Metastases to the peripheral nervous system.

abstract：:The aim of this article is to evaluate and assess the impact of various factors on quality of life (QOL) in adult patients with primary brain tumors seen consecutively in routine neurooncology practice. Two hundred and fifty-seven adult patients, after undergoing surgical intervention and histologically proven primary...

journal_title：Journal of neuro-oncology

authors： Budrukkar A,Jalali R,Dutta D,Sarin R,Devlekar R,Parab S,Kakde A

更新日期：2009-12-01 00:00:00

abstract：INTRODUCTION:Intramedullary spinal cord metastases (ISCMs) are rare lesions affecting the spinal cord in patients with disseminated malignancy. Today, due to increased survival, these lesions are more frequently diagnosed. Literature on survival and neurologic outcomes is sparse. Herein, we describe a single institutio...

journal_title：Journal of neuro-oncology

authors： Goyal A,Yolcu Y,Kerezoudis P,Alvi MA,Krauss WE,Bydon M

更新日期：2019-04-01 00:00:00

abstract：:Patients with high grade glioma generally have poor prognoses. Addition of radiosensitizing agents might improve the response to irradiation. The chemotherapeutic agent estramustine sensitizes experimental gliomas to radiation. Gliomas express estramustine binding proteins, and cytotoxic concentrations of estramustine...

journal_title：Journal of neuro-oncology

authors： Landy H,Markoe A,Potter P,Lasalle G,Marini A,Savaraj N,Reis I,Heros D,Wangpaichitr M,Feun L

更新日期：2004-03-01 00:00:00

abstract：:One objection to using cell cultures for studying the proliferation of tumors is the potential for phenotypic changes that may occur in vitro. Here, we compared the antigen pattern expression of cultured meningioma cells with that of the primary tumor. Cell cultures established from 9 intracranial meningiomas and depa...

journal_title：Journal of neuro-oncology

authors： Pallini R,Casalbore P,Mercanti D,Maggiano N,Larocca LM

更新日期：2000-08-01 00:00:00

abstract：:In a retrospective analysis based on a malignant glioma databank, we describe effects of age, sex and diagnosis upon survival in patients with malignant cerebral glioma with a pre-treatment Karnofsky-index of 60 or more. All patients had been treated with 55-60Gy radiotherapy and nitrosurea-based adjuvant chemotherapy...

journal_title：Journal of neuro-oncology

authors： Diete S,Treuheit T,Dietzmann K,Schmidt U,Wallesch CW

更新日期：2001-05-01 00:00:00

abstract：:Papillary meningioma is a rare subtype of meningioma that often behaves aggressively. In order to characterize factors that may influence this behavior, we chose to compare MIB-1 labeling index (LI) and telomerase RNA localization (hTR) in papillary meningiomas, meningiomas, and atypical meningiomas. LI is now often u...

journal_title：Journal of neuro-oncology

authors： Rushing EJ,Colvin SM,Gazdar A,Miura N,White CL 3rd,Coimbra C,Burns DK

更新日期：1999-01-01 00:00:00

abstract：:Fibroblast growth factor-2 (FGF-2) is involved as an autocrine growth factor in the autonomous proliferation of glioma cells. To develop a new strategy for treating patients with glioma, we studied the effect on human glioma cells of a 16-mer oligopeptide with conformational similarity to the putative receptor-binding...

journal_title：Journal of neuro-oncology

authors： Kono K,Ueba T,Takahashi JA,Murai N,Hashimoto N,Myoumoto A,Itoh N,Fukumoto M

更新日期：2003-06-01 00:00:00

abstract：:The records of thirty-four patients with meningeal carcinomatosis treated at our hospital between 1984 and 1990 were reviewed. The sources, histologies, metastatic lesions outside the central nervous system, the history of the treatment of primary lesions and intraparenchymal of metastatic brain tumors and the period ...

