Conjunctival metastasis as initial sign of disseminated cutaneous melanoma.

abstract：PURPOSE:To describe the histopathologic features of Descemet's membrane (DM) obtained from Fuchs' endothelial corneal dystrophy (FECD) corneas undergoing Descemet's stripping with endothelial keratoplasty (DSEK) and to assess the presence of advanced glycation end products (AGEs) and their receptors in FECD endothelium...

journal_title：Ophthalmology

authors： Wang Z,Handa JT,Green WR,Stark WJ,Weinberg RS,Jun AS

更新日期：2007-08-01 00:00:00

abstract：:A 34-year-old white man with skin manifestations of the epidermal nevus syndrome was found to have anesthetic corneas, dry eyes, and localized opaque nodular elevations of both corneas. Similar corneal lesions, unassociated with corneal anesthesia, were found in four family members. Histology of corneal biopsies from ...

journal_title：Ophthalmology

authors： Hirst LW,Farmer ER,Green WR,Silver A,Walsh FB

更新日期：1984-02-01 00:00:00

abstract：OBJECTIVE:To assess the effectiveness of intravitreal aflibercept in patients with neovascular age-related macular degeneration (AMD) previously resistant to treatment with other anti-vascular endothelial growth factor agents. DESIGN:Prospective, open-label, noncontrolled, registered clinical trial. PARTICIPANTS:Fort...

journal_title：Ophthalmology

authors： Chang AA,Li H,Broadhead GK,Hong T,Schlub TE,Wijeyakumar W,Zhu M

更新日期：2014-01-01 00:00:00

abstract：PURPOSE:This is a pilot study to assess the use of autologous plasmin enzyme (APE) as an adjunct to vitreous surgery in eyes with advanced diabetic retinopathy. DESIGN:Prospective noncomparative interventional case series. PARTICIPANTS:Seven patients with advanced diabetic retinopathy selected at random from our prac...

journal_title：Ophthalmology

authors： Williams JG,Trese MT,Williams GA,Hartzer MK

更新日期：2001-10-01 00:00:00

abstract：BACKGROUND:Postoperative recurrence of pterygium occurs in many patients. The authors studied the recurrence rate of pterygium after administration of a single intraoperative dosage of topcial mitomycin C at the completion of pterygium excision. METHODS AND PATIENTS:Eighty-one patients underwent excision of the pteryg...

journal_title：Ophthalmology

authors： Frucht-Pery J,Siganos CS,Ilsar M

更新日期：1996-04-01 00:00:00

abstract：BACKGROUND:Opportunistic infections frequently involve the anterior and posterior segments of the eye but rarely occur in the orbit in patients with human immunodeficiency virus (HIV) infection. The authors managed eight patients with HIV and unilateral orbital infections who presented between July 1988 and March 1995....

journal_title：Ophthalmology

authors： Kronish JW,Johnson TE,Gilberg SM,Corrent GF,McLeish WM,Scott KR

更新日期：1996-09-01 00:00:00

abstract：:An experimental dog model was used to reproduce the clinical picture of bilateral arteriole and choriocapillaris occlusion from a unilateral intracarotid injection of long-acting corticosteroids combined with other drugs including lidocaine, epinephrine, and penicillin. All five known long-acting corticosteroids, when...

journal_title：Ophthalmology

authors： Wilson RS,McGrew RN,White HJ

更新日期：1978-09-01 00:00:00

abstract：PURPOSE:To determine whether scleral buckle placement at the time of primary repair of open-globe injury of the posterior segment is beneficial. DESIGN:Retrospective, comparative, nonrandomized interventional study. PARTICIPANTS:One hundred twenty-five open-globe injuries treated at the Duke University Medical Center...

journal_title：Ophthalmology

authors： Stone TW,Siddiqui N,Arroyo JG,McCuen BW 2nd,Postel EA

更新日期：2000-10-01 00:00:00

abstract：PURPOSE:To recognize discoid lupus erythematosus (DLE) as a treatable cause of chronic blepharoconjunctivitis. DESIGN:Retrospective observational case series. PARTICIPANTS:Records of 5 patients with biopsy-proven DLE were reviewed. METHODS:Clinical and pathology records were examined. MAIN OUTCOME MEASURES:Patients...

journal_title：Ophthalmology

authors： Acharya N,Pineda R 2nd,Uy HS,Foster CS

更新日期：2005-05-01 00:00:00

abstract：OBJECTIVE:This study aimed to develop a protocol to screen and monitor patients with diabetic macular thickening using optical coherence tomography (OCT), a technique for high-resolution cross-sectional imaging of the retina. DESIGN:A cross-sectional pilot study was conducted. PARTICIPANTS:A total of 182 eyes of 107 ...

journal_title：Ophthalmology

authors： Hee MR,Puliafito CA,Duker JS,Reichel E,Coker JG,Wilkins JR,Schuman JS,Swanson EA,Fujimoto JG

