Hypocomplementemia and membranoproliferative glomeruloneophritis in children.

abstract：:Lipoprotein glomerulopathy (LPG) is a rare hereditary disease characterized by the accumulation of much thrombi material consisting of lipoproteins at the glomerular capillary lumen. Most patients show nephrotic syndrome; nearly half progress to chronic renal failure. Intensive therapy with lipid-lowering agents repor...

journal_title：Clinical and experimental nephrology

authors： Matsunaga A,Furuyama M,Hashimoto T,Toyoda K,Ogino D,Hayasaka K

更新日期：2009-12-01 00:00:00

abstract：BACKGROUND:The post-marketing surveillance of edaravone has reported serious adverse reactions, including renal and hepatic disorders. Renal disorders were the most frequently reported serious/important adverse reactions, which led to the evaluation of their causation by edaravone, their severity, and the recovery of r...

journal_title：Clinical and experimental nephrology

authors： Hishida A

更新日期：2007-12-01 00:00:00

abstract：BACKGROUND:It has been recently reported that peroxisome proliferator-activated receptors (PPARs)gamma exist in various tissues and that they exibit anti-inflammatory effects. METHODS:We investigated the effects of PPARgamma activators on the development of crescentic glomerulonephritis. Crescentic glomerulonephritis ...

journal_title：Clinical and experimental nephrology

authors： Haraguchi K,Shimura H,Onaya T

更新日期：2003-03-01 00:00:00

abstract：BACKGROUND:Although a high prevalence of macrovascular disease (MVD) has been reported in patients with stage 3 chronic kidney disease (CKD), few studies have reported its risk with respect to the underlying cause of kidney disease. This study investigated the prevalence of MVD in type 2 diabetic patients with CKD stra...

journal_title：Clinical and experimental nephrology

authors： Tanaka K,Hara S,Kushiyama A,Ubara Y,Yoshida Y,Mizuiri S,Aikawa A,Kawatzu S

更新日期：2011-06-01 00:00:00

abstract：BACKGROUND:The number of elderly dialysis patients in Japan is dramatically increasing. Receiving therapy with better satisfaction through home care is one of the important factors in their daily lives. Thus, the quality of life of elderly patients on hemodialysis (HD) or peritoneal dialysis (PD) was evaluated. METHOD...

journal_title：Clinical and experimental nephrology

authors： Saka Y,Naruse T,Tawada N,Tokomoto M,Noda Y,Taniguchi Y,Nagahara Y,Yamashita R,Karasawa M,Watanabe Y,Ito Y

更新日期：2017-10-01 00:00:00

abstract：BACKGROUND:Chronic kidney disease (CKD) is a major global problem and is also associated with a decreased health-related quality of life (HRQOL). The aim of this study was to evaluate measured HRQOL based on the new CKD classification including proteinuria stage, and the effect of measured HRQOL on CKD progression and ...

journal_title：Clinical and experimental nephrology

authors： Okubo R,Kai H,Kondo M,Saito C,Yoh K,Morito N,Usui J,Yamagata K

更新日期：2014-10-01 00:00:00

abstract：:C1q nephropathy, first proposed by Jennette and Hipp [Am J Clin Pathol 83:415-420, 1985; Am J Kidney Dis 6:103-110, 1985], was described as a distinct glomerular disease entity characterized by extensive mesangial deposition of C1q, with associated mesangial immune complexes, and the absence of any clinical and labora...

journal_title：Clinical and experimental nephrology

authors： Mii A,Shimizu A,Masuda Y,Fujita E,Aki K,Ishizaki M,Sato S,Griesemer A,Fukuda Y

更新日期：2009-08-01 00:00:00

abstract：BACKGROUND/AIMS:Vascular access dysfunction caused by stenosis is a major complication for hemodialysis (HD) patients. However, physiopathology of late arteriovenous fistula (AVF) stenosis is still under investigation. The aim of the present study was to evaluate the association between plasma soluble EPCR (sEPCR) with...

