Effect of ischemic preconditioning on reactive oxygen species-mediated ischemia--reperfusion injury in the isolated perfused rat lung.

abstract：BACKGROUND:Researchers are debating if fecal calprotectin results are useful for infant patients, especially in screening for necrotizing enterocolitis (NEC). Currently, none of the FDA-approved calprotectin assays provide a cut-off for infant patients. We retrospectively analyzed data from a reference laboratory and u...

journal_title：Clinical biochemistry

authors： Goold E,Pearson L,Johnson LM

更新日期：2020-10-01 00:00:00

abstract：:A high pressure liquid chromatographic method for the determination of hydrochlorothiazide in serum has been elaborated and verified in a blood level study in normal individuals given a single oral dose of 50 mg hydrochlorothiazide. Based on 5 ml of serum, the limit of detection of the method is 2 ng/ml. ...

journal_title：Clinical biochemistry

authors： Robinson WT,Cosyns L

更新日期：1978-08-01 00:00:00

abstract：:A spectrophotometric study was carried out for three proteins assays when modification of their serum procedures using bromcresol green, bromcresol purple and biuret reagents were applied to the determinations of total proteins and albumin in cerebrospinal fluids. A novel concentration device wherein the sample itself...

journal_title：Clinical biochemistry

authors： Artiss JD,Thibert RJ,Zak B

更新日期：1981-02-01 00:00:00

abstract：BACKGROUND:Histamine (HA) is a small amine playing an important role in anaphylactic reactions. In order to identify and quantify HA in plasma matrix, different methods have been developed but present several disadvantages. Here, we developed an alternative method using liquid chromatography coupled with an ultra-high ...

journal_title：Clinical biochemistry

authors： Laurichesse M,Gicquel T,Moreau C,Tribut O,Tarte K,Morel I,Bendavid C,Amé-Thomas P

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:A determination of serum Transthyretin (TTR, Prealbumin) level is an objective method of assessing protein catabolic loss of severely ill patients and numerous studies have shown that TTR levels correlate with patient outcomes of non-critically ill patients. We evaluated whether TTR level correlates with the...

journal_title：Clinical biochemistry

authors： Devakonda A,George L,Raoof S,Esan A,Saleh A,Bernstein LH

更新日期：2008-10-01 00:00:00

abstract：OBJECTIVE:Plasma ammonia measurement is greatly influenced by pre-analytical conditions, which may lead to false positives. We wanted to evaluate the prevalence and clinical impact of plasma ammonia false positives in a pediatric population. DESIGN AND METHODS:Over a 28-month period, charts of patients with elevated a...

journal_title：Clinical biochemistry

authors： Maranda B,Cousineau J,Allard P,Lambert M

更新日期：2007-05-01 00:00:00

abstract：OBJECTIVES:In the process of obtaining a driver's license, a healthy 28year old man presented increased levels of disialo-transferrin (TF) (approx. 20%, ref. value<2) by HPLC analysis of TF isoforms (%CDT), while other markers of excessive alcohol consumption (PEth, MCV and γ-GT) were in the normal range. The objective...

journal_title：Clinical biochemistry

authors： Grahn A,Bengtson P,Eklund E,Asin-Cayuela J

更新日期：2016-04-01 00:00:00

abstract：OBJECTIVES:Presence of residual blood is a common problem in cerebrospinal fluid (CSF) diagnostics of ventriculitis. We hypothesised that neutrophil granulocytes in infected, blood-containing CSF lose CD62L expression. Therefore CD62L expression on neutrophils may present a complementary marker to distinguish between p...

journal_title：Clinical biochemistry

authors： Boer K,Vogelsang H,Deufel T,Pfister W,Kiehntopf M

更新日期：2010-11-01 00:00:00

abstract：OBJECTIVE:To develop a tool to assess the clinical accuracy of glucose meter performance using an insulin dosing protocol to assess the frequency and extent of error in insulin dose categories. METHODS:Retrospective comparison of 1815 glucose meter and central laboratory glucose results obtained from 1698 critically i...

journal_title：Clinical biochemistry

authors： Lyon ME,Lyon OAS,Tran NK,DuBois JA,Lyon AW

更新日期：2019-08-01 00:00:00

abstract：OBJECTIVE:To establish a ELISA assay to measure release of type 1-phospholipase A2 propeptide from activated granulocytes. Human type 1-prophospholipase A2 (1-proPLA2) is biosynthesized and stored as inactive zymogen. Activation involves tryptic-like cleavage at the N-terminus, with equimolar release of the heptapeptid...

journal_title：Clinical biochemistry

authors： Rae D,Sumar N,Beechey-Newman N,Gudgeon M,Hermon-Taylor J

更新日期：1995-02-01 00:00:00

abstract：OBJECTIVE:We developed assays for measurement of urinary betaLH and betaFSH under collection and storage conditions typical of non-clinical research settings. DESIGN AND METHODS:IEMAs for free betaLH and total betaFSH were validated by standard methods. Stability of urinary betaLH and betaFSH was tested across freeze-...

