Abstract:
:Cassia tora fiber supplement consisting of 2 g of soluble fiber extracted from Cassia semen (C. tora L.), 200 mg of alpha-tocopherol, 500 mg of ascorbic acid, and 300 mg of maltodextrin was formulated in a pack, and given to 15 type II diabetic subjects (seven men and eight women 57.1 +/- 2.9 years old) with instructions to take two packs per day for 2 months. Placebo contained maltodextrin only with a little brown caramel color. Lifestyle factors and dietary intakes of the subjects were not altered during the 2-month period. Serum total cholesterol was moderately (P < .1) decreased in the C. tora group compared with the age- and gender-matched placebo group, as was the ratio of apolipoprotein B to apolipoprotein A1 (P < .1). Levels of serum triglycerides and low-density lipoprotein-cholesterol tended to decrease more in the C. tora-supplemented group than in the placebo group. Serum alpha-tocopherol was increased (P < .01) but lipid peroxides were not significantly lower in the C. tora group. Fasting blood glucose, hemoglobin A1c, blood urea nitrogen, creatinine, and activities of serum aspartate aminotransferase and alanine aminotransferase were not changed by the fiber supplement. We concluded that C. tora supplements can help improve serum lipid status in type II diabetic subjects without serious adverse effects.
journal_name
J Med Foodjournal_title
Journal of medicinal foodauthors
Cho SH,Kim TH,Lee NH,Son HS,Cho IJ,Ha TYdoi
10.1089/jmf.2005.8.311subject
Has Abstractpub_date
2005-10-01 00:00:00pages
311-8issue
3eissn
1096-620Xissn
1557-7600journal_volume
8pub_type
临床试验,杂志文章,随机对照试验abstract::Four randomized, blind, placebo-controlled clinical trials were pooled to study the general effects of oral consumption of Lycium barbarum at 120 mL/day, as a standardized juice, GoChi(®) (FreeLife International, Phoenix, AZ, USA). A questionnaire consisting of symptoms graded 0-5 was given to the participants. For ea...
journal_title:Journal of medicinal food
pub_type: 杂志文章,meta分析
doi:10.1089/jmf.2012.0013
更新日期:2012-11-01 00:00:00
abstract::We examined the effects of Rhizoma Dioscoreae Tokoronis extracts (RDTEs) on plasma lipids, body weight, and lipogenic enzymes. Mice were administered a standard chow diet, a 60% high-fat diet, or a high-fat diet with RDTE. Mice that were fed a high-fat diet containing RDTE were found to have lower increases in body an...
journal_title:Journal of medicinal food
pub_type: 杂志文章
doi:10.1089/jmf.2008.1010
更新日期:2009-04-01 00:00:00
abstract::The use of synbiotics as health promoters is still poorly defined, and human intervention studies are scarce. This study was designed to evaluate the effects of a commercialized synbiotic product containing Lactobacillus acidophilus La5, Bifidobacterium animalis ssp. lactis Bb-12, Lactobacillus delbrueckii ssp. bulgar...
journal_title:Journal of medicinal food
pub_type: 杂志文章,随机对照试验
doi:10.1089/jmf.2008.0328
更新日期:2011-01-01 00:00:00
abstract::In Mexico about 4,000 plant species have some medicinal use. The aim of this work was to evaluate the antimicrobial activity of six Mexican medicinal plants against fungi and Gram-positive and Gram-negative bacteria. Methanolic extracts were prepared from the Mexican medicinal plants Amphypteringium adstrigens, Castel...
journal_title:Journal of medicinal food
pub_type: 杂志文章
doi:10.1089/jmf.2008.0205
更新日期:2009-12-01 00:00:00
abstract::The present study examined, for the first time, the in vitro wound healing potential of chitosan green tea polyphenols (CGP) complex based on the activation of transglutaminase (TGM) genes in epidermal morphogenesis. Response surface methodology was applied to determine the optimal processing condition that gave maxim...
