Fenofibrate effectively reduces remnants, and small dense LDL, and increases HDL particle number in hypertriglyceridemic men - a nuclear magnetic resonance study.

abstract：:Normal and alloxan diabetic rats were kept on a 0.25% cholesterol diet for 12 months and the changes in serum cholesterol levels, and fecal excretion of sterols and bile acids were examined to elucidate the influence of changes in bile acid metabolism on manifestations of hypercholesterolemia and development of athero...

journal_title：Journal of atherosclerosis and thrombosis

authors： Uchida K,Satoh T,Takase H,Nomura Y,Takasu N,Kurihara H,Takeuchi N

更新日期：1996-01-01 00:00:00

abstract：AIM:The prospective, randomized, multicenter Myocardial Ischemia Treated with Percutaneous Coronary Intervention and Plaque Regression by Lipid Lowering & Blood Pressure Controlling assessed by Intravascular Ultrasonography (MILLION) study demonstrated that combined treatment with atorvastatin and amlodipine enhanced c...

journal_title：Journal of atherosclerosis and thrombosis

authors： Sakata K,Gamou T,Tada H,Hayashi K,Ino H,Yamagishi M,Masa-aki Kawashiri.,behalf of the MILLION Study Group.

更新日期：2019-05-01 00:00:00

abstract：:The constellation of metabolic abnormalities including centrally distributed obesity, decreased high-density lipoprotein cholesterol (HDL-C), elevated triglycerides, elevated blood pressure (BP), and hyperglycaemia is known as the metabolic syndrome. Associated with a 3 fold and 2 fold increase in type 2 diabetes and ...

journal_title：Journal of atherosclerosis and thrombosis

authors： Zimmet P,Magliano D,Matsuzawa Y,Alberti G,Shaw J

更新日期：2005-01-01 00:00:00

abstract：AIM:Atrial fibrillation (AF) is characterized by the development of thromboembolic events and is more prevalent among end-stage renal disease patients than in the general population. Vascular access thrombosis (VAT) is a major morbidity in chronic hemodialysis (HD) patients; however, the association between AF and VAT ...

journal_title：Journal of atherosclerosis and thrombosis

authors： Chou CY,Chen JY,Liu JH,Liu YL,Lin HH,Yang YF,Wang SM,Kuo HL,Huang CC

更新日期：2011-01-01 00:00:00

abstract：:Inflammation and oxidative stress play key roles in atherosclerotic plaque instability, and plaque rupture/erosion and subsequent thrombus formation constitute the principal mechanisms of total vessel occlusion and acute ST-elevation myocardial infarction (STEMI). Plaque disruption triggers the formation of initial pl...

journal_title：Journal of atherosclerosis and thrombosis

authors： Yunoki K,Naruko T,Sugioka K,Inaba M,Itoh A,Haze K,Yoshiyama M,Ueda M

更新日期：2013-01-01 00:00:00

abstract：:A 77-year-old woman with type II diabetes mellitus was admitted to our hospital in August/ 1995 with severe hyperlipidemia. She had taken feedings through a nasogastric tube with 1000 ml (1000 kcal) of Ensureliquid daily since 1993 because of the muscle weakness after rhabdomyolysis. Her serum total cholesterol was 51...

journal_title：Journal of atherosclerosis and thrombosis

authors： Tanaka S,Miki T,Hsieh ST,Kim JI,Yasumoto T,Taniguchi T,Ishikawa Y,Yokoyama M

更新日期：2003-01-01 00:00:00

abstract：AIM:Atherosclerosis (AS) characterized as a chronic inflammatory disease. Multiple immune cells and inflammatory cytokines, such as high mobility group protein (HMGB1), regulatory T (Treg) cells, T helper (Th17) cells, and inflammation-related cytokines, play a key role in its pathophysiology. A large number of studies...

journal_title：Journal of atherosclerosis and thrombosis

authors： Ding JW,Zheng XX,Zhou T,Tong XH,Luo CY,Wang XA

更新日期：2016-06-01 00:00:00

abstract：AIM:Although distal embolization during percutaneous coronary intervention (PCI) for acute myocardial infarction (AMI) deteriorates cardiac function, whether distal protection (DP) can improve prognosis is still controversial. We investigated whether a filter-type DP device, Filtrap®, could improve long-term outcomes a...

