Abstract:
:Since first reported in Europe in the early 1980s, extended-spectrum beta-lactamases (ESBLs) have spread worldwide. When producing these broad-spectrum plasmid-encoded enzymes, organisms become highly effective at inactivating penicillins, most cephalosporins, and aztreonam. Mainly produced by Klebsiella spp, ESBLs have been isolated worldwide in different species, most of them belonging to the Enterobacteriaceae. ESBL-producing bacteria can appear as in vitro susceptible to beta-lactams by conventional laboratory methods, making the laboratory diagnosis problematic. Once detected, all beta-lactams except carbapenem and beta-lactamase inhibitor compounds should be reported as resistant. In addition, organisms harboring ESBLs are frequently resistant to other antibiotic classes, such as fluoroquinolones and aminoglycosides. Because of the very limited remaining alternatives for treatment and ESBLs significant prevalence worldwide, infection control remains the best way to deal with this bacterial resistance mechanism.
journal_name
Am J Infect Controljournal_title
American journal of infection controlauthors
Colodner Rdoi
10.1016/j.ajic.2004.07.010subject
Has Abstractpub_date
2005-03-01 00:00:00pages
104-7issue
2eissn
0196-6553issn
1527-3296pii
S0196655304005681journal_volume
33pub_type
杂志文章,评审abstract:BACKGROUND:There are no guidelines or quality benchmarks specific to ureteroscope reprocessing, and patient injuries and infections have been linked to ureteroscopes. This prospective study evaluated ureteroscope reprocessing effectiveness. METHODS:Reprocessing practices at 2 institutions were assessed. Microbial cult...
journal_title:American journal of infection control
pub_type: 杂志文章
doi:10.1016/j.ajic.2017.03.016
更新日期:2017-08-01 00:00:00
abstract::Growing evidence reveals the importance of improving safety culture in efforts to eliminate health care-associated infections. This multisite, cross-sectional survey examined the association between professional role and health care experience on infection prevention safety culture at 5 hospitals. The findings suggest...
journal_title:American journal of infection control
pub_type: 杂志文章,多中心研究
doi:10.1016/j.ajic.2012.09.006
更新日期:2013-07-01 00:00:00
abstract::The failure of the 1982-1983 influenza vaccine to protect elderly NHCU residents from clinical infection with influenza A/Philippines/2/82 resulted primarily from antigenic drift of the epidemic strain, inasmuch as the attack rates in the vaccinated and nonvaccinated patients were not significantly different. This exp...
journal_title:American journal of infection control
pub_type: 杂志文章
doi:10.1016/0196-6553(84)90005-1
更新日期:1984-12-01 00:00:00
abstract:BACKGROUND:Clostridium difficile is the usual and most important cause of antibiotic-associated pseudomembranous enterocolitis. The source of nosocomial acquisition of the organism in nonepidemic settings has not been determined. METHODS:Epidemiologic and microbiologic studies were conducted in a community-teaching ho...
journal_title:American journal of infection control
pub_type: 杂志文章
doi:10.1016/0196-6553(94)90070-1
更新日期:1994-08-01 00:00:00
abstract:BACKGROUND:Influenza causes mortality and morbidity in the frail elderly population. Influenza prevention and mitigation models need to be developed for this population. METHODS:An observational study at a Program for All-Inclusive Care for the Elderly (PACE) during years 1999-2004. Participants were frail elderly adu...
journal_title:American journal of infection control
pub_type: 杂志文章
doi:10.1016/j.ajic.2005.02.001
更新日期:2005-05-01 00:00:00
abstract::The virucidal activity of 2 hand rubs proposed by the World Health Organization was studied in a quantitative suspension test for chemical disinfectants and antiseptics in human medicine (EN 14476). These formulations are recommended if no hand rubs with declared microbiological activity are available in health care s...
journal_title:American journal of infection control
pub_type: 杂志文章
doi:10.1016/j.ajic.2009.07.009
更新日期:2010-02-01 00:00:00
abstract:BACKGROUND:Optimal usability is crucial in providing protection for health care workers who are exposed to severe acute respiratory syndrome day and night while taking care of patients with the virus. No research study has yet tested the usability of personal protective clothing (PPC). METHOD:The study was carried out...
journal_title:American journal of infection control
pub_type: 杂志文章
doi:10.1016/j.ajic.2003.08.004
更新日期:2004-04-01 00:00:00
abstract::Vancomycin-resistant Staphylococcus aureus (VRSA) and methicillin-resistant S aureus (MRSA) strains were examined in hospital effluents. Most S aureus strains are resistant to methicillin (MRSA), followed by tetracycline. Approximately 15% of MRSA strains are also resistant to vancomycin (VRSA). All VRSA strains devel...
