Abstract：
BACKGROUND:Nonarteritic anterior ischemic optic neuropathy (NAION) is a common cause of visual loss in the older population. Bilateral NAION is a well-documented entity; however, no study to date has compared the visual outcome between affected eyes. METHODS:The authors retrospectively reviewed the charts of 99 patients with diagnoses of NAION over 3 1/2 years. In the 23 patients with bilateral involvement, 16 were included in the study for analysis of final visual outcome between affected eyes. Snellen acuity, Ishihara color plates, and Humphrey automated perimetry were evaluated as the parameters of visual function. Descriptive analysis of the outcome between affected eyes for each parameter is presented as a frequency distribution of pre-defined groups. Statistical significance is established using nonparametric tests. RESULTS:Bilateral NAION was found in 23% (23/99) of the patients studied. The authors identified a high percent agreement between eyes with regard to visual acuity (81% within 3 Snellen lines), color vision (69% within 3 plates), and Humphrey visual field (75% within 5 decibels of mean deviation). Additionally, there was a statistically significant correlation between affected eyes for all three visual parameters: visual acuity (P = 0.043), color vision (P = 0.001), and Humphrey visual field (P = 0.039). CONCLUSION:The authors found a high percent agreement and statistically significant correlation in final outcome between affected eyes of patients with bilateral NAION for visual acuity, color vision, and visual field loss. With a larger series, it may be possible to predict the visual outcome of the second affected eye based on the parameters of the first eye.
journal_name
Ophthalmologyjournal_title
Ophthalmologyauthors
Boone MI,Massry GG,Frankel RA,Holds JB,Chung SMdoi
10.1016/s0161-6420(96)30519-8subject
Has Abstractpub_date
1996-08-01 00:00:00pages
1223-8issue
8eissn
0161-6420issn
1549-4713pii
S0161-6420(96)30519-8journal_volume
103pub_type
杂志文章相关文献
OPHTHALMOLOGY文献大全abstract：PURPOSE:To report the long-term results of corneal collagen cross-linking (CXL) in ectasia after LASIK and photorefractive keratectomy (PRK). DESIGN:Retrospective, interventional cases series. PARTICIPANTS:Twenty-six eyes of 26 patients (18 male, 8 female) with postoperative ectasia after LASIK (23 eyes) and PRK (3 e...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ophtha.2012.12.027
更新日期：2013-07-01 00:00:00
abstract：OBJECTIVE:To identify risk factors associated with failure of anatomic reattachment in primary rhegmatogenous retinal detachment repair. DESIGN:Nonrandomized, multicenter, collaborative study. PARTICIPANTS:Primary procedures for 7678 rhegmatogenous retinal detachments reported by 176 surgeons from 48 countries. METH...
journal_title：Ophthalmology
pub_type： 杂志文章,多中心研究
doi：10.1016/j.ophtha.2014.03.012
更新日期：2014-09-01 00:00:00
abstract：PURPOSE:To investigate the frequency of sneezing among patients receiving intravenous sedation and periocular local anesthetic for oculoplastic procedures in a single center. To identify potential risk factors involved. DESIGN:Prospective, consecutive, interventional case series in a single tertiary-referral oculoplas...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ophtha.2009.09.007
更新日期：2010-05-01 00:00:00
abstract：TOPIC:Macular parameters have been proposed as an alternative to retinal nerve fiber layer (RNFL) parameters to diagnose glaucoma. Comparing the diagnostic accuracy of macular parameters, specifically the ganglion cell complex (GCC) and ganglion cell inner plexiform layer (GCIPL), with the accuracy of RNFL parameters f...
journal_title：Ophthalmology
pub_type： 杂志文章,评审
doi：10.1016/j.ophtha.2015.12.041
更新日期：2016-05-01 00:00:00
abstract：BACKGROUND:Beta-radiation has been used since 1950 as a postoperative measure to reduce the recurrence of pterygia. Scleral necrosis has been a major complication after radiotherapy that has led to perforation of the globe, endophthalmitis, and visual loss in some cases. METHOD:A patient is presented in whom scleral n...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/s0161-6420(95)30914-1
更新日期：1995-07-01 00:00:00
abstract：:The accurate clinical diagnosis of benign mixed tumors of the lacrimal gland is imperative for proper therapeutic management. Although benign mixed tumors of the orbital portion of the lacrimal gland have an established identity, those tumors arising in the palpebral lobe are unusual. Four patients with benign mixed t...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/s0161-6420(90)32572-1
更新日期：1990-04-01 00:00:00
abstract：OBJECTIVE:To compare the long-term efficacy of intraoperative 5-fluorouracil (5-FU) and mitomycin C (MMC) in primary trabeculectomy. DESIGN:Comparative case series and extension of a prospective, randomized controlled trial. PARTICIPANTS:One hundred fifteen eyes of 103 subjects undergoing primary trabeculectomy with ...
