Effect of ectasia size or the ectasia ratio on the thrombosis in myocardial infarction frame count in patients with isolated coronary artery ectasia.

Abstract:

:Coronary blood flow was quantified using the thrombosis in myocardial infarction (TIMI) frame-count method. This measurement has been significantly correlated with flow velocity measured invasively by use of a Doppler flow wire. Coronary artery ectasia or aneurysm (CEA) is thought to be present in patients with a slow blood flow. In this study, we aimed to assess the relationship between the ectasia size or ectasia ratio and TIMI frame count in patients with CEA. The study population included 58 patients with isolated CEA of the right coronary artery. In patients with CEA, an ectasia ratio was calculated as diameter of the ectatic segment/diameter of the adjacent normal segment. According to the ectasia ratio, ectatic vessels were divided into two groups: ectasias with a 1.5- to 2.0-fold increase (group A) and more than 2.0-fold increase (group B) in normal vessel diameter. Patients with a significant stenotic lesion (>50%) in the ectatic vessel were excluded. The control group was formed from a matched population of 35 patients with angiographically proven normal coronary arteries. Characteristics of the ectasia and control groups are similar. The TIMI frame counts for the right coronary artery (RCA) were significantly higher in the ectasia group as compared with the control group (43 +/- 12 vs 23 +/- 8, P < 0.001). The ectasia group had 38 patients in group A and 20 patients in group B. The TIMI frame counts were significantly higher in group B than in group A (43 +/- 10 vs 51 +/- 15, P < 0.05). The TIMI frame count of the RCA showed a significant correlation with the ectasia ratio and the maximum diameter of the ectatic segment (r = 0.578, P < 0.001 and r = 0.435, P < 0.001, respectively). Our data suggest that TIMI frame count measurement depends on the ectasia size or ectasia ratio, and an increased ectasia ratio is markedly associated with decreased TIMI frame counts in patients with CEA.

journal_name

Heart Vessels

journal_title

Heart and vessels

authors

Kosar F,Acikgoz N,Sahin I,Topal E,Aksoy Y,Cehreli S

doi

10.1007/s00380-005-0831-y

subject

Has Abstract

pub_date

2005-09-01 00:00:00

pages

199-202

issue

5

eissn

0910-8327

issn

1615-2573

journal_volume

20

pub_type

杂志文章
  • Factors related to in-hospital heart failure are very different for unstable angina and non-ST elevation myocardial infarction.

    abstract::Non-ST-elevation myocardial infarction (NSTEMI) and unstable angina (UA) resulted in different degrees of damage to the heart muscle, and yet, when factors related to in-hospital outcomes were examined, these two subsets were often lumped together as non-STelevation acute coronary syndrome. Therefore, we investigated ...

    journal_title:Heart and vessels

    pub_type: 杂志文章,多中心研究

    doi:10.1007/s00380-008-1141-y

    authors: Saejueng B,Yipintsoi T,Chaisuksuwan R,Kehasukcharoen W,Boonsom W,Kanjanavanit R,Thai ACS-Registry group.

    更新日期:2009-11-01 00:00:00

  • Functional and metabolic responses of the isolated rat heart to changes in circulating inorganic phosphate concentration.

    abstract::Normoxic isolated rat hearts were perfused for 30 or 60 min with Krebs-Henseleit bicarbonate buffer (KHB) (in which the Pi concentration was adjusted to 0, 1.2, 2.4, or 10 mM) in both the presence and the absence of glucose as exogenous substrate. Functional performance and coronary flow were monitored throughout the ...

    journal_title:Heart and vessels

    pub_type: 杂志文章

    doi:10.1007/BF02058588

    authors: Humphrey SM,Armiger LC,Holliss DG,Buckman JE

    更新日期:1988-01-01 00:00:00

  • Echocardiographic surrogates of right atrial pressure in pulmonary hypertension.