journal_title：Clinical biochemistry

authors： Brindle E,Miller RC,Shofer JB,Klein NA,Soules MR,O'Connor KA

更新日期：2006-11-01 00:00:00

abstract：OBJECTIVE:We used single-strand conformational polymorphism (SSCP) to screen for mutations at nucleotides 833 and 919 of the cystathionine beta-synthase (CBS) gene in 13 patients with homocystinuria and 11 of their relatives. METHODS:Exon 8 of genomic DNA was selectively amplified by PCR using primers derived from int...

journal_title：Clinical biochemistry

authors： Tsai MY,Hanson NQ,Bignell MK,Schwichtenberg KA

更新日期：1996-10-01 00:00:00

abstract：:Macro creatine kinase type 2 (MCK-2) is a promising new tumour marker for carcinoma of the colon. We have purified it from tumour tissue, from serum and, for the first time, from normal colonic epithelium and identified it in a tissue culture line of colon cancer cells. The molecular weight of each preparation, regard...

journal_title：Clinical biochemistry

authors： Rogalsky VY,Koven IH,Miller DR,Pollard A

更新日期：1985-12-01 00:00:00

abstract：OBJECTIVES:The aim of the study was to evaluate the concentration of interleukin 12 (IL-12), the activity of phospholipase A(2) (PLA(2)), and platelet-activating factor acetylhydrolase (PAF-AH) in type 1 diabetes (DM1) patients treated with intensive insulin therapy. DESIGN AND METHODS:Studied parameters were measured...

journal_title：Clinical biochemistry

authors： Wegner M,Araszkiewicz A,Pioruńska-Mikołajczak A,Zozulińska-Ziółkiewicz D,Wierusz-Wysocka B,Pioruńska-Stolzmann M

更新日期：2009-11-01 00:00:00

abstract：OBJECTIVES:Living donor kidney transplantation is regarded as beneficial to allograft recipients and not particularly detrimental to the donors. Recently we have documented a reduced glomerular filtration rate (GFR) in living kidney donors (LKDs). Considering kidneys as essential for l-arginine (Arg) metabolism, in the...

journal_title：Clinical biochemistry

authors： Zunić G,Tomić A,Spasić S

更新日期：2013-10-01 00:00:00

abstract：OBJECTIVES:To evaluate the association between plasma lipids and insulin and variation in the genes for apolipoproteins (APO) E (CfoI), B (insertion/deletion), C1 (HpaI), and C3 (C-482T, C3238G) in a population-based Czech Slavonic study. DESIGN AND METHODS:In 131 men and 154 women, polymorphisms were investigated usi...

journal_title：Clinical biochemistry

authors： Hubacek JA,Waterworth DM,Poledne R,Pitha J,Skodová Z,Humphries SE,Talmud PJ

更新日期：2001-03-01 00:00:00

abstract：:The field of miRNA research is evolving at a very fast pace. Since their discovery almost 20years ago, miRNAs have proven to be of tremendous importance to normal physiological homeostasis as well as to the pathogenesis of major diseases such as cancer. Recent advances describe a key contribution for miRNAs in a wide ...

journal_title：Clinical biochemistry

authors： Tétreault N,De Guire V

更新日期：2013-07-01 00:00:00

abstract：:We report a sensitive and specific method for the determination of AY-25,712 concentrations in rat, dog and human serum by liquid chromatography with UV detection. The detection limit is 25 ng/mL, based on 2 mL of serum or plasma. The method has been validated in human volunteers receiving single oral doses of AY-25,7...

journal_title：Clinical biochemistry

authors： Gonzalez R,Thibeault D

更新日期：1983-08-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to investigate the diagnostic utility of plasma neutrophil gelatinase-associated lipocalin (NGAL) as an early objective biomarker to predict acute kidney injury (AKI) in critically ill patients with suspected sepsis, for whom procalcitonin (PCT) was used for the diagnosis and stagin...

journal_title：Clinical biochemistry

authors： Kim H,Hur M,Cruz DN,Moon HW,Yun YM

更新日期：2013-10-01 00:00:00

abstract：:Epidemiological evidence suggests that the ratio HDL-cholesterol (HDL-C)/total cholesterol (TC) or apolipoprotein A1 (apo A1)/apolipoprotein B (apo B) are good indicators of coronary heart disease risk. In investigating the distribution of these ratios in the typical population served by our routine laboratory, we ana...

journal_title：Clinical biochemistry

authors： Kuyl JM,Mendelsohn D

更新日期：1992-10-01 00:00:00

abstract：OBJECTIVE:Quantitative sweat production and -ionic composition in Essential Hyperhidrosis (EH), and the effects of T2-T3 thoracoscopic sympathicolysis (TS) hereon, are unknown. Standardised pilocarpine iontophoresis sweat tests were performed before and after TS in order to study these issues. DESIGN AND METHODS:Piloc...