journal_title：Journal of atherosclerosis and thrombosis

authors： Teramoto R,Sakata K,Miwa K,Matsubara T,Yasuda T,Inoue M,Okada H,Kanaya H,Kawashiri MA,Yamagishi M,Hayashi K

更新日期：2016-12-01 00:00:00

abstract：:Several reports have suggested that HDL has anti-oxidative actions. We investigated the relationship between HDL-cholesterol (HDL-C) and malondialdehyde-modified LDL (MDA-LDL) concentrations using enzyme linked immunosolvent assay. We divided our study subjects into four groups on the basis of concentrations of trigly...

journal_title：Journal of atherosclerosis and thrombosis

authors： Kondo A,Li J,Manabe M,Saito K,Kanno T,Maekawa M

更新日期：2003-01-01 00:00:00

abstract：AIM:The arterial pressure-volume index (API) and arterial velocity-pulse index (AVI) are novel measurement indices of arterial stiffness. This study was performed to examine the screening validity of the API and AVI for preclinical atherosclerosis in Japanese community-dwelling adults. METHODS:We conducted a cross-sec...

journal_title：Journal of atherosclerosis and thrombosis

authors： Yamanashi H,Koyamatsu J,Nagayoshi M,Shimizu Y,Kawashiri SY,Kondo H,Fukui S,Tamai M,Maeda T

更新日期：2018-09-01 00:00:00

abstract：:Cell degeneration and collagenosis are the main features in atherosclerotic plaque. We examined the effects of human low density lipoprotein (LDL) on cultured rabbit aortic smooth muscle cells (SMCs). Copper oxidized LDL (LDL+Cu) injured the SMCs more than did native LDL. Cytotoxicity of oxidized LDL was prevented by ...

journal_title：Journal of atherosclerosis and thrombosis

authors： Jimi S,Sakata N,Takebayashi S

更新日期：1994-01-01 00:00:00

abstract：AIM:Ultrasound protocols to measure carotid intima media thickness (CIMT) differ considerably with regard to the inclusion of the number of carotid segments and angles used. Detailed information on the completeness of CIMT information is often lacking in published reports, and at most, overall percentages are presented...

journal_title：Journal of atherosclerosis and thrombosis

authors： Dogan S,Duivenvoorden R,Grobbee DE,Kastelein JJ,Shear CL,Evans GW,Visseren FL,Bots ML,Radiance 1 and 2 Study Groups.

更新日期：2010-05-01 00:00:00

abstract：AIM:Homocysteine is associated with increased arterial resistance and eventually causes luminal reduction. The purpose of the present study was to evaluate an association between the plasma concentration of total homocysteine (tHcy) and stenosis or occlusion of the internal carotid artery (ICA) in patients with ischemi...

journal_title：Journal of atherosclerosis and thrombosis

authors： Jeong SK,Seo JY,Cho YI

更新日期：2010-09-30 00:00:00

abstract：AIM:Moderate alcohol consumption appears to confer some protection against coronary heart disease, which is related to an increase in high-density lipoprotein cholesterol (HDL-C). The genotype of aldehyde dehydrogenase 2 (ALDH2) is closely related to alcohol metabolism but a relationship between ALDH2 genotypes and HDL...

journal_title：Journal of atherosclerosis and thrombosis

authors： Wada M,Daimon M,Emi M,Iijima H,Sato H,Koyano S,Tajima K,Kawanami T,Kurita K,Hunt SC,Hopkins PN,Kubota I,Kawata S,Kato T

更新日期：2008-08-01 00:00:00

abstract：AIM:To determine the effects of exercise training on total and high molecular weight (HMW) adiponectin and adiponectin oligomeric distribution. METHODS:A randomized parallel-design study (n=53; 40 women and 13 men; age range, 32?65 years) was conducted at a fitness club between April 2006 and July 2007. Participants w...

journal_title：Journal of atherosclerosis and thrombosis

authors： Ando D,Hosaka Y,Suzuki K,Yamagata Z

更新日期：2009-01-01 00:00:00

abstract：AIM:Hypercholesterolemic patients with inflammation are at high risk for cardiovascular events. Statins exert anti-inflammatory action independent of their cholesterol-lowering action. This study sought to clarify whether statin therapy reduces inflammatory markers in hypercholesterolemic patients and to determine fact...

