当前位置： SCI文献检索 > EUROPEAN JOURNAL OF CLINICAL NUTRITION期刊下所有文献 > Association between antioxidant nutritional indicators and the incidence of dementia: results from the PAQUID prospective cohort study.

Association between antioxidant nutritional indicators and the incidence of dementia: results from the PAQUID prospective cohort study.

Abstract：

OBJECTIVE:To analyse the relation between antioxidant vitamins A, E, and malondialdehyde (MDA) lipoperoxidation product plasma concentrations with incident dementia. DESIGN:: A nested case-control within the PAQUID (Personnes Agées QUID) cohort. SETTING:The PAQUID population-based prospective cohort in southwestern France. SUBJECTS:Among 626 subjects with blood collection at baseline, 46 developed a dementia during the follow-up and were considered to be cases. Each case was matched (on age and sex) to three controls. RESULTS:Plasma vitamin E concentrations were lower among cases (mean value at 22.62 micromol/l (s.d.: 7.38) vs 24.99 (s.d.: 6.73 among controls). The same trend was observed for vitamin A concentrations, but the difference was not significant. On the contrary, MDA concentrations tended to be higher (mean value 1.35 micromol/l (s.d.: 0.53) vs 1.23 (s.d.: 0.44)) among cases. In logistic regression models, plasma values were split into tertiles. Adjusted for confounders, the risk of dementia was significantly increased in the lowest vitamin E tertile (< or =21.0 micromol/l) (OR=3.12, P=0.033) compared to the highest one (> or =25.5 micromol/l). The risk of Alzheimer's disease was also increased, with borderline significance (OR=3.06, P=0.053). Risks associated with vitamin A were nonsignificant. Similarly, there was a trend to an increased risk of dementia in the highest tertile of MDA (OR=1.67, P=0.31). CONCLUSIONS:These results suggest that subjects with low plasma vitamin E concentrations are at a higher risk of developing a dementia in subsequent years.

journal_name

Eur J Clin Nutr

journal_title

European journal of clinical nutrition

authors

Helmer C,Peuchant E,Letenneur L,Bourdel-Marchasson I,Larrieu S,Dartigues JF,Dubourg L,Thomas MJ,Barberger-Gateau P

doi

10.1038/sj.ejcn.1601724

subject

Has Abstract

pub_date

2003-12-01 00:00:00

pages

1555-61

issue

12

eissn

0954-3007

issn

1476-5640

pii

1601724

journal_volume

57

pub_type

杂志文章

相关文献

EUROPEAN JOURNAL OF CLINICAL NUTRITION文献大全
  • Excretion of amino acid residues from diets based on wheat flour or oat bran in human subjects with ileostomies.

    abstract：OBJECTIVES:The effect of consumption of a wheat-flour bread-based low-fibre diet (7.8 g/day fibre; 1.0 portion) or the same diet in which the wheat bread was exchange for a bread based on oat bran with a high fibre content (31.9 g/day fibre; 1.0 portion) on the ileal excretion of amino acid residues and crude protein w...

    journal_title：European journal of clinical nutrition

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：

    authors： Abrahamsson M,Aman P,Hallmans G,Zhang JX,Tidehag P

    更新日期：1995-08-01 00:00:00

  • Effects of two different types of fast food on postprandial metabolism in normal and overweight subjects.

    abstract：BACKGROUND/OBJECTIVES:The aim was to investigate the effects of a conventional and an unconventional fast-food meal on postprandial metabolism in normal and in overweight subjects. SUBJECTS/METHODS:Twenty-five healthy normal (n = 12) and overweight (n = 13) volunteers (21-39 years) participated in this randomized, die...

    journal_title：European journal of clinical nutrition

    pub_type： 杂志文章,随机对照试验

    doi：10.1038/ejcn.2012.125

    authors： Ramel A,Gudmundsdottir FD,Thorsdottir I

    更新日期：2012-11-01 00:00:00

  • Early first trimester maternal 'high fish and olive oil and low meat' dietary pattern is associated with accelerated human embryonic development.

    abstract：BACKGROUND/OBJECTIVES:Maternal dietary patterns were associated with embryonic growth and congenital anomalies. We aim to evaluate associations between early first trimester maternal dietary patterns and embryonic morphological development among pregnancies with non-malformed outcome. SUBJECTS/METHODS:A total of 228 s...

    journal_title：European journal of clinical nutrition

    pub_type： 杂志文章

    doi：10.1038/s41430-018-0161-7

    authors： Parisi F,Rousian M,Steegers-Theunissen RPM,Koning AHJ,Willemsen SP,de Vries JHM,Cetin I,Steegers EAP