journal_title:Journal of medicinal food
pub_type: 杂志文章
doi:10.1089/jmf.2012.2623
更新日期:2013-06-01 00:00:00
abstract::Premature ejaculation (PE) is one of the foremost sex-related health problems among men. The global occurrence ranges from 20% to 30%, according to various studies. PE has a great impact on the men's quality of life, with deleterious effects such as embarrassment, frustration, and feeling of incompetence. Considering ...
journal_title:Journal of medicinal food
pub_type: 杂志文章
doi:10.1089/jmf.2019.4661
更新日期:2020-09-01 00:00:00
abstract::Mineral contents of some tea and their infusions drunk in Turkey were established by inductively coupled plasma atomic emission spectrometry. The Al, Ca, K, Mg, Mn, P, and S contents were very high in both infusions and tea (i.e., pieces of the tea plant). The As, Cd, Cr, Li, Pb, and Se contents of infusion and tea we...
journal_title:Journal of medicinal food
pub_type: 杂志文章
doi:10.1089/jmf.2006.9.123
更新日期:2006-04-01 00:00:00
abstract::The anti-ulcer potentials of aqueous (AE) and methanol (ME) extracts of whole unripe Carica papaya fruit were evaluated using ethanol- and indomethacin-induced gastric ulcer models in rats. The effect of the extracts on small intestinal propulsion was also investigated. The extracts significantly reduced the ulcer ind...
journal_title:Journal of medicinal food
pub_type: 杂志文章
doi:10.1089/jmf.2008.0197
更新日期:2009-12-01 00:00:00
abstract::Enzymatic hydrolysates of Laminaria japonica were evaluated for antioxidative activities using hydroxyl radical scavenging activity and protective effects against H(2)O(2)-induced DNA and cell damage. In addition, activities of antioxidative enzymes, including catalase, glutathione peroxidase, and glutathione S-transf...
journal_title:Journal of medicinal food
pub_type: 杂志文章
doi:10.1089/jmf.2007.0675
更新日期:2009-02-01 00:00:00
abstract::Nuclear factor E2-related factor 2 (Nrf2) is the master regulator of antioxidant enzymes and is known to act on the nuclear factor kappa-light-chain-enhancer of activated B cell (NF-κB) signaling pathway. Few studies have examined the bioactivity of halleridone. Herein, we investigated whether halleridone, which was i...
journal_title:Journal of medicinal food
pub_type: 杂志文章
doi:10.1089/jmf.2017.3949
更新日期:2017-11-01 00:00:00
abstract::Colon cancer is the second most common cancer among men and women worldwide. We investigated the effect of red chilli (Capsicum annum L.), cumin (Cuminum cyminum L.), and black pepper (Piper nigrum L.) on colon cancer induced in rats by a colon-specific carcinogen, 1,2-dimethylhydrazine (DMH). Colon cancer was induced...
journal_title:Journal of medicinal food
pub_type: 杂志文章
doi:10.1089/jmf.2006.9.237
更新日期:2006-07-01 00:00:00
abstract::The immune response is stimulated to protect the body from external antigens and is controlled by several types of immune cells. In the present study, the immunomodulatory effects of Curcuma longa L., purple sweet potato, and mixtures of the two (CPM) were investigated in C57BL/6 mice infected with LP-BM5 murine leuke...
journal_title:Journal of medicinal food
pub_type: 杂志文章
doi:10.1089/jmf.2017.4093
更新日期:2018-07-01 00:00:00
abstract::We previously reported hyperproliferation and hyperplasia in C57Bl/6 mouse mammary gland after feeding a Western-style diet (WD); these findings decreased after supplementing WD with increased calcium and vitamin D(3). We now again fortified WD with increased calcium and vitamin D(3) from two sources: (1) a food sourc...
