Abstract:
:Five hundred forty-seven reports of adverse reactions to timolol maleate received by the National Registry for Drug-induced Ocular Side Effects during an eleven-month period were reviewed. Approximately half the reports concerned systemic reactions affecting the cardiac, pulmonary, central nervous, gastrointestinal, and dermatologic systems. Most serious were depression, anxiety, and confusion; bradycardia and arrhythmias; and pulmonary airway obstruction. Half of the ocular side effects concerned external ocular disease, of which superficial punctate keratitis and corneal anesthesia were the most remarkable. Ten percent of the reports described a visual disturbance which, in many cases, was not associated with refractive error.
journal_name
Ophthalmologyjournal_title
Ophthalmologyauthors
Van Buskirk EMdoi
10.1016/s0161-6420(80)35215-9subject
Has Abstractpub_date
1980-05-01 00:00:00pages
447-50issue
5eissn
0161-6420issn
1549-4713pii
S0161-6420(80)35215-9journal_volume
87pub_type
杂志文章相关文献
OPHTHALMOLOGY文献大全abstract:PURPOSE:To determine the outcome of a reduced amount of medial rectus (MR) muscle recession in esotropes with cerebral palsy (CP) and to compare the surgical response with that of normal controls. DESIGN:Retrospective cohort study. PARTICIPANTS:Thirty esotropes with CP and 60 age-matched esotropes without CP who unde...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2012.09.018
更新日期:2013-04-01 00:00:00
abstract:PURPOSE:The authors attempt to establish a relation between hard contact lens wear and upper eyelid ptosis. METHODS:This study consists of two parts. In the first part, the authors compare the unilateral or bilateral ptosis that developed during hard contact lens wear in 17 patients with the involutional ptosis that d...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(92)31725-7
更新日期:1992-12-01 00:00:00
abstract:PURPOSE:To review the clinical features and management of patients with intraorbital foreign bodies. DESIGN:Noncomparative interventional case series. PATIENTS AND METHOD:Forty patients seen at two regional orbital surgery departments with intraorbital foreign bodies were reviewed. MAIN OUTCOME MEASURES:Visual acuit...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(01)00982-4
更新日期:2002-03-01 00:00:00
abstract:PURPOSE:To evaluate outcomes of bilateral cataract surgery in children aged 7 to 24 months and compare rates of adverse events (AEs) with other Toddler Aphakia and Pseudophakia Study (TAPS) registry outcomes. DESIGN:Retrospective clinical study at 10 Infant Aphakia Treatment Study (IATS) sites. Statistical analyses co...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2020.07.020
更新日期:2021-02-01 00:00:00
abstract::Rhabdomyosarcoma is the most common malignant orbital tumor of childhood. It has twice been reported to arise within the globe from the iris. In addition, teratoid medulloepithelioma, a tumor arising from the ciliary epithelium, can contain a rhabdomyoblastic component, often in combination with other heteroplastic el...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(90)32386-2
更新日期:1990-11-01 00:00:00
abstract:OBJECTIVE:Corneal and ocular wavefront aberrations were recorded together with clinical examination results and patient-reported vision-related quality-of-life evaluation results to define the relevance of dynamic optical analysis of the eye in dry eye disease (DED). DESIGN:Prospective and comparative clinical study. ...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2012.03.004
更新日期:2012-09-01 00:00:00
abstract:PURPOSE:To evaluate changes in posterior corneal curvature as a possible cause of the hyperopic refractive shift observed after Descemet's stripping automated endothelial keratoplasty (DSAEK). DESIGN:Prospective, noncomparative, interventional case series. PARTICIPANTS:Thirty-four eyes of 29 patients with Fuchs' endo...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2009.04.035
更新日期:2009-09-01 00:00:00
abstract:PURPOSE:To evaluate the relationship between retinal sensitivity and the photoreceptor inner segment/outer segment (IS/OS) layer status in patients with diabetic macular edema (DME). DESIGN:Cross-sectional study. PARTICIPANTS:Twenty-five adult patients (37 eyes) diagnosed with DME and managed at the Wilmer Eye Instit...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2012.12.003
更新日期:2013-06-01 00:00:00