    更新日期：2018-12-01 00:00:00

  • On the importance of processing conditions, product thickness and egg addition for the glycaemic and hormonal responses to pasta: a comparison with bread made from 'pasta ingredients'.

    abstract：:The importance of processing conditions, product thickness and effect of egg addition for the glycaemic and hormonal responses to pasta was studied. Healthy subjects were given test meals with an equivalent amount of available carbohydrate from extruded high-temperature dried spaghetti and three varieties of fresh rol...

    journal_title：European journal of clinical nutrition

    pub_type： 杂志文章

    doi：

    authors： Granfeldt Y,Björck I,Hagander B

    更新日期：1991-10-01 00:00:00

  • Operationalization of food consumption surveys in Europe: recommendations from the European Food Consumption Survey Methods (EFCOSUM) Project.

    abstract：BACKGROUND:The EFCOSUM (European Food Consumption Survey Methods) Project aims at harmonizing food consumption surveys in European countries within the perspective of an overall Public Health Monitoring Programme. Harmonization implies the need for a common framework of procedures and tools, that are applicable and fea...

    journal_title：European journal of clinical nutrition

    pub_type： 杂志文章

    doi：10.1038/sj.ejcn.1601431

    authors： De Henauw S,Brants HA,Becker W,Kaic-Rak A,Ruprich J,Sekula W,Mensink GB,Koenig JS,EFCOSUM Group.

    更新日期：2002-05-01 00:00:00

  • Long-term effects of a plant-based dietary portfolio of cholesterol-lowering foods on blood pressure.

    abstract：OBJECTIVE:To determine the effect on blood pressure of dietary advice to consume a combination of plant-based cholesterol-lowering foods (dietary portfolio). METHODS:For 1 year, 66 hyperlipidemic subjects were prescribed diets high in plant sterols (1.0 g/1000 kcal), soy protein (22.5 g/1000 kcal), viscous fibers (10 ...

    journal_title：European journal of clinical nutrition

    pub_type： 杂志文章,随机对照试验

    doi：10.1038/sj.ejcn.1602768

    authors： Jenkins DJ,Kendall CW,Faulkner DA,Kemp T,Marchie A,Nguyen TH,Wong JM,de Souza R,Emam A,Vidgen E,Trautwein EA,Lapsley KG,Josse RG,Leiter LA,Singer W

    更新日期：2008-06-01 00:00:00

  • Trends of increases in potential risk factors and prevalence rates of diabetes mellitus in Thailand.

    abstract：:Over the past three decades, undernutrition in Thailand has drastically reduced by over seven times. However, since 1995 the number of patients afflicted with non-communicable diseases, such as diabetes mellitus, has rapidly increased, even among the young. Unhealthy life styles due to urbanization are a major reason ...

    journal_title：European journal of clinical nutrition

    pub_type： 杂志文章,评审

    doi：10.1038/ejcn.2017.52

    authors： Chavasit V,Kriengsinyos W,Photi J,Tontisirin K

    更新日期：2017-07-01 00:00:00

  • Body fat distribution and noncommunicable diseases in populations: overview of the 2008 WHO Expert Consultation on Waist Circumference and Waist-Hip Ratio.

    abstract：:A World Health Organization (WHO) Expert Consultation on Waist Circumference (WC) and Waist-Hip Ratio (WHR) was convened in Geneva from 8 to 11 December 2008 to consider approaches to developing international guidelines for indices and action levels in order to characterize health risks associated with these measures ...

    journal_title：European journal of clinical nutrition

    pub_type：

    doi：10.1038/ejcn.2009.139

    authors： Nishida C,Ko GT,Kumanyika S

    更新日期：2010-01-01 00:00:00

  • Dietary intervention in breast cancer patients: effects on dietary habits and nutrient intake.

    abstract：:Effects of dietary intervention on dietary habits and nutrient levels were studied in 240 women aged 50-65 years who had been operated for a stage I-II breast cancer. Following surgery the women who had participated in a dietary history interview were randomly assigned to one of two groups. The intervention group (n =...

    journal_title：European journal of clinical nutrition

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：

    authors： Nordevang E,Ikkala E,Callmer E,Hallström L,Holm LE

    更新日期：1990-09-01 00:00:00

  • Predictors of body composition changes during tuberculosis treatment in Mwanza, Tanzania.

    abstract：BACKGROUND/OBJECTIVES:Gains in fat mass and lean mass during tuberculosis (TB) treatment may determine functional recovery and survival; yet, data are scarce. We aimed to assess predictors of fat and fat-free mass during 2 months of intensive TB treatment in a cohort in Mwanza, Tanzania. SUBJECTS/METHODS:Fat and fat-f...