    abstract::Right atrial pressure (RAP), a representative parameter of right heart failure, is very important for prognostic evaluation and risk assessment in pulmonary hypertension. However, its measurement requires invasive cardiac catheterization. In this study, we determined the most accurate echocardiographic surrogate of ca...

    journal_title:Heart and vessels

    pub_type: 杂志文章

    doi:10.1007/s00380-018-1264-8

    authors: Watanabe R,Amano H,Saito F,Toyoda S,Sakuma M,Abe S,Nakajima T,Inoue T

    更新日期:2019-03-01 00:00:00

  • Morphological characteristics of optical coherence tomography defined plaque fissure in patients with acute coronary syndrome.

    abstract::We assessed the plaque disruption in 245 consecutive patients with acute coronary syndrome undergoing percutaneous coronary intervention. The plaque fissure was diagnosed with optical coherence tomography, and intravascular ultrasound was used to determine arterial remodeling. Of them, 26 fissures were found in this s...

    journal_title:Heart and vessels

    pub_type: 杂志文章

    doi:10.1007/s00380-018-1271-9

    authors: Goyal M,Kim SW,Mishra S,Sharmin S,Won H,Cho I,Jung MK,Shin SY,Lee KJ,Kim TH,Kim CJ,Lee WS

    更新日期:2019-03-01 00:00:00

  • Recent therapeutic strategy for sustained ventricular tachycardia in Japan.

    abstract::We investigated the therapeutic principles and strategies to treat sustained ventricular tachycardia (SVT) as five leading medical institutions in the Tokyo area and summarized the present situation of SVT treatment in Japan. Catheter ablation (ABL) has been almost established to be effective in idiopathic ventricular...

    journal_title:Heart and vessels

    pub_type: 杂志文章

    doi:

    authors: Ogura H,Katoh T,Kasanuki H,Iinuma H,Ozawa Y,Majima S,Hayakawa H

    更新日期:1997-01-01 00:00:00

  • Serum uric acid levels and long-term outcomes in chronic kidney disease.

    abstract::Hyperuricemia is common in chronic kidney disease (CKD), but data regarding the relationship between serum uric acid levels and the long-term outcomes of CKD patients have been limited. The present study evaluated the associations between baseline serum uric acid levels with mortality and end-stage renal disease (ESRD...

    journal_title:Heart and vessels

    pub_type: 杂志文章

    doi:10.1007/s00380-013-0396-0

    authors: Miyaoka T,Mochizuki T,Takei T,Tsuchiya K,Nitta K

    更新日期:2014-07-01 00:00:00

  • Association of serum microRNA-21 levels with Visfatin, inflammation, and acute coronary syndromes.

    abstract::MicroRNAs (miRNAs) are short non-coding RNAs that regulate gene expression. It seems that microRNA-21 (miR-21) and Visfatin, a novel adipocytokine, play roles in inflammation and atherosclerosis. The aim of this study was to investigate the association of miR-21 with Visfatin, inflammation, atherosclerosis and acute c...

    journal_title:Heart and vessels

    pub_type: 杂志文章

    doi:10.1007/s00380-016-0913-z

    authors: Darabi F,Aghaei M,Movahedian A,Elahifar A,Pourmoghadas A,Sarrafzadegan N

    更新日期:2017-05-01 00:00:00

  • Vascular restenosis in coronary artery bypass grafting might be associated with VEGF-C/VEGFR-3 signaling pathway.

    abstract::The vascular endothelial growth factor (VEGF) family of peptides and caveolins (CAVs) are reported to contribute, in early graft failure in patients, a coronary artery bypass grafting (CABG). To investigate the possible association of ultimate luminal occlusion to VEGFs and CAVs expression, a functional analysis (base...

    journal_title:Heart and vessels

    pub_type: 杂志文章

    doi:10.1007/s00380-018-1158-9

    authors: Podemska-Jedrzejczak Z,Malinska A,Sujka-Kordowska P,Nowicki M,Puslecki M,Jemielity M,Perek B