更新日期：1998-02-01 00:00:00

abstract：PURPOSE:To compare rates of peripheral retinal changes in Age-Related Eye Disease Study 2 (AREDS2) participants with at least intermediate age-related macular degeneration (AMD) with control subjects without intermediate age-related changes (large drusen). DESIGN:Cross-sectional evaluation of clinic-based patients enr...

journal_title：Ophthalmology

authors： Writing Committee for the OPTOS PEripheral RetinA (OPERA) study (Ancillary Study of Age-Related Eye Disease Study 2).,Domalpally A,Clemons TE,Danis RP,Sadda SR,Cukras CA,Toth CA,Friberg TR,Chew EY

更新日期：2017-04-01 00:00:00

abstract：:Specular microscopy was done on 65 long-term hard contact lens (CL) wearers and controls matched for age, sex, race, and refractive error. There was no difference in mean endothelial cell size between the two groups, although median cell area was slightly smaller in the CL group. Standard deviation and coefficient of ...

journal_title：Ophthalmology

authors： Yamauchi K,Hirst LW,Enger C,Rosenfeld J,Vogelpohl W

更新日期：1989-08-01 00:00:00

abstract：OBJECTIVE:To describe the clinical presentation, outcome, and possible underlying mechanism of aqueous misdirection after glaucoma drainage device implantation. DESIGN:Retrospective, noncomparative, interventional case series. PARTICIPANTS:Ten eyes (five primary open-angle glaucoma, four chronic angle-closure glaucom...

journal_title：Ophthalmology

authors： Greenfield DS,Tello C,Budenz DL,Liebmann JM,Ritch R

更新日期：1999-05-01 00:00:00

abstract：:Arteriohepatic dysplasia (AHD, Alagille's syndrome) is presumed to be one of the six known familial intrahepatic cholestatic syndromes, all of which present with neonatal jaundice or failure to thrive, or both. Accurate early diagnosis of the proper syndrome is important, as arteriohepatic dysplasia has a good prognos...

journal_title：Ophthalmology

authors： Puklin JE,Riely CA,Simon RM,Cotlier E

更新日期：1981-04-01 00:00:00

abstract：PURPOSE:To determine 5-year outcomes of Descemet stripping endothelial keratoplasty (DSEK) for Fuchs' endothelial corneal dystrophy (FECD). DESIGN:Prospective cohort study. PARTICIPANTS:Fifty-two eyes of 45 subjects with FECD undergoing primary DSEK. METHODS:Subjects were examined before and at fixed intervals throu...

journal_title：Ophthalmology

authors： Wacker K,Baratz KH,Maguire LJ,McLaren JW,Patel SV

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Histopathologic studies of this unusual keratitis caused by Capnocytophaga species have not been reported previously. METHODS:The authors report the light microscopic and ultrastructural findings of three patients with a distinctive necrotizing keratitis caused by an anaerobic gram-negative bacillus. In thr...

journal_title：Ophthalmology

authors： Font RL,Jay V,Misra RP,Jones DB,Wilhelmus KR

更新日期：1994-12-01 00:00:00

abstract：OBJECTIVE:This study evaluated the predictability, stability, and safety of laser in situ keratomileusis (LASIK) in myopia and myopic astigmatism. DESIGN:The study design was a prospective, unmasked, nonrandomized clinical trial. PARTICIPANTS:Participating were 25 patients with myopia (37 eyes) with astigmatism of le...

journal_title：Ophthalmology

authors： Knorz MC,Wiesinger B,Liermann A,Seiberth V,Liesenhoff H

更新日期：1998-05-01 00:00:00

abstract：OBJECTIVE:To examine the effectiveness of scleral buckling surgery for active stage 4A retinopathy of prematurity. DESIGN:Retrospective noncomparative case series. PARTICIPANTS:Eight eyes of seven infants were examined. All except one had previous peripheral ablation (cryotherapy-laser) but retinal detachment was act...

journal_title：Ophthalmology

authors： Hinz BJ,de Juan E Jr,Repka MX

更新日期：1998-10-01 00:00:00

abstract：PURPOSE:Droperidol and the new serotonin-3 antagonists are effective drugs for the prophylaxis of postoperative nausea and vomiting (PONV). The aim of this trial was to evaluate whether dolasetron could be a substitute for droperidol, because the Food and Drug Administration has required a Black Box warning on the drop...

journal_title：Ophthalmology

authors： Eberhart LH,Morin AM,Hoerle S,Wulf H,Geldner G

更新日期：2004-08-01 00:00:00

abstract：:A 21-year-old man with known Castleman's disease, a lymphoproliferative disorder with both local and systemic manifestations, presented with decreased vision in the left eye and chromatopsia. He had infiltration of the left disc and choroid with elevation of the retina, multiple bilateral depigmented areas at the leve...