    journal_title：European journal of clinical nutrition

    pub_type： 杂志文章

    doi：10.1038/ejcn.2015.37

    authors： PrayGod G,Range N,Faurholt-Jepsen D,Jeremiah K,Faurholt-Jepsen M,Aabye MG,Magnussen P,Changalucha J,Andersen AB,Wells JC,Friis H

    更新日期：2015-10-01 00:00:00

  • Body fatness and frame size: the Caerphilly study.

    abstract：:The effect of adjusting height-weight indices for frame size on the prediction of body fatness was investigated in a community sample of 2512 men aged 45-59 years. Body fatness was assessed from skinfold thickness measurements at four sites: triceps, biceps, subscapular and supra-iliac. Body diameters (biacromial, bi-...

    journal_title：European journal of clinical nutrition

    pub_type： 杂志文章

    doi：

    authors： Fehily AM,Butland BK,Yarnell JW

    更新日期：1990-02-01 00:00:00

  • Effect of multiple micronutrient-fortified food on mild morbidity and clinical symptoms in Zambian infants: results from a randomised controlled trial.

    abstract：BACKGROUND/OBJECTIVES:We aimed to assess the effects on mild morbidity of a richly micronutrient-fortified complementary/replacement food given to Zambian infants aged 6-18 months. Previous results (The Chilenje Infant Growth, Nutrition and Infection Study Team, 2010) showed an increase in the rate of hospital referral...

    journal_title：European journal of clinical nutrition

    pub_type： 杂志文章,随机对照试验

    doi：10.1038/ejcn.2011.103

    authors： Manno D,Siame J,Larke N,Baisley K,Kasonka L,Filteau S

    更新日期：2011-10-01 00:00:00

  • Relationship between a wide range of alcohol consumptions, components of the insulin-like growth factor system and adiponectin.

    abstract：OBJECTIVE:To explore the relation between a wide range of alcohol consumptions and levels of the components of insulin-like growth factor system (IGFs) and adiponectin in humans. DESIGN:A cross-sectional study using controls from a case-control study on ovarian and endometrial cancer. SETTINGS:The study included wome...

    journal_title：European journal of clinical nutrition

    pub_type： 杂志文章

    doi：10.1038/sj.ejcn.1602519

    authors： Dal Maso L,La Vecchia C,Augustin LS,Mantzoros CS,Kendall CW,Franceschi S

    更新日期：2007-02-01 00:00:00

  • The implication of the binomial nutrition-immunity on sportswomen's health.

    abstract：:The diet of many athletes is inadequate due to overly restrictive habits and an obsession with losing weight in order to maintain a particular level of body weight. Many female athletes, particularly those who participate in sports that emphasize leanness (gymnastics, distance running, diving, figure skating and class...

    journal_title：European journal of clinical nutrition

    pub_type： 杂志文章,评审

    doi：10.1038/sj.ejcn.1601483

    authors： Montero A,López-Varela S,Nova E,Marcos A

    更新日期：2002-08-01 00:00:00

  • Malnutrition in women with rheumatoid arthritis is not revealed by clinical anthropometrical measurements or nutritional evaluation tools.

    abstract：OBJECTIVE:To evaluate diagnostic instruments for assessment of nutritional status in patients with rheumatoid arthritis (RA) in relation to objective body composition data. SUBJECTS AND METHODS:Study subjects include 60 in-ward patients (83% women, median age 65 years). Anthropometric measures and the nutritional tool...

    journal_title：European journal of clinical nutrition

    pub_type： 杂志文章

    doi：10.1038/sj.ejcn.1602845

    authors： Elkan AC,Engvall IL,Tengstrand B,Cederholm T,Hafström I

    更新日期：2008-10-01 00:00:00

  • Single measurement of serum 25(OH)D: is classification into month-specific cutpoints useful in accounting for seasonal variation?

    abstract：:Classification into month-specific cutpoints is used to minimize misclassification associated with single measurement of serum 25(OH)D. This study aims to evaluate this strategy, and to compare it with the widely used classification into overall cutpoints. For this purpose, we studied 69,553 subjects in whom serum 25(...

    journal_title：European journal of clinical nutrition

    pub_type： 杂志文章

    doi：10.1038/ejcn.2012.69

    authors： Saliba W,Barnett-Griness O,Rennert G

    更新日期：2012-09-01 00:00:00

  • Dietary phosphorus intake estimated by 4-day dietary records and two 24-hour urine collections and their associated factors in Japanese adults.

