Abstract:
:Epidemiological evidence suggests that the ratio HDL-cholesterol (HDL-C)/total cholesterol (TC) or apolipoprotein A1 (apo A1)/apolipoprotein B (apo B) are good indicators of coronary heart disease risk. In investigating the distribution of these ratios in the typical population served by our routine laboratory, we analysed the lipid results of 541 serum samples submitted over a 2-month period for TC, HDL-C, apo A1, and apo B. Good correlation was observed between HDL-C and apo A1 (r = 0.664), and between TC and apo B (r = 0.674). Surprisingly, the correlation between the ratios HDL-C/TC (range: 0.05-0.40) and apo A1/apo B (range: 0.27-3.71) was even higher (r = 0.822). Similar significant correlations were observed in 31 heterozygous and 20 homozygous familial hypercholesterolemic subjects, viz. the correlations between HDL-C/TC (ranges: 0.04-0.24 and 0.02-0.12, respectively) and apo A1/apo B (ranges: 0.47-1.84 and 0.15-1.12, respectively) were r = 0.951 and r = 0.972, respectively.
journal_name
Clin Biochemjournal_title
Clinical biochemistryauthors
Kuyl JM,Mendelsohn Ddoi
10.1016/0009-9120(92)80004-zsubject
Has Abstractpub_date
1992-10-01 00:00:00pages
313-6issue
5eissn
0009-9120issn
1873-2933pii
0009-9120(92)80004-Zjournal_volume
25pub_type
杂志文章abstract::Retrospective analysis of DNA from paraffin-embedded fixed bone marrow biopsy specimens is possible if preceded by amplification of the DNA sequences of interest by the polymerase chain reaction (PCR). These fixed specimens yield degraded DNA that may not be suitable for direct analysis by conventional digestion and h...
journal_title:Clinical biochemistry
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journal_title:Clinical biochemistry
pub_type: 杂志文章,评审
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更新日期:2005-03-01 00:00:00
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更新日期:1978-06-01 00:00:00
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journal_title:Clinical biochemistry
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journal_title:Clinical biochemistry
pub_type: 杂志文章
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更新日期:2016-02-01 00:00:00
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journal_title:Clinical biochemistry
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更新日期:2013-11-01 00:00:00
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journal_title:Clinical biochemistry
pub_type: 杂志文章
doi:10.1016/j.clinbiochem.2009.12.008
更新日期:2010-04-01 00:00:00
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journal_title:Clinical biochemistry
pub_type: 杂志文章,评审
doi:10.1016/j.clinbiochem.2008.02.017
更新日期:2008-06-01 00:00:00
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journal_title:Clinical biochemistry
pub_type: 杂志文章
doi:10.1016/j.clinbiochem.2006.02.012
更新日期:2006-07-01 00:00:00
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journal_title:Clinical biochemistry
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doi:10.1016/j.clinbiochem.2017.07.016
更新日期:2017-12-01 00:00:00
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journal_title:Clinical biochemistry
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doi:10.1016/j.clinbiochem.2010.04.065
更新日期:2010-08-01 00:00:00
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pub_type: 杂志文章
doi:10.1016/s0009-9120(00)00196-x
更新日期:2001-02-01 00:00:00
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journal_title:Clinical biochemistry
pub_type: 杂志文章
doi:10.1016/j.clinbiochem.2011.08.1134
更新日期:2011-11-01 00:00:00
abstract::The investigation of oxidative stress (OS), its mechanisms and connections with human diseases, is a topic of interest with more than 36,000 PubMed citations to date. The OS can be approached either from the perspective of pro-oxidation, either of anti-oxidation, and both can be investigated considering individual che...
journal_title:Clinical biochemistry
pub_type: 杂志文章,评审
doi:10.1016/j.clinbiochem.2016.11.037
更新日期:2017-04-01 00:00:00
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journal_title:Clinical biochemistry
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doi:10.1016/j.clinbiochem.2011.06.004
更新日期:2011-09-01 00:00:00
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pub_type: 杂志文章
doi:10.1016/j.clinbiochem.2004.06.008
更新日期:2004-10-01 00:00:00
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更新日期:2018-03-01 00:00:00
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更新日期:2011-07-01 00:00:00
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journal_title:Clinical biochemistry
pub_type: 杂志文章
doi:10.1016/0009-9120(90)80042-h
更新日期:1990-12-01 00:00:00
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journal_title:Clinical biochemistry
pub_type: 杂志文章
doi:10.1016/j.clinbiochem.2016.10.014
更新日期:2017-02-01 00:00:00
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doi:10.1016/j.clinbiochem.2013.12.011
更新日期:2014-03-01 00:00:00
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journal_title:Clinical biochemistry
pub_type: 杂志文章
doi:10.1016/0009-9120(94)00083-8
更新日期:1995-06-01 00:00:00
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journal_title:Clinical biochemistry
pub_type: 杂志文章
doi:10.1016/j.clinbiochem.2004.05.027
更新日期:2004-09-01 00:00:00
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pub_type: 杂志文章
doi:10.1016/j.clinbiochem.2006.08.014
更新日期:2007-01-01 00:00:00
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journal_title:Clinical biochemistry
pub_type: 杂志文章
doi:10.1016/j.clinbiochem.2007.10.007
更新日期:2008-01-01 00:00:00
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journal_title:Clinical biochemistry
pub_type: 杂志文章,评审
doi:10.1016/j.clinbiochem.2014.01.033
更新日期:2014-06-01 00:00:00
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journal_title:Clinical biochemistry
pub_type: 杂志文章
doi:10.1016/j.clinbiochem.2006.04.018
更新日期:2006-08-01 00:00:00