    更新日期:2018-09-01 00:00:00

  • Chronotropic incompetence to exercise in anorexia nervosa patients during the body-weight recovery phase as an index of insufficient treatment.

    abstract::Resting bradycardia is an important symptom for early diagnosis of anorexia nervosa (AN) during weight loss, and it improves with body-weight recovery. However, chronotropic incompetence (CI) in exercise is observed in some patients with AN despite amelioration of resting bradycardia in the recovery phase. We examined...

    journal_title:Heart and vessels

    pub_type: 杂志文章

    doi:10.1007/s00380-018-1282-6

    authors: Yoshida Y,Maeda J,Fukushima H,Tokita N,Yamagishi H,Tokumura M

    更新日期:2019-04-01 00:00:00

  • Higher visit-to-visit intra-dialytic blood pressure is associated with the progression of aortic valve stenosis in chronic hemodialysis patients.

    abstract::Aortic valve stenosis (AS) is a frequent complication contributing to poor prognosis in chronic hemodialysis (CHD) patients. High blood pressure (BP) is known to be associated with AS progression in the general population. In CHD patients, however, BP varies during and between hemodialysis sessions with ultrafiltratio...

    journal_title:Heart and vessels

    pub_type: 杂志文章

    doi:10.1007/s00380-015-0756-z

    authors: Norioka N,Iwata S,Yanagi S,Ishii H,Sugioka K,Kamimori K,Ota T,Di Tullio MR,Homma S,Yoshiyama M

    更新日期:2016-09-01 00:00:00

  • Aldosterone induces circadian gene expression of clock genes in H9c2 cardiomyoblasts.

    abstract::We examined mRNA expression of the clock genes (Per1, Per2, and Bmal1) and PAI-1 (plasminogen activator inhibitor-1) after aldosterone treatment every 4 h up to 48 h in H9c2 cardiomyoblasts by reverse transcription-polymerase chain reaction. To block the MR (mineralocorticoid receptor), the MR antagonist, spironolacto...

    journal_title:Heart and vessels

    pub_type: 杂志文章

    doi:10.1007/s00380-006-0968-3

    authors: Tanaka K,Ashizawa N,Kawano H,Sato O,Seto S,Nishihara E,Terazono H,Isomoto S,Shinohara K,Yano K

    更新日期:2007-07-01 00:00:00

  • More coronary artery stenosis, more cerebral artery stenosis? A simultaneous angiographic study discloses their strong correlation.

    abstract::Cerebral artery stenosis (CAS) has the same pathogenesis as coronary artery disease (CAD), but the coexistence of these two diseases has been rarely reported. To detect coexistent CAS in CAD patients, we conducted a study of simultaneous coronary and cerebral angiography. Of the 663 consecutive newly diagnosed CAD pat...

    journal_title:Heart and vessels

    pub_type: 杂志文章

    doi:10.1007/s00380-006-0971-8

    authors: Li AH,Chu YT,Yang LH,Chen KC,Chu SH

    更新日期:2007-09-01 00:00:00

  • Influence of mild cognitive impairment on activities of daily living in patients with cardiovascular disease.

    abstract::Activities of daily living (ADL) are maintained in patients with mild cognitive impairment (MCI), but, in patients with cardiovascular disease, ADL may have already declined. MCI combined with cardiac disease may accentuate the decline of ADL in these patients. Because the relationship between MCI and ADL in patients ...

    journal_title:Heart and vessels

    pub_type: 杂志文章

    doi:10.1007/s00380-019-01437-7

    authors: Ishihara K,Izawa KP,Kitamura M,Shimogai T,Kanejima Y,Morisawa T,Shimizu I

    更新日期:2019-12-01 00:00:00

  • History of gastroesophageal reflux disease in patients with suspected coronary artery disease.

    abstract::It is well known that patients with gastroesophageal reflux disease (GERD) experience GERD-related chest pain, but little is known about the relationship between GERD and coronary artery disease (CAD). We evaluated medical history of GERD in patients with suspected CAD and its association with types of CAD. We enrolle...

