Abstract:
:Although abdominal obesity or visceral obesity is considered to be one of the components of metabolic syndrome and to have an important role in a cluster of cardiovascular risks, there is no consensus about the definition and diagnostic criteria for this syndrome, probably because there is considerable disagreement about the location and definition of abdominal obesity or visceral obesity.In this review article, the important role of visceral fat accumulation in the development of a variety of lifestyle-related diseases is shown, including cardiovascular disease based on our clinical studies using CT scans, and the mechanism of these disorders is discussed, focusing on adipocytokines, especially adiponectin.The importance of diagnosing metabolic syndrome, in which visceral fat accumulation plays an essential role in the development of multiple risk factors, should be emphasized because lifestyle modification for the reduction of visceral fat may be very effective for the reduction of risks of this type, namely metabolic syndrome in the narrow sense.
journal_name
J Atheroscler Thrombjournal_title
Journal of atherosclerosis and thrombosisauthors
Matsuzawa Y,Funahashi T,Nakamura Tdoi
10.5551/jat.7922subject
Has Abstractpub_date
2011-01-01 00:00:00pages
629-39issue
8eissn
1340-3478issn
1880-3873pii
JST.JSTAGE/jat/7922journal_volume
18pub_type
杂志文章,评审abstract:AIMS:Statins not only reduce low-density lipoprotein (LDL) cholesterol, but also prevent the progression of kidney dysfunction. Ezetimibe, a cholesterol-absorption inhibitor, also lowers LDL cholesterol levels when added to statins; however, the effect of add-on ezetimibe on kidney function has had conflicting results....
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abstract::Cardiovascular disease constitutes the major cause of mortality in patients with chronic kidney disease. Arterial stiffness is an important contributor to the occurrence and progression of cardiovascular disease. Various risk factors, including altered hormone levels, have been suggested to be associated with arterial...
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journal_title:Journal of atherosclerosis and thrombosis
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journal_title:Journal of atherosclerosis and thrombosis
pub_type: 杂志文章,随机对照试验
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更新日期:2009-10-01 00:00:00
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更新日期:2005-01-01 00:00:00
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journal_title:Journal of atherosclerosis and thrombosis
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journal_title:Journal of atherosclerosis and thrombosis
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更新日期:2011-01-01 00:00:00
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