journal_title:Journal of medicinal food
pub_type: 杂志文章
doi:10.1089/jmf.2007.619
更新日期:2008-06-01 00:00:00
abstract::Overwhelming evidence indicates that consumption of fruits and vegetables with antioxidant properties correlates with reduced risk for cancers, including leukemia. Carrots contain beneficial agents, such as β-carotene and polyacetylenes, which could be effective in the treatment of leukemia. This study investigated th...
journal_title:Journal of medicinal food
pub_type: 杂志文章
doi:10.1089/jmf.2010.0284
更新日期:2011-11-01 00:00:00
abstract::Fermentation has shown to be an effective technique in bioactive peptides release. That is why in this study antihypertensive, antithrombotic, and antioxidant activity was evaluated during amaranth proteins fermentation with Lactobacillus casei Shirota and Streptococcus thermophilus 54102 in mono and combined culture....
journal_title:Journal of medicinal food
pub_type: 杂志文章
doi:10.1089/jmf.2019.0039
更新日期:2019-10-01 00:00:00
abstract::Broccoli belongs to a group of cruciferous vegetables characterized by its content of glucosinolates, secondary metabolites that, upon hydrolysis, release bioactive isothiocyanates (ITCs). Sulforaphane, the major ITC from broccoli, is believed to protect the body from cancer by induction of detoxification enzymes such...
journal_title:Journal of medicinal food
pub_type: 杂志文章
doi:10.1089/109662004322984770
更新日期:2004-04-01 00:00:00
abstract::The present study was carried out to assess the influence of sesame oil on blood glucose, lipid peroxidation, and status of antioxidants in normal and streptozotocin (STZ) diabetic rats. Diabetes was induced in adult female albino Wistar rats weighing 180-200 g by administration of STZ (40 mg/kg of body weight) intrap...
journal_title:Journal of medicinal food
pub_type: 杂志文章
doi:10.1089/jmf.2005.8.377
更新日期:2005-10-01 00:00:00
abstract::Garlic protects against degenerative diseases such as hyperlipidemia and cardiovascular diseases. However, raw garlic has a strong pungency, which is unpleasant. In this study, we examined the effect of high temperature/high pressure-processed garlic on plasma lipid profiles in rats. Sprague-Dawley rats were fed a nor...
journal_title:Journal of medicinal food
pub_type: 杂志文章
doi:10.1089/jmf.2011.1922
更新日期:2012-05-01 00:00:00
abstract::In this study, we investigated the antioxidant and protective effect of Lindera glauca stem (LGS) extracts against oxidative stress. We compared antioxidant properties of water extract (LGSW) with ethanol extract (LGSE) by determining the contents responsible for antioxidant activities such as polyphenols and flavonoi...
journal_title:Journal of medicinal food
pub_type: 杂志文章
doi:10.1089/jmf.2018.4289
更新日期:2019-05-01 00:00:00
abstract::Frondoside A, a major triterpene glycoside from North Atlantic commercially harvested sea cucumber Cucumaria frondosa, possesses strong immunomodulatory properties in subtoxic doses. Frondoside A stimulates lysosomal activity of mouse macrophages in vivo at a maximal effective stimulatory dose of 0.2 microg per mouse ...
journal_title:Journal of medicinal food
pub_type: 杂志文章
doi:10.1089/jmf.2007.0530
更新日期:2008-09-01 00:00:00
abstract::This study sought to characterize the effects of some citrus fruit juices (shaddock [Citrus maxima], grapefruit [Citrus paradisii], lemon [Citrus limoni], orange [Citrus sinensis], and tangerine [Citrus reticulata]) on acetylcholinesterase activity in vitro. The total phenolic content, radical scavenging abilities, an...
journal_title:Journal of medicinal food
pub_type: 杂志文章
doi:10.1089/jmf.2011.0226
更新日期:2012-05-01 00:00:00
abstract::The herbal remedy Zingiber officinale (ginger root) has been used for perhaps thousands of years in the Far East to treat inflammatory diseases, including osteoarthritis. However, the anti-arthritic effect of ginger root has never been evaluated on osteoarthrotic cartilage of sow. The objective of this study was to in...
