Abstract:
:A computer program designed according to the needs of clinical investigators has recently been implemented. This ambitious undertaking allows the ophthalmologist direct interfacing and control over all his data, presently 3,252 diabetic patient records, and thus harnesses his hypothesis-testing intuitions with the memory, speed, and flexibility of modern-day computers. There are three program modes: QUERY, a disease-independent language by which the clinician selects his population; SELECT, the actual computer selection, and DISPLAY: where general statistical maneuvers, relationships among disease parameters, ancillary data compilations, and printouts are performed. Being computer-independent and disease-independent, and adaptable to most needs of clinical investigators, this computer program brings a refreshingly new approach to the study of disease.
journal_name
Ophthalmologyjournal_title
Ophthalmologyauthors
Franks EP,Kasprzyk JS,McMeel JWdoi
10.1016/s0161-6420(81)34974-4subject
Has Abstractpub_date
1981-07-01 00:00:00pages
624-9issue
7eissn
0161-6420issn
1549-4713pii
S0161-6420(81)34974-4journal_volume
88pub_type
杂志文章相关文献
OPHTHALMOLOGY文献大全abstract::Immunohistochemical staining analysis using monoclonal antibodies was performed on 107 recipient corneas removed at graft. There were significantly more infiltrating cells bearing one or more of the leukocyte-common antigen, class II major histocompatibility complex antigens, various myeloid-lineage markers, and a per...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(89)32949-6
更新日期:1989-01-01 00:00:00
abstract:PURPOSE:To describe the clinical characteristics of and risk factors for the development of optic neuropathy after pars plana vitrectomy (PPV) for macula-sparing primary rhegmatogenous retinal detachment (RRD) repair. DESIGN:Retrospective case-control study. PARTICIPANTS:Seven patients who underwent PPV for macula-sp...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2012.06.002
更新日期:2012-11-01 00:00:00
abstract::A temporary apposition of retina and choroid has been created during retinal detachment surgery by injection of sodium hyaluronate into the suprachoroidal space in 14 patients. The iatrogenic choroidal detachment lasts at least seven to ten days, allowing adequate time for retinopexy to permanently seal the retinal ho...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(86)33553-x
更新日期:1986-11-01 00:00:00
abstract::Fluorescein angiography is an application of the physical phenomenon of fluorescence, which is phosphorescence in which the quantum mechanical decay curve is so rapid that it appears instantaneous, and it consequently has no afterglow. Sodium fluorescein is excited by light energy between 465 and 490 nm, and it decays...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(86)33521-8
更新日期:1986-12-01 00:00:00
abstract:OBJECTIVE:To compare the effect of bimatoprost and the fixed combination of latanoprost and timolol (LTFC) on 24-hour mean intraocular pressure (IOP) after patients are switched from a nonfixed combination of latanoprost and timolol. DESIGN:Randomized, double-masked, multicenter clinical trial. PARTICIPANTS:Two hundr...
journal_title:Ophthalmology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/j.ophtha.2007.01.025
更新日期:2007-12-01 00:00:00
abstract::The optic discs of eight normal subjects were photographed on three separate visits under widely varying conditions. Each photograph was scanned by a television camera, converted to digital form, and then analyzed using computer image analysis techniques. The computer was programmed to delineate the boundary around th...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(85)34057-5
更新日期:1985-02-01 00:00:00
abstract:BACKGROUND:Although allergic fungal sinusitis is a relatively common, noninvasive form of paranasal sinus mycosis, and despite frequent orbital involvement, there have been few reports of this condition in the ophthalmic literature. METHODS:Two cases of allergic fungal sinusitis having orbital symptoms are described. ...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(97)30054-2
更新日期:1997-12-01 00:00:00
abstract:OBJECTIVE:To describe the successful treatment and long-term outcomes of primary ocular surface squamous neoplasia (OSSN) with topical interferon alfa-2b or surgical excision. DESIGN:Retrospective, comparative, interventional case series. PARTICIPANTS:Twenty-nine consecutive patients with OSSN never before treated. ...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2008.01.006
更新日期:2008-08-01 00:00:00
abstract:PURPOSE:To compare the efficacy and safety of fibrin glue and suturing for attaching conjunctival autografts among patients undergoing pterygium excision. DESIGN:Prospective, randomized, interventional case series. PARTICIPANTS:Twenty-two patients undergoing excision of primary pterygium. METHODS:A superior conjunct...
