The effect of peripheral resistance on impedance cardiography measurements in the anesthetized dog.

abstract：UNLABELLED:One-lung ventilation (OLV) induces an increase in pulmonary shunt sometimes associated with a decrease in PaO2 despite ventilation with 100% oxygen. PaO2 improvement has been reported in one-lung ventilated animals receiving IV almitrine, a pulmonary vasoconstrictor. We evaluated the ability of almitrine to ...

journal_title：Anesthesia and analgesia

authors： Moutafis M,Dalibon N,Liu N,Kuhlman G,Fischler M

更新日期：2002-04-01 00:00:00

abstract：:Dantrolene effectively treats malignant hyperthermia (MH) hut the current form, Dantrium, must be dissolved to a 0.33 mg/mL, pH 9.5 solution. This study describes lecithin-coated microcrystal formulations of sodium dantrolene (MC-NaD) and neutral dantrolene (MC-D) which reconstitute to 200 mg/mL within 1 min. In rats,...

journal_title：Anesthesia and analgesia

authors： Karan SM,Lojeski EW,Haynes DH,Bina S,Wesche DL,Boedeker BH,Muldoon SM

更新日期：1996-04-01 00:00:00

abstract：UNLABELLED:We tested the hypothesis that electro-acupuncture at the Zusanli, Yanglingquan, and Kunlun acupuncture points on the legs decreases anesthetic requirement. Fourteen young, healthy volunteers were anesthetized with desflurane on two separate days. Needle electrodes were positioned at the three acupuncture poi...

journal_title：Anesthesia and analgesia

authors： Morioka N,Akça O,Doufas AG,Chernyak G,Sessler DI

更新日期：2002-07-01 00:00:00

abstract：UNLABELLED:Isoflurane reduces myocardial infarct size during early reperfusion by activating phosphatidylinositol-3-kinase (PI3K) signaling. We tested the hypothesis that this cardioprotection against reperfusion injury is enhanced by morphine and that a decrease in apoptosis plays a role in preservation of myocardial ...

journal_title：Anesthesia and analgesia

authors： Weihrauch D,Krolikowski JG,Bienengraeber M,Kersten JR,Warltier DC,Pagel PS

更新日期：2005-10-01 00:00:00

abstract：UNLABELLED:This study was performed to evaluate both the effects of pentobarbital on disruption of the blood-brain barrier (BBB) by hyperosmolar mannitol and the relationship between its effect on blood pressure and the integrity of the BBB. Under isoflurane anesthesia, rats in the control group were infused with 25% m...

journal_title：Anesthesia and analgesia

authors： Chi OZ,Chun TW,Liu X,Weiss HR

更新日期：1998-06-01 00:00:00

abstract：BACKGROUND:In patients with mitral regurgitation (MR), the effective regurgitant orifice area can be estimated by measuring the vena contracta area (VCA). We hypothesize that the VCA has characteristic temporal dynamics related to the underlying mechanism of functional mitral regurgitation (FMR) versus degenerative mit...

journal_title：Anesthesia and analgesia

authors： Cobey FC,Ashihkmina E,Edrich T,Fox J,Shook D,Bollen B,Breeze JL,Ursprung WW,Shernan SK

更新日期：2016-02-01 00:00:00

abstract：:We have recently reported a chronic allodynialike symptom in rats after ischemic spinal cord injury. This pain-related behavior is resistant to a number of pharmacologic treatments, including morphine, clonidine, carbamazepine, baclofen, and muscimol. In the present report, we present evidence indicating that systemic...

journal_title：Anesthesia and analgesia

authors： Xu XJ,Hao JX,Seiger A,Arnér S,Lindblom U,Wiesenfeld-Hallin Z

更新日期：1992-05-01 00:00:00

abstract：:The onset and intensity of blockade of the lumbosacral dermatomes after epidural anesthesia with alkalinized lidocaine were investigated in a randomized, double-blind study in 26 patients. Control subjects (n = 13) received 20 mL of 1.37% lidocaine (1.5% lidocaine plus 1 mL saline per 10 mL lidocaine) with added 1:200...

journal_title：Anesthesia and analgesia

authors： Benzon HT,Toleikis JR,Dixit P,Goodman I,Hill JA

更新日期：1993-02-01 00:00:00

abstract：UNLABELLED:We used a double-blind design to study urodynamic changes induced by mu-agonists (fentanyl, morphine), a partial mu-agonist antagonist (buprenorphine), a putative mu-antagonist, kappa-agonist (nalbuphine), and ketoprofen, an injectable nonsteroidal antiinflammatory drug. Men (20-55 yr old) were randomly assi...

journal_title：Anesthesia and analgesia

authors： Malinovsky JM,Le Normand L,Lepage JY,Malinge M,Cozian A,Pinaud M,Buzelin JM

更新日期：1998-08-01 00:00:00

abstract：:The understanding of anesthetic side effects on the heart has been hindered by the lack of sophisticated clinical models. Using micropatterned human-induced pluripotent stem cell-derived cardiomyocytes, we obtained cardiac muscle depressant profiles for propofol, etomidate, and our newly identified anesthetic compound...