    journal_title:Heart and vessels

    pub_type: 杂志文章

    doi:10.1007/s00380-019-01413-1

    authors: Teragawa H,Oshita C,Ueda T

    更新日期:2019-10-01 00:00:00

  • Morphological and functional study of free arterial grafts.

    abstract::Morphological and functional changes of free arterial grafts in dogs were studied for 3 weeks after implantation and the changes were compared to those in implanted free vein grafts. In the arterial grafts, endothelial cells with abundant pinocytotic vesicles and some cytoplasmic folds were observed by transmission an...

    journal_title:Heart and vessels

    pub_type: 杂志文章

    doi:10.1007/BF01744868

    authors: Isomura T,Hisatomi K,Inuzuka H,Nishimi M,Hirano A,Ohishi K

    更新日期:1992-01-01 00:00:00

  • ZBTB17 loss-of-function mutation contributes to familial dilated cardiomyopathy.

    abstract::Dilated cardiomyopathy (DCM) is a common primary myocardial disease leading to congestive heart failure, arrhythmia and sudden cardiac death. Increasing studies demonstrate substantial genetic determinants for DCM. Nevertheless, DCM is of substantial genetic heterogeneity, and the genetic basis for DCM in most patient...

    journal_title:Heart and vessels

    pub_type: 杂志文章

    doi:10.1007/s00380-017-1110-4

    authors: Sun YM,Wang J,Xu YJ,Wang XH,Yuan F,Liu H,Li RG,Zhang M,Li YJ,Shi HY,Zhao L,Qiu XB,Qu XK,Yang YQ

    更新日期:2018-07-01 00:00:00

  • L/N-type Ca2+ channels blocker cilnidipine ameliorated the repolarization abnormality in a chronic hemodialysis patient.

    abstract::A 53-year-old woman with end-stage renal disease and hypertension, who had received regular artificial hemodialysis for 10 years, has been treated with candesartan in a dose of 8 mg/day against her hypertension, but premature ventricular contractions were often observed during the hemodialysis. QT interval was 445 ms ...

    journal_title:Heart and vessels

    pub_type: 杂志文章

    doi:10.1007/s00380-016-0865-3

    authors: Cao X,Nakamura Y,Wada T,Izumi-Nakaseko H,Ando K,Sugiyama A

    更新日期:2017-01-01 00:00:00

  • Cardiovascular medicine heart failure (CVM-HF) index as prognostic model for candidates to MitraClip therapy.

    abstract::Transcatheter MitraClip repair is a new tool for the management of severe mitral regurgitation in patients at very high risk for conventional surgery. Aim of our study was reporting one-year clinical outcomes in candidates to MitraClip procedures, divided into three groups according to the cardiovascular medicine hear...

    journal_title:Heart and vessels

    pub_type: 杂志文章

    doi:10.1007/s00380-015-0772-z

    authors: Ussia GP,Cammalleri V,Mazzotta E,Pascuzzo G,Muscoli S,Marchei M,Macrini M,Anceschi A,Romeo F

    更新日期:2016-10-01 00:00:00

  • Relationship between aerobic fitness and progression of coronary atherosclerosis.

    abstract::Cross-sectional data suggest that the degree of coronary atherosclerosis is associated with aerobic fitness. However, there are limited longitudinal data addressing whether aerobic fitness is a predictor of coronary atherosclerosis progression. This study investigated whether peak oxygen consumption is related to a lo...

    journal_title:Heart and vessels

    pub_type: 杂志文章

    doi:10.1007/s00380-015-0745-2

    authors: Sung J,Cho SJ,Choe YH,Yoo S,Woo KG,Choi YH,Hong KP

    更新日期:2016-09-01 00:00:00

  • Sudden death due to aortic rupture in acromegaly.

    abstract::Acromegaly, when left untreated, is associated with premature mortality which is chiefly related to cardiovascular complications. We report on a 50-year-old acromegalic woman, resistant to therapy, who died suddenly because of thoracic aortic rupture and massive bleeding into the left pleural space. The postmortem exa...

