Abstract:
OBJECTIVE:End-stage renal disease (ESRD) requiring renal replacement therapy (RRT) is a late complication of type 2 diabetes. The correlation between pre-ESRD medical care and outcome has been rarely studied in France. METHODS:Community-based study of case-incIdent ESRD patients. Medical care practices were described retrospectively when starting RRT. Medical status, mortality, morbIdity, and quality-of-life were recorded prospectively. RESULTS:One hundred and fourty-eight ESRD patients with type 2 diabetes were included. Factors independently correlated with mortality within 3 Months of RRT onset were presence of physical impairment of ambulation at onset of RRT [odd ratio (OR): 5, (95%CI: 1.9-13.3)], and starting RRT in life-threatening circumstances [OR: 3.6, (95%CI: 1.2-10.7)]. Factors independently correlated with "poor outcome" 1 Year after the onset of RRT were BMI less than 20 kg/m2 [OR: 13.4, (95%CI: 1.5-120.2)] and presence of 2 [OR: 2.7, (95%CI: 0.9-8.4)], or 3 or more comorbId conditions [OR: 4, (95% CI: 1.4-11)]. Three Months after the first RRT session, survival was 16.4% better for patients who had had regular nephrological care versus none, and 9.1% better for those who had had late nephrological care versus none. Type 2 diabetes patients starting RRT in an emergency setting had had significant less regular nephrological care. Length of their first hospital stay was significantly longer. They were more likely to have lower resIdual renal function, gastrointestinal symptoms, lower serum albumin, lower hematocrit, lower serum calcium, and higher serum phosphorus. CONCLUSIONS:During the course of chronic renal failure in type 2 diabetes patients, early implementation of nephrological well-established guIdelines is associated with better outcome after starting RRT.
journal_name
Diabetes Metabjournal_title
Diabetes & metabolismauthors
Frimat L,Loos-Ayav C,Panescu V,Cordebar N,Briançon S,Kessler Mdoi
10.1016/s1262-3636(07)70091-5subject
Has Abstractpub_date
2004-02-01 00:00:00pages
67-74issue
1eissn
1262-3636issn
1878-1780pii
s1262-3636(07)70091-5journal_volume
30pub_type
杂志文章abstract::The peroxisome proliferator-activated receptor protein gamma (PPARγ), a nuclear receptor involved in adipocyte differentiation, energy homoeostasis and fat storage, can lead, in rare cases of coding mutations, to familial partial lipodystrophy type 3 (FPLD3) with severe insulin resistance. PPARγ is also highly express...
journal_title:Diabetes & metabolism
pub_type: 杂志文章
doi:10.1016/j.diabet.2012.02.012
更新日期:2012-10-01 00:00:00
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journal_title:Diabetes & metabolism
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doi:10.1016/j.diabet.2017.06.008
更新日期:2018-02-01 00:00:00
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journal_title:Diabetes & metabolism
pub_type: 杂志文章
doi:10.1016/j.diabet.2010.12.008
更新日期:2011-11-01 00:00:00
abstract:AIM:Experimental evidence suggests that osteocalcin is a key messenger that affects both adipocytes and insulin-producing β cells. Epidemiological cross-sectional studies have shown a negative association between plasma levels of osteocalcin and glucose. For this reason, the hypothesis that lower baseline osteocalcin p...
journal_title:Diabetes & metabolism
pub_type: 杂志文章
doi:10.1016/j.diabet.2014.01.001
更新日期:2014-06-01 00:00:00
abstract::The Diabetes and Cardiovascular Disease study group of the Société francophone du diabète (SFD, French Society of Diabetes) in collaboration with the Société française de cardiologie (SFC, French Society of Cardiology) have devised a consensus statement on the care of the hyperglycaemic/diabetic patient during and in ...
journal_title:Diabetes & metabolism
pub_type: 杂志文章,实务指引
doi:10.1016/j.diabet.2011.11.003
更新日期:2012-04-01 00:00:00
abstract:OBJECTIVE:To study the efficacy of the nutritional education software, Nutri-Expert, in the management of obese adult patients. MATERIAL AND METHODS:Two groups of obese patients were followed up over one year in a randomized study: the first group received close traditional management (seven nutritional visits over th...
journal_title:Diabetes & metabolism
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:
更新日期:2001-04-01 00:00:00
abstract:INTRODUCTION:While guidelines for detection of silent myocardial and lower limb ischemia are established, data on screening asymptomatic carotid lesions remain scarce. However, such screening would be costly. Since the prevalence of diabetes increases constantly, it is necessary to keep screening costs low by setting u...
