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Evaluation and risk stratification of acute coronary syndromes using a low cut-off level of cardiac troponin T, combined with CK-MB mass determination.

Abstract：

OBJECTIVES:To study the usefulness of combined cardiac Troponin T (cTnT) and CK-MB mass determinations in risk stratification of acute coronary syndromes. DESIGN AND METHODS:Blood samples for cTnT and CK-MB mass were collected at arrival and 4, 8, and 12-24 later in 301 consecutive patients with recent acute chest pain (ACP). Data were also collected for cardiac events. RESULTS:Combined cardiac mortality/nonfatal myocardial infarction over a period of 15 months was lowest in patients with <0.04 microg/l cTnT and -<5.0 microg/l CK-MB mass intermediate in those with elevated cTnT but normal CK-MB mass and highest when both markers were elevated, in absence of early reperfusion. CONCLUSION:The use of a low cut-off point of cTnT, combined wit CK-MB mass determination, offers a good strategy for risk stratification of ACP patients.

journal_name

Clin Biochem

journal_title

Clinical biochemistry

authors

Solymoss BC,Bourassa MG,Fortier A,Théroux P

doi

10.1016/j.clinbiochem.2003.12.003

subject

Has Abstract

pub_date

2004-04-01 00:00:00

pages

286-92

issue

4

eissn

0009-9120

issn

1873-2933

pii

S0009912003002558

journal_volume

37

pub_type

杂志文章

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