    journal_title:Heart and vessels

    pub_type: 杂志文章

    doi:10.1007/s00380-007-1012-y

    authors: Maffei P,Menegazzo C,Michelotto M,Salmaso R,Martini C,De Carlo E,Carli M,Barban M,Fassina A,Vettor R,Sicolo N

    更新日期:2008-01-01 00:00:00

  • Soluble urokinase-type plasminogen activator receptor represents exercise tolerance and predicts adverse cardiac events in patients with heart failure.

    abstract::Soluble urokinase-type plasminogen activator receptor (suPAR) is a membrane-binding protein that is released into the blood stream by immune activation. Recent reports suggest that circulating suPAR levels are associated with adverse cardiovascular outcomes. Exercise tolerance is an independent predictor of prognosis ...

    journal_title:Heart and vessels

    pub_type: 杂志文章

    doi:10.1007/s00380-019-01538-3

    authors: Ishikawa H,Izumiya Y,Shibata A,Ichikawa Y,Yamaguchi T,Yamaguchi Y,Kitada R,Iwata S,Ehara S,Tomita S,Hanatani A,Yoshiyama M

    更新日期:2020-05-01 00:00:00

  • Hypocellularity and insufficient expression of angiogenic factors in implanted autologous bone marrow in patients with chronic critical limb ischemia.

    abstract::The aim of this study was to identify the clinical parameters of absolutely poor-prognosis patients with chronic critical limb ischemia (AP-CLI). Sixteen no-option CLI patients with arteriosclerosis obliterans: ASO (nine) and non-ASO patients (seven) treated with bone marrow-mononuclear cell implantation (BMI) were an...

    journal_title:Heart and vessels

    pub_type: 临床试验,杂志文章

    doi:10.1007/s00380-011-0125-5

    authors: Oda M,Toba K,Kato K,Ozawa T,Yanagawa T,Ikarashi N,Takayama T,Suzuki T,Hanawa H,Masuko M,Kobayashi H,Aizawa Y

    更新日期:2012-01-01 00:00:00

  • Low serum eicosapentaenoic acid level is a risk for ventricular arrhythmia in patients with acute myocardial infarction: a possible link to J-waves.

    abstract::Eicosapentaenoic acid (EPA) has antiarrhythmic effects. The J-wave on an electrocardiogram is associated with a high incidence of ventricular tachycardia/fibrillation (VT/VF). We evaluated relationships between EPA and J-waves, and their involvement in the occurrence of VT/VF in acute myocardial infarction (AMI). Two ...

    journal_title:Heart and vessels

    pub_type: 杂志文章

    doi:10.1007/s00380-013-0435-x

    authors: Endo T,Tomita H,Higuma T,Abe N,Kushibiki M,Saitoh S,Yamada M,Yokota T,Echizen T,Yokoyama H,Tateyama S,Suzuki A,Ishida Y,Murakami K,Osanai T,Okumura K

    更新日期:2014-11-01 00:00:00

  • Vasoconstrictor effects of endogenous digitalis-like factors extracted from urine of hypertensive patients.

    abstract::The vascular effects of endogenous digitalis-like factors (EDLFs) extracted from the urine of hypertensive patients were investigated in isolated and perfused intermediate auricular and mesenteric arterial preparations of dogs. EDLFs produced a transient vasoconstriction in a dose-related manner in intermediate auricu...

    journal_title:Heart and vessels

    pub_type: 杂志文章

    doi:10.1007/BF02058788

    authors: Chiba S,Tsukada M,Katsuyama Y,Tada A,Zenda H

    更新日期:1987-01-01 00:00:00

  • Argatroban as an alternative anticoagulant for patients with heparin allergy during coronary bypass surgery.

    abstract::Although heparin allergy is a rare but well-documented entity, anticoagulation management for cardiac surgery in patients with the heparin allergy has not been established due to its rarity. Here we report a case that shows our anticoagulation strategy during a coronary bypass operation. A 67-year-old man with unstabl...