journal_title：Ophthalmology
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.ophtha.2008.08.009
更新日期：2009-02-01 00:00:00
abstract：PURPOSE:The purpose of the study is to investigate diagnostic criteria and treatment methods for patients with congenital periodic alternating nystagmus (PAN). METHODS:A retrospective analysis was performed of clinical findings and serial eye movement recordings of patients with congenital PAN. Eighteen patients obser...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/s0161-6420(97)30206-1
更新日期：1997-06-01 00:00:00
abstract：OBJECTIVE:To compare the visual outcome, neodymium:YAG (Nd:YAG) capsulotomy rates, and percentage of posterior capsular opacification (PCO) seen with polymethylmethacrylate (PMMA), silicone, and polyacrylic intraocular lens implants 3 years after surgery. DESIGN:Randomized, prospective trial. PARTICIPANTS:Ninety eyes...
journal_title：Ophthalmology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/S0161-6420(99)90047-7
更新日期：1999-01-01 00:00:00
abstract：:The first 112 consecutive eyes (75 patients) to undergo four-incision radial keratotomy (RK) performed by four surgeons were evaluated retrospectively. The preoperative myopia (spherical equivalent) ranged from -1.12 to -7.00 D (95% between -1.12 and -4.25 D). The preoperative uncorrected visual acuity was 20/100 or w...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/s0161-6420(86)33669-8
更新日期：1986-06-01 00:00:00
abstract：PURPOSE:To investigate side effects seen with this formulation and to search for evidence of effectiveness after a single intravitreal injection of IBI-20089 in eyes with cystoid macular edema (CME) secondary to retinal vein occlusion. DESIGN:Prospective, phase 1 clinical trial. PARTICIPANTS:Ten patients with chronic...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ophtha.2010.12.029
更新日期：2011-07-01 00:00:00
abstract：PURPOSE:To report the success rate of endoscopically assisted balloon dacryoplasty (EADCP) for treatment of acquired incomplete nasolacrimal duct obstructions (NLDOs). DESIGN:Retrospective, noncomparative case series. PARTICIPANTS:Records of patients treated for incomplete NLDOs with EADCP by one of the authors (WLW)...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ophtha.2003.06.013
更新日期：2004-03-01 00:00:00
abstract：OBJECTIVES:To assess the clinical value of retinal or choroidal biopsy in establishing a definitive diagnosis directing subsequent management and to assess the risk involved in such surgery. DESIGN:Retrospective noncomparative interventional case series. PARTICIPANTS:Thirteen patients with uveitis of suspected malign...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ophtha.2002.10.002
更新日期：2004-03-01 00:00:00
abstract：PURPOSE:To determine the association between complement factor H (CFH) polymorphism T1277C (tyrosine-402 --> histidine-402) and phenotypic variations of age-related macular degeneration (AMD). DESIGN:Cross-sectional observational study. PARTICIPANTS:Subjects with dry or wet AMD and a control population consisting of ...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ophtha.2006.10.035
更新日期：2007-07-01 00:00:00
abstract：:The Prospective Evaluation of Radial Keratotomy (PERK) study is a nine-center clinical trial of a standardized technique of radial keratotomy in 435 patients who had simple myopia with a preoperative refractive error between -2.00 and -8.00 diopters (D). The authors report results for one eye of each patient. The surg...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/s0161-6420(87)80021-0
更新日期：1987-10-01 00:00:00
abstract：OBJECTIVE:To report cases of Avellino corneal dystrophy (ACD) exacerbated by LASIK for myopia. DESIGN:Retrospective, noncomparative, interventional case series and review of the literature. PARTICIPANTS:Seven patients. INTERVENTION:Six patients with exacerbation of granular corneal deposits after LASIK were examined...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ophtha.2003.06.026
更新日期：2004-03-01 00:00:00
abstract：PURPOSE:Heightened public awareness about glaucoma may increase the chance of identifying undetected cases. To ascertain determinants of glaucoma awareness, we surveyed a population visiting a general eye clinic. DESIGN:Cross-sectional study. PARTICIPANTS:1197 general eye clinic patients and their companions. METHOD...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/s0161-6420(99)00076-7
更新日期：2000-02-01 00:00:00
abstract：OBJECTIVE:To evaluate trend-type analyses to judge the progression of visual field damage (VFD) of glaucoma in terms of ratios of making judgments of progression and specificity, and to report a new method. DESIGN:Retrospective analysis of visual field (VF) results of actual glaucoma cases and those simulated by compu...
