Abstract：
BACKGROUND:Thermally injured patients are at high risk for infections, including hospital acquired infections (HAIs). We modeled a twice-daily chlorhexidine gluconate (CHG) bath protocol aimed at decreasing HAIs. METHODS:Bathing with a 0.9% CHG solution in sterile water was provided twice daily as part of routine care. Institutional HAI prevention bundles were in place and did not change during the study. Baseline HAI rates were collected for 12 months before the quality study implementation. Centers for Disease Control and Prevention definitions for HAIs were used; our blinded Infection Control physician made each determination. This was an Institutional Review Board-exempt protocol. RESULTS:The study cohort included 203 patients before the quality trial and 277 patients after the quality trial. The median burn area was 25% of total body surface area. Baseline HAI rates were as follows: ventilator-associated pneumonia, 2.2 cases/1,000 ventilator-days; cathether-associated urinary tract infection, 2.7 cases/1,000 catheter-days; central line-associated bloodstream infection, 1.4 cases/1,000 device-days. With implementation of this protocol, the rates dropped to zero and have stayed at that level with the exception of 1 cathether-associated urinary tract infection. There were no untoward effects or observed delays in wound healing with this protocol. All of these changes were clinically significant, although not statistically significant; the study was not powered for statistical significance. CONCLUSIONS:Using this nurse-driven protocol, we decreased, in a sustainable manner, the HAI rate in our intensive care unit to zero. No integumentary difficulties or wound healing delays were related to this protocol.
journal_name
Am J Infect Controljournal_title
American journal of infection controlauthors
Popp JA,Layon AJ,Nappo R,Richards WT,Mozingo DWdoi
10.1016/j.ajic.2013.08.015subject
Has Abstractpub_date
2014-02-01 00:00:00pages
129-32issue
2eissn
0196-6553issn
1527-3296pii
S0196-6553(13)01218-2journal_volume
42pub_type
杂志文章abstract：:An increasing number of hospitals have implemented programs that permit their operating room (OR) personnel to launder their soiled "scrubs" at home. Not only have they not experienced an increase in the incidence of surgical site infections (SSIs), but they have also found the policy to be financially rewarding. Wher...
journal_title：American journal of infection control
pub_type： 杂志文章,评审
doi：10.1067/mic.2001.110366
更新日期：2001-02-01 00:00:00
abstract：BACKGROUND:Surgical site infections after joint arthroplasty are devastating complications and are influenced by patient, surgical, and operating room environmental factors. METHODS:In an effort to reduce the incidence of door openings (DOs) during total joint arthroplasty cases, this prospective observational study c...
journal_title：American journal of infection control
pub_type： 杂志文章
doi：10.1016/j.ajic.2017.12.019
更新日期：2018-06-01 00:00:00
abstract：:Surgical instrument trays are wrapped for sterilization, and these wraps are inspected by operating room personnel for defects before using the instruments. In this study, we intentionally damaged wraps, and these wraps were evaluated by operating room personnel. Examiners correctly identified a wrapper's sterile inte...
journal_title：American journal of infection control
pub_type： 杂志文章
doi：10.1016/j.ajic.2017.11.031
更新日期：2018-07-01 00:00:00
abstract：:Endoscope auditing is unique from other types of auditing normally completed as part of ongoing quality initiatives. When auditors walk into an endoscopy processing area, they are confronted with a variety of complex processes generally packed into a small space. Auditors are challenged to become experts on the proces...
journal_title：American journal of infection control
pub_type： 杂志文章
doi：10.1016/j.ajic.2019.06.029
更新日期：2020-01-01 00:00:00
abstract：BACKGROUND:Patient hand hygiene may be a useful strategy to prevent acquisition of pathogens and to reduce the risk for transmission by colonized patients. Several studies demonstrate that patients and long-term-care facility (LTCF) residents may have difficulty using hand hygiene products that are provided; however, n...
journal_title：American journal of infection control
pub_type： 杂志文章
doi：10.1016/j.ajic.2016.12.023
更新日期：2017-06-01 00:00:00
abstract：BACKGROUND:Routine hand hygiene effectively removes methicillin-resistant Staphylococcus aureus (MRSA) and/or vancomycin resistant Enterococcus (VRE) from the ungloved hands of healthcare workers (HCWs) who are caring for patients under contact precautions, when exposure to bodily fluids is not expected. METHODS:HCWs'...
journal_title：American journal of infection control
pub_type： 杂志文章
doi：10.1016/j.ajic.2018.01.013
更新日期：2018-07-01 00:00:00
abstract：:Intrahospital variations in antimicrobial profiles may be related to many factors. This study compared causative agents of nosocomial bloodstream infections between a neonatal intensive care unit (NICU) that adopted a ward-tailored antibiotic policy and adult intensive care units (ICUs). Data on organisms from blood c...
journal_title：American journal of infection control
pub_type： 杂志文章
doi：10.1016/j.ajic.2012.02.032
更新日期：2012-08-01 00:00:00
abstract：:We performed 4 years of active screening for multidrug resistant organism (MDRO) colonization among patients with a history of overseas hospitalization. Thirteen (56.5%) of 23 cases were positive for MDROs, which highlights the importance of preemptive infection control to prevent the spread of MDROs in this populatio...