journal_title：Anesthesia and analgesia

authors： Chang ACY,Chang ACH,Nicin L,Weber GJ,Holbrook C,Davies MF,Blau HM,Bertaccini EJ

更新日期：2020-01-01 00:00:00

abstract：:Fifty-three swine from the University of Missouri Sinclair Medical Research Farm were used in experimentation to determine their susceptibility to malignant hyperthermia, to determine appropriate anesthetic agents for susceptible swine and to investigate appropriate pharmaceutical agents which could protect against th...

journal_title：Anesthesia and analgesia

authors： Short CE,Paddleford RR,McGrath CJ,Williams CH

更新日期：1976-09-01 00:00:00

abstract：UNLABELLED:Because perfluorocarbon (PFC) liquid contacts closely with the alveolar capillaries during partial liquid ventilation (PLV), PLV with cold PFC may be used for the induction of hypothermia. Twenty rabbits were randomized to PFC-induced hypothermia (PH) (n = 7; core temperature 35 degrees +/- 1 degrees C), sur...

journal_title：Anesthesia and analgesia

authors： Hong SB,Koh Y,Shim TS,Lee SD,Kim WS,Kim DS,Kim WD,Lim CM

更新日期：2002-01-01 00:00:00

abstract：UNLABELLED:Previous studies of samples from cranial meninges have created doubts about the existence of a virtual subdural space. We examined the ultrastructure of spinal meninges from three human cadavers immediately after death to see whether there is a virtual subdural space at this level. The arachnoid mater had tw...

journal_title：Anesthesia and analgesia

authors： Reina MA,De Leon Casasola O,López A,De Andrés JA,Mora M,Fernández A

更新日期：2002-04-01 00:00:00

abstract：UNLABELLED:In this study, we compared the direct myocardial depressant effects of sevoflurane, isoflurane, and halothane and determined whether an L-type Ca2+ channel agonist, Bay K 8644, could attenuate the myocardial depression induced by these anesthetics in cultured neonatal rat ventricular myocytes. Ventricular my...

journal_title：Anesthesia and analgesia

authors： Kanaya N,Kawana S,Tsuchida H,Miyamoto A,Ohshika H,Namiki A

更新日期：1998-11-01 00:00:00

abstract：:Practicing anesthesiologists are at high risk of hepatitis B infection, but the risk for anesthesia residents has not been assessed. Anesthesia residents at seven universities were surveyed to study the epidemiology of hepatitis B in these trainees. Hepatitis B virus markers in serum were measured and data from questi...

journal_title：Anesthesia and analgesia

authors： Berry AJ,Isaacson IJ,Kane MA,Schatz GC,Clark BT,Beaupre P,Derrer S,Kapur P,Thompson J,Martin D

更新日期：1985-07-01 00:00:00

abstract：BACKGROUND:Recent attention to adverse effects of intensive care unit (ICU) sedation has led to the use of strategies that target a "lighter" depth of sedation. Among these strategies are "analgosedation" protocols, which prioritize pain management and preferentially use IV opioids before administration of continuously...

journal_title：Anesthesia and analgesia

authors： Faust AC,Rajan P,Sheperd LA,Alvarez CA,McCorstin P,Doebele RL

更新日期：2016-10-01 00:00:00

abstract：:Several observational and objective methods are available to assess sedation depth; however, data regarding their accuracy in differentiating deep sedation are limited. In this study we compared 3 sedation tools in children from birth to 18 yr of age and determined their relative value in detecting deep levels of seda...

journal_title：Anesthesia and analgesia

authors： Malviya S,Voepel-Lewis T,Tait AR

更新日期：2006-02-01 00:00:00

abstract：:We assessed the efficacy of patient-controlled analgesia (PCA) techniques for extended femoral nerve sheath block after total hip arthroplasty. Forty-five patients were divided into three groups of 15. Over 48 h, all patients received 0.125% bupivacaine with clonidine 1 microg/mL and sufentanil 0.1 microg/mL via a fem...

journal_title：Anesthesia and analgesia

authors： Singelyn FJ,Vanderelst PE,Gouverneur JM

更新日期：2001-02-01 00:00:00

abstract：:Adverse reactions to volatile anesthetics and depolarizing muscle relaxants can occur in patients with Duchenne muscular dystrophy (DMD) resulting in acute rhabdomyolysis and hyperkalemia. We report a case of hyperkalemic cardiac arrest after cardiac surgery using cardiopulmonary bypass in a child with unsuspected DMD...

journal_title：Anesthesia and analgesia

authors： Nathan A,Ganesh A,Godinez RI,Nicolson SC,Greeley WJ

更新日期：2005-03-01 00:00:00

abstract：UNLABELLED:Ketamine, a noncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist, has psychotomimetic activity. NMDA receptor antagonists cause morphological damage in the posterior cingulate cortex, which may be the brain region responsible for their psychotomimetic effects. Benzodiazepines are effective in preve...

