Short-term oral folic acid supplementation enhances endothelial function in patients with type 2 diabetes.

abstract：BACKGROUND:Although insulin resistance (IR) is thought to be related to vascular dysfunction, the difference in the relationship of IR to microvasculature and macrovasculature reactivity has not yet been clarified. The present study was conducted to clarify whether the IR is more closely related to the macrovasculature...

journal_title：American journal of hypertension

authors： Yoshida M,Tomiyama H,Yamada J,Matsumoto C,Odaira M,Shiina K,Yamashina A

更新日期：2010-05-01 00:00:00

abstract：:This article examines the results of the Joint National Committee's Fifth Report on the treatment of hypertension (JNC-V), especially regarding the economic arguments put forth therein. Economics are a poor basis for treatment decisions, as the cheapest therapies may not be the best for any given patient. Broad treatm...

journal_title：American journal of hypertension

authors： Ménard J

更新日期：1994-10-01 00:00:00

abstract：:Blood pressure normally follows a characteristic pattern throughout the 24 h cycle with daytime pressures higher than nighttime pressures. Patients lacking a nocturnal decrease in pressure have a higher incidence of end organ damage. This investigation was designed to characterize the diurnal pattern of blood pressure...

journal_title：American journal of hypertension

authors： Marx MA,Gardner SF,Ketel BL

更新日期：1996-08-01 00:00:00

abstract：:The purpose of this study has been to test the hypothesis of an alpha 2-adrenoreceptor alteration in human essential hypertension. The design of the study involved the oral administration of 10 mg yohimbine, an alpha 2-adrenergic antagonist, to 25 healthy volunteers and 29 sex- and age-matched untreated hypertensive p...

journal_title：American journal of hypertension

authors： Musso NR,Vergassola C,Pende A,Lotti G

更新日期：1995-06-01 00:00:00

abstract：:It has been speculated for some time that various antihypertensive medications may have a deleterious effect on respiration during sleep and thereby enhance the apparent association between hypertension and sleep apnea/hypopnea (SAH). However, there are few data to support this contention. The present study used a dou...

journal_title：American journal of hypertension

authors： Bartel PR,Loock M,Becker P,Robinson E,van der Meyden C,Rossouw S

更新日期：1997-06-01 00:00:00

abstract：:This study examined the effects of alterations in salt-intake on blood pressure (BP) in rats chronically treated intravenously with or without the nitric oxide synthase (NOS) inhibitor N(G)-nitro-L-arginine methyl ester (L-NAME) (8.6 mg/kg/day). The changes in mean arterial pressure (MAP), the renal cortical and medul...

journal_title：American journal of hypertension

authors： Nakanishi K,Hara N,Nagai Y

更新日期：2002-02-01 00:00:00

abstract：:Increased insulinemic response to an oral glucose load has been demonstrated in Dahl salt-sensitive hypertensive rats. To determine whether this abnormality is mediated at the level of the insulin receptor, we compared insulin receptor binding and mRNA levels in tissues of Dahl salt-sensitive rats (DS) and in their no...

journal_title：American journal of hypertension

authors： Sechi LA,Griffin CA,Zingaro L,Catena C,De Carli S,Schambelan M,Bartoli E

更新日期：1997-11-01 00:00:00

abstract：BACKGROUD:Declining renal function is an independent risk factor for all-cause mortality in cardiovascular disease. Visfatin has been described as a marker of inflammation and endothelial dysfunction, but whether circulating visfatin levels are predictive to a subsequent decline in renal function remains unclear. METH...

journal_title：American journal of hypertension

authors： Hsu CY,Huang PH,Chen TH,Chiang CH,Leu HB,Huang CC,Chen JW,Lin SJ

更新日期：2016-04-01 00:00:00

abstract：BACKGROUND:Our aim was to assess whether home blood pressure (HBP) and ambulatory BP monitoring measurement (ABPM), in addition to office BP (OBP) predict changes of cardiovascular biomarkers during antihypertensive treatment. METHODS:Two hundred and fifty-two hypertensive patients (mean age, 68 years; men: 41%) under...

journal_title：American journal of hypertension

authors： Yano Y,Hoshide S,Shimizu M,Eguchi K,Ishikawa J,Ishikawa S,Shimada K,Kario K

更新日期：2012-03-01 00:00:00

abstract：:The effects of angiotensin converting enzyme (ACE) inhibitors on the release of angiotensin II (Ang II) from isolated mesenteric arteries of spontaneously hypertensive rats (SHRs) were examined. Delapril, enalapril, and captopril suppressed Ang II release in a dose-dependent manner. After oral treatment with delapril ...

journal_title：American journal of hypertension

authors： Higashimori K,Nakamaru M,Tabuchi Y,Nagano M,Mikami H,Ogihara T,Inagami T

更新日期：1991-01-01 00:00:00

abstract：:In the present study, age- and calcium-related changes in the membrane fluidity of erythrocytes were examined in patients with essential hypertension by use of electron spin resonance method (ESR). The erythrocytes were obtained from patients with essential hypertension. We examined the ESR spectra for a fatty acid sp...