journal_title：Journal of neuro-oncology

authors： Nakagawa H,Murasawa A,Kubo S,Nakajima S,Nakajima Y,Izumoto S,Hayakawa T

更新日期：1992-05-01 00:00:00

abstract：:Pilocytic astrocytomas are rare intracranial gliomas that are typically treated with surgical extirpation. Our aim was to report the radiologic and clinical outcomes of patients treated with stereotactic radiosurgery (SRS) for pilocytic astrocytoma in the primary and salvage setting. Patients with pilocytic astrocytom...

journal_title：Journal of neuro-oncology

authors： Trifiletti DM,Peach MS,Xu Z,Kersh R,Showalter TN,Sheehan JP

更新日期：2017-09-01 00:00:00

abstract：:Intramedullary spinal cord metastases of solid neoplasms are associated with poor long-term survival. As the characteristics of secondary intramedullary spinal cord non-Hodgkin's lymphoma (NHL) are not well understood, we sought to describe its clinical features and outcome. We retrospectively reviewed the Mayo Clinic...

journal_title：Journal of neuro-oncology

authors： Flanagan EP,O'Neill BP,Habermann TM,Porter AB,Keegan BM

更新日期：2012-05-01 00:00:00

abstract：PURPOSE:The poor results from treatment of high grade glioma prompted us to explore new protocols involving concurrent radio-chemotherapy. Our primary objective was to evaluate the feasibility of very early postoperative chemotherapy with BCNU, concurrent radio-chemotherapy with carboplatin and teniposide, and post-rad...

journal_title：Journal of neuro-oncology

authors： Brandes AA,Rigon A,Zampieri P,Scelzi E,Amistà P,Berti F,Rotilio A,Gardiman M,Fiorentino MV

更新日期：1996-12-01 00:00:00

abstract：:While surgery is proned in low-grade glioma (LGG), the invasion of functional areas frequently prevents a complete resection. We report the first case of a patient operated on for a left frontal LGG, diagnosed because of seizures, with partial resection due to an invasion of the controlateral hemisphere. Chemotherapy ...

journal_title：Journal of neuro-oncology

authors： Duffau H,Taillandier L,Capelle L

更新日期：2006-11-01 00:00:00

abstract：:Thymidine analogs (TAs) are synthetic nucleosides that incorporate into newly synthesized DNA. Halogenated pyrimidines (HPs), such as bromodeoxyuridine (BrdU), are a class of TAs that can be detected with antibodies and are commonly used for birthdating individual cells and for assessing the proliferative index of cel...

journal_title：Journal of neuro-oncology

authors： Ross HH,Rahman M,Levkoff LH,Millette S,Martin-Carreras T,Dunbar EM,Reynolds BA,Laywell ED

更新日期：2011-12-01 00:00:00

abstract：:A phase II trial of Homoharringtonine (HHT) was performed in 15 patients with recurrent or progressive malignant glioma. The drug was administered at a initial dose of 4 mg/m2/day by continuous 5 day intravenous infusion (3 mg/m2/day x 5 days for heavily pretreated patients). Courses were repeated every 3-4 weeks upon...

journal_title：Journal of neuro-oncology

authors： Feun LG,Savaraj N,Landy H,Levin H,Lampidis T

更新日期：1990-10-01 00:00:00

abstract：:The effectiveness of temozolomide (TMZ) dosing schemes and the "rechallenge" of recurrent glioblastoma (GBM) with TMZ are controversial. We therefore compared the efficacy of different TMZ dosing schemes against GBM cancer stem cell (CSC) lines in vitro. In O(6)-methyl-guanidine-methyl-transferase (MGMT)-negative CSC ...

journal_title：Journal of neuro-oncology

authors： Beier D,Schriefer B,Brawanski K,Hau P,Weis J,Schulz JB,Beier CP

更新日期：2012-08-01 00:00:00

abstract：:In 2007 the WHO Classification of Tumours of the Central Nervous System introduced the entity "glioblastoma with oligodendroglioma component" (GBM/OLIGO). This entity accounts for approximately one in every ten new glioblastomas (GBM). In practice, those mixed gliomas with necrosis which were previously diagnosed as a...