journal_title：Anesthesia and analgesia

authors： Nagata A,Nakao S,Miyamoto E,Inada T,Tooyama I,Kimura H,Shingu K

更新日期：1998-12-01 00:00:00

abstract：:Serum cholinesterase levels were determined in 180 patients with carcinoma and in 146 normal subjects. Serum cholinesterase activity was significantly lower in patients suffering from cancer than in normal controls, though still within the normal range. The degree of depression of serum cholinesterase activity was inf...

journal_title：Anesthesia and analgesia

authors： Kaniaris P,Fassoulaki A,Liarmakopoulou K,Dermitzakis E

更新日期：1979-03-01 00:00:00

abstract：:We report a case of possible air embolism during a three-port pars plana vitrectomy and air-fluid exchange of the vitreous cavity of the eye. After the start of intraocular air flushing, sudden tachycardia, a decrease in oxygen saturation and end-tidal carbon dioxide tension, and a distinct "mill-wheel" murmur were ob...

journal_title：Anesthesia and analgesia

authors： Ledowski T,Kiese F,Jeglin S,Scholz J

更新日期：2005-06-01 00:00:00

abstract：:To investigate the possible role of atrial and brain natriuretic peptides (ANP and BNP) in the renal effects of mechanical ventilation with positive end-expiratory pressure (PEEP), we measured changes in plasma ANP and BNP levels during PEEP in patients undergoing subtotal esophagectomy. Application of 15 cm of H2O PE...

journal_title：Anesthesia and analgesia

authors： Shirakami G,Magaribuchi T,Shingu K,Suga S,Tamai S,Nakao K,Mori K

更新日期：1993-12-01 00:00:00

abstract：:A 50-micrograms/kg dose of fentanyl, given intravenously in divided doses to dogs under enflurane-nitrous oxide anesthesia caused sharp decreases in heart rate (HR), arterial blood pressure (AP), left ventricular dP/dt, and plasma levels of catecholamines. Naloxone, 20 micrograms/kg given 65-70 min later, completely a...

journal_title：Anesthesia and analgesia

authors： Flacke JW,Flacke WE,Bloor BC,Olewine S

更新日期：1983-03-01 00:00:00

abstract：:Windup is a progressive increase in responses of nociceptive spinal cord neurons to repeated electrical C fiber stimulation. We hypothesized that isoflurane would depress windup at approximately the minimum alveolar anesthetic concentration (MAC) required to suppress purposeful movement in response to noxious stimulat...

journal_title：Anesthesia and analgesia

authors： Jinks SL,Antognini JF,Dutton RC,Carstens E,Eger EI 2nd

更新日期：2004-11-01 00:00:00

abstract：BACKGROUND:A new benzodiazepine, remimazolam, which is rapidly metabolized by tissue esterases to an inactive metabolite, has been developed to permit a fast onset, a short, predictable duration of sedative action, and a more rapid recovery profile than currently available drugs. We report on modeling of the data and s...

journal_title：Anesthesia and analgesia

authors： Wiltshire HR,Kilpatrick GJ,Tilbrook GS,Borkett KM

更新日期：2012-08-01 00:00:00

abstract：BACKGROUND:We studied the effects that the lung recruitment maneuver (RM) and positive end-expiratory pressure (PEEP) have on the elimination of CO(2) per breath (Vtco(2,br)). METHODS:In 7 healthy and 7 lung-lavaged pigs at constant ventilation, PEEP was increased from 0 to 18 cm H(2)O and then decreased to 0 in steps...

journal_title：Anesthesia and analgesia

authors： Tusman G,Bohm SH,Suarez-Sipmann F,Scandurra A,Hedenstierna G

更新日期：2010-10-01 00:00:00

abstract：:There is precedent in medicine for recognizing and accepting intact decisional capacity and the subsequent ability to provide valid consent in one treatment domain, while simultaneously recognizing that the patient lacks decisional capacity in other domains. As such, obtaining consent for anesthesia for a surgical pro...

journal_title：Anesthesia and analgesia

authors： Marcucci C,Seagull FJ,Loreck D,Bourke DL,Sandson NB

更新日期：2010-02-01 00:00:00

abstract：:The anesthetic effect of lidocaine was evaluated in rats by determining the change in anesthetic requirement of cyclopropane MAC that was produced by blood concentrations of lidocaine in the clinically useful range. A linear reduction in anesthetic requirement was produced with concentrations up to 1 mug/ml. Further i...

journal_title：Anesthesia and analgesia

authors： DiFazio CA,Neiderlehner JR,Burney RG

更新日期：1976-11-01 00:00:00

abstract：:Stellate ganglion block (SGB) is an established procedure for the diagnosis and treatment of chronic pain. SGB results in an acute sympathetic denervation of a part of the left ventricular (LV) wall innervated by the blocked ganglion, which may impair regional contractility. The resulting imbalance of myocardial contr...

journal_title：Anesthesia and analgesia

authors： Schlack W,Schäfer S,Thämer V

更新日期：1994-12-01 00:00:00