Poor prognosis associated with thrombocytosis in patients with cervical cancer.

abstract：BACKGROUND:Estrogen receptor-alpha (ERalpha) is variably expressed in hepatocellular carcinoma (HCC) and is believed to be correlated with prognosis and survival. Recently, another estrogen receptor (ERbeta) has been identified, but its relevance in liver diseases is unknown. METHODS:The expression of ERbeta in the li...

journal_title：Cancer

authors： Iavarone M,Lampertico P,Seletti C,Francesca Donato M,Ronchi G,del Ninno E,Colombo M

更新日期：2003-08-01 00:00:00

abstract：BACKGROUND:Several histologic classifications of thymomas have been proposed, and attempts have been made to correlate the different histologic subtypes to clinical behavior and prognosis. Recently, Marino and Müller-Hermelink and Kirchner et al. proposed a new morphologic classification of thymomas based on the resemb...

journal_title：Cancer

authors： Quintanilla-Martinez L,Wilkins EW Jr,Choi N,Efird J,Hug E,Harris NL

更新日期：1994-07-15 00:00:00

abstract：:The only prophylaxis for ovarian cancer is oophorectomy, except in the very rare case when an ovarian cancer appears to arise from the mesothelial tissue of the abdominal cavity. It has been shown that women who have taken the oral contraceptive pill for 4 or 5 years decreases the incidence of ovarian cancer by approx...

journal_title：Cancer

authors： Barber HR

更新日期：1993-02-15 00:00:00

abstract：BACKGROUND:This survey documents the strategies used by pain control physicians in the selection of opioid drugs and routes of administration in the management of inpatients referred to a cancer pain service. METHODS:The following approaches were prospectively evaluated during the treatment of 100 consecutive inpatien...

journal_title：Cancer

authors： Cherny NJ,Chang V,Frager G,Ingham JM,Tiseo PJ,Popp B,Portenoy RK,Foley KM

更新日期：1995-10-01 00:00:00

abstract：BACKGROUND:Recent clinical trials have documented activity for combinations of chemotherapeutic agents that target the microtubular apparatus in patients with hormone-refractory prostate cancer. Taxol has a novel antimicrotubular mechanism, acting by stabilizing polymerized tubulin. METHODS:Twenty-three patients with ...

journal_title：Cancer

authors： Roth BJ,Yeap BY,Wilding G,Kasimis B,McLeod D,Loehrer PJ

更新日期：1993-10-15 00:00:00

abstract：BACKGROUND:The authors have noted that in cervical cytology specimens from perimenopausal and postmenopausal women, the diagnosis of atypical squamous cells of undetermined significance (ASC-US), as defined in the Bethesda system, is often not associated with a clinically evident lesion on follow-up. Reflex human papil...

journal_title：Cancer

authors： Johnston EI,Logani S

更新日期：2007-06-25 00:00:00

abstract：:In this study of 2092 women with cancer of the breast, those who had practiced breast self-examination (BSE) had earlier cancer than did those who had not practiced BSE. This was true for both black and white races, all educational and economic levels, each age group, and within each period of delay between first symp...

journal_title：Cancer

authors： Huguley CM Jr,Brown RL

更新日期：1981-03-01 00:00:00

abstract：BACKGROUND:Interleukin-2 (IL-2) is used in the treatment of solid tumors and hematologic malignancies. Sudden death is a rare complication of IL-2 treatment. METHODS:A patient with lymphoma underwent chemoradiotherapy myeloablation and autologous stem cell transplantation. The stem cells were cultured in IL-2 (6000 IU...

journal_title：Cancer

authors： Truica CI,Hansen CH,Garvin DF,Meehan KR

更新日期：1998-09-15 00:00:00

abstract：:Univariate and multivariate regression methods were used to analyze 17 potential clinical prognostic factors among 138 patients with advanced breast cancer who received Adriamycin-cyclophosphamide combination chemotherapy between 1973 and 1977 at the University of Arizona. Follow-up of patients was through September 1...

journal_title：Cancer

authors： Nash CH 3rd,Jones SE,Moon TE,Davis SL,Salmon SE

更新日期：1980-12-01 00:00:00

abstract：:In recent years, an increased understanding of T-cell-regulatory mechanisms has led to the development of a novel class of immune-checkpoint inhibitors that have robust clinical activity against a broad array of malignancies-even those that historically were not believed to be sensitive to immune therapy. With this, t...

journal_title：Cancer

authors： Salama AK,Postow MA,Salama JK

更新日期：2016-06-01 00:00:00

abstract：:With endometrial adenocarcinoma, several factors, such as stage and histologic grade, are well recognized as having prognostic significance. Other variables, e.g., nuclear grade, probably are also important clinically. A preliminary investigation of the prognostic value of the ploidy, cell cycle kinetics, and sex ster...

