Insulin-like peptide(s) in the central nervous system of the snail Helisoma duryi.

abstract：:Extracellular signal-regulated kinase 1/2 (ERK1/2) plays diverse roles in the central nervous system. Activation of ERK1/2 has been observed in various types of neuronal excitation, including seizure activity in vivo and in vitro. However, studies examining ERK1/2 activity and its substrate phosphorylation in parallel...

journal_title：Brain research

authors： Yamagata Y,Nairn AC

更新日期：2015-11-02 00:00:00

abstract：:The phenomenon of ischemic tolerance has been closely associated with the expression of heat shock proteins but recently, stress tolerance not related to hsp72 has been reported. In the present study, we focused on ischemic tolerance induced by hypoxia and hyperthermia in neonatal rat brain and analyzed the expression...

journal_title：Brain research

authors： Wada T,Kondoh T,Tamaki N

更新日期：1999-11-20 00:00:00

abstract：:Quantal analysis of transmitter release is useful in examining presynaptic mechanisms involved in synaptic transmission. However, in central neurons, the presence of multiple synapses makes it difficult to use the traditional quantal analysis, developed for the neuromuscular transmission. We developed a method to mini...

journal_title：Brain research

authors： Singh G,Xu JY,Sastry BR

更新日期：2008-05-01 00:00:00

abstract：:The patch clamp technique has been used to study ion channel activity in the apical (ventricular) membrane of epithelial cells from the rat choroid plexus. Two different classes of Cl(-)-selective channel were identified. A low conductance (26 pS) channel which was the predominant feature in cell-attached and inside-o...

journal_title：Brain research

authors： Garner C,Brown PD

更新日期：1992-09-18 00:00:00

abstract：:It is well known that the nerve growth factor (NGF) may serve as a link between inflammation and hyperalgesia. Recent experiments showed that systemic injection of NGF dramatically stimulated the expression of brain-derived neurotrophic factor (BDNF) mRNA in the dorsal root ganglion (DRG). In the present study, we eva...

journal_title：Brain research

authors： Cho HJ,Kim SY,Park MJ,Kim DS,Kim JK,Chu MY

更新日期：1997-02-28 00:00:00

abstract：:Results of previous studies suggested that incertohypothalamic dopamine (IHDA) neurons located in the medial zona incerta (MZI) project to the central nucleus of the amygdala (cAMY), horizontal diagonal band of Broca (HDB), and paraventricular nucleus (PVN). The overall goal of the present study was to determine the r...

journal_title：Brain research

authors： Cheung S,Ballew JR,Moore KE,Lookingland KJ

更新日期：1998-10-19 00:00:00

abstract：:An interesting feature of the kindling phenomenon relates to the finding that kindling established in one region of the brain may reduce the number of stimulations required to establish the phenomenon in a second region. It has been proposed that this 'transfer' phenomenon reflects the extent to which seizures arising...

journal_title：Brain research

authors： Buchanan JA,Bilkey DK

更新日期：1997-10-10 00:00:00

abstract：:Monoclonal antibody N1 reacts by indirect immunofluorescence with the cell surface of tetanus toxin-positive neurons from early postnatal mouse cerebellum. In freshly trypsinized single cell suspensions from early postnatal mouse cerebellum, 5-10% of all viable cells express N1 antigen on their surface. After 3-24 h o...

journal_title：Brain research

authors： Schnitzer J,Kim SU,Schachner M

更新日期：1984-07-01 00:00:00

abstract：:The possibility that central adenosine A1 and A2a receptors mediate opiate dependence was examined in morphine-treated mice using radioligand binding methods. Mice treated with morphine for 72 h demonstrated significant increases in naloxone precipitated abstinence behaviors of jumping, wet-dog shakes, teeth chatterin...

journal_title：Brain research

authors： Kaplan GB,Leite-Morris KA,Sears MT

更新日期：1994-09-19 00:00:00

abstract：:In this study, we examined the immunohistochemical occurrence and distribution of glial cell line-derived neurotrophic factor (GDNF) in autoptic specimens of normal human hippocampus at different ages, from 22 weeks of gestation (w.g.) to adult life. Two different anti-GDNF polyclonal antibodies were used. Western blo...

journal_title：Brain research

authors： Pina Serra M,Quartu M,Ambu R,Follesa P,Del Fiacco M

更新日期：2002-02-22 00:00:00

abstract：:Insulin-like growth factor (IGF) II receptors were studied in human adult brain by using autoradiography with [125I]IGF-II. Receptors were found to be widely distributed throughout all neuronal regions. The highest densities were found in plexus choroideus, granular layer of the cerebellar cortex, gyrus dendatus and p...