    abstract：BACKGROUND/OBJECTIVES:Both self-reported dietary information and urinary excretion have limitations in the assessment of phosphorus intake. We conducted a cross-sectional study to estimate dietary phosphorus intake by dietary records (DR) and 24-h urine collections (UC) and examined associated factors. SUBJECTS/METHOD...

    journal_title：European journal of clinical nutrition

    pub_type： 杂志文章

    doi：10.1038/s41430-018-0114-1

    authors： Shinozaki N,Murakami K,Asakura K,Uechi K,Kobayashi S,Masayasu S,Sasaki S

    更新日期：2018-04-01 00:00:00

  • Pregnancy and lactation in relation to range of acceptable carbohydrate and fat intake.

    abstract：:The additional energy requirements of pregnancy are needed for increases in maternal (breast, uterus and adipose) and feto-placental tissue accrued during pregnancy as well as the additional running cost of pregnancy for example increased cardiac output. Based on prospective longitudinal studies, the additional energy...

    journal_title：European journal of clinical nutrition

    pub_type： 杂志文章,评审

    doi：10.1038/sj.ejcn.1600753

    authors： Catalano PM

    更新日期：1999-04-01 00:00:00

  • Validity of nutritional screening with MUST and SNAQ in hospital outpatients.

    abstract：BACKGROUND/OBJECTIVES:The majority of hospital outpatients with undernutrition is unrecognized, and therefore untreated. There is a need for an easy and valid screening tool to detect undernutrition in this setting. The aim of this study was to determine the diagnostic accuracy of the MUST (Malnutrition Universal Scree...

    journal_title：European journal of clinical nutrition

    pub_type： 杂志文章,多中心研究

    doi：10.1038/ejcn.2013.85

    authors： Leistra E,Langius JA,Evers AM,van Bokhorst-de van der Schueren MA,Visser M,de Vet HC,Kruizenga HM

    更新日期：2013-07-01 00:00:00

  • Bioavailability of starch in bread rich in amylose: metabolic responses in healthy subjects and starch structure.

    abstract：OBJECTIVE:This study investigated whether postprandial metabolic responses to bread could be lowered by substituting high amylose maize starch for a part of the flour. DESIGN AND SUBJECTS:Eight healthy subjects consumed test meals of equivalent nutritional composition based on white wheat bread, bread rich in amylose ...

    journal_title：European journal of clinical nutrition

    pub_type： 杂志文章

    doi：10.1038/sj.ejcn.1600718

    authors： Hoebler C,Karinthi A,Chiron H,Champ M,Barry JL

    更新日期：1999-05-01 00:00:00

  • Comparison of nutrient intake data calculated on the basis of two different databases. Results and experiences from a Swedish-Finnish study.

    abstract：BACKGROUND AND OBJECTIVE:In international surveys of food consumption and nutrient intake, it is essential that the dietary data are comparable when different databases and calculation programs are used. The aim of the present analysis was to examine the comparability of nutrient intake data calculated on the basis of ...

    journal_title：European journal of clinical nutrition

    pub_type： 杂志文章

    doi：10.1038/sj.ejcn.1601639

    authors： Hakala P,Knuts LR,Vuorinen A,Hammar N,Becker W

    更新日期：2003-09-01 00:00:00

  • Low body weight and its association with bone health and pubertal maturation in Chinese girls.

    abstract：OBJECTIVE:To investigate the prevalence of low body weight in Beijing pubertal girls and to establish the cut-off for body mass index (BMI) for underweight for Chinese pubertal girls. DESIGN:Cross-sectional study. SETTING:Three socioeconomic areas (rural, suburban and urban) in Beijing, China. SUBJECTS:Random sample...

    journal_title：European journal of clinical nutrition

    pub_type： 杂志文章

    doi：10.1038/sj.ejcn.1601599

    authors： Du X,Greenfield H,Fraser DR,Ge K,Zheng W,Huang L,Liu Z

    更新日期：2003-05-01 00:00:00

  • Swedish obese subjects (SOS): an obesity intervention study with a nutritional perspective.

    abstract：OBJECTIVES:Swedish Obese Subjects (SOS) is a multidisciplinary project involving aspects of obesity ranging from description of the severely obese state to effects of surgical intervention on long-term mortality and morbidity. Dietary studies, which represent an integral part of SOS research activities, are the focus o...

    journal_title：European journal of clinical nutrition

    pub_type： 杂志文章,评审

    doi：10.1038/sj.ejcn.1600567

    authors： Lissner L,Lindroos AK,Sjöström L

    更新日期：1998-05-01 00:00:00

  • Carotenoderma in a young woman of normal body mass index with hypothalamic amenorrhoea: a 2-year follow-up case report.

