Thrombus aspiration therapy and coronary thrombus components in patients with acute ST-elevation myocardial infarction.

abstract：AIM:Macrophage migration inhibitory factor (MIF) is known as a pro-inflammatory cytokine that regulates a broad spectrum of inflammatory reactions. MIF is expressed in vascular smooth muscle cells (VSMCs), and inhibition of the progression of atherosclerosis was observed in MIF-deficient atherosclerotic mice. However, ...

journal_title：Journal of atherosclerosis and thrombosis

authors： Okamoto T,Atsumi T,Shimizu C,Yoshioka N,Koike T

更新日期：2008-02-01 00:00:00

abstract：:We investigated in vitro effect of simvastatin, a potent 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor, on the proliferation of human and bovine endothelial cells (EC) compared to that of bovine smooth muscle cells (SMC). Cells were cultured in a medium supplemented with 10% normal serum (FBS). S...

journal_title：Journal of atherosclerosis and thrombosis

authors： Sato I,Ma L,Ikeda M,Morita I,Murota S

更新日期：1998-01-01 00:00:00

abstract：AIM:To compare the responsiveness to clopidogrel in patients who were prescribed two different types of statins, atorvastatin vs. rosuvastatin, following percutaneous coronary intervention. METHODS:A total of 915 patients were randomized according to the antiplatelet therapy strategy in the CILON-T trial. In this subg...

journal_title：Journal of atherosclerosis and thrombosis

authors： Suh JW,Cha MJ,Lee SP,Chae IH,Bae JH,Kwon TG,Bae JW,Cho MC,Rha SW,Kim HS

更新日期：2014-01-01 00:00:00

abstract：AIM:We examined the effects of mild hyperbaric oxygen on the properties of the soleus muscle in rats with metabolic syndrome. METHODS:Five-week-old metabolic syndrome (SHR/NDmcr-cp, cp/cp) rats were divided into normobaric (CP) and mild hyperbaric oxygen (CP-H) groups (n=5/group). In addition, 5-week-old Wistar rats w...

journal_title：Journal of atherosclerosis and thrombosis

authors： Takemura A,Ishihara A

更新日期：2017-01-01 00:00:00

abstract：AIM:It has been reported that beta-blockers (BB) reduce cardiovascular events in patients with atherosclerotic disease. However, little is known about the efficacy of these drugs in patients with critical limb ischemia (CLI). We investigated whether beta-blocker therapy affects the clinical outcomes of CLI patients. M...

journal_title：Journal of atherosclerosis and thrombosis

authors： Soga Y,Iida O,Takahara M,Hirano K,Suzuki K,Kawasaki D

更新日期：2015-01-01 00:00:00

abstract：:A number of effective drugs have been developed through animal experiments, contributing to the health of many patients. In particular, the WHHL rabbit family (WHHL rabbits and its advanced strains (coronary atherosclerosis-prone WHHL-CA rabbits and myocardial infarction-prone WHHLMI rabbits) developed at Kobe Univers...

journal_title：Journal of atherosclerosis and thrombosis

authors： Shiomi M

更新日期：2020-02-01 00:00:00

abstract：AIM:There are few data regarding associations between sleep duration and subclinical atherosclerosis in Japan. The aim of this study was to evaluate associations of self-reported sleep duration with calcification in the coronary arteries (CAC) and carotid intima media thickness (IMT) in Japanese men. METHODS:This was ...

journal_title：Journal of atherosclerosis and thrombosis

authors： Suzuki S,Arima H,Miyazaki S,Fujiyoshi A,Kadota A,Takashima N,Hisamatsu T,Kadowaki S,Zaid M,Torii S,Horie M,Murata K,Miura K,Ueshima H,SESSA Research Group.