journal_title：Journal of atherosclerosis and thrombosis

authors： Horiuchi Y,Hirayama S,Soda S,Seino U,Kon M,Ueno T,Idei M,Hanyu O,Tsuda T,Ohmura H,Miida T

更新日期：2010-07-30 00:00:00

abstract：AIMS:Profiling of lipoproteins can predict risk of cardiovascular disease; gel permeation high-performance liquid chromatography (HPLC) improves prediction accuracy by providing detailed data for specific lipoprotein subclasses. This study applied HPLC to examine the effects of evolocumab, which effectively treats hype...

journal_title：Journal of atherosclerosis and thrombosis

authors： Masuda D,Kiyosue A,Hirayama A,Shimauchi J,López JAG,Miyawaki K,Yamashita S

更新日期：2020-11-01 00:00:00

abstract：AIM:Evidence is lacking about whether urinary stones are associated with the subsequent risk of cardiovascular diseases. Herein, we investigated the association between history of urinary stones and the risk of coronary heart disease (CHD) and stroke among middle-aged Japanese. METHODS:This cohort study included 89,03...

journal_title：Journal of atherosclerosis and thrombosis

authors： Arafa A,Eshak ES,Iso H,Shirai K,Muraki I,Sawada N,Tsugane S,JPHC Study Group.

更新日期：2020-11-01 00:00:00

abstract：:Zetia (ezetimibe) is a selective cholesterol absorption inhibitor, which potently inhibits the absorption of biliary and dietary cholesterol from the small intestine without affecting the absorption of fat-soluble vitamins, triglycerides or bile acids. Ezetimibe reduces the small intestinal enterocyte uptake and absor...

journal_title：Journal of atherosclerosis and thrombosis

authors： Davis HR,Veltri EP

更新日期：2007-06-01 00:00:00

abstract：AIM:The INK4b-ARF-INK4a locus in the chromosome 9p21 region is known to play an important role in the development of atherosclerosis. The INK4/ARF transcript p16(INK4a) inhibits the activity of the cyclin-dependent kinases CDK4/CDK6 and arrests cell-cycle progression. CDK inhibitors also regulate G1/S phase progression...

journal_title：Journal of atherosclerosis and thrombosis

authors： Bayoglu B,Arslan C,Gode S,Kaya Dagistanli F,Arapi B,Burc Deser S,Dirican A,Cengiz M

更新日期：2014-01-01 00:00:00

abstract：AIM:The aim of this study was to assess the association between weight change and mortality due to cardiovascular diseases (CVDs) in a Japanese population. METHODS:We used the data of a population-based prospective cohort study that was conducted from 1988 to 1990 in 45 areas throughout Japan. Among a total of 69,681 ...

journal_title：Journal of atherosclerosis and thrombosis

authors： Okada C,Kubota Y,Eshak ES,Cui R,Tamakoshi A,Iso H,and the JACC Study Group.

更新日期：2021-01-01 00:00:00

abstract：AIMS:Cardiovascular disease (CVD) remains the leading cause of death worldwide despite improvements in the treatment of atherosclerosis, an inflammatory disease and major underlying cause of CVD. Monocytes, an innate immune cell type, are linked to CVD progression; however, given their heterogeneity, the association be...

journal_title：Journal of atherosclerosis and thrombosis

authors： SahBandar IN,Ndhlovu LC,Saiki K,Kohorn LB,Peterson MM,D'Antoni ML,Shiramizu B,Shikuma CM,Chow DC

更新日期：2020-05-01 00:00:00

abstract：AIM:Factor VII activating protease (FSAP) is a plasma serine protease involved in hemostasis and remodeling processes. Increased levels of circulating FSAP during pregnancy and in women using oral contraceptives (OCs) indicate that the hormonal status critically influences FSAP expression. In this respect, the aim of t...

journal_title：Journal of atherosclerosis and thrombosis

authors： Parahuleva MS,Langanke E,Hölschermann H,Parviz B,Abdallah Y,Stracke S,Tillmanns H,Kanse SM