journal_title:Ophthalmology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/j.ophtha.2004.08.028
更新日期:2005-04-01 00:00:00
abstract::An analysis of acute contact lens-related complications, with particular emphasis on severe microbial keratitis, was undertaken at the Department of Ophthalmology, Sahlgren's Hospital in Gothenburg. A total of 224 contact lens wearers presented with acute complications over a 2-year period (1981-1982). The lowest inci...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(87)33513-4
更新日期:1987-01-01 00:00:00
abstract::Hidradenoma papilliferum is derived from apocrine sweat glands and was originally described as a tumor located in the anogenital area. The authors recently examined a 78-year-old man with a hidradenoma papilliferum at the margin of the upper eyelid. While the tumor was located in the dermis, serial sections showed a c...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(90)32373-4
更新日期:1990-12-01 00:00:00
abstract:OBJECTIVE:The purpose of the study is to determine safety and efficacy outcomes of excimer laser photorefractive keratectomy (PRK) for the treatment of mild-to-moderate myopia. DESIGN:A prospective, multicenter, phase III clinical trial. PARTICIPANTS:A total of 701 eyes of 701 patients were entered in the study; 612 ...
journal_title:Ophthalmology
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1016/s0161-6420(97)30073-6
更新日期:1997-10-01 00:00:00
abstract::The first 290 consecutive eyes (192 patients) to undergo radial keratotomy by one surgeon were evaluated prospectively. All had had complete preoperative evaluation and 269 (93%) were examined one or more years after surgery. Preoperatively, all patients except one had worse than 20/100 uncorrected visual acuity, 65% ...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(84)34264-6
更新日期:1984-05-01 00:00:00
abstract::Conventional teaching states that the spiral of Tillaux marks the location of the ora serrata. On literature review, no source for this was found. This study explores this anatomic relationship. In 20 cadaver eyes, narrow-gauge needles were placed penetrating the center of each rectus muscle insertion, and distance to...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(89)32866-1
更新日期:1989-04-01 00:00:00
abstract:BACKGROUND:The Enhanced Vision Screening Program is a population-based vision screening program that has, at present, examined 59,782 children. Its main goal is to detect amblyopia, strabismus, and high refractive errors. An average of 11,910 4 1/2- to 5 1/2-year-old children are screened yearly. The current study dete...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(92)31865-2
更新日期:1992-06-01 00:00:00
abstract:OBJECTIVE:This study aimed to investigate the influence of disc neovascularization on the outcome of vitreous surgery for tractional retinal detachment (TRD) after branch retinal vein occlusion (BRVO). DESIGN:The study design was a retrospective case series. PARTICIPANTS:Twenty-two eyes of 22 patients who had undergo...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/S0161-6420(98)93021-4
更新日期:1998-03-01 00:00:00
abstract:OBJECTIVE:To evaluate the change in intraocular pressure (IOP) in subjects with Graves' orbitopathy (GO) after orbital decompression, strabismus surgery, and orbital radiation. DESIGN:Retrospective case review. METHODS:The charts of 172 consecutive subjects from the Neuro-ophthalmology Service at Wills Eye Hospital (...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(00)00477-2
更新日期:2001-01-01 00:00:00
abstract:PURPOSE:The purpose of this study was to characterize the contemporary clinical presentation and treatment results of patients with dislocated intraocular lenses (IOLs). DESIGN:Retrospective, noncomparative, single-surgeon interventional case series. PARTICIPANTS:Two hundred eighty-four eyes of 277 patients operated ...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2008.04.016
更新日期:2008-10-01 00:00:00
abstract:PURPOSE:Geographic atrophy (GA) may cause significant compromise of visual function, even when there still is good visual acuity (VA), because of parafoveal scotomas and foveal function abnormalities antedating visible atrophy. This study evaluates the visual function abnormalities at baseline and the 2-year worsening ...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(97)30079-7
更新日期:1997-10-01 00:00:00
abstract:TOPIC:The incidence and morbidity of herpes zoster (HZ) and HZ ophthalmicus (HZO), and the potential impact of varicella vaccine on their epidemiology. CLINICAL RELEVANCE:Herpes zoster affects 20% to 30% of the population at some point in their lifetime; approximately 10% to 20% of these individuals will have HZO. ME...