journal_title：Cancer

authors： Geisinger KR,Homesley HD,Morgan TM,Kute TE,Marshall RB

更新日期：1986-10-01 00:00:00

abstract：:Data from a hospital-based case-control study between 1985-1990 were used to examine the effects of tobacco, alcohol, asbestos, and other occupational exposures on laryngeal cancer risk in 194 white men with primary cancer of the larynx and 184 age-matched control subjects. A dose-dependent effect for current cigarett...

journal_title：Cancer

authors： Muscat JE,Wynder EL

更新日期：1992-05-01 00:00:00

abstract：BACKGROUND:Obesity is a well known risk factor for the development of endometrial cancer; however, weight alone does not account for all cases. The authors hypothesized that insulin resistance also contributes to an increased risk for endometrial cancer. Adiponectin is a protein secreted by adipose cells and has been s...

journal_title：Cancer

authors： Soliman PT,Wu D,Tortolero-Luna G,Schmeler KM,Slomovitz BM,Bray MS,Gershenson DM,Lu KH

更新日期：2006-06-01 00:00:00

abstract：:In 79 cases of histologically verified anaplastic giant-cell carcinoma, symptoms, treatment, and prognosis were documented. Seventy-eight patients are dead, the mean survival time being 2.5 months. One patient is cured. It was concluded that surgery and/or radiotherapy alone are not sufficient. The results from an add...

journal_title：Cancer

authors： Jereb B,Stjernswärd J,Löwhagen T

更新日期：1975-05-01 00:00:00

abstract：:Clear cell sarcoma is an indolent tumor of uncertain histogenesis. Twenty-seven patients ranging in age from 9 to 57 years (average, 28.5 years) were followed an average of 7.0 years. Females outnumbered males by 2 to 1. Distal extremity locations predominated. At presentation, the tumor was localized in 21 patients, ...

journal_title：Cancer

authors： Eckardt JJ,Pritchard DJ,Soule EH

更新日期：1983-10-15 00:00:00

abstract：:Seventeen patients were given DTIC, 200 mg/m2/day in five-day courses every four to six weeks. In four patients (stage II) treated on an adjuvant basis, tumor recurrence has been verified in three. Four of the palliatively treated patients were also given DTIC by regional intra-arterial infusion with minimal positive ...

journal_title：Cancer

authors： Jönsson PE,Agrup G,Arnbjörnsson E,Hafström L,Rorsman H

更新日期：1980-01-15 00:00:00

abstract：:Biologicals and biological response modifiers (BRMs) represent a new class of agents for cancer therapy. Historically, there have been many attempts to stimulate the immune response with nonspecific immunomodulators in the form of bacterial extracts, viruses, and chemicals. Although these approaches have occasionally ...

journal_title：Cancer

authors： Oldham RK,Thurman GB,Talmadge JE,Stevenson HC,Foon KA

更新日期：1984-12-01 00:00:00

abstract：BACKGROUND:Primary malignant splenic neoplasms are rare tumors. Apart from involvement of the spleen by malignant lymphoma, hemangiosarcoma is the most common form of primary malignant neoplasm in the spleen. The diagnosis often is made at autopsy or after spontaneous splenic rupture. The prognosis is usually poor, and...

journal_title：Cancer

authors： Søndenaa K,Heikkilä R,Nysted A,Søreide JA,Odegaard H,Pollard ML,Holter J

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND:The Akt/mammalian target of rapamycin (mTOR) pathway mediates cell survival and proliferation and contributes to tumor progression. Soft tissue leiomyosarcoma continues to show poor prognosis, and little is known about its mechanisms of tumor progression. Here the authors investigated the significance of act...

journal_title：Cancer

authors： Setsu N,Yamamoto H,Kohashi K,Endo M,Matsuda S,Yokoyama R,Nishiyama K,Iwamoto Y,Dobashi Y,Oda Y

更新日期：2012-03-15 00:00:00

abstract：:The body composition of 23 patients with cachexia resulting from malignant or benign inflammatory disease was studied. Skinfold thickness and radioisotope tracer measurements enabled us to estimate total body fat, lean body mass, the ratio of fat loss to lean body loss, erythrocyte and plasma volumes, total body water...

journal_title：Cancer

authors： Watson WS,Sammon AM

更新日期：1980-11-01 00:00:00

abstract：:Testis cancer and ichthyosis are both relatively rare diseases. Hence the finding of six individuals with both these conditions in a small population with testicular cancer is highly conspicuous and indicates some kind of connection among such persons. Despite the identical clinical appearances of their ichthyoses, th...

journal_title：Cancer

authors： Lykkesfeldt G,Bennett P,Lykkesfeldt AE,Micic S,Rørth M,Skakkebaek NE,Svenstrup B