    abstract：:Hypothalamic amenorrhoea has been shown to be associated with hypercarotenaemia, but no causal link has been established. Many people are unaware of the health implications of carotenoderma. We report on a 36-year-old woman with normal body mass index and with a history of secondary amenorrhoea for 2 years and caroten...

    journal_title：European journal of clinical nutrition

    pub_type： 杂志文章

    doi：10.1038/ejcn.2014.128

    authors： Nyekiova M,Ghaderi S,Han TS

    更新日期：2014-12-01 00:00:00

  • Fasting and glucose induced thermogenesis in response to three ambient temperatures: a randomized crossover trial in the metabolic syndrome.

    abstract：BACKGROUND/OBJECTIVES:Cold exposure increases thermogenesis and could improve insulin sensitivity. We hypothesized a blunted response in the metabolic syndrome (MetS). SUBJECTS/METHODS:Twenty older adults 59 ± 10.4 years (with MetS, MetS+, n = 9; without MetS, MetS-, n = 11) completed a randomized crossover design of ...

    journal_title：European journal of clinical nutrition

    pub_type： 杂志文章,随机对照试验

    doi：10.1038/s41430-017-0058-x

    authors： Pathak K,Woodman RJ,James AP,Soares MJ

    更新日期：2018-10-01 00:00:00

  • Exploring inter-organ crosstalk to uncover mechanisms that regulate β-cell function and mass.

    abstract：:Impaired β-cell function and insufficient β-cell mass compensation are twin pathogenic features that underlie type 2 diabetes (T2D). Current therapeutic strategies continue to evolve to improve treatment outcomes in different ethnic populations and include approaches to counter insulin resistance and improve β-cell fu...

    journal_title：European journal of clinical nutrition

    pub_type： 杂志文章,评审

    doi：10.1038/ejcn.2017.13

    authors： Shirakawa J,De Jesus DF,Kulkarni RN

    更新日期：2017-07-01 00:00:00

  • Web-based eHealth applications with reference to food composition data.

    abstract：BACKGROUND/OBJECTIVES:Food composition data (FCD) can provide important information in relation to diet and health; therefore, data on food composition have broad applications in health care. The objective of this study was to provide an overview of added-value eHealth systems that use modern information and communicat...

    journal_title：European journal of clinical nutrition

    pub_type： 杂志文章

    doi：10.1038/ejcn.2010.222

    authors： Koroušić Seljak B

    更新日期：2010-11-01 00:00:00

  • Poor complementary feeding practices and high anaemia prevalence among infants and young children in rural central and western China.

    abstract：BACKGROUND/OBJECTIVES:Infant and young child feeding (IYCF) has not been documented in central and western China, where anaemia is prevalent. To support policy advocacy, we assessed IYCF and anaemia there using standardized methods. SUBJECTS/METHODS:A community-based, cross-sectional survey of 2244 children aged 6-23 ...

    journal_title：European journal of clinical nutrition

    pub_type： 杂志文章

    doi：10.1038/ejcn.2014.98

    authors： Hipgrave DB,Fu X,Zhou H,Jin Y,Wang X,Chang S,Scherpbier RW,Wang Y,Guo S

    更新日期：2014-08-01 00:00:00

  • Associations between neighbourhood characteristics, body mass index and health-related behaviours of adolescents in the Kiel Obesity Prevention Study: a multilevel analysis.

    abstract：BACKGROUND/OBJECTIVES:To understand determinants of overweight, several studies addressed the association between neighbourhood characteristics and adult obesity. However, little is known about the association of such characteristics with adolescents' overweight. This study aims at the influence of neighbourhood charac...

    journal_title：European journal of clinical nutrition

    pub_type： 杂志文章

    doi：10.1038/ejcn.2011.21

    authors： Lange D,Wahrendorf M,Siegrist J,Plachta-Danielzik S,Landsberg B,Müller MJ

    更新日期：2011-06-01 00:00:00

  • Rye bread decreases postprandial insulin response but does not alter glucose response in healthy Finnish subjects.

    abstract：OBJECTIVE:To compare if postprandial glucose and insulin responses to wholekernel rye bread are lower than to wheat bread, and to see if these responses to two types of rye breads are different. To explore starch digestion in more detail, rate of starch hydrolysis of same breads was measured in vitro. DESIGN:Subjects ...

    journal_title：European journal of clinical nutrition

    pub_type： 杂志文章

    doi：10.1038/sj.ejcn.1600716

    authors： Leinonen K,Liukkonen K,Poutanen K,Uusitupa M,Mykkänen H

    更新日期：1999-04-01 00:00:00