journal_title：Journal of neuro-oncology

authors： Marucci G

更新日期：2011-09-01 00:00:00

abstract：PURPOSE:Recent advances in targeted therapy have prolonged overall survival (OS) for patients with lung cancer. The impact of epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKI) on brain metastases (BM) treated with stereotactic radiosurgery (SRS) has not, however, been fully elucidated. We investiga...

journal_title：Journal of neuro-oncology

authors： Yomo S,Serizawa T,Yamamoto M,Higuchi Y,Sato Y,Shuto T,Akabane A,Jokura H,Kawagishi J,Aoyama H

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND:Tumor treating fields (TTFields) are anti-mitotic, non-invasive loco-regional cancer therapy comprising low intensity, intermediate frequency alternating electric fields. TTFields plus Temozolomide (TTFields/TMZ) extended survival versus TMZ alone in newly diagnosed glioblastoma (GBM) patients in the EF-14 t...

journal_title：Journal of neuro-oncology

authors： Kim CY,Paek SH,Nam DH,Chang JH,Hong YK,Kim JH,Kim OL,Kim SH

更新日期：2020-02-01 00:00:00

abstract：:The relationship between coagulation cascade activation and glioma cell proliferation was examined. The human glioma cell lines T98G, TM-1 and normal human astrocyte cell strain (NHA) were examined. Using anti-tissue factor (TF) antibody, immunocytochemical detection of TF antigen was obtained in both cell lines and c...

journal_title：Journal of neuro-oncology

authors： Ogiichi T,Hirashima Y,Nakamura S,Endo S,Kurimoto M,Takaku A

更新日期：2000-01-01 00:00:00

abstract：:The treatment of visual pathway gliomas is controversial. The many retrospective studies reporting outcome data for patients with chiasmatic/hypothalamic gliomas are difficult to interpret for several reasons. First the natural history of these tumors is erratic with some reports suggesting that most visual pathway gl...

journal_title：Journal of neuro-oncology

authors： Garvey M,Packer RJ

更新日期：1996-05-01 00:00:00

abstract：:A historically controlled phase II study was undertaken to investigate the efficacy and toxicity of a postoperative treatment consisting of high-dose continuous tamoxifen, carboplatin and radiotherapy in patients with newly diagnosed glioblastoma. Between 1995 and 1998, 50 patients with newly diagnosed glioblastomas u...

journal_title：Journal of neuro-oncology

authors： Puchner MJ,Herrmann HD,Berger J,Cristante L

更新日期：2000-09-01 00:00:00

abstract：INTRODUCTION:While hypofractionated stereotactic radiotherapy (HFSRT) is being increasingly used for treating brain metastases, clinical data concerning the incidence and risk factors of its main side-effect, namely radiation necrosis (RN), remain limited. In this context, we assessed risk factors of RN in a single cen...

journal_title：Journal of neuro-oncology

authors： Di Perri D,Tanguy R,Malet C,Robert A,Sunyach MP

更新日期：2020-09-01 00:00:00

abstract：:A prospective study was performed in patients treated with cisplatin to evaluate the occurrence and degree of central, peripheral and autonomic neuropathy and to determine the most accurate method to study this neuropathy. Twelve patients were examined before, during and after treatment. Evaluation included neurologic...

journal_title：Journal of neuro-oncology

authors： Boogerd W,ten Bokkel Huinink WW,Dalesio O,Hoppenbrouwers WJ,van der Sande JJ

更新日期：1990-12-01 00:00:00

abstract：UNLABELLED:The pupose of this study is to assess the long-term outcome and toxicity of fractionated stereotactic radiation therapy (FSRT) and stereotactic radiosurgery (SRS) for 100 vestibular schwannomas treated at a single institution. From 1993 to 2007, 104 patients underwent were treated with radiation therapy for ...