更新日期：2018-02-01 00:00:00

abstract：AIMS:Considering that cerebral infarction (CI) may share a common etiological basis with coronary artery disease (CAD), we evaluated six CAD-related single-nucleotide polymorphisms (SNPs) on 9p21 for investigating the effect of 9p21 on CI or carotid plaque in the Chinese Han population. METHODS:Altogether, 528 patient...

journal_title：Journal of atherosclerosis and thrombosis

authors： Lu Z,Zhang Y,Maimaiti Y,Feng Y,Sun J,Zhuang J,Zeng L,Fu Y

更新日期：2015-01-01 00:00:00

abstract：AIMS:Hypertrophied hearts at autopsy often display excessive coronary artery atherosclerosis, but the histopathology of coronary arteries in hearts with and without cardiomegaly has rarely been compared. METHODS:In this study, forensic autopsies provided hearts with unexplained enlargement plus comparison specimens. R...

journal_title：Journal of atherosclerosis and thrombosis

authors： Tracy RE

更新日期：2011-01-01 00:00:00

abstract：:Although abdominal obesity or visceral obesity is considered to be one of the components of metabolic syndrome and to have an important role in a cluster of cardiovascular risks, there is no consensus about the definition and diagnostic criteria for this syndrome, probably because there is considerable disagreement ab...

journal_title：Journal of atherosclerosis and thrombosis

authors： Matsuzawa Y,Funahashi T,Nakamura T

更新日期：2011-01-01 00:00:00

abstract：AIM:Because the prevalence of hyperuricemia is lower in females than in males, the association between hyperuricemia and cardiovascular disease has been frequently reported in females. Increased serum uric acid levels are associated with the presence of cardiovascular risk factors such as hypertension, renal dysfunctio...

journal_title：Journal of atherosclerosis and thrombosis

authors： Ando K,Takahashi H,Watanabe T,Daidoji H,Otaki Y,Nishiyama S,Arimoto T,Shishido T,Miyashita T,Miyamoto T,Kubota I

更新日期：2016-08-01 00:00:00

abstract：AIMS:Small arteries can be visualized in the ocular fundus, and findings of retinopathy based on Scheie classification are often applied to evaluate the impact of hypertension and atherosclerosis. However, the relationship between damage in the large and small arteries has not been investigated sufficiently, especially...

journal_title：Journal of atherosclerosis and thrombosis

authors： Sugiura T,Dohi Y,Takagi Y,Yokochi T,Yoshikane N,Suzuki K,Tomiishi T,Nagami T,Iwase M,Takase H,Seo Y,Ohte N

更新日期：2020-11-25 00:00:00

abstract：AIM:Lipoprotein lipase protein exists in preheparin serum (preheparin LpL mass), even though lipoprotein lipase activity is rarely detected. Recent clinical studies have clarified that low preheparin LpL mass concentration is an important coronary risk factor. The aim of this study was to clarify the effect of telmisar...

journal_title：Journal of atherosclerosis and thrombosis

authors： Hitsumoto T,Takahashi M,Iizuka T,Shirai K

更新日期：2008-06-01 00:00:00

abstract：AIM:Changes in indexes of obesity, such as waist circumference (WC) and body mass index (BMI), may influence some glucose metabolism-related parameters in both obese and non-obese subjects. We have investigated the impact of changes in WC and in BMI on data related to glucose metabolism over a one-year period. METHODS...

journal_title：Journal of atherosclerosis and thrombosis

authors： Sakamoto A,Ishizaka Y,Toda E,Nagai R,Koike K,Yamakado M,Ishizaka N

更新日期：2010-12-26 00:00:00

abstract：AIM:This study aimed to examine whether cardiorespiratory fitness (CRF) is associated with arterial stiffening, evaluated using the cardio-ankle vascular index (CAVI), independent of visceral fat (VF) in middle-aged and elderly Japanese men. We also examined whether the relationship between CRF and the CAVI is modified...

journal_title：Journal of atherosclerosis and thrombosis

authors： Tanisawa K,Ito T,Sun X,Kawakami R,Oshima S,Gando Y,Cao ZB,Sakamoto S,Higuchi M

更新日期：2015-01-01 00:00:00

abstract：AIM:Ezetimibe, an inhibitor of cholesterol intestinal absorption, is a lipid lowering agent. However, anti-atherogenic effects of ezetimibe have not been fully elucidated. Therefore, the objective in this study was to clarify the vascular protective effects of ezetimibe in patients with hypercholesterolemia. METHODS:E...