journal_title:Diabetes & metabolism
pub_type: 杂志文章
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journal_title:Diabetes & metabolism
pub_type: 杂志文章
doi:10.1016/j.diabet.2008.08.005
更新日期:2009-04-01 00:00:00
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journal_title:Diabetes & metabolism
pub_type: 杂志文章
doi:10.1016/j.diabet.2007.10.001
更新日期:2007-12-01 00:00:00
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journal_title:Diabetes & metabolism
pub_type: 杂志文章
doi:
更新日期:1998-11-01 00:00:00
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journal_title:Diabetes & metabolism
pub_type: 杂志文章
doi:10.1016/j.diabet.2019.01.012
更新日期:2019-10-01 00:00:00
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journal_title:Diabetes & metabolism
pub_type: 杂志文章,评审
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更新日期:2013-02-01 00:00:00
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journal_title:Diabetes & metabolism
pub_type: 杂志文章
doi:10.1016/j.diabet.2018.09.007
更新日期:2019-09-01 00:00:00
abstract::Strict glycaemic control is a major concern in many people with diabetes, hypoglycaemia being the most limiting factor in the daily management of patients with diabetes. Acute consequences of hypoglycaemic attacks are not precisely evaluated. Acute cardiovascular (CV) complications as myocardial ischaemia or stroke se...
journal_title:Diabetes & metabolism
pub_type: 杂志文章,评审
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更新日期:2010-10-01 00:00:00
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journal_title:Diabetes & metabolism
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.diabet.2011.06.001
更新日期:2011-12-01 00:00:00
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journal_title:Diabetes & metabolism
pub_type: 杂志文章,评审
doi:10.1016/j.diabet.2015.08.005
更新日期:2015-12-01 00:00:00
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journal_title:Diabetes & metabolism
pub_type: 杂志文章
doi:10.1016/j.diabet.2012.10.009
更新日期:2013-05-01 00:00:00
abstract::Type 2 diabetes is characterised by insulin resistance in association with clustering of atherothrombotic risk factors (dysglycaemia, hyperinsulinaemia, hypertension, raised triglyceride, low HDL cholesterol and increased levels of plasminogen activator inhibitor-1 (PAI-1) and clotting factor VII). There is a 3-5 fold...
journal_title:Diabetes & metabolism
pub_type: 杂志文章,评审
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journal_title:Diabetes & metabolism
pub_type: 杂志文章
doi:10.1016/j.diabet.2009.04.010
更新日期:2009-12-01 00:00:00
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journal_title:Diabetes & metabolism
pub_type: 杂志文章
doi:
更新日期:2000-04-01 00:00:00
abstract::Obesity and visceral or upper body fat distribution, have a major impact on insulin sensitivity. There is strong evidence to suggest that free fatty acids (FFA) contribute to the pathogenesis of insulin resistance and the metabolic syndrome. Increased FFA release from adipose tissue or failure of FFA using tissues to ...
journal_title:Diabetes & metabolism
pub_type: 杂志文章,评审
doi:
更新日期:2001-04-01 00:00:00
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journal_title:Diabetes & metabolism
pub_type: 临床试验,杂志文章
doi:
更新日期:1998-12-01 00:00:00
abstract::Prevalence of diabetes is increasing worldwide in epidemic proportions. Its appropriate clinical management requires a careful etiological diagnosis. Laminopathies recently emerged as clinically heterogeneous genetic disorders due to mutations in lamins or lamin-associated proteins, which are components of the nuclear...
journal_title:Diabetes & metabolism
pub_type: 杂志文章,评审
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更新日期:2005-12-01 00:00:00
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journal_title:Diabetes & metabolism
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doi:10.1016/j.diabet.2019.07.003
更新日期:2020-06-01 00:00:00
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journal_title:Diabetes & metabolism
pub_type: 杂志文章
doi:10.1016/s1262-3636(07)70217-3
更新日期:2005-11-01 00:00:00
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journal_title:Diabetes & metabolism
pub_type: 杂志文章,评审
doi:10.1016/j.diabet.2007.08.002
更新日期:2008-02-01 00:00:00
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journal_title:Diabetes & metabolism
pub_type: 历史文章,杂志文章,评审
doi:
更新日期:2003-04-01 00:00:00
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更新日期:2021-01-23 00:00:00
abstract::Type 1 diabetes (T1D) is due to the loss of both beta-cell insulin secretion and glucose sensing, leading to glucose variability and a lack of predictability, a daily issue for patients. Guidelines for the treatment of T1D have become stricter as results from the Diabetes Control and Complications Trial (DCCT) demonst...
journal_title:Diabetes & metabolism
pub_type: 杂志文章,评审
doi:10.1016/j.diabet.2013.10.003
更新日期:2014-04-01 00:00:00
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journal_title:Diabetes & metabolism
pub_type: 杂志文章,多中心研究,随机对照试验
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更新日期:2012-10-01 00:00:00