journal_title：Journal of neuro-oncology

authors： Anderson BM,Khuntia D,Bentzen SM,Geye HM,Hayes LL,Kuo JS,Baskaya MK,Badie B,Basavatia A,Pyle GM,Tomé WA,Mehta MP

更新日期：2014-01-01 00:00:00

abstract：:The utility of current response criteria has not been established in anaplastic astrocytoma (AA). We retrospectively reviewed MR images for 20 patients with AA and compared RANO-based approaches to clinician impression described as follow: (1) standard RANO-based criteria met by growth of or development of new enhanci...

journal_title：Journal of neuro-oncology

authors： Kazda T,Hardie JG,Pafundi DH,Kaufmann TJ,Brinkmann DH,Laack NN

更新日期：2015-03-01 00:00:00

abstract：:Anti-VEGF therapy with Bevacizumab (BEV) is widely used in cases of relapsed high-grade glioma (HGG). Arterial hypertension is a known side effect of anti-VEGF therapy. 42 Patients with relapsed HGG were treated with BEV 10 mg/kg on days 1 and 15 of 28-day cycles in addition to treatment with 40 mg TMZ daily until dis...

journal_title：Journal of neuro-oncology

authors： Bumes E,Rzonsa S,Hutterer M,Proescholdt M,Bogdahn U,Riemenschneider MJ,Uhl M,Wendl C,Hau P

更新日期：2016-03-01 00:00:00

abstract：:This paper presents a study of the effects of scanning parameters variability when assessing glioma sizes on MRI. A database of lesions of various shapes and sizes, segmented on 3D-SPGR MRI images, was acquired on 65 patients with low-grade glioma. Simulations of large slice thickness and patient's head rotation were ...

journal_title：Journal of neuro-oncology

authors： Schmitt P,Mandonnet E,Perdreau A,Angelini ED

更新日期：2013-04-01 00:00:00

abstract：:Twenty-nine patients received the cytotoxic radiosensitizing agent lonidamine before, during, and after cranial irradiation for brain metastases. One patient was ineligible (meningioma). In 28 eligible patients, median survival was 29 weeks (range, 2 to > 220 weeks). Nine patients (32%) survived > 1 year and 3 (11%) s...

journal_title：Journal of neuro-oncology

authors： Stewart DJ,Eapen L,Girard A,Verma S,Genest P,Evans WK

更新日期：1993-01-01 00:00:00

abstract：:There are two errors and one omission in the original article. Author Gottardo's correct name is Nicholas G. Gottardo, author Hulleman's correct affiliation is no. 3 (VUMC, Amsterdam), and the Acknowledgements should include the following sentence: "We would like to thank Dr Angel Montero Carcaboso (Hospital Sant Joan...

journal_title：Journal of neuro-oncology

authors： Tsoli M,Shen H,Mayoh C,Franshaw L,Ehteda A,Upton D,Carvalho D,Vinci M,Meel MH,van Vuurden D,Plessier A,Castel D,Drissi R,Farrell M,Cryan J,Crimmins D,Caird J,Pears J,Francis S,Ludlow LEA,Carai A,Mastronuzzi A,

更新日期：2019-01-01 00:00:00

abstract：:Malignant primary spinal cord gliomas (PSCGs) are rare, and the optimal treatment for these lesions remains controversial. We report herein treatment outcomes of six malignant PSCGs managed with temozolomide (TMZ)-based multidisciplinary treatment. TMZ was administered concomitantly with fractionated radiotherapy for ...

journal_title：Journal of neuro-oncology

authors： Kim WH,Yoon SH,Kim CY,Kim KJ,Lee MM,Choe G,Kim IA,Kim JH,Kim YJ,Kim HJ

更新日期：2011-01-01 00:00:00