更新日期：2012-01-01 00:00:00

abstract：AIM:In animals, dietary energy restriction is reported to increase longevity, whereas in humans, all cohort studies from Western countries have not shown an association between the low energy intake and longevity. We examined the association between total energy intake and longevity in Japan where dietary pattern is di...

journal_title：Journal of atherosclerosis and thrombosis

authors： Nagai M,Ohkubo T,Miura K,Fujiyoshi A,Okuda N,Hayakawa T,Yoshita K,Arai Y,Nakagawa H,Nakamura K,Miyagawa N,Takashima N,Kadota A,Murakami Y,Nakamura Y,Abbott RD,Okamura T,Okayama A,Ueshima H,NIPPON DATA80 Research Gro

更新日期：2016-01-01 00:00:00

abstract：:Although the human liver comprises approximately 2.8% of the body weight, it plays a central role in the control of energy metabolism. While the biochemistry of energy substrates such as glucose, fatty acids, and ketone bodies in the liver is well understood, many aspects of the overall control system for hepatic meta...

journal_title：Journal of atherosclerosis and thrombosis

authors： Yahagi N

更新日期：2017-01-01 00:00:00

abstract：AIM:Both vascular function and structure are independent predictors of cardiovascular events. The purpose of this study was to evaluate vascular function and structure of a leg artery in patients with peripheral artery disease (PAD). METHODS:We measured flow-mediated vasodilatation (FMD) and nitroglycerine-induced vas...

journal_title：Journal of atherosclerosis and thrombosis

authors： Iwamoto A,Kajikawa M,Maruhashi T,Iwamoto Y,Oda N,Kishimoto S,Matsui S,Kihara Y,Chayama K,Goto C,Noma K,Aibara Y,Nakashima A,Higashi Y

更新日期：2016-11-01 00:00:00

abstract：AIM:The purpose of this study is to investigate the impact of arterial stiffness assessed using Cardio-ankle Vascular Index (CAVI) on long-term outcome after acute coronary syndrome (ACS). METHODS:A total of 387 consecutive patients (324 males; age, 64±11 years) with ACS were enrolled. We examined CAVI and brachial-an...

journal_title：Journal of atherosclerosis and thrombosis

authors： Kirigaya J,Iwahashi N,Tahakashi H,Minamimoto Y,Gohbara M,Abe T,Akiyama E,Okada K,Matsuzawa Y,Maejima N,Hibi K,Kosuge M,Ebina T,Tamura K,Kimura K

更新日期：2020-07-01 00:00:00

abstract：AIM:Epicardial adipose tissue (EAT) may be associated with arrhythmogenesis. P-wave indices such as P-wave dispersion and P-wave variation indicated a slowed conduction velocity within the atria. This study investigated the effect of dapagliflozin on EAT volume and P-wave indices. METHODS:In the present ad hoc analysi...

journal_title：Journal of atherosclerosis and thrombosis

authors： Sato T,Aizawa Y,Yuasa S,Fujita S,Ikeda Y,Okabe M

更新日期：2020-12-01 00:00:00

abstract：AIM:Was to evaluate the role of seven matrix metalloproteinase (MMP) polymorphisms in the genetic susceptibility to develop myocardial infarction in Mexican individuals. METHODS:Seven polymorphisms in the MMP genes were genotyped by 5' exonuclease TaqMan genotyping assays in 300 patients with myocardial infarction and...

journal_title：Journal of atherosclerosis and thrombosis

authors： Pérez-Hernández N,Vargas-Alarcón G,Martínez-Rodríguez N,Martínez-Ríos MA,Peña-Duque MA,Peña-Díaz Ade L,Valente-Acosta B,Posadas-Romero C,Medina A,Rodríguez-Pérez JM

更新日期：2012-01-01 00:00:00

abstract：:Recent findings suggest that the oxidative modification of low-density lipoproteins (LDL) and an increase in triglyceride-rich lipoprotein particles including chylomicron remnants contribute to the progression of atherosclerosis, as does the inflammatory response. We therefore examined whether and how these lipoprotei...

journal_title：Journal of atherosclerosis and thrombosis

authors： Okumura T,Fujioka Y,Morimoto S,Masai M,Sakoda T,Tsujino T,Kashiwamura S,Okamura H,Ohyanagi M

更新日期：2006-02-01 00:00:00