journal_title：Journal of atherosclerosis and thrombosis

authors： Kurobe H,Aihara K,Higashida M,Hirata Y,Nishiya M,Matsuoka Y,Kanbara T,Nakayama T,Kinoshita H,Sugano M,Fujimoto E,Kurobe A,Sugasawa N,Kitaichi T,Akaike M,Sata M,Matsumoto T,Kitagawa T

更新日期：2011-01-01 00:00:00

abstract：AIM:Malnutrition has been identified to be an independent predictor of morbidity and mortality in patients with chronic heart failure (CHF). However, the pathophysiological mechanisms underlying this pathway remain unclear. METHODS:Nutritional screening was performed using the controlling nutritional status (CONUT) sc...

journal_title：Journal of atherosclerosis and thrombosis

authors： Nakagomi A,Kohashi K,Morisawa T,Kosugi M,Endoh I,Kusama Y,Atarashi H,Shimizu W

更新日期：2016-06-01 00:00:00

abstract：AIM:Ultrasound protocols to measure carotid intima media thickness (CIMT) differ considerably with regard to the inclusion of the number of carotid segments and angles used. Detailed information on the completeness of CIMT information is often lacking in published reports, and at most, overall percentages are presented...

journal_title：Journal of atherosclerosis and thrombosis

authors： Dogan S,Duivenvoorden R,Grobbee DE,Kastelein JJ,Shear CL,Evans GW,Visseren FL,Bots ML,Radiance 1 and 2 Study Groups.

更新日期：2010-05-01 00:00:00

abstract：:Hypertriglyceridemia is often associated with small dense low density lipoprotein (LDL), elevated remnants, and decreased high density lipoprotein (HDL)-cholesterol (C), which comprise the dyslipidemic triad. The objective of this study was to investigate the effect of fenofibrate on the lipoprotein subfraction profil...

journal_title：Journal of atherosclerosis and thrombosis

authors： Ikewaki K,Tohyama J,Nakata Y,Wakikawa T,Kido T,Mochizuki S

更新日期：2004-01-01 00:00:00

abstract：AIM:The prognostic value of homocysteine (HCY) in patients with coronary artery diseases (CAD) is still controversial. The objective of this study was to investigate whether elevated HCY level at admission predict long-term outcomes in patients after percutaneous coronary interventions (PCI) with coronary artery stenti...

journal_title：Journal of atherosclerosis and thrombosis

authors： Yeh JK,Chen CC,Hsieh MJ,Tsai ML,Yang CH,Chen DY,Chang SH,Wang CY,Lee CH,Hsieh IC

更新日期：2017-07-01 00:00:00

abstract：:We studied the association of six common polymorphisms of four genes related to lipid metabolism with serum lipid levels. We selected single-nucleotide polymorphisms (SNPs) in the genes for cholesteryl ester transfer protein (CETP), lipoprotein lipase (LPL), hepatic lipase (LIPC), and apolipoprotein CIII (APOC3), and ...

journal_title：Journal of atherosclerosis and thrombosis

authors： Arai H,Yamamoto A,Matsuzawa Y,Saito Y,Yamada N,Oikawa S,Mabuchi H,Teramoto T,Sasaki J,Nakaya N,Itakura H,Ishikawa Y,Ouchi Y,Horibe H,Egashira T,Hattori H,Shirahashi N,Kita T

更新日期：2005-01-01 00:00:00

abstract：AIM:Soluble cell adhesion molecules, such as vascular cell adhesion molecule-1 (VCAM-1), intercellular adhesion molecule-1, E-selectin, and P-selectin, have been suggested to be associated with cardiovascular disease (CVD) risk; however, the nature and magnitude of the association between VCAM-1 and CVD risk is uncerta...

journal_title：Journal of atherosclerosis and thrombosis

authors： Kunutsor SK,Bakker SJL,Dullaart RPF

更新日期：2017-08-01 00:00:00

abstract：AIM:The importance of sarcopenia in cardiovascular diseases has been recently demonstrated. This study aims to examine whether skeletal muscle mass (SMM), an important component of sarcopenia, is associated with an increased risk of poor outcome in patients after ST-segment elevation myocardial infarction (STEMI). MET...