journal_title：American journal of hypertension

authors： Tsuda K,Masuyama Y

更新日期：1990-09-01 00:00:00

abstract：:Longitudinal studies in children have tracked blood pressure through childhood and from childhood into adult life. However, many children do not maintain their rank during these periods of observation. Several of the factors contributing to maintenance of rank order are reviewed, such as initial level of blood pressur...

journal_title：American journal of hypertension

authors： Mahoney LT,Clarke WR,Burns TL,Lauer RM

更新日期：1991-11-01 00:00:00

abstract：:Increased adrenergic activity has been suggested to mediate the hypertension associated with hyperinsulinemia. This study tested whether combined alpha1- and beta-adrenergic receptor blockade would prevent insulin-induced hypertension when euglycemia was maintained by continuous intravenous glucose infusion. Sprague-D...

journal_title：American journal of hypertension

authors： Keen HL,Brands MW,Alonso-Galicia M,Hall JE

更新日期：1996-12-01 00:00:00

abstract：OBJECTIVE:To determine the effects of orthostatic hypotension (OH) measurement timing on its associations with dizziness, falls, fractures, cardiovascular disease (CVD), and mortality. METHODS:We analyzed OH measurements from the Action to Control Cardiovascular Risk in Diabetes BP trial, which evaluated two blood pre...

journal_title：American journal of hypertension

authors： Juraschek SP,Lipsitz LA,Beach JL,Mukamal KJ

更新日期：2019-06-11 00:00:00

abstract：BACKGROUND:There may be a link among stress, adrenal medullary activation, and the development of hypertension. Obesity is characterized by sympathetic activation and predisposes to hypertension, but may be associated with low or normal adrenal medullary activity. We hypothesized that plasma epinephrine (E) levels and ...

journal_title：American journal of hypertension

authors： Reims HM,Fossum E,Høieggen A,Moan A,Eide I,Kjeldsen SE

更新日期：2004-07-01 00:00:00

abstract：:Angiotensin II (Ang II) and transforming growth factor-beta (TGF-beta) modulate cell growth and metabolism. Our objective was to evaluate the effect of Ang II on the characteristics and expression of TGF-beta receptors on vascular smooth muscle cells (VSMC) from Wistar-Kyoto rats. The addition of TGF-beta1 elicited a ...

journal_title：American journal of hypertension

authors： Fukuda N,Hu WY,Kubo A,Kishioka H,Satoh C,Soma M,Izumi Y,Kanmatsuse K

更新日期：2000-02-01 00:00:00

abstract：BACKGROUND:Left ventricular (LV) concentric geometry and hypertrophy, depressed wall mechanics, and abnormal diastolic properties have been described in the diabetic heart. However, the cardiac response to dynamic exercise in diabetic patients remains controversial. The present study assessed strain rate (SR) imaging d...

journal_title：American journal of hypertension

authors： Galderisi M,de Simone G,Innelli P,Turco A,Turco S,Capaldo B,Riccardi G,de Divitiis O

更新日期：2007-05-01 00:00:00

abstract：BACKGROUND:Microalbuminuria is recognized as a marker of generalized vascular dysfunction. However, the associations between microalbuminuria and pulse wave velocity (PWV), carotid intima-media thickness (IMT), and ambulatory blood pressure (ABP), respectively, have not been investigated. METHODS:Brachial-ankle PWV (b...

journal_title：American journal of hypertension

authors： Ishikawa T,Hashimoto J,Morito RH,Hanazawa T,Aikawa T,Hara A,Shintani Y,Metoki H,Inoue R,Asayama K,Kikuya M,Ohkubo T,Totsune K,Hoshi H,Satoh H,Imai Y

更新日期：2008-04-01 00:00:00

abstract：BACKGROUND:One effort to improve hypertension care in the United States is the development of the "Hypertension Specialist" program with appropriate training and certification of individual physicians. METHODS:We examined the impact of a hypertension clinic on blood pressure (BP) levels and control. RESULTS:By one ye...

journal_title：American journal of hypertension

authors： Bansal N,Tendler BE,White WB,Mansoor GA

更新日期：2003-10-01 00:00:00

abstract：:It is known that calcium induces the formation of potent vasodilators in endothelial cells and vasoconstriction in smooth muscle cells, whereas in the renal parenchyma, it modulates sodium excretion through vascular and tubular mechanisms. Consequently, an increased concentration of calcium in renal circulation may in...

journal_title：American journal of hypertension

authors： Lahera V,Ruilope LM,Romero JC

更新日期：1991-07-01 00:00:00

abstract：BACKGROUND:Essential hypertension ranks among the strongest cardiovascular risk factors. Cytokine production by monocytes plays a key role in atherosclerosis development and acute coronary syndromes. We investigated whether stimulated monocyte cytokine release and its inhibition by glucocorticoids would differ between ...

