Confocal analysis of fluorescent bead uptake by mouse Peyer's patch follicle-associated M cells.

abstract：NEW FINDINGS:What is the topic of this review? This article draws evidence from the current literature to support the hypothesis that non-coding RNA-mediated gene regulation takes place in the mitochondria. An emphasis is put on skeletal muscle. What advances does it highlight? This review highlights the potential role...

journal_title：Experimental physiology

authors： Silver J,Wadley G,Lamon S

更新日期：2018-08-01 00:00:00

abstract：:Non-invasive autonomic evaluation has used fast Fourier transform (FFT) to assign a range of low (LF) and high frequencies (HF) as markers of sympathetic and parasympathetic influences, respectively. However, FFT cannot be applied to brief transient phenomena, such as those observed on performing autonomic tests where...

journal_title：Experimental physiology

authors： Ducla-Soares JL,Santos-Bento M,Laranjo S,Andrade A,Ducla-Soares E,Boto JP,Silva-Carvalho L,Rocha I

更新日期：2007-07-01 00:00:00

abstract：:The present study was designed to analyse the effects of aerobic exercise on the metabolic effects of alloxan. Male Wistar newborn rats (2 days old) received alloxan (200 mg (kg body weight)(-1)) intraperitoneally (A rats). Vehicle-injected rats were used as controls (C rats). At 28 days old, some of the A rats were s...

journal_title：Experimental physiology

authors： de Oliveira CA,Luciano E,de Mello MA

更新日期：2005-01-01 00:00:00

abstract：:What is the central question of this study? Failure to terminate apnoea and arouse is likely to contribute to sudden infant death syndrome (SIDS). Serotonin is deficient in the brainstems of babies who died of SIDS. Therefore, we tested the hypothesis that serotonin in the nucleus of the solitary tract (NTS) would sho...

journal_title：Experimental physiology

authors： Donnelly WT,Bartlett D Jr,Leiter JC

更新日期：2016-07-01 00:00:00

abstract：NEW FINDINGS:What is the topic of this review? This brief review discusses potential sex differences in arterial function across the age span, with special emphasis on the effects of oestrogen and testosterone on the vascular endothelium. What advances does it highlight? We discuss the relationship between the impacts ...

journal_title：Experimental physiology

authors： Green DJ,Hopkins ND,Jones H,Thijssen DH,Eijsvogels TM,Yeap BB

更新日期：2016-02-01 00:00:00

abstract：:Sodium appetite, the behavioural drive to ingest salt, is stimulated by prolonged physiological sodium deficiency in many animal species. The same neural mechanisms that are responsible for sodium appetite in laboratory animals may influence human behaviour as well, with particular relevance to the dietary salt intake...

journal_title：Experimental physiology

authors： Geerling JC,Loewy AD

更新日期：2008-02-01 00:00:00

abstract：:Neuropeptides and regulatory peptide hormones control many developmental, physiological and behavioural processes in animals, including humans. The nonapeptides oxytocin and arginine vasopressin are produced and released by the pituitary gland and have actions on many organs and tissues. Receptive cells possess partic...

journal_title：Experimental physiology

authors： Gruber CW

更新日期：2014-01-01 00:00:00

abstract：NEW FINDINGS:What is the central question of this study? Does recreational cold exposure result in cold sensitivity and is this associated with endothelial dysfunction and impaired sensory thermal thresholds? What is the main finding and its importance? Previous cold exposure was correlated with cold sensitivity of the...

journal_title：Experimental physiology

authors： Eglin CM,Costello JT,Tipton MJ,Massey H

更新日期：2021-01-01 00:00:00

abstract：:Flow of submandibular saliva and the constituents secreted during chorda-lingual nerve stimulation at 40 Hz (3 x 10 min) were studied after alpha- and beta-adrenergic blockade, and in the absence (control) or presence of cholinergic blockade in anaesthetized rats. Peroxidase and true tissue kallikrein (rK1) were asses...

journal_title：Experimental physiology

authors： Garrett JR,Anderson LC,Zhang XS,Proctor GB

更新日期：1996-05-01 00:00:00

abstract：:Obstructive sleep apnoea (OSA) leads to chronic intermittent hypoxia (CIH) during sleep. Obstructive sleep apnoea has been associated with liver injury. Acetaminophen (APAP; known as paracetamol outside the USA) is one of the most commonly used drugs which has known hepatotoxicity. The goal of the present study was to...

journal_title：Experimental physiology

authors： Savransky V,Reinke C,Jun J,Bevans-Fonti S,Nanayakkara A,Li J,Myers AC,Torbenson MS,Polotsky VY