journal_title：Clinical and experimental nephrology

authors： Bilgic MA,Yilmaz H,Bozkurt A,Celik HT,Bilgic IC,Gurel OM,Kirbas I,Bavbek N,Akcay A

更新日期：2015-02-01 00:00:00

abstract：:A 68-year-old man with a 30-year history of essential thrombocytosis developed nephrotic syndrome. Renal biopsy showed massive deposits of Congo red-negative periodic acid Schiff (PAS)-positive substance in the mesangium and capillary wall that was positive for IgG. Electron microscopic examination revealed 10- to 20-...

journal_title：Clinical and experimental nephrology

authors： Asaba K,Tojo A,Onozato ML,Mimura N,Kido M,Goto A,Endo H,Fujita T

更新日期：2003-12-01 00:00:00

abstract：:A 69-year-old Caucasian man was admitted to our hospital because of myocardial infarction. A central venous catheter (CVC) for infusive therapy was inserted. After two weeks he developed fever, purpura, and knee arthralgia. Hemoculture yielded methicillin-sensitive Staphylococcus aureus. Subsequently, oliguric renal f...

journal_title：Clinical and experimental nephrology

authors： Uggeri S,Fabbian F,Catizone L

更新日期：2008-06-01 00:00:00

abstract：BACKGROUND:Dotinurad, a novel selective urate reabsorption inhibitor, exerts a serum uric acid-lowering effect by selectively inhibiting urate transporter 1 (URAT1) in patients with hyperuricemia. It is generally known that the progression of renal dysfunction is associated with a reduction in the serum uric acid-lower...

journal_title：Clinical and experimental nephrology

authors： Fukase H,Okui D,Sasaki T,Fushimi M,Ohashi T,Hosoya T

更新日期：2020-03-01 00:00:00

abstract：:Unique renal histopathological appearances, consisting of podocytic infolding and microstructures in the glomerular basement membrane (GBM) were identified in the renal biopsies from three patients with collagen diseases such as systemic lupus erythematosus (lupus nephritis, class II) and Sjögren's syndrome. In each c...

journal_title：Clinical and experimental nephrology

authors： Sugiyama H,Maruyama M,Morinaga H,Inoue T,Takiue K,Kikumoto Y,Kinomura M,Sada KE,Akagi S,Kitamura S,Maeshima Y,Makino H

更新日期：2008-12-01 00:00:00

abstract：BACKGROUND:Although neutrophil-to-lymphocyte ratio (NLR) is closely associated with pneumonia in the general population, its relationship is unclear in peritoneal dialysis (PD) patients. METHODS:This is a cohort study consisting of 739 PD patients and dividing into two groups. Kaplan-Meier curves were applied to obser...

journal_title：Clinical and experimental nephrology

authors： Zhang Y,Lai X,Chen Q,Zhan X,Long H,Peng F,Zhang F,Feng X,Zhou Q,Wu X,Liu L,Wang Z,ETNA.,Peng X,Hu K,Wang D,Guo G,Zeng Y,Wen Y,Liang J

更新日期：2020-09-01 00:00:00

abstract：:A 78-year old woman with complicating solitary kidney had nephrotic syndrome. Renal biopsy specimens showed focal segmental glomerulosclerosis (FSGS). First, the patient was treated with angiotensin receptor blocker (ARB) and angiotensin converting enzyme inhibitor (ACEI). Proteinuria decreased from 10 to 6 g/day, but...

journal_title：Clinical and experimental nephrology

authors： Oshiro Y,Umena S,Noda M

更新日期：2009-02-01 00:00:00

abstract：BACKGROUND:Two randomized, double-blind, placebo-controlled trials (EPPIC-1 and EPPIC-2) investigated the efficacy and safety of AST-120, an oral spherical carbon adsorbent, in adults with chronic kidney disease (CKD). While the benefit of adding AST-120 to standard therapy was not supported by these trials, we perform...