journal_title：Brain research

authors： Wilczak N,De Bleser P,Luiten P,Geerts A,Teelken A,De Keyser J

更新日期：2000-04-28 00:00:00

abstract：:Somatostatin-like immunoreactivity (Som-LI) and glycine high-affinity uptake have been characterized in the Rana pipiens retina. These labels are found in both the outer and inner plexiform layers (OPL and IPL), suggesting that interplexiform cells (IPCs) contain both Som and glycine in this retina. In double-label ex...

journal_title：Brain research

authors： Smiley JF,Basinger SF

更新日期：1989-08-21 00:00:00

abstract：:The effect of chronic administration of morphine to rats on the N-methyl-D-aspartate (NMDA) receptors labeled with [3H]MK-801, a non-competitive antagonist, was determined in brain regions and spinal cord. Male Sprague-Dawley rats were rendered tolerant to and physically dependent on morphine by subcutaneous implantat...

journal_title：Brain research

authors： Gudehithlu KP,Reddy PL,Bhargava HN

更新日期：1994-03-14 00:00:00

abstract：:The role of central delta-opioid receptors in the mediation of opioid reinforcement and endogenous reward processes was examined using a non-biased place-preference conditioning procedure. Intracerebroventricular (i.c.v.) administration of the selective delta-receptor agonist, [D-Pen2, D-Pen5]-enkephalin (DPDPE, 10.0-...

journal_title：Brain research

authors： Shippenberg TS,Bals-Kubik R,Herz A

更新日期：1987-12-15 00:00:00

abstract：:Genetic abnormalities in amyloid precursor protein (APP) are associated with Down's syndrome and familial Alzheimer's disease where hallmark plaques contain A beta peptides derived from APP. Both APP and its derivatives are implicated in neurodegenerative processes and may play important physiological and pathophysiol...

journal_title：Brain research

authors： Senechal Y,Prut L,Kelly PH,Staufenbiel M,Natt F,Hoyer D,Wiessner C,Dev KK

更新日期：2008-12-03 00:00:00

abstract：:Immunocytochemical and morphometric analyses were combined to demonstrate the presence of neuron subpopulations in the rat vestibular ganglion. Monoclonal antibodies reacting with neurofilament proteins (NF), calbindin-D 28K (CaBP) and calretinin (CaR) were used. Three subpopulations were identified: (1) CaBP- and CaR...

journal_title：Brain research

authors： Demêmes D,Raymond J,Atger P,Grill C,Winsky L,Dechesne CJ

更新日期：1992-06-05 00:00:00

abstract：:Perinatal asphyxia to the developing brain remains a major cause of morbidity. Hypothermia is currently the only established neuroprotective treatment available for term born infants with hypoxic-ischemic encephalopathy, saving one in seven to eight infants from developing severe neurological deficits. Therefore, addi...

journal_title：Brain research

authors： Strasser K,Lueckemann L,Kluever V,Thavaneetharajah S,Hoeber D,Bendix I,Fandrey J,Bertsche A,Felderhoff-Mueser U

更新日期：2016-09-01 00:00:00

abstract：:The effect of repetitive stimulation of the locus coeruleus (LC) on the discharge rate of spontaneously active neurons of the visual, rostral and cingulate cortex was investigated in untreated and catecholamine-depleted rats under chloral hydrate anesthesia. In untreated animals, the inhibitory transsynaptic effects p...

journal_title：Brain research

authors： Olpe HR,Glatt A,Laszlo J,Schellenberg A

更新日期：1980-03-17 00:00:00

abstract：:Aluminum (Al), an important neurotoxin, contributes to a variety of cognitive dysfunction and mental diseases. Previous studies have demonstrated that Al impairs hippocampal long-term potentiation (LTP) in vitro and in vivo. In the present study, both LTP and LTD (long-term depression) were recorded in the same animal...

journal_title：Brain research

authors： Wang M,Chen JT,Ruan DY,Xu YZ

更新日期：2001-04-27 00:00:00

abstract：:Infusion of 15 micrograms/microliters (approximately 120 micrograms/kg/h) of indomethacin within the ventral septal area of the rat brain significantly reduced a centrally induced prostaglandin E1 (PGE1) hyperthermia when compared with infusions of artificial cerebrospinal fluid. A bolus injection of a V1 receptor ant...

journal_title：Brain research

authors： Fyda DM,Cooper KE,Veale WL

更新日期：1989-08-14 00:00:00

abstract：:Neurotrophic factors (NTFs), beside regulating neuronal survival in the central and peripheral nervous system, are also involved in the modulation of neuronal function in the adult animal. Both brain-derived neurotrophic factor (BDNF) and glial cell-derived neurotrophic factor (GDNF) levels are altered in pathological...