更新日期：2009-02-01 00:00:00

abstract：:Aortic bodies are arterial chemoreceptors presumed to monitor blood O2 content by unknown mechanisms, in contrast to their well-studied carotid body counterparts, which monitor PO2 and /pH. We recently showed that rat aortic body chemoreceptors (type I cells), located at the left vagus-recurrent laryngeal nerve bifurc...

journal_title：Experimental physiology

authors： Piskuric NA,Zhang M,Vollmer C,Nurse CA

更新日期：2014-01-01 00:00:00

abstract：:Ionic mechanisms and signal transduction underlying noradrenaline (NA)-induced depolarization in single smooth muscle cells of guinea-pig vas deferens were studied. NA caused depolarization followed by action potentials through activation of 1-adrenoceptors. In the presence of nifedipine, no action potential was gener...

journal_title：Experimental physiology

authors： Kamimura N,Suga S,Nakano K,Kanno T,Takeo T,Wakui M

更新日期：2000-01-01 00:00:00

abstract：:The effects of hypotonic solutions on intracellular Ca2+ were determined on primary cultures of human detrusor smooth muscle cells. In the presence of external Ca2+, changing from a solution containing 290 mosmol l-1 to one containing 240 mosmol l-1 (80% normal tonicity) activated a rise in intracellular Ca2+. If the ...

journal_title：Experimental physiology

authors： Chambers P,Neal DE,Gillespie JI

更新日期：1997-07-01 00:00:00

abstract：:Methyl CpG binding protein-2 (MECP2) is a chromatin-remodelling factor with a dual role in gene expression. Evidence from patients carrying MECP2 mutations and from transgenic mouse models demonstrates that this protein is involved in the control of body weight. However, the mechanism for this has not been fully eluci...

journal_title：Experimental physiology

authors： Torres-Andrade R,Moldenhauer R,Gutierrez-Bertín N,Soto-Covasich J,Mancilla-Medina C,Ehrenfeld C,Kerr B

更新日期：2014-09-01 00:00:00

abstract：:We present a curve-fitting approach that permits quantitative comparisons of fatigue profiles obtained with different stimulation protocols in isolated slow-twitch soleus and fast-twitch extensor digitorum longus (EDL) muscles of mice. Profiles from our usual stimulation protocol (125 Hz for 500 ms, evoked once every ...

journal_title：Experimental physiology

authors： Cairns SP,Robinson DM,Loiselle DS

更新日期：2008-07-01 00:00:00

abstract：NEW FINDINGS:What is the central question of this study? Clinical studies suggest that obesity 'protects' against osteoporosis. However, these studies used only bone densitometry and assessed only one bone site, which is insufficient to enable conclusions to be drawn about the response of the whole skeleton. Furthermor...

journal_title：Experimental physiology

authors： Lacerda DR,Serakides R,de Melo Ocarino N,Ferreira AV,Moraes MM,Boeloni JN,Silva JF,de Oliveira MC,de Barcellos LA,Rodrigues LO,Soares DD

更新日期：2015-01-01 00:00:00

abstract：NEW FINDINGS:What is the central question of this study? Compared with Caucasians, African individuals are more susceptible to non-freezing cold injury and experience greater cutaneous vasoconstriction and cooler finger skin temperatures upon hand cooling. We investigated whether the enzyme cyclooxygenase is, in part, ...

journal_title：Experimental physiology

authors： Maley MJ,House JR,Tipton MJ,Eglin CM

更新日期：2017-07-01 00:00:00

abstract：:Six untrained, male subjects (23 +/- 1 years old, 84 +/- 5 kg, (O(2)peak)= 3.7 +/- 0.8 l min(-1)) exercised for 60 min at 75 +/- 1%(O(2)peak) on 7 consecutive days. Muscle samples were obtained before the start of cycle exercise training and 24 h after the first and seventh exercise sessions and analysed for citrate s...

journal_title：Experimental physiology

authors： Kraniou GN,Cameron-Smith D,Hargreaves M

更新日期：2004-09-01 00:00:00

abstract：:The hypotensive and vasorelaxing peptides adrenomedullin (AM) and its gene-related peptide, proadrenomedullin N-terminal 20 peptide (PAMP), were found to be distributed on the surface of the colonic mucosa. AM and PAMP showed dose-dependent antimicrobial activity against E. coli. The results suggest that the novel vas...

journal_title：Experimental physiology

authors： Marutsuka K,Nawa Y,Asada Y,Hara S,Kitamura K,Eto T,Sumiyoshi A

更新日期：2001-09-01 00:00:00

abstract：:A great variety of viruses have been engineered to serve as expression vectors. Among them, the alphaviruses Semliki Forest virus and Sindbis virus represent promising tools for heterologous gene expression in a wide variety of host cells. Several applications have already been described in neurobiological studies, in...