journal_title：Clinical and experimental nephrology

authors： Schulman G,Berl T,Beck GJ,Remuzzi G,Ritz E,Shimizu M,Kikuchi M,Shobu Y

更新日期：2018-04-01 00:00:00

abstract：BACKGROUND:Previous studies reported that children with neural tube defects, but without any history of intrinsic renal diseases, have small kidneys when compared with age-matched standard renal growth. The aim of this study was to investigate the possible causes of small renal size in children with spina bifida by com...

journal_title：Clinical and experimental nephrology

authors： Montaldo P,Montaldo L,Iossa AC,Cennamo M,Caredda E,Del Gado R

更新日期：2014-02-01 00:00:00

abstract：BACKGROUND:The appropriate blood pressure target to prevent end-stage renal disease (ESRD) is controversial. METHODS:We examined the association between systolic blood pressure (SBP) changes and ESRD incidence in 69,575 participants from the Okinawa general population aged ≥ 20 years who underwent health check-ups in ...

journal_title：Clinical and experimental nephrology

authors： Usui T,Iseki C,Iseki K,Kawakami K,Nangaku M

更新日期：2019-11-01 00:00:00

abstract：BACKGROUND:Data about the clinical outcomes of ACS patients with advanced renal dysfunction (estimated glomerular filtration rate < 30 mL/min/1.73 m2) following percutaneous coronary intervention (PCI) are limited. METHODS:We examined the data obtained from 194 ACS patients with non-dialysis advanced renal dysfunction...

journal_title：Clinical and experimental nephrology

authors： Uemura Y,Ishikawa S,Takemoto K,Negishi Y,Tanaka A,Takagi K,Yoshioka N,Umemoto N,Inoue Y,Morishima I,Shibata N,Asano H,Ishii H,Watarai M,Murohara T,N-registry investigators.

更新日期：2020-04-01 00:00:00

abstract：:The manifestation of diabetic nephropathy may be a consequence of the actions of certain cytokines and growth factors. Prominent among them is transforming growth factor-β (TGF-β), which promotes renal cell hypertrophy and stimulates extracellular matrix accumulation, the two hallmarks of diabetic renal disease. In ex...

journal_title：Clinical and experimental nephrology

authors： Ziyadeh FN,Isono M,Chen S

更新日期：2002-09-01 00:00:00

abstract：:A 69-year-old woman presented with unusual electron microscopic findings. The patient was admitted to ascertain the cause of her persistent proteinuria, and kidney biopsy was performed. While light microscopic findings and immunofluorescence study suggested membranous nephropathy, electron microscopic study showed mic...

journal_title：Clinical and experimental nephrology

authors： Nomura S,Inoue-Kiyohara M,Oosugi K,Ishikawa E,Obe T,Horiki T,Ito M

更新日期：2008-12-01 00:00:00

abstract：BACKGROUND:Hematuria is the first manifestation of urinary abnormality in immunoglobulin A nephropathy (IgAN). Hematuria has recently been reported as a risk factor for deterioration of renal function; however, its cause remains unknown. METHODS:We analyzed the surface marker of peripheral blood mononuclear cells befo...

journal_title：Clinical and experimental nephrology

authors： Iwatani H,Nagasawa Y,Yamamoto R,Iio K,Mizui M,Horii A,Kitahara T,Inohara H,Kumanogoh A,Imai E,Rakugi H,Isaka Y

更新日期：2015-04-01 00:00:00

abstract：:A 57-year-old woman presented with fever and cellulitis of the right leg. Urinalysis and kidney function were normal on admission. Cellulitis remitted but fever persisted for six weeks. X-ray imaging, cultures, serological assays for viruses and autoimmunity did not reveal the cause of fever. Unexpectedly anti-Scl 70 ...

journal_title：Clinical and experimental nephrology

authors： Vega Stieb J,Goecke Saavedra H,Méndez Olivieri G

更新日期：2008-10-01 00:00:00

abstract：BACKGROUND:Autosomal dominant polycystic kidney disease (ADPKD), one of the most common hereditary kidney diseases, causes gradual growth of cysts in the kidneys, leading to renal failure. Owing to the advanced technology of next-generation sequencing (NGS), genetic analyses of the causative genes PKD1 and PKD2 have be...

