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Cutaneous sympathetic function and cardiovascular function in patients with progressive supranuclear palsy and Parkinson's disease.

Abstract：

:Some procedures, such as deep inspiration, increase sweat output (SSwR; sympathetic sweat response) and reduce cutaneous blood flow (SVR; skin vasomotor reflex) on the palm. We investigated SSwR, SVR, and cardiovascular function in 12 patients with progressive supranuclear palsy (PSP), 13 patients with Parkinson's disease (PD), and 9 healthy subjects. In the PSP patients, SSwR was severely diminished, whereas SVR was maintained and cardiovascular function was well preserved. In the PD patients, SSwR was relatively preserved, SVR was maintained, and some patients showed cardiovascular hypofunction. A combination of skin sympathetic and cardiovascular tests may be useful for distinguishing between PD and PSP.

journal_name

Parkinsonism Relat Disord

journal_title

Parkinsonism & related disorders

authors

Kikkawa Y,Asahina M,Suzuki A,Hattori T

doi

10.1016/s1353-8020(03)00109-3

subject

Has Abstract

pub_date

2003-12-01 00:00:00

pages

101-6

issue

2

eissn

1353-8020

issn

1873-5126

pii

S1353802003001093

journal_volume

10

pub_type

杂志文章

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