    journal_title:Heart and vessels

    pub_type: 杂志文章

    doi:10.1007/s003800300006

    authors: Ohno H,Higashidate M,Yokosuka T

    更新日期:2003-03-01 00:00:00

  • Relation of omega-3 fatty acid and C-reactive protein to peripheral artery disease in patients with coronary artery disease.

    abstract::Eicosapentaenoic acid (EPA), a member of the omega-3 polyunsaturated fatty acid family, prevents cardiovascular disease. C-reactive protein (CRP) is a marker of inflammation, which promotes atherosclerosis. The aim of this study was to investigate the relationship among EPA, CRP, and the prevalence of peripheral arter...

    journal_title:Heart and vessels

    pub_type: 杂志文章

    doi:10.1007/s00380-013-0384-4

    authors: Sugiura T,Yoshikawa D,Ishii H,Suzuki S,Kumagai S,Inoue Y,Okumura S,Isobe S,Hayashi M,Ando H,Amano T,Murohara T

    更新日期:2014-07-01 00:00:00

  • A pathologic analysis of the outcome following heart-lung transplantation: an autopsy study of 22 recipients.

    abstract::Between 1987 and 1989, twenty-two patients who received combined heart-lung transplantation were autopsied at La Pitie Salpetriere Hospital in Paris. With the exception of two recipients who survived for 2 months and 4 months, respectively, the majority of the patients died in the early postoperative period (the mean ...

    journal_title:Heart and vessels

    pub_type: 杂志文章

    doi:10.1007/BF02125099

    authors: Ishibashi-Ueda H,Chomette G,Delcourt A,Auriol M,Le Charpentier Y,Cabrol C

    更新日期:1991-01-01 00:00:00

  • Systolic pressure-volume area (PVA) as the energy of contraction in Starling's law of the heart.

    abstract::We have theoretically proposed "systolic pressure-volume area" (PVA) as a measure of total mechanical energy generated by ventricular contraction. We then experimentally showed that PVA closely correlates with left ventricular oxygen consumption (Vo2) regardless of ventricular loading conditions in a stable contractil...

    journal_title:Heart and vessels

    pub_type: 杂志文章

    doi:10.1007/BF02058751

    authors: Suga H,Goto Y,Futaki S,Kawaguchi O,Yaku H,Hata K,Takasago T

    更新日期:1991-01-01 00:00:00

  • Aortic annulus angulation does not attenuate procedural success of transcatheter aortic valve replacement using a novel self-expanding bioprosthesis.

    abstract::The objectives of the study were to evaluate the impact of aortic angulation (AA) on success of transcatheter aortic valve replacement (TAVR) with a new generation self-expandable prosthesis (Medtronic Evolut R®). Specific anatomical conditions, such as for example the presence of a horizontal aorta with elevated AA, ...

    journal_title:Heart and vessels

    pub_type: 杂志文章

    doi:10.1007/s00380-019-01436-8

    authors: D'Ancona G,Kische S,El-Mawardy M,Dißmann M,Heinze H,Zohlnhöfer-Momm D,Gürer H,Ince H

    更新日期:2019-12-01 00:00:00

  • Agonist-independent modulation of L-type Ca currents by basal Gs protein activities in single guinea pig ventricular myocytes.

    abstract::The modulation of L-type Ca2+ currents (I(Ca,L)) by the basal activities of G proteins was studied in adult guinea pig ventricular myocytes by whole-cell patch-clamp techniques. With intrapipette guanosine triphosphate (GTP) (100 microM), a specific inhibition of G1 proteins by pertussis toxin (PTX) produced an increa...

    journal_title:Heart and vessels

    pub_type: 杂志文章

    doi:10.1007/s003800070013

    authors: Makita T,Horie M,Xie LH,Okada Y,Sasayama S

    更新日期:2000-01-01 00:00:00