journal_title：American journal of infection control
pub_type： 杂志文章
doi：10.1016/j.ajic.2016.06.040
更新日期：2016-11-01 00:00:00
abstract：:We evaluated the utility and usability of a spray and a wipe-based cleaner/disinfectant in a behavioral health setting where health care providers institute cleaning and disinfection procedures. The spray-based version resulted in significantly lower adenosine triphosphate readings after use compared with the wipe ver...
journal_title：American journal of infection control
pub_type： 杂志文章
doi：10.1016/j.ajic.2016.05.028
更新日期：2016-12-01 00:00:00
abstract：:An antimicrobial stewardship program was implemented throughout 2012 at a tertiary pediatric institution with guideline development preceding prospective audit and feedback starting in 2013. Meropenem use decreased over 62% during the next 5 years. Non-cystic fibrosis Pseudomonas aeruginosa isolate susceptibility to m...
journal_title：American journal of infection control
pub_type： 杂志文章
doi：10.1016/j.ajic.2019.05.001
更新日期：2019-12-01 00:00:00
abstract：BACKGROUND:There are multiple treatment options for the control of legionellae in premise hot water systems. Water chemistry plays a role in the efficacy of these treatments and should be considered when selecting a treatment. This study demonstrated the efficacy of copper-silver ionization (CSI) under alkaline water c...
journal_title：American journal of infection control
pub_type： 杂志文章
doi：10.1016/j.ajic.2015.05.018
更新日期：2015-09-01 00:00:00
abstract：OBJECTIVES:The World Health Organization recommends empowering patients/families to remind healthcare workers (HCWs) to perform hand hygiene (HH). We sought to understand acceptability of a family empowerment strategy in a Vietnamese pediatric intensive care unit (PICU). METHODS:With end-user input, we designed a tool...
journal_title：American journal of infection control
pub_type： 杂志文章
doi：10.1016/j.ajic.2020.05.030
更新日期：2020-12-01 00:00:00
abstract：INTRODUCTION:Preoperative nasal mupirocin has been shown to reduce surgical site infections (SSIs) in patients undergoing cardiac surgery. We analyzed the effect of mupirocin plus antiseptic body wash on SSI rate and etiology. METHODS:Prospective SSI surveillance was done for patients undergoing cardiac surgery before...
journal_title：American journal of infection control
pub_type： 杂志文章
doi：10.1016/j.ajic.2015.04.188
更新日期：2015-07-01 00:00:00
abstract：BACKGROUND:Community-associated Clostridioides difficile infections (CA-CDIs) share many risk factors with health care-associated cases, although the role of socioeconomic factors is poorly understood. This study estimates the influence of several census tract-level measures of socioeconomic status on CA-CDI incidence ...
journal_title：American journal of infection control
pub_type： 杂志文章
doi：10.1016/j.ajic.2018.12.014
更新日期：2019-07-01 00:00:00
abstract：BACKGROUND:Health care-associated opportunistic pathogens Staphylococcus aureus and Enterococcus faecium persist on dry environments and can contribute to organism transmission through contact. These organisms can be monitored on surfaces by culture, molecular methods, or metabolic assays. This study was designed to de...
journal_title：American journal of infection control
pub_type： 杂志文章
doi：10.1016/j.ajic.2017.07.027
更新日期：2018-01-01 00:00:00
abstract：BACKGROUND:No information is available on the financial impact of nosocomial pneumonia in Argentina. To calculate the cost of nosocomial pneumonia in intensive care units, a 5-year, matched cohort study was undertaken at 3 hospitals in Argentina. SETTING:Six adult intensive care units (ICU). METHODS:Three hundred sev...
journal_title：American journal of infection control
pub_type： 杂志文章
doi：10.1016/j.ajic.2004.08.008
更新日期：2005-04-01 00:00:00
abstract：BACKGROUND:Methicillin-resistant Staphylococcus aureus (MRSA) infections are a concern across the worldwide. METHODS:Antibiotic stewardship and hand hygiene programs were reinforced in a 2,000-bed tertiary hospital in South Korea where the methicillin resistance rate of Staphylococcus aureus is about 65%. The computer...
journal_title：American journal of infection control
pub_type： 杂志文章
doi：10.1016/j.ajic.2012.12.018
更新日期：2013-05-01 00:00:00
abstract：BACKGROUND:Filtering facepiece respirators are the most common respirator worn by US health care and industrial workers, yet little is known on the physiologic impact of wearing this protective equipment. METHODS:Twenty young, healthy subjects exercised on a treadmill at a low-moderate (5.6 km/h) work rate while weari...
journal_title：American journal of infection control
pub_type： 杂志文章
doi：10.1016/j.ajic.2012.02.037
更新日期：2013-01-01 00:00:00
abstract：BACKGROUND:Control chart methodology has been widely touted for monitoring and improving quality in the health care setting. P charts and U charts are frequently recommended for rate and ratio statistics, but their practical value in infection control may be limited because they (1) are not risk-adjusted, and (2) perfo...