journal_title:Ophthalmology
pub_type: 杂志文章,评审
doi:10.1016/j.ophtha.2007.10.009
更新日期:2008-02-01 00:00:00
abstract:PURPOSE:To evaluate the performance of retinal specialists in detecting retinal fluid presence in spectral domain OCT (SD-OCT) scans from eyes with age-related macular degeneration (AMD) and compare performance with an artificial intelligence algorithm. DESIGN:Prospective comparison of retinal fluid grades from human ...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2020.06.038
更新日期:2021-01-01 00:00:00
abstract:PURPOSE:Posterior vitreous detachment (PVD) plays an important role in vitreoretinal interface disorders. Historically, observations of PVD using OCT have been limited to the macular region. The purpose of this study is to image the wide-angle vitreoretinal interface after PVD in normal subjects using montaged OCT imag...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2018.02.039
更新日期:2018-09-01 00:00:00
abstract::The objective of the study is to present evidence that some people with 20/200 visual acuity and a field of vision greater than 120 degrees can drive safely in the daytime at a speed of not more than 40 mph. Eight individuals with 20/200 visual acuity (legally blind) were tested for the distance at which they could re...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(89)32704-7
更新日期:1989-10-01 00:00:00
abstract:PURPOSE:This study estimates the prevalence of common visual disorders (amblyopia, strabismus, refractive errors) in a group of inner-city school children. In addition, the study addresses the issue of access to care for vision-screening programs, specifically for children with recognized difficulties in obtaining rout...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(96)30753-7
更新日期:1996-01-01 00:00:00
abstract::Preoperative and postoperative corneascope photographs of 368 myopic patients undergoing radial keratotomy in the Prospective Evaluation of Radial Keratotomy (PERK) study were optically scanned and digitized. A high-resolution scanning system was developed in order to quantify the preoperative and postoperative cornea...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(88)33179-9
更新日期:1988-03-01 00:00:00
abstract:PURPOSE:To describe the authors' 5-year experience of the 2-incision push-pull (TIPP) technique for pediatric anterior and posterior capsulorrhexis formation. DESIGN:Retrospective descriptive study over a 5-year period. PARTICIPANTS:A total of 84 eyes of 63 patients who had undergone cataract surgery in 1 center. ME...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2006.03.057
更新日期:2006-08-01 00:00:00
abstract:BACKGROUND:Polyarteritis nodosa is a necrotizing vasculitis affecting medium and small-sized arteries throughout the body, including ocular tissues. Untreated polyarteritis nodosa carries a very poor prognosis. Treatment with steroids increases the 5-year survival to 48%, whereas addition of cytotoxic immunosuppressive...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(93)31405-3
更新日期:1993-12-01 00:00:00
abstract::Twelve patients with hypereosinophilic syndrome were studied to determine the frequency and type of eye involvement in this systemic disease. Four patients (33%) had visual symptoms, including blurred vision in one or both eyes, and one patient had an episode of complete blindness following cardiac surgery. Five patie...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(82)34625-4
更新日期:1982-12-01 00:00:00
abstract:OBJECTIVE:To measure accuracy and reliability of the computer-based Retinal Image Multiscale Analysis (RISA) system compared with those of recognized retinopathy of prematurity (ROP) experts, for plus disease diagnosis. DESIGN:Evaluation of diagnostic test or technology. PARTICIPANTS:Eleven recognized ROP experts and...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2007.10.006
更新日期:2007-12-01 00:00:00
abstract:PURPOSE:To evaluate the effect of dopaminergic medication and deep brain stimulation on ocular function in Parkinson's disease (PD) and to measure vision-related quality of life in subjects with PD. DESIGN:Prospective, comparative case series. PARTICIPANTS AND CONTROLS:Twenty-seven PD and 16 control subjects were rec...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2011.06.040
更新日期:2012-01-01 00:00:00