journal_title:American journal of infection control
pub_type: 杂志文章
doi:10.1016/j.ajic.2015.08.015
更新日期:2015-12-01 00:00:00
abstract:BACKGROUND:Control chart methodology has been widely touted for monitoring and improving quality in the health care setting. P charts and U charts are frequently recommended for rate and ratio statistics, but their practical value in infection control may be limited because they (1) are not risk-adjusted, and (2) perfo...
journal_title:American journal of infection control
pub_type: 杂志文章
doi:10.1067/mic.2000.109883
更新日期:2000-12-01 00:00:00
abstract::The Healthcare Infection Control Practices Advisory Committee released hand hygiene guidelines recommending that hospitals educate personnel to increase compliance with hand hygiene. However, few educational tools are available to assist hospitals in this effort. Eight hospitals were recruited to implement hand hygien...
journal_title:American journal of infection control
pub_type: 杂志文章,多中心研究
doi:10.1016/j.ajic.2005.06.010
更新日期:2006-04-01 00:00:00
abstract:BACKGROUND:The prevalence of healthcare associated infection (HAI) is generally higher in countries with limited resources than developed countries. To address the high prevalence of HAI, Turkish Ministry of Health introduced a national infection control program in 2005. METHODS:Device associated (DA)-HAIs routinely s...
journal_title:American journal of infection control
pub_type: 杂志文章
doi:10.1016/j.ajic.2020.12.013
更新日期:2020-12-25 00:00:00
abstract:BACKGROUND:Chlorhexidine gluconate (CHG) and povidone iodine (PI) are rarely used concurrently despite a lack of evidence regarding functional incompatibility of these agents. METHODS:CHG and PI, alone and combined, were evaluated against Staphylococcus aureus (methicillin-susceptible S aureus [MSSA] and methicillin-r...
journal_title:American journal of infection control
pub_type: 杂志文章
doi:10.1016/j.ajic.2010.06.022
更新日期:2010-12-01 00:00:00
abstract:BACKGROUND:Infection preventionists (IPs) play key roles in preventing health care-associated infections and ensuring quality of care. To develop strategies to support comprehensive infection prevention practice, it is critical to understand key aspects of their practice. METHODS:A task force of expert IPs, staff repr...
journal_title:American journal of infection control
pub_type: 杂志文章
doi:10.1016/j.ajic.2016.12.012
更新日期:2017-06-01 00:00:00
abstract:BACKGROUND:Methicillin-resistant Staphylococcus aureus (MRSA) is a pathogenic S aureus strain characteristic associated with increased patient morbidity and mortality. The health care system needs to understand MRSA transmissibility in all settings to improve basic preventive measures to generate sustained reductions i...
journal_title:American journal of infection control
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.ajic.2017.11.002
更新日期:2018-05-01 00:00:00
abstract:BACKGROUND:Asymptomatic bacteriuria is often treated with antimicrobials despite no benefit to patients, contributing to antimicrobial resistance and costs. Identifying knowledge deficits may improve physician training and antimicrobial stewardship efforts. We surveyed internal medicine and medicine-pediatrics resident...
journal_title:American journal of infection control
pub_type: 杂志文章
doi:10.1016/j.ajic.2013.01.020
更新日期:2013-10-01 00:00:00
abstract::Central line-associated bloodstream infection (CLABSI) event data reported to the National Healthcare Safety Network from 2014, the first year of required use of the mucosal barrier injury laboratory-confirmed bloodstream infection (MBI-LCBI) definition, were analyzed to assess the impact of removing MBI-LCBI events f...
journal_title:American journal of infection control
pub_type: 杂志文章
doi:10.1016/j.ajic.2016.10.015
更新日期:2017-03-01 00:00:00
abstract:BACKGROUND:Thermally injured patients are at high risk for infections, including hospital acquired infections (HAIs). We modeled a twice-daily chlorhexidine gluconate (CHG) bath protocol aimed at decreasing HAIs. METHODS:Bathing with a 0.9% CHG solution in sterile water was provided twice daily as part of routine care...
journal_title:American journal of infection control
pub_type: 杂志文章
doi:10.1016/j.ajic.2013.08.015
更新日期:2014-02-01 00:00:00
abstract:BACKGROUND:Staphylococcus aureus (SA) is a common bacterial pathogen in skin and skin structure infections (SSSIs). Limited data exist on hospital treatment patterns and costs for SA-SSSIs. METHODS:This retrospective analysis examined the lengths of stay, treatment patterns, and costs of hospitalized patients with an ...
journal_title:American journal of infection control
pub_type: 杂志文章
doi:10.1016/j.ajic.2009.04.287
更新日期:2010-02-01 00:00:00
abstract:BACKGROUND:Hospital-acquired infection, including catheter-associated urinary tract infection (CAUTI), is common. Although CAUTI is usually preventable, hospital units may struggle to reduce CAUTI rates. The CAUTI guide to patient safety (GPS) was developed to assess a unit's CAUTI prevention activities. Our aim was to...