journal_title：Experimental physiology

authors： Rhême C,Ehrengruber MU,Grandgirard D

更新日期：2005-01-01 00:00:00

abstract：:The intrinsic proton buffering power (beta 1) of individual rat hippocampal and neocortical neurones maintained in culture has been investigated using the fluorescent dye 2', 7'-bis(carboxymethyl)-5, 6-(carboxyfluorescein) (BCECF). The steady-state intracellular pH (pH1) was estimated to be 7.03 +/- 0.04 (n = 22) in H...

journal_title：Experimental physiology

authors： Amos BJ,Richards CD

更新日期：1996-03-01 00:00:00

abstract：:In anaesthetized cats, it was possible to enhance the dynamic sensitivity to stretch of jaw muscle spindle primary afferents by electrical stimulation in the midbrain. This effect was taken to be due to excitation of dynamic fusimotor neurones and was used to identify fusimotor fibres as static or dynamic in recording...

journal_title：Experimental physiology

authors： Donga R,Taylor A,Jüch PJ

更新日期：1993-01-01 00:00:00

abstract：:Neural mediation of the human cardiac response to isocapnic (IC) steady-state hypoxaemia was investigated using coarse-graining spectral analysis of heart rate variability (HRV). Six young adults were exposed in random order to a hypoxia or control protocol, in supine and sitting postures, while end-tidal PCO2 (PET,CO...

journal_title：Experimental physiology

authors： Lucy SD,Hughson RL,Kowalchuk JM,Paterson DH,Cunningham DA

更新日期：2000-03-01 00:00:00

abstract：:Phosphoethanolamine and taurine have been identified in uterine extracts from rat and, for the first time, human tissue. The concentration of phosphoethanolamine [PEtn] determined by HPLC and 31P NMR spectroscopy, increased markedly (40%) within the first 6-12 h following parturition in rats, suggesting a role in invo...

journal_title：Experimental physiology

authors： Phoenix J,Wray S

更新日期：1994-07-01 00:00:00

abstract：:In vivo microperfusion techniques were used to investigate the role of Na+-H+ exchange in the efferent ducts of the rat. Individual efferent ducts were perfused with a Krebs-Ringer bicarbonate solution (KRB) containing 0, 1, 3, 5 or 7.5 mM amiloride. Concentrations of 1-5 mM amiloride inhibited fluid reabsorption from...

journal_title：Experimental physiology

authors： Hansen LA,Clulow J,Jones RC

更新日期：1999-05-01 00:00:00

abstract：:The aim of this study was to evaluate whether long-term administration of L-arginine, a physiological substrate for the production of nitric oxide, improved blood pressure, heart rate, cardiac hypertrophy and particularly structural changes in the coronary and carotid artery of spontaneously hypertensive rats (SHR). T...

journal_title：Experimental physiology

authors： Kristek F

更新日期：1998-09-01 00:00:00

abstract：:In Helix aspersa, activation of the cerebral giant serotonin neurones (GSNs) evokes a biphasic, excitatory synaptic response in the M neurones of the buccal ganglia. Local application of serotonin to the current-clamped M neurones also evokes fast and slow depolarizing responses. The slow response is thought to be dep...

journal_title：Experimental physiology

authors： Hill-Venning C,Cottrell GA

更新日期：1992-11-01 00:00:00

abstract：:In order to investigate the effect of chronic sodium depletion on renal proximal tubular reabsorption, studies were performed in conscious, unrestrained Brattleboro rats. Since these animals lack circulating vasopressin, fractional water reabsorption in the distal nephron can be assumed to be constant and changes in u...

journal_title：Experimental physiology

authors： Shirley DG,Skinner J

更新日期：1994-03-01 00:00:00

abstract：:The dorsal horn of the spinal cord plays an important role in transmitting information from nociceptive primary afferent neurones to the brain; however, our knowledge of its neuronal and synaptic organisation is still limited. Nociceptive afferents terminate mainly in laminae I and II and some of these contain substan...

journal_title：Experimental physiology

authors： Todd AJ

更新日期：2002-03-01 00:00:00

abstract：:Experiments were performed to investigate, in the normal and acutely inflamed rabbit knee joint, the role of prostaglandins in the regulation of joint blood flow, measured by laser Doppler flowmetry, as well as their modulation of sympathetic vasoconstriction. Close intra-arterial injection of prostaglandin E2 (PGE2) ...

journal_title：Experimental physiology

authors： Najafipour H,Ferrell WR

更新日期：1994-01-01 00:00:00