Successful withdrawal of long-term epoprostenol therapy for pulmonary arterial hypertension.

abstract：:What is the meaning of these findings to the practicing chest physician? First, leukotrienes are potent airway constrictors; they are capable of reproducing the type of airway constriction observed in asthma. The role of leukotrienes in this regard has yet to be established, but experiments to test the importance of t...

journal_title：Chest

authors： Drazen JM

更新日期：1986-03-01 00:00:00

abstract：BACKGROUND:Methicillin-resistant Staphylococcus aureus (MRSA) is a leading cause of hospital-acquired pneumonia (HAP), ventilator-associated pneumonia (VAP), and health-care-associated pneumonia (HCAP). These infections are associated with significant morbidity, mortality, and cost. The impact of vancomycin minimum inh...

journal_title：Chest

authors： Haque NZ,Zuniga LC,Peyrani P,Reyes K,Lamerato L,Moore CL,Patel S,Allen M,Peterson E,Wiemken T,Cano E,Mangino JE,Kett DH,Ramirez JA,Zervos MJ,Improving Medicine through Pathway Assessment of Critical Therapy of Hospital-Acqu

更新日期：2010-12-01 00:00:00

abstract：BACKGROUND:The effects of regular inhaled beta-agonist treatment on lung function remain a controversial issue. In an earlier study, the administration of regular inhaled salbutamol resulted in negative changes in FEV