journal_title：Clinical and experimental nephrology

authors： Mochizuki T,Teraoka A,Akagawa H,Makabe S,Akihisa T,Sato M,Kataoka H,Mitobe M,Furukawa T,Tsuchiya K,Nitta K

更新日期：2019-08-01 00:00:00

abstract：:Posterior reversible encephalopathy syndrome (PRES) is a rare complication of nephrotic syndrome and corticosteroid therapy. Here, we discuss an 18 year old man with type 1 membranoproliferative glomerulonephritis (MPGN) secondary to hepatitis B infection who developed posterior leukoencephalopathy while on therapy wi...

journal_title：Clinical and experimental nephrology

authors： Sathyanarayanan V,Razak A,Narayan G,Prabhu M,Ramachandran B,Ranjini K,Vidya M,Joshi K

更新日期：2010-12-01 00:00:00

abstract：:Idiopathic nephrotic syndrome is the most common chronic glomerular disease in children. At least 20 % of children with this syndrome show frequent relapses and/or steroid dependence during or after immunosuppressive therapies, a condition defined as complicated frequently relapsing/steroid-dependent nephrotic syndrom...

journal_title：Clinical and experimental nephrology

authors： Iijima K,Sako M,Nozu K

更新日期：2017-04-01 00:00:00

abstract：BACKGROUND:The aim of this study was to evaluate the renal preservation effect of ubiquinol, the reduced form of coenzyme Q10 (CoQ10). METHODS:Three-week-old heminephrectomized male Sprague-Dawley rats were divided into three groups (10 animals each): diet with normal (0.3%) salt, high (8%) salt, and high salt plus 60...

journal_title：Clinical and experimental nephrology

authors： Ishikawa A,Kawarazaki H,Ando K,Fujita M,Fujita T,Homma Y

更新日期：2011-02-01 00:00:00

abstract：BACKGROUND:Depression is common in chronic kidney disease (CKD) patients and associated with significant increase in morbidity and mortality. In recent years, a relationship between vitamin D deficiency and depression has been shown. The aim of this study is to investigate the relationship between 25-hydroxy (OH) vitam...

journal_title：Clinical and experimental nephrology

authors： Yavuz YC,Biyik Z,Ozkul D,Abusoglu S,Eryavuz D,Dag M,Korez MK,Guney I,Altintepe L

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:The suitable methods evaluating glomerular filtration rate (GFR) have not been established in patients undergoing radical nephrectomy (RN) or radical nephroureterectomy (RNU) due to urological malignancies in Japan as well as worldwide. METHODS:We examined the relationship between creatinine clearance-based...

journal_title：Clinical and experimental nephrology

authors： Niwa N,Yoshida T,Mizuno R,Kikuchi E,Miyajima A,Hayashi M,Oya M

更新日期：2018-10-01 00:00:00

abstract：:A 33-year-old woman was transferred to our hospital with a 5-month history of taking Chinese herbal medicine containing aristolochic acid. She presented with metabolic acidosis, severe anemia, hypophosphatemia and uric aciduria, and generalized aminoaciduria and glycosuria, features which were consistent with the clin...

journal_title：Clinical and experimental nephrology

authors： Kazama I,Matsubara M,Michimata M,Suzuki M,Hatano R,Sato H,Ito S

更新日期：2004-09-01 00:00:00

abstract：:Inflammatory pseudotumour (IPT) is a rare disease of unknown cause that most commonly involves the lung but can occur in almost any site in the body. Occurrence in the kidneys is very rare and bilateral renal involvement even rarer. There are 34 previously reported cases in the English-language medical literature betw...

journal_title：Clinical and experimental nephrology

authors： Li JY,Yong TY,Coleman M,Astill D,Passaris G,Juneja R,Siddins M,Barbara JA

更新日期：2010-04-01 00:00:00