journal_title：Brain research

authors： Ciobanu C,Reid G,Babes A

更新日期：2009-08-11 00:00:00

abstract：:Neurotrophins are potent regulators of the survival of different neuronal populations in the CNS. Little is known of the immunodistribution of neurotrophin-3 (NT-3) and tyrosine kinase C (TrkC) receptor in the frog visual system, which can successfully regenerate and recover vision after injury. In this study we show ...

journal_title：Brain research

authors： Duprey-Díaz MV,Blagburn JM,Blanco RE

更新日期：2003-08-22 00:00:00

abstract：:Effect of a mu-opioid agonist (D-Ala2,N-MePhe4,Gly5-ol-enkephalin, DAGO), on glycine (Gly)-induced chloride current (IGly) was investigated in the periaqueductal gray (PAG) neurons acutely dissociated 1-2-week-old Wistar rats by the use of nystatin-perforated patch recording configuration under voltage-clamp condition...

journal_title：Brain research

authors： Min BI,Kim CJ,Rhee JS,Akaike N

更新日期：1996-09-23 00:00:00

abstract：:In a rat model of peripheral inflammation and hyperalgesia, dynorphin A(1-8)-like immunoreactive (DYN-LIr) spinal neurons were examined for contacts from calcitonin gene-related peptide-like immunoreactive (CGRP-LIr) varicosities using a double-label PAP method. Ipsilateral to the inflammation, CGRP-LIr varicosities c...

journal_title：Brain research

authors： Takahashi O,Traub RJ,Ruda MA

更新日期：1988-12-13 00:00:00

abstract：:Previous studies in piglets show that opioid-induced pial artery dilation was impaired following fluid percussion brain injury (FPI). This study was designed to determine the role of the newly described opioid nociceptin orphanin FQ (NOC/oFQ) in such impaired dilation to other opioids after FPI. CSF NOC/oFQ concentrat...

journal_title：Brain research

authors： Armstead WM

更新日期：2000-06-30 00:00:00

abstract：:The relationship between carotid body chemoreceptor activity and flow was studied in preparations superfused in vitro. The carotid bodies were excised from pentobarbitone-anesthetized cats and superfused with modified Tyrode's solution, buffered with HEPES-NaOH to pH 7.41. The bath temperature was kept constant at 37....

journal_title：Brain research

authors： Alcayaga J,Iturriaga R,Zapata P

更新日期：1988-07-05 00:00:00

abstract：:An extensive mapping of the caudate-putamen in rat for intracranial self-stimulation (ICS) site was undertaken to provide addtional support for the role of dopamine in brain-stimulation reward. Eight-seven per cent of the placements in the neostriatum supported ICS, with self-stimulation rates greater than 250/15 min ...

journal_title：Brain research

authors： Phillips AG,Carter DA,Fibiger HC

更新日期：1976-03-12 00:00:00

abstract：:The influence of emotion on cognition plays an important role in people's everyday life as well as in psychiatric and neurological disorders. The present study used fMRI to examine the neural correlates of cognitive-emotional interactions and its inter-individual differences. Twenty-one healthy males performed a 0-bac...

journal_title：Brain research

authors： Habel U,Koch K,Pauly K,Kellermann T,Reske M,Backes V,Seiferth NY,Stöcker T,Kircher T,Amunts K,Jon Shah N,Schneider F

更新日期：2007-06-04 00:00:00

abstract：:Several lines of evidence indicate that psychostimulant withdrawal can induce negative emotional symptoms, such as anhedonia and dysphoria, which may be due in part, to dysfunction of the serotonin (5-HT) system, including alterations in 5-HT receptors. For example, changes in 5-HT(2A) receptor function in prefrontal ...

journal_title：Brain research

authors： Horner KA,Gilbert YE,Noble ES

更新日期：2011-05-16 00:00:00

abstract：:S-allyl cysteine (SAC), a sulfur containing amino acid derived from garlic, has been reported to have antioxidant, anti-cancer, antihepatotoxic and neurotrophic activity. This study was designed to examine the pre-treatment effects of SAC on cognitive deficits and oxidative damage in the hippocampus of intracerebroven...

journal_title：Brain research

authors： Javed H,Khan MM,Khan A,Vaibhav K,Ahmad A,Khuwaja G,Ahmed ME,Raza SS,Ashafaq M,Tabassum R,Siddiqui MS,El-Agnaf OM,Safhi MM,Islam F

更新日期：2011-05-10 00:00:00