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Hypothermia with acute renal failure in a patient suffering from diabetic nephropathy and malnutrition.

Abstract：

:We report a rare case of hypothermia with acute renal failure in a patient suffering from diabetic nephropathy. A 71-year-old male who had been receiving insulin therapy for the treatment of diabetes mellitus complicated with advanced diabetic nephropathy since 1998 was malnourished with an extremely decreased muscle mass. Without any prolonged exposure to excessively low external temperatures or hypothyroidism, pituitary insufficiency, adrenal insufficiency, sepsis, hypoglycemia, and diabetic ketoacidosis, acute hypothermia appeared together with an aggravation of diabetic nephropathy. His skin temperature fell to below measurable levels and his rectal temperature fell to 30.0 degrees C. His consciousness was drowsy and the hypothermia was not accompanied by shivering. Skeletal muscle is known to play an important role as a center of heat production and shivering thermogenesis in skeletal muscle mainly operates on acute cold stress. Therefore, in this case, hypothermia may have occurred because the shivering thermogenesis could not fully act on the acute cold stress due to the dramatically reduced muscle mass. We should always keep in mind that older, malnourished diabetic patients can easily suffer from impairments of the thermoregulatory system.

journal_name

Diabetes Metab

journal_title

Diabetes & metabolism

authors

Yokoyama M,Noto Y,Kida H

subject

Has Abstract

pub_date

2000-04-01 00:00:00

pages

145-7

issue

2

eissn

1262-3636

issn

1878-1780

pii

MDOI-DM-05-2000-26-2-1262-3636-101019-ART84

journal_volume

26

pub_type

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