide Met(5)-enkephalin-Arg(6)-Phe(7) were investigated in mice. The behavioral experiments consisted of monitoring the horizontal (square crossing) and vertic...

journal_title：Peptides

authors： Csabafi K,Jászberényi M,Bagosi Z,Tóth G,Wollemann M,Telegdy G

更新日期：2011-08-01 00:00:00

abstract：:Trefoil factors family 2 (TFF2), also known as spasmolytic polypeptide, is primarily expressed in the mucus neck cells of gastrointestinal tracts. It has been proposed that TFF2 plays an important physiological role in protection, repair, and healing of gastrointestinal mucosa. To investigate the cis-acting regulatory...

journal_title：Peptides

authors： Chi AL,Lim S,Wang TC

更新日期：2004-05-01 00:00:00

abstract：:Peptic digestion of bovine hemoglobin at low degree of hydrolysis yields an intermediate peptide fraction exhibiting antibacterial activity against Micrococcus luteus A270, Listeria innocua, Escherichia coli and Salmonella enteritidis after separation by reversed-phase HPLC. From this fraction a pure peptide was isola...

journal_title：Peptides

authors： Daoud R,Dubois V,Bors-Dodita L,Nedjar-Arroume N,Krier F,Chihib NE,Mary P,Kouach M,Briand G,Guillochon D

更新日期：2005-05-01 00:00:00

abstract：:An antiserum directed against the COOH-terminal region of neuropeptide K-(1-24)-peptide that shows only 0.5% reactivity with neuropeptide K has been used in radioimmunoassay to study the posttranslation processing of human beta-preprotachykinin. A primary midgut carcinoid tumor contained high concentration of substanc...

journal_title：Peptides

authors： Conlon JM,Deacon CF,Grimelius L,Cedermark B,Murphy RF,Thim L,Creutzfeldt W

更新日期：1988-07-01 00:00:00

abstract：BACKGROUND:Since short bowel syndrome (SBS) patients face life-threatening conditions, the development of therapeutic strategies to induce intestinal adaptation has been investigated. Ghrelin, a ligand of growth hormone (GH) secretagogue-receptor that stimulates the release of GH and insulin like growth factor-1 (IGF-1...

journal_title：Peptides

authors： Onishi S,Kaji T,Yamada W,Nakame K,Machigashira S,Kawano M,Yano K,Harumatsu T,Yamada K,Masuya R,Kawano T,Mukai M,Hamada T,Souda M,Yoshioka T,Tanimoto A,Ieiri S

更新日期：2018-08-01 00:00:00

abstract：:Mate attraction in Aplysia involves the long-distance water-borne protein pheromones attractin, enticin, and temptin which are released during egg-laying. Other water-borne pheromones are predicted to act in concert with attractin, enticin, and temptin, but their identities were unknown. We recently identified a highl...

journal_title：Peptides

authors： Cummins SF,Nichols AE,Warso CJ,Nagle GT

更新日期：2005-03-01 00:00:00

abstract：:We examined the expressions of the prepro-orexin gene in the lateral hypothalamic area (LHA), the genes of the neuropeptide Y (NPY) and proopiomelanocortin (POMC) in the arcuate nucleus (ARC), the orexin type 1 receptor (OX1R) gene in the ventromedial hypothalamic nucleus (VMH) and the orexin type 2 receptor (OX2R) ge...

journal_title：Peptides

authors： Yamamoto Y,Ueta Y,Yamashita H,Asayama K,Shirahata A

更新日期：2002-09-01 00:00:00

abstract：:Intravenous (IV) infusions of neurotensin (NT) in anesthetized guinea pigs elicited dose-dependent pressor effects and tachycardia. Both effects were significantly reduced or abolished in guinea pigs given a chronic treatment with the neurotoxin capsaicin. In guinea pig isolated atria NT evoked a positive inotropic an...

journal_title：Peptides

authors： Bachelard H,St-Pierre S,Rioux F

更新日期：1987-11-01 00:00:00

abstract：:The intracranial injection of an opioid antagonist (naloxone) caused aggregation of xanthophores in goldfish scales. This aggregating effect produced by naloxone was inhibited by an injection of methionine-enkephalin (M-ENK). M-ENK, when injected together with melatonin which normally produces aggregation of xanthopho...

journal_title：Peptides

authors： Satake N

更新日期：1980-04-01 00:00:00

abstract：:CRF system, structural conservation, has an association with feeding regulation in mammals. However, mammals and fish have different physiological mechanisms, the potential role of CRF system for feeding regulation in teleost fish are most unknown. To better explore possible feeding mechanisms of CRF system in Acipens...

journal_title：Peptides

authors： Qi J,Xu S,Wang M,Chen H,Tang N,Wang B,Li Y,Zhang X,Chen D,Zhou B,Zhao L,Wang Y,Li Z

更新日期：2020-06-01 00:00:00

abstract：:The goal of our study was to explore the effect of social isolation stress of varying durations on the plasma oxytocin (OT), messenger ribonucleic acid (mRNA) for oxytocin receptor (OTR), plasma arginine vasopressin (AVP) and mRNA for V1a receptor of AVP (V1aR) expression in the hypothalamus and heart of socially mono...

journal_title：Peptides

authors： Pournajafi-Nazarloo H,Kenkel W,Mohsenpour SR,Sanzenbacher L,Saadat H,Partoo L,Yee J,Azizi F,Carter CS

更新日期：2013-05-01 00:00:00

abstract：:The decapeptide from the frog Hyla caerulea, caerulein (caerulein diethylammonium hydrate, ceruletide, CER) is chemically closely related to the C-terminal octapeptide of cholecystokinin (CCK-8). Like CCK-8, CER and some of its analogues produce many behavioural effects in mammals: inhibition of intake of food and wat...

journal_title：Peptides

authors： Zetler G

更新日期：1985-01-01 00:00:00

abstract：:The acute behavioral effects of some neurohypophyseal hormones after intracerebroventricular injection in mice were examined. The effects, consisting mainly of a dose-dependent stimulation of certain behaviors, were demonstrated in three different behavioral tests. The type of the induced behaviors was dependent on th...

journal_title：Peptides

authors： Meisenberg G

更新日期：1981-04-01 00:00:00

abstract：:Antimicrobial peptides produced by multicellular organisms protect against pathogenic microorganisms, whereas such peptides produced by bacteria provide an ecological advantage over competitors. Certain antimicrobial peptides of metazoan origin are also toxic to eukaryotic cells, with preference for a variety of cance...

journal_title：Peptides

authors： Sand SL,Oppegård C,Ohara S,Iijima T,Naderi S,Blomhoff HK,Nissen-Meyer J,Sand O

更新日期：2010-07-01 00:00:00

abstract：:Synthetic peptides containing a phosphorylation site for protein kinase CK2 were used to investigate their binding properties to other peptides/proteins. The aim of this work was to find an efficient procedure to search for these peptide/protein ligands. The goal was successfully achieved through screening of random p...

journal_title：Peptides

authors： Cardellini E,Felici F,Gianfranceschi GL

更新日期：2004-02-01 00:00:00

abstract：:We have previously shown that brief, vena caval infusion of gastrin-releasing peptide1-27 (GRP), delivered shortly (5 min) after the end of the first spontaneous nocturnal meal, significantly prolongs the postprandial intermeal interval (IMI) without affecting the size of the subsequent meal in freely-feeding rats. In...

journal_title：Peptides

authors： Rushing PA,Gibbs J

更新日期：1998-01-01 00:00:00