abstract:OBJECTIVES:To determine whether the incidence and severity of retinopathy of prematurity (ROP) differs between infants conceived naturally and those born after assisted conception, and to analyze the impact of singleton versus multiple gestation on ROP. DESIGN:Comparative case series. PARTICIPANTS:The study group con...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2006.11.010
更新日期:2007-02-01 00:00:00
abstract:PURPOSE:To investigate the anatomic relation between the optic nerve and the adjacent intracranial internal carotid artery (ICA) in patients with unexplained optic neuropathy. METHODS:Coronal magnetic resonance images (MRIs) of 20 patients with unexplained optic neuropathy and 20 age-matched controls were evaluated wi...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(96)30664-7
更新日期:1996-03-01 00:00:00
abstract:PURPOSE:To perform a detailed clinical, psychophysical, and molecular assessment of members of 4 families with an unusual X-linked cone dysfunction syndrome associated with myopia. PARTICIPANTS:Affected and unaffected members of 4 British nonconsanguineous families. METHODS:Subjects underwent both detailed clinical e...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2005.02.021
更新日期:2005-08-01 00:00:00
abstract:OBJECTIVE:To report cases of Avellino corneal dystrophy (ACD) exacerbated by LASIK for myopia. DESIGN:Retrospective, noncomparative, interventional case series and review of the literature. PARTICIPANTS:Seven patients. INTERVENTION:Six patients with exacerbation of granular corneal deposits after LASIK were examined...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2003.06.026
更新日期:2004-03-01 00:00:00
abstract::A retrospective evaluation of 100 patients who wore disposable extended-wear contact lenses is presented. The patients were selected at random and were fitted with one of three lens brands approved for extended wear. There were 37 males and 63 females in the study. The mean age was 40.1 years (range, 14 to 76 years). ...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(91)32068-2
更新日期:1991-11-01 00:00:00
abstract::Twenty-three patients who underwent penetrating keratoplasty were evaluated preoperatively for potential retinal acuity utilizing the Randwal Laser Interferometer and the Mentor Potential Acuity Meter. When compared with Snellen visual acuity during the early postoperative period (1-6 months), both instruments were us...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(84)34172-0
更新日期:1984-10-01 00:00:00
abstract::This article discusses the experience of progressing from a young ophthalmic resident to a full-time professional and, ultimately, to service on the American Board of Ophthalmology. ...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2016.06.013
更新日期:2016-09-01 00:00:00
abstract:PURPOSE:To show that chiasmal hypoplasia or aplasia need not be an isolated developmental anomaly and to examine the spectrum of associated clinical findings to explore the possibility that these patients may represent a phenotypic manifestation of a developmental gene anomaly. DESIGN:An observational case series. PA...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/S0161-6420(99)90539-0
更新日期:1999-12-01 00:00:00
abstract:OBJECTIVE:To assess the effectiveness of intravitreal aflibercept in patients with neovascular age-related macular degeneration (AMD) previously resistant to treatment with other anti-vascular endothelial growth factor agents. DESIGN:Prospective, open-label, noncontrolled, registered clinical trial. PARTICIPANTS:Fort...
journal_title:Ophthalmology
pub_type: 临床试验,杂志文章
doi:10.1016/j.ophtha.2013.08.035
更新日期:2014-01-01 00:00:00
abstract:PURPOSE:To investigate the distribution of the eye's higher-order aberrations in postoperative laser refractive surgery patients with visual complaints and highly irregular corneal shapes. DESIGN:Retrospective case-control study. PARTICIPANTS:Thirty-three symptomatic postoperative LASIK and/or photorefractive keratec...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2005.04.022
更新日期:2005-10-01 00:00:00
abstract:PURPOSE:To examine the safety and efficacy of anterior ciliary sclerotomy to restore accommodation in the presbyopic eye. DESIGN:Prospective nonrandomized comparative single-center clinical trial. PARTICIPANTS:Nine presbyopic subjects with no prior ocular surgery except corneal refractive procedures were enrolled. M...