journal_title：Ophthalmology
pub_type： 杂志文章,多中心研究
doi：10.1016/j.ophtha.2004.06.025
更新日期：2004-11-01 00:00:00
abstract：PURPOSE:To identify systemic factors associated with the development of central serous chorioretinopathy (CSCR). DESIGN:Retrospective, case-control study. PARTICIPANTS AND CONTROLS:312 cases and 312 controls. RESULTS:By use of a multivariate analysis, the previously described risk factors, systemic steroid use (odds...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ophtha.2003.09.024
更新日期：2004-02-01 00:00:00
abstract：:Five hundred forty-seven reports of adverse reactions to timolol maleate received by the National Registry for Drug-induced Ocular Side Effects during an eleven-month period were reviewed. Approximately half the reports concerned systemic reactions affecting the cardiac, pulmonary, central nervous, gastrointestinal, a...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/s0161-6420(80)35215-9
更新日期：1980-05-01 00:00:00
abstract：OBJECTIVE:The purpose of the study is to examine the association between cardiovascular disease and its risk factors and the incidence of age-related maculopathy. PARTICIPANTS:A population of 3583 adults (range, 43-86 years of age at baseline) living in Beaver Dam, Wisconsin, was studied at baseline and 5 years later....
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/s0161-6420(97)30023-2
更新日期：1997-11-01 00:00:00
abstract：OBJECTIVE:The number of scientific publications is often used to measure scientific achievement. This practice can motivate unethical conduct, such as redundant or duplicate publications, defined as publication of the same scientific contents in more than 1 journal. The aim of this study was to estimate the amount of r...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ophtha.2003.09.029
更新日期：2004-05-01 00:00:00
abstract：PURPOSE:To understand the impact of deep learning diabetic retinopathy (DR) algorithms on physician readers in computer-assisted settings. DESIGN:Evaluation of diagnostic technology. PARTICIPANTS:One thousand seven hundred ninety-six retinal fundus images from 1612 diabetic patients. METHODS:Ten ophthalmologists (5 ...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ophtha.2018.11.016
更新日期：2019-04-01 00:00:00
abstract：:Two cases of carcinoma metastatic to the eyelid are described. The first was derived from a lung primary diagnosed two months prior and presented as a solitary tender mass mimicking an acutely inflamed recurrent chalazion. The second case was the initial manifestation of a stomach carcinoma, presenting as a solitary p...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/s0161-6420(85)34072-1
更新日期：1985-01-01 00:00:00
abstract：:Eyes undergoing routine intracapsular cataract extraction (without alpha-chymotrypsin) often experience marked ocular hypertension in the first six hours after surgery. We conducted a randomized, prospective, double-blind study to determine if timolol maleate would prevent this increase in pressure. Thirty-five eyes u...
journal_title：Ophthalmology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/s0161-6420(81)35053-2
更新日期：1981-03-01 00:00:00
abstract：:Ten eyes of eight patients with open-angle glaucoma (OAG) had neodymium (Nd):YAG trabeculopuncture performed in an investigational protocol as an alternative to surgical intervention. In each, at four to six sites in the mid-trabecular meshwork, three to six superimposed applications were made (2 to 6 mJ). In four of ...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/s0161-6420(85)33932-5
更新日期：1985-07-01 00:00:00
abstract：:Sixty-two cases of corneal amyloidosis were studied. The median age of the 48 men and 14 women was 66 years. The patients had bilateral, diffuse corneal opacity extending to the limbus and severe visual impairment. The corneal condition was not familial. Advanced stages of trachoma were present in all individuals. Cli...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/s0161-6420(89)32765-5
更新日期：1989-08-01 00:00:00
abstract：PURPOSE:To describe the results from a statewide preschool vision screening program using the MTI PhotoScreener (Medical Technology and Innovations, Inc., Cedar Falls, IA). DESIGN:Cross-sectional study. PARTICIPANTS:A total of 15,059 children aged 6 to 47 months enrolled in childcare and preschool settings throughout...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/s0161-6420(00)00298-0
更新日期：2000-09-01 00:00:00
abstract：:Granulomatous uveitis has infrequently been described as a manifestation of the autoimmune phenomena of multiple sclerosis (MS). The authors describe six cases of anterior granulomatous uveitis in patients with MS. All six patients had features of iridocyclitis and three patients had features of periphlebitis, which w...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/s0161-6420(91)32324-8
更新日期：1991-02-01 00:00:00
abstract：BACKGROUND:Oral trans-retinoic acid has recently been shown to be an effective treatment modality for acute promyelocytic leukemia. This type of drug differs from traditional tumoricidal agents by promoting differentiation of the malignant, immature cells. METHODS:The authors describe a patient with optic nerve infilt...
journal_title：Ophthalmology
pub_type： 杂志文章
doi：10.1016/s0161-6420(92)31783-x
更新日期：1992-09-01 00:00:00