journal_title:Journal of medicinal food
pub_type: 杂志文章
doi:10.1089/109662003772519877
更新日期:2003-01-01 00:00:00
abstract::Polyphenol-rich foods, such as fruits and vegetables, are protective against cardiovascular diseases, but the mechanisms of the beneficial effects are still unknown. The goal of this research was to clarify actions of procyanidin trimer (C1) in rat aortic endothelial cells (RAECs). Procyanidin C1 at concentrations up ...
journal_title:Journal of medicinal food
pub_type: 杂志文章
doi:10.1089/jmf.2012.2297
更新日期:2012-11-01 00:00:00
abstract::Soy products are mainly composed of proteins, phytochemicals such as isoflavones, soy lipids, and carbohydrates. It is unclear whether an individual component alone or a combined effect of multiple bioactive compounds contributes to the beneficial properties of soy. We investigated the effect of dietary genistein (the...
journal_title:Journal of medicinal food
pub_type: 杂志文章
doi:10.1089/jmf.2006.9.459
更新日期:2006-01-01 00:00:00
abstract::This study evaluated the antioxidant and protective effects of bioactive compounds isolated from pressurized steam-treated Corni Fructus (PSC). We had previously tested the protective effects of the furan fraction containing 5-hydroxymethylfurfural (5-HMF), polyphenol fraction containing gallic acid, and iridoid glyco...
journal_title:Journal of medicinal food
pub_type: 杂志文章
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更新日期:2018-11-01 00:00:00
abstract::Capsicum baccatum is the most consumed red pepper species in Brazil. Our previous studies demonstrated the anti-inflammatory properties of its crude extract, whose activity is yet to be fully characterized. Herein, we examined the anti-inflammatory in vivo effects of enriched extracts obtained through bioguided fracti...
journal_title:Journal of medicinal food
pub_type: 杂志文章
doi:10.1089/jmf.2015.0101
更新日期:2016-08-01 00:00:00
abstract::This study was designed to investigate the effect of heating, storage, and ultraviolet exposure on antimicrobial activity of garlic juice and its bacteriocidal activity against common human pathogens. Antimicrobial activity of fresh garlic juice was tested against Escherichia coli, Staphylococcus aureus, Streptococcus...
journal_title:Journal of medicinal food
pub_type: 杂志文章
doi:10.1089/jmf.2005.067
更新日期:2007-03-01 00:00:00
abstract::Momordica charantia is used to treat various diseases, including inflammatory conditions. Previous reports indicated that the extract of this plant inhibits activation of nuclear transcription factor-κB (NF-κB) but activates peroxisome proliferator-activated receptor (PPAR). Additionally, cucurbitane-type triterpene g...
journal_title:Journal of medicinal food
pub_type: 杂志文章
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更新日期:2012-04-01 00:00:00
abstract::Aqueous extracts of Gynura procumbens (Lour.) Merr. were orally administered to spontaneously hypertensive (SHR) rats for 4 weeks, and antihypertensive effects were determined. Oral administration of 500 mg/kg of G. procumbens (Lour.) Merr. extract (GPE) resulted in significantly lower blood pressure in SHR rats compa...
journal_title:Journal of medicinal food
pub_type: 杂志文章
doi:10.1089/jmf.2006.9.587
更新日期:2006-01-01 00:00:00
abstract::Antioxidant capacity and polyphenolic content of leaf infusions prepared from six highbush blueberry cultivars (Vaccinium corymbosum L.), one wild lowbush blueberry cultivar (Vaccinium myrtillus L.), and one commercially available mix of genotypes were determined. In order to simulate household tea preparation conditi...
journal_title:Journal of medicinal food
pub_type: 杂志文章
doi:10.1089/jmf.2008.0081
更新日期:2009-06-01 00:00:00