journal_title:American journal of infection control
pub_type: 杂志文章
doi:10.1016/j.ajic.2016.03.051
更新日期:2016-10-01 00:00:00
abstract::We analyzed a set of clinical parameters using Cox proportional hazard regressions to yield significant factors associated with the development of ventilator-associated events. In our study, intubation site, certain comorbidities, morphine, prednisone, and nutrition emerged as factors. Additionally, we presented poten...
journal_title:American journal of infection control
pub_type: 杂志文章
doi:10.1016/j.ajic.2018.09.024
更新日期:2019-04-01 00:00:00
abstract:BACKGROUND:Meningococcal disease remains a major concern in populations living under crowded conditions. Following the 1995 report of several cases of meningococcal disease in Israeli soldiers, the Department of Epidemiology of the Army Health Branch, Israel Defense Forces (IDF) adopted an immunization policy for all r...
journal_title:American journal of infection control
pub_type: 杂志文章
doi:10.1016/j.ajic.2009.04.290
更新日期:2010-02-01 00:00:00
abstract:BACKGROUND:It is generally recognized that the health care system does not have adequate isolation capacity to meet the surge in demand during a major outbreak of airborne infectious disease. Alternatives to engineered isolation rooms undoubtedly will be required as surge isolation requirements exceed the available res...
journal_title:American journal of infection control
pub_type: 杂志文章
doi:10.1016/j.ajic.2008.05.011
更新日期:2009-03-01 00:00:00
abstract:BACKGROUND:There is a large and growing body of evidence that methicillin-resistant Staphylococcus aureus (MRSA) screening programs are cost effective, but such screening represents a significant cost burden for hospitals. This study investigates the clinical, patient experience and cost impacts of performing active su...
journal_title:American journal of infection control
pub_type: 杂志文章
doi:10.1016/j.ajic.2014.07.011
更新日期:2014-10-01 00:00:00
abstract:OBJECTIVE:We sought to determine the cause and mode of transmission of a cluster of bloodstream infections as a result of Klebsiella pneumoniae. DESIGN AND SETTING:We conducted a prospective cohort study in a neonatal intensive care department from May 1999 to December 2000. METHODS:We performed surveillance of nosoc...
journal_title:American journal of infection control
pub_type: 杂志文章
doi:10.1067/mic.2003.70
更新日期:2003-11-01 00:00:00
abstract::This study investigated the presence of adenovirus and norovirus on ward surfaces using real-time polymerase chain reaction (PCR) to assist in the development of evidence-based infection control policy. Screening was carried out weekly for 6 months in the common areas of 2 pediatric wards. Additionally, a one-off scre...
journal_title:American journal of infection control
pub_type: 杂志文章
doi:10.1016/j.ajic.2014.07.028
更新日期:2014-11-01 00:00:00
abstract:BACKGROUND:Little is known about the hand hygiene practices of surgical patients. Most of the research has been directed at the health care worker, and this may discount the role that hand hygiene of the surgical patient might play in surgical site infections. METHODS:A quasiexperimental, pretest/post-test study was c...
journal_title:American journal of infection control
pub_type: 临床试验,杂志文章
doi:10.1016/j.ajic.2012.05.029
更新日期:2013-06-01 00:00:00
abstract:BACKGROUND:Healthcare associated infections are associated with indwelling devices. Yet, data regarding prevalence of indwelling devices in noncritically ill hospitalized patients remains scant. METHODS:Adult, noncritically ill patients on general care, telemetry, and surgical floors at our quaternary care hospital we...
journal_title:American journal of infection control
pub_type: 杂志文章
doi:10.1016/j.ajic.2020.06.205
更新日期:2021-02-01 00:00:00
abstract:BACKGROUND:Blood culture contamination with gram-positive organisms is a common occurrence in patients suspected of bloodstream infections, especially in emergency departments. Although numerous research studies have investigated the cost implications of blood culture contamination, a contemporary systematic review of ...
journal_title:American journal of infection control
pub_type: 杂志文章
doi:10.1016/j.ajic.2018.12.020
更新日期:2019-08-01 00:00:00
abstract::The Association for Professionals in Infection Control and Epidemiology (APIC) began publishing their series of Elimination Guides in 2007. Since then, 9 Elimination Guides have been developed that cover a range of important infection prevention issues, including the prevention of catheter-related bloodstream infectio...
journal_title:American journal of infection control
pub_type: 杂志文章,实务指引
doi:10.1016/j.ajic.2010.08.003
更新日期:2010-10-01 00:00:00
abstract::Handwashing is the single most important procedure in the prevention of nosocomial infections and yet it remains the most violated of all infection control procedures. With a sequential intervention study in an intensive care unit we have demonstrated that poor handwashing practices are associated with a high nosocomi...
journal_title:American journal of infection control
pub_type: 杂志文章
doi:10.1016/0196-6553(89)90002-3
更新日期:1989-12-01 00:00:00