journal_title：American journal of hypertension

authors： Wirtz PH,von Känel R,Frey K,Ehlert U,Fischer JE

更新日期：2004-06-01 00:00:00

abstract：BACKGROUND:The "nondipping" pattern (NDP) of blood pressure, characterized by the absence of the reduction in blood pressure (BP) that typically takes place during the night time, has been associated with elevated cardiovascular morbidity, including stroke, myocardial infarction, and sudden cardiac-related death. In va...

journal_title：American journal of hypertension

authors： Myredal A,Friberg P,Johansson M

更新日期：2010-03-01 00:00:00

abstract：BACKGROUND:Pulse pressure, a measure of central arterial stiffness and a predictor of cardiovascular mortality, has known genetic components. METHODS:To localize the genetic effects of pulse pressure, we conducted a genome-wide linkage analysis of 1,892 American-Indian participants of the Strong Heart Family Study (SH...

journal_title：American journal of hypertension

authors： Franceschini N,MacCluer JW,Rose KM,Rutherford S,Cole SA,Laston S,Göring HH,Diego VP,Roman MJ,Lee ET,Best LG,Howard BV,Fabsitz RR,North KE

更新日期：2008-02-01 00:00:00

abstract：BACKGROUND:Hypertension is a risk factor for coronary heart disease (CHD), but the causes of hypertension remain largely unknown. Genetic variation is thought to contribute to the etiology of hypertension. We tested a single-nucleotide polymorphism (SNP) (Lys67Arg, rs197922) in the Golgi SNAP Receptor Complex Member 2 ...

journal_title：American journal of hypertension

authors： Meyer TE,Shiffman D,Morrison AC,Rowland CM,Louie JZ,Bare LA,Ross DA,Arellano AR,Chasman DI,Ridker PM,Pankow JS,Coresh J,Malloy MJ,Kane JP,Ellis SG,Devlin JJ,Boerwinkle E

更新日期：2009-02-01 00:00:00

abstract：:The aim of this study was to assess whether an interaction exists between the renin-angiotensin system and the sympathetic nervous system at the level of the adrenal medulla during insulin-induced hypoglycemia in normal humans. Seventeen healthy volunteers were studied in a randomized, single-dose, double-blind, cross...

journal_title：American journal of hypertension

authors： Madsen BK,Hølmer P,Ibsen H,Christensen NJ

更新日期：1992-06-01 00:00:00

abstract：BACKGROUND:Experimentally induced sleep deprivation can raise blood pressure (BP) and worsen hypertension. We recently reported a significantly higher prevalence of obstructive sleep apnea (OSA) and reduced rapid eye movement (REM) sleep time in drug-resistant hypertensives compared to controlled hypertensives. The obj...

journal_title：American journal of hypertension

authors： Friedman O,Bradley TD,Ruttanaumpawan P,Logan AG

更新日期：2010-02-01 00:00:00

abstract：:The syndrome of apparent mineralocorticoid excess (AME) is characterized by persistent hypertension and hypokalemia, which is caused by impaired inactivation of cortisol (F) to cortisone (E). The thyroid hormone has been known to influence the F to E conversion leading to efficacious inactivation of F into E. However,...

journal_title：American journal of hypertension

authors： Inagaki K,Otsuka F,Otani H,Sato C,Miyoshi T,Ogura T,Makino H

更新日期：2007-01-01 00:00:00

abstract：:The ability of a beta-blocker to inhibit vascular sympathetic nerve activity associated with hypertension was studied in DOCA-salt hypertension in rats. A seven week treatment of DOCA and salt resulted in a significant increase in the systolic blood pressure of the uninephrectomized rats. The administration of propran...

journal_title：American journal of hypertension

authors： Tsuda K,Masuyama Y

更新日期：1991-01-01 00:00:00

abstract：BACKGROUND:Activation of phosphatidylinositol 3-kinase (PI3K)-Akt signaling by statins increases the activity of endothelial nitric oxide synthase (eNOS). We investigate whether statins (pitavastatin) improve cardiac function and remodeling via eNOS production associated with the PI3K-Akt signaling pathway, Rho-kinase ...

journal_title：American journal of hypertension

authors： Kobayashi N,Takeshima H,Fukushima H,Koguchi W,Mamada Y,Hirata H,Machida Y,Shinoda M,Suzuki N,Yokotsuka F,Tabei K,Matsuoka H

更新日期：2009-02-01 00:00:00

abstract：BACKGROUND:Type B acute aortic dissection (AAD) carries a high short- and midterm mortality rate; however, knowledge related to long-term outcome is largely incomplete. The objective of this study was to identify long-term predictors including antihypertensive medications in type B AAD. METHODS:We conducted a clinical...

journal_title：American journal of hypertension

authors： Sakakura K,Kubo N,Ako J,Fujiwara N,Funayama H,Ikeda N,Nakamura T,Sugawara Y,Yasu T,Kawakami M,Momomura S

更新日期：2009-04-01 00:00:00