更新日期：1991-02-01 00:00:00

abstract：BACKGROUND:The goal of this study was to compare health-related quality of life (HRQL) from diagnosis to 10 years postdiagnosis among breast cancer survivors (BCS) and women without cancer over the same period and to identify BCS subgroups exhibiting different HRQL trajectories. METHODS:Our analysis included 141 BCS a...

journal_title：Cancer

authors： Avis NE,Levine B,Goyal N,Crawford SL,Hess R,Colvin A,Bromberger JT,Greendale GA

更新日期：2020-05-15 00:00:00

abstract：BACKGROUND:A combination regimen comprised of docetaxel, gemcitabine, and granulocyte-colony stimulating factor (G-CSF) was studied in patients with advanced nonsmall cell lung carcinoma (NSCLC) to determine its antitumor efficacy and tolerance. METHODS:Thirty-four patients with advanced measurable NSCLC (3 patients w...

journal_title：Cancer

authors： Hejna M,Kornek GV,Raderer M,Ulrich-Pur H,Fiebiger WC,Marosi L,Schneeweiss B,Greul R,Scheithauer W

更新日期：2000-08-01 00:00:00

abstract：:Of 209 Hodgkin's disease patients treated at least 6 months with a five-drug combination of induction chemotherapy and having a complete remission, four patients developed acute myelogenous leukemia (AML) as a second malignant neoplasm. The overall relative risk for development of AML is 185.0 (P less than 0.05) and t...

journal_title：Cancer

authors： Bartolucci AA,Liu C,Durant JR,Gams RA

更新日期：1983-12-15 00:00:00

abstract：BACKGROUND:Cyclin D1 expression has been reported in a subset of patients with diffuse large B-cell leukemia (DLBCL), but studies have been few and generally small, and they have demonstrated no obvious clinical implications attributable to cyclin D1 expression. METHODS:The authors reviewed 1435 patients who were diag...

journal_title：Cancer

authors： Ok CY,Xu-Monette ZY,Tzankov A,O'Malley DP,Montes-Moreno S,Visco C,Møller MB,Dybkaer K,Orazi A,Zu Y,Bhagat G,Richards KL,Hsi ED,Han van Krieken J,Ponzoni M,Farnen JP,Piris MA,Winter JN,Medeiros LJ,Young KH

更新日期：2014-06-15 00:00:00

abstract：BACKGROUND:The unknown etiology of endometrioid carcinomas of the ovary and the relatively high frequency of a concomitant carcinoma of the endometrium in these patients warrants study of such tumors. The aim of this study was to identify the genetic alterations involved in endometrioid ovarian cancer development, and ...

journal_title：Cancer

authors： Shenson DL,Gallion HH,Powell DE,Pieretti M

更新日期：1995-08-15 00:00:00

abstract：BACKGROUND:Aberrant expression of the facilitative glucose transporter, GLUT1, is found in a wide spectrum of epithelial malignancies. The current study describes an immunohistochemical study of GLUT1 expression in benign, hyperplastic, and malignant endometrial epithelia. METHODS:One hundred sixteen formalin fixed, p...

journal_title：Cancer

authors： Wang BY,Kalir T,Sabo E,Sherman DE,Cohen C,Burstein DE

更新日期：2000-06-15 00:00:00

abstract：BACKGROUND:Patients with human papillomavirus (HPV)-related oropharyngeal cancer (OPC) have improved survival when compared with those with HPV-negative OPC. Unfortunately, the American Joint Committee on Cancer seventh edition (AJCC-7ed) staging system does not account for the prognostic advantage observed with HPV-po...

journal_title：Cancer

authors： Malm IJ,Fan CJ,Yin LX,Li DX,Koch WM,Gourin CG,Pitman KT,Richmon JD,Westra WH,Kang H,Quon H,Eisele DW,Fakhry C

更新日期：2017-05-15 00:00:00

abstract：:Forty-nine specimens of carcinoma of the breast were analyzed for estrogen receptor content using the sucrose gradient method and a histochemical method using a conjugate of estradiol (6-BSA-Fluor-CMO-17 beta-estradiol). The specimens analyzed by the histochemical method were graded for fluorescent intensity, percenta...

journal_title：Cancer

authors： Panko WB,Mattioli CA,Wheeler TM

更新日期：1982-05-15 00:00:00

abstract：:Epithelioid sarcoma is an uncommon tumor characterized by its appearance in the distal extremities (especially the forearm, wrist, and ankle), the tendency to recur locally, and high probability of spread to regional lymph nodes. Most patients have been treated surgically, and the potential role of radiation therapy a...

journal_title：Cancer

authors： Shimm DS,Suit HD

更新日期：1983-09-15 00:00:00