journal_title：Journal of atherosclerosis and thrombosis

authors： Sato R,Akiyama E,Konishi M,Matsuzawa Y,Suzuki H,Kawashima C,Kimura Y,Okada K,Maejima N,Iwahashi N,Hibi K,Kosuge M,Ebina T,von Haehling S,Anker SD,Tamura K,Kimura K

更新日期：2020-12-01 00:00:00

abstract：AIM:The arterial pressure-volume index (API) and arterial velocity-pulse index (AVI) are novel measurement indices of arterial stiffness. This study was performed to examine the screening validity of the API and AVI for preclinical atherosclerosis in Japanese community-dwelling adults. METHODS:We conducted a cross-sec...

journal_title：Journal of atherosclerosis and thrombosis

authors： Yamanashi H,Koyamatsu J,Nagayoshi M,Shimizu Y,Kawashiri SY,Kondo H,Fukui S,Tamai M,Maeda T

更新日期：2018-09-01 00:00:00

abstract：AIM:We evaluated the impact of adherence to preferable behavior on serum lipid control assessed by a self-reported questionnaire in high-risk patients taking pravastatin for primary prevention of coronary artery disease. METHODS:High-risk patients taking pravastatin were followed for 2 years. Questionnaire surveys com...

journal_title：Journal of atherosclerosis and thrombosis

authors： Kitagawa Y,Teramoto T,Daida H,APPROACH-J Study group.

更新日期：2012-01-01 00:00:00

abstract：AIMS:Perilipin and adipophilin, PAT family proteins, play important roles in lipid metabolism. Although nonalcoholic fatty liver disease (NAFLD) is initiated by hepatocyte lipidation, little is known about the relationship between these proteins and hepatocellular injury. We investigated the expressions of perilipin an...

journal_title：Journal of atherosclerosis and thrombosis

authors： Fujii H,Ikura Y,Arimoto J,Sugioka K,Iezzoni JC,Park SH,Naruko T,Itabe H,Kawada N,Caldwell SH,Ueda M

更新日期：2009-01-01 00:00:00

abstract：AIM:A new antibody reacted with an epitope in Lp(a) that has undergone oxidation treatment, but is not present in native Lp(a), was developed. Thus, we determined serum oxidized Lp(a) concentration in healthy volunteers, and coronary artery disease (CAD), diabetes mellitus (DM), and hypertensive patients. METHODS:We m...

journal_title：Journal of atherosclerosis and thrombosis

authors： Morishita R,Ishii J,Kusumi Y,Yamada S,Komai N,Ohishi M,Nomura M,Hishida H,Niihashi M,Mitsumata M

更新日期：2009-08-01 00:00:00

abstract：AIM:Nocturnal intermittent hypoxia (NIH), a primary marker of obstructive sleep apnea, has increasingly been linked with cardiovascular morbidity and mortality. The purpose of this study was to investigate the association between NIH and arterial stiffness as measured according to the cardio-ankle vascular index (CAVI)...

journal_title：Journal of atherosclerosis and thrombosis

authors： Alberto EC,Tanigawa T,Maruyama K,Kawasaki Y,Eguchi E,Mori H,Yoshimura K,Tanno S,Sakurai S,Hitsumoto S,Saito I

更新日期：2014-01-01 00:00:00

abstract：:Rats with alloxan-induced diabetes developed severe atherosclerotic lesions when they were maintained on a 0.25% cholesterol diet for one year. The atheromatous changes developed at the aortic arch, appeared as early as 3 months after the start of the experiment, and increased thereafter. The diabetic rats also develo...

journal_title：Journal of atherosclerosis and thrombosis

authors： Uchida K,Takase H,Nomura Y,Nakamura Y,Igimi H,Takasu N,Kurihara H,Takeuchi N

更新日期：1994-01-01 00:00:00

abstract：AIM:To investigate the association between arterial stiffness (present with brachial-ankle pulse wave velocity (baPWV)) and metabolic syndrome (MetS) in a population-based study of middle-aged Chinese. METHODS:MetS was defined using the AHA/NHLBI criteria. A total of 1,018 subjects aged 40 years and over were recruite...

journal_title：Journal of atherosclerosis and thrombosis

authors： Lin WY,Lai MM,Li CI,Lin CC,Li TC,Chen CC,Lin T,Liu CS

更新日期：2009-04-01 00:00:00