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Prophylactic timolol for the prevention of high intraocular pressure after cataract extraction. A randomized, prospective, double-blind trial.

Abstract：

:Eyes undergoing routine intracapsular cataract extraction (without alpha-chymotrypsin) often experience marked ocular hypertension in the first six hours after surgery. We conducted a randomized, prospective, double-blind study to determine if timolol maleate would prevent this increase in pressure. Thirty-five eyes undergoing routine cataract extraction were given a drop of either timolol 0.5% or placebo twice before and twice after surgery. Nine (56.3%) of 16 control eyes and 2 (10.5%) of 19 timolol-treated eyes had pressures above 30 mm Hg at six hours after surgery (P less than 0.025). Thus, prophylactic timolol 0.5% can substantially reduce the incidence of severe early postoperative ocular hypertension.

journal_name

Ophthalmology

journal_title

Ophthalmology

authors

Haimann MH,Phelps CD

doi

10.1016/s0161-6420(81)35053-2

subject

Has Abstract

pub_date

1981-03-01 00:00:00

pages

233-8

issue

3

eissn

0161-6420

issn

1549-4713

pii

S0161-6420(81)35053-2

journal_volume

88

pub_type

临床试验,杂志文章,随机对照试验

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