journal_title：Ophthalmology

authors： Gittinger JW Jr

更新日期：1989-11-01 00:00:00

abstract：BACKGROUND:Nonarteritic anterior ischemic optic neuropathy (NAION) is a common cause of visual loss in the older population. Bilateral NAION is a well-documented entity; however, no study to date has compared the visual outcome between affected eyes. METHODS:The authors retrospectively reviewed the charts of 99 patien...

journal_title：Ophthalmology

authors： Boone MI,Massry GG,Frankel RA,Holds JB,Chung SM

更新日期：1996-08-01 00:00:00

abstract：:The effectiveness of trabeculectomy with adjunctive low-dose 5-fluorouracil (5-FU) as the initial surgical procedure in uncomplicated glaucoma was evaluated retrospectively in a consecutive series of 52 patients (mean follow-up, 18.6 +/- 11.7 mos) and 74 control subjects. The cumulative 2-year success (intraocular pre...

journal_title：Ophthalmology

authors： Liebmann JM,Ritch R,Marmor M,Nunez J,Wolner B

更新日期：1991-07-01 00:00:00

abstract：:Nodular, gray-white, central corneal opacities which extended from the subepithelial zone through the anterior four fifths of the stroma developed in a 50-year-old man with a longstanding history of hard contact lens wear for keratoconus. Results of histopathologic analysis of the corneal button obtained at the time o...

journal_title：Ophthalmology

authors： Stern GA,Knapp A,Hood CI

更新日期：1988-01-01 00:00:00

abstract：PURPOSE:To characterize the demographics of patients with dacryolithiasis and to compare patients who have canalicular concretions with patients who have lacrimal sac and duct dacryoliths. DESIGN:Comparative case series study and literature review. PARTICIPANTS:A total of 327 consecutive patients undergoing external ...

journal_title：Ophthalmology

authors： Repp DJ,Burkat CN,Lucarelli MJ

更新日期：2009-11-01 00:00:00

abstract：PURPOSE:To evaluate safety and efficacy of an intracorneal inlay for the correction of hyperopia. DESIGN:A prospective, nonrandomized, noncomparative, 2-center study. PARTICIPANTS:Thirty-four hyperopic eyes were implanted with a hydrogel intracorneal inlay (Permavision, Anamed, Lake Forest, CA). Preoperative hyperopi...

journal_title：Ophthalmology

authors： Mulet ME,Alio JL,Knorz MC

更新日期：2009-08-01 00:00:00

abstract：OBJECTIVE:To characterize optic nerve head (ONH) anatomy related to the clinical optic disc margin with spectral domain-optical coherence tomography (SD-OCT). DESIGN:Cross-sectional study. PARTICIPANTS:Patients with open-angle glaucoma with focal, diffuse, and sclerotic optic disc damage, and age-matched normal contr...

journal_title：Ophthalmology

authors： Reis AS,Sharpe GP,Yang H,Nicolela MT,Burgoyne CF,Chauhan BC

更新日期：2012-04-01 00:00:00

abstract：PURPOSES:To evaluate submacular surgery for the management of subfoveal choroidal neovascularization in punctate inner choroidopathy, to describe the histopathology and ultrastructure of the excised subretinal tissue, and to propose a staging system that characterizes the development of choroidal neovascularization wit...

journal_title：Ophthalmology

authors： Olsen TW,Capone A Jr,Sternberg P Jr,Grossniklaus HE,Martin DF,Aaberg TM Sr

更新日期：1996-12-01 00:00:00

abstract：PURPOSE:A study was performed to determine if diabetic subjects who fail to respond to initial panretinal photocoagulation with regression of retinopathy risk factors do better with supplemental panretinal photocoagulation. METHODS:Thirty-five patients with 3 or more retinopathy risk factors who failed to respond to p...

journal_title：Ophthalmology

authors： Doft BH,Metz DJ,Kelsey SF

更新日期：1992-11-01 00:00:00

abstract：OBJECTIVE:To assess the factors that can predict the success of external needle revision of failing blebs. DESIGN:Retrospective, nonrandomized, comparative case series. PARTICIPANTS:Forty-nine eyes of 43 patients who underwent a needle revision of a filtration bleb with 5-fluourouracil (5-FU) by one physician (SVLB) ...

journal_title：Ophthalmology

authors： Hawkins AS,Flanagan JK,Brown SV

更新日期：2002-04-01 00:00:00

abstract：:Long-term follow-up was recorded on the visual fields of 251 patients with chronic open-angle glaucoma and 826 patients with ocular hypertension. Observation periods exceeded ten years for 73 patients with manifest glaucoma. Initial glaucomatous defects appeared in 98 eyes of 72 patients while under continuous observa...

journal_title：Ophthalmology

authors： Hart WM Jr,Becker B

更新日期：1982-03-01 00:00:00