journal_title：Clinical biochemistry

authors： Noppen M,Sevens C,Vincken WG

更新日期：1997-03-01 00:00:00

abstract：:Biobanking is a new and very dynamic field. To achieve long term financial sustainability of biobank infrastructures we propose that a new focus is needed on activities, products and services provided by the biobank that relate to the external stakeholder: biobanking 3.0. Earlier stages of biobanking are biobanking 1....

journal_title：Clinical biochemistry

authors： Simeon-Dubach D,Watson P

更新日期：2014-03-01 00:00:00

abstract：OBJECTIVE:To confirm that the naproxen metabolite O-desmethylnaproxen interferes with the Jendrassik and Grof method for total bilirubin and was a possible cause of spurious hyperbilirubinemia in a case of naproxen overdose. DESIGN AND METHODS:Plasma was spiked with naproxen or O-desmethylnaproxen before total and dir...

journal_title：Clinical biochemistry

authors： Al Riyami N,Zimmerman AC,Rosenberg FM,Holmes DT

更新日期：2009-01-01 00:00:00

abstract：:An early diagnosis is crucial for effective triage and management of patients with suspected acute myocardial infarction (AMI). Although troponin testing is the cornerstone of diagnosis, the sensitivity of this biomarker is still suboptimal at patient admission. The heart-type fatty acid binding protein (H-FABP) is an...

journal_title：Clinical biochemistry

authors： Lippi G,Mattiuzzi C,Cervellin G

更新日期：2013-01-01 00:00:00

abstract：OBJECTIVES:Breast cancer is the most common malignancy among Egyptian women. The aim of this study is to evaluate the role of both telomerase and TPS estimation in assessment of breast cancer. METHODS:The study included 40 patients with breast cancer, and 20 patients with benign breast diseases. Telomerase activity in...

journal_title：Clinical biochemistry

authors： Kassim SK,Fawzy H,El Rassad MM,Khalil FK,Khalifa A

更新日期：2001-09-01 00:00:00

abstract：OBJECTIVES:To evaluate the results of oxygen consumption measurement in lymphocytes for the diagnosis and treatment monitoring of pediatric patients with oxidative phosphorylation diseases. DESIGN AND METHODS:Twenty-four children with an oxidative phosphorylation disease were studied. Results were compared with those ...

journal_title：Clinical biochemistry

authors： Artuch R,Colomé C,Playán A,Alcaine MJ,Briones P,Montoya J,Vilaseca MA,Pineda M

更新日期：2000-08-01 00:00:00

abstract：OBJECTIVES:Familial hypercholesterolemia (FH) is characterized by increased oxidative stress (OS) levels. In the postprandial state, lipids and lipoproteins modulate OS status through their impact on pro-oxidant and antioxidant mechanisms. The objective of this study was to evaluate in patients with FH the response to ...

journal_title：Clinical biochemistry

authors： Cortes R,Martinez-Hervas S,Ivorra C,De Marco G,Gonzalez-Albert V,Rojo-Martínez G,Saez G,Carmena R,Ascaso JF,Real JT,Chaves FJ

更新日期：2014-12-01 00:00:00

abstract：OBJECTIVES:The Golgi SNAP receptor complex member 2 (GOSR2) gene is a Golgi-associated soluble factor attachment receptor (SNARE) protein involved in intra-Golgi protein trafficking on chromosome 17q21, which is the hypertension linkage peak on the human chromosome. The aim of the present study was to assess the associ...

journal_title：Clinical biochemistry

authors： Pan S,Nakayama T,Sato N,Izumi Y,Soma M,Aoi N,Ma Y

更新日期：2013-06-01 00:00:00

abstract：OBJECTIVES:Plasma retinol-binding protein (RBP) has been linked to insulin resistance and cardiovascular risk, yet little is know of its natural variation in plasma. We examined this in normal subjects and compared plasma levels and variability in lean subjects and subjects with the metabolic syndrome. METHODS:We esta...

journal_title：Clinical biochemistry

authors： Lewis JG,Shand BI,Frampton CM,Elder PA

更新日期：2007-07-01 00:00:00

abstract：OBJECTIVE:To quantitatively summarize the association between tumour necrosis factor alpha (TNF-alpha) gene polymorphisms and Graves' disease. DESIGN AND METHODS:Relevant studies were identified from the following electronic databases: Cochrane Library, MEDLINE, EMBASE and Chinese Bio-medicine Database. A meta-analysi...

journal_title：Clinical biochemistry

authors： Li N,Zhou Z,Liu X,Liu Y,Zhang J,Du L,Wei M,Chen X

更新日期：2008-07-01 00:00:00