journal_title：American journal of infection control
pub_type： 杂志文章
doi：10.1067/mic.2000.109883
更新日期：2000-12-01 00:00:00
abstract：BACKGROUND:The aim of this study was to evaluate the performance of a focused multivector ultraviolet (FMUV) system employing shadowless delivery with a 90-second disinfection cycle for patient care equipment inside and outside the operating room (OR) suite without manual-chemical disinfection. METHODS:A 5-point multi...
journal_title：American journal of infection control
pub_type： 杂志文章
doi：10.1016/j.ajic.2018.09.019
更新日期：2019-04-01 00:00:00
abstract：:The treatment of bacterial infections is increasingly complicated by the ability of bacteria to develop resistance to antimicrobial agents. Antimicrobial agents are often categorized according to their principal mechanism of action. Mechanisms include interference with cell wall synthesis (eg, beta-lactams and glycope...
journal_title：American journal of infection control
pub_type： 杂志文章,评审
doi：10.1016/j.ajic.2006.05.219
更新日期：2006-06-01 00:00:00
abstract：BACKGROUND:Stethoscopes may serve as vehicles for transmission of bacteria among patients. The aim of this study was to assess the efficacy of antimicrobial copper surfaces to reduce the bacterial concentration associated with stethoscope surfaces. METHODS:A structured prospective trial involving 21 health care provid...
journal_title：American journal of infection control
pub_type： 临床试验,杂志文章
doi：10.1016/j.ajic.2017.01.030
更新日期：2017-06-01 00:00:00
abstract：BACKGROUND:The purpose of this educational project was to assess the effect of several interventions on the frequency of handwashing among elementary public school children. METHODS:Participants in this project were first-graders and fourth-graders from jurisdictions within a mid-Atlantic metropolitan area. Phase I in...
journal_title：American journal of infection control
pub_type： 临床试验,杂志文章
doi：10.1016/s0196-6553(98)80011-4
更新日期：1998-06-01 00:00:00
abstract：BACKGROUND:It has been shown that nontoxic concentrations of ethanol are absorbed after hand hygiene using ethanol-based hand rubs. This study investigated whether absorption of propan-1-ol and propan-2-ol from commercially available hand rubs results in measurable concentrations after use. METHODS:The pulmonary and d...
journal_title：American journal of infection control
pub_type： 杂志文章
doi：10.1016/j.ajic.2011.03.009
更新日期：2012-04-01 00:00:00
abstract：BACKGROUND:Although isolation precautions are an important aspect of hospital infection control, current rates of isolation in a pediatric hospital and rates of compliance with established precautions are unknown. We therefore initiated hospital-wide point prevalence studies to determine unit-specific rates of patient ...
journal_title：American journal of infection control
pub_type： 杂志文章
doi：10.1016/j.ajic.2006.03.012
更新日期：2007-05-01 00:00:00
abstract：:The overall risk of infection from medical devices is very low, but high infection transmission rates have been related to inadequate reprocessing of arthroscopic shavers and flexible duodenoscopes. Monitoring of manual and automated cleaning is needed to ensure that inadequately cleaned medical devices are recleaned ...
journal_title：American journal of infection control
pub_type： 杂志文章,评审
doi：10.1016/j.ajic.2012.12.006
更新日期：2013-05-01 00:00:00
abstract：BACKGROUND:Children in child care settings have a high infectious burden. They are frequently exposed to sanitizing and disinfecting agents, whose toxicities have not been studied in these settings. Current guidance on the preferred disinfection agents for child care is vague. METHODS:This article combines 2 different...
journal_title：American journal of infection control
pub_type： 杂志文章
doi：10.1016/j.ajic.2018.06.013
更新日期：2019-01-01 00:00:00
abstract：BACKGROUND:Studies taken from different hospitalized patient populations, environments, and geographic regions reveal differences in the numbers and species of organisms colonizing the skin. Our aim was to determine the types and amounts of skin flora, and examine the factors associated with variations in microbial ski...
journal_title：American journal of infection control
pub_type： 杂志文章
doi：10.1067/mic.2003.64
更新日期：2003-04-01 00:00:00
abstract：BACKGROUND:Reusable bedpans and urinals are frequently cleaned and decontaminated using washer-disinfectors (WDs) that may be located in the central processing department (CPD) or on the ward. The objective of this study was to determine how efficiently the WDs provided cleaning and to evaluate the ability of such WDs ...
journal_title：American journal of infection control
pub_type： 杂志文章
doi：10.1016/j.ajic.2007.04.277
更新日期：2008-02-01 00:00:00
abstract：BACKGROUND:Burkholderia cepacia complex (Bcc) is well-known for intrinsic resistance to certain antiseptics. We experienced a sudden rise in Bcc bloodstream infections in a 786-bed hospital. An investigation was conducted to identify the source and to intervene in the ongoing infections. METHODS:The cases were defined...
journal_title：American journal of infection control
pub_type： 杂志文章
doi：10.1016/j.ajic.2014.11.010
更新日期：2015-03-01 00:00:00