journal_title:Ophthalmology
pub_type: 临床试验,杂志文章
doi:10.1016/s0161-6420(02)01252-6
更新日期:2002-11-01 00:00:00
abstract::The technique and results of conjunctival autograft transplantation for advanced and recurrent pterygium are presented for 57 eyes of 54 patients. The pterygia were primary in 16 eyes and recurrent in 41; among the latter group, 14 patients had diplopia resulting from cicatricial involvement of the medial rectus muscl...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(85)33831-9
更新日期:1985-11-01 00:00:00
abstract:PURPOSE:To investigate the frequency of sneezing among patients receiving intravenous sedation and periocular local anesthetic for oculoplastic procedures in a single center. To identify potential risk factors involved. DESIGN:Prospective, consecutive, interventional case series in a single tertiary-referral oculoplas...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2009.09.007
更新日期:2010-05-01 00:00:00
abstract:OBJECTIVE:To compare laser in situ keratomileusis (LASIK) with photorefractive keratectomy (PRK) in the correction of myopia from -2.00 to -5.50 diopters. DESIGN:Prospective, randomized, paired clinical trial. PARTICIPANTS:Fifty-two eyes of 26 myopic patients were enrolled in the study. INTERVENTION:Each patient rec...
journal_title:Ophthalmology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/S0161-6420(99)90084-2
更新日期:1999-02-01 00:00:00
abstract::Merkel cell carcinoma is an infrequent but highly aggressive cutaneous neoplasm. Previous reports of ocular involvement have included primary eyelid carcinomas, eyelid and orbital metastases, and a clinically diagnosed choroidal metastasis. The authors report the histopathologic documentation of a metastatic lesion to...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(91)32116-x
更新日期:1991-09-01 00:00:00
abstract:PURPOSE:To describe risk factors for scar formation and changes to fibrotic scar through 5 years in the Comparison of Age-related Macular Degeneration Treatments Trials (CATT). DESIGN:Multicenter, prospective cohort study. PARTICIPANTS:A total of 1061 subjects in CATT. METHODS:Color photographic and fluorescein angi...
journal_title:Ophthalmology
pub_type: 杂志文章,多中心研究
doi:10.1016/j.ophtha.2018.01.004
更新日期:2018-07-01 00:00:00
abstract:PURPOSE:To evaluate the effect of systemic factors on best-corrected visual acuity (BCVA) achieved with ranibizumab (Lucentis; Genentech, Inc, South San Francisco, CA) for treatment of diabetic macular edema (DME) in the RIDE and RISE phase 3 studies. DESIGN:Exploratory, post hoc analysis of 2 randomized, double-maske...
journal_title:Ophthalmology
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.ophtha.2016.03.038
更新日期:2016-07-01 00:00:00
abstract::An analysis of acute contact lens-related complications, with particular emphasis on severe microbial keratitis, was undertaken at the Department of Ophthalmology, Sahlgren's Hospital in Gothenburg. A total of 224 contact lens wearers presented with acute complications over a 2-year period (1981-1982). The lowest inci...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(87)33513-4
更新日期:1987-01-01 00:00:00
abstract::A 23-year-old woman presented with a 19-year history of unilateral, intermittently painful, slowly progressive proptosis. Clinical examination disclosed decreased orbital resiliency and choroidal folds in the posterior pole. Orbital echography revealed an acoustically empty cystic lesion superotemporally. Computerized...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(85)34103-9
更新日期:1985-12-01 00:00:00
abstract:PURPOSE:To investigate the independent impact of the incidence and progression of diabetic retinopathy (DR) on visual functioning (VF). DESIGN:Population-based cohort study. PARTICIPANTS:A total of 518 participants aged 40 to 80 years (baseline visit 2007-2009 and second visit 6 years later, 2013-2015), with diabetes...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2018.02.011
更新日期:2018-09-01 00:00:00
abstract:OBJECTIVE:To report endothelial cell densities (ECDs) and their correlation to anterior chamber depth (ACD) after implantation of the Artisan intraocular phakic lens. DESIGN:Prospective observational case series. PARTICIPANTS:Three hundred eighteen eyes of 173 myopic patients treated with the Artisan iris-fixated pha...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2007.05.036
更新日期:2008-04-01 00:00:00
abstract:PURPOSE:The purpose of this study was to determine the prevalence of open-angle glaucoma and ocular hypertension in an Australian community whose residents are 49 years of age or older. SUBJECTS:There were 3654 persons, representing 82.4% of permanent residents from an area west of Sydney, Australia, who were examined...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(96)30449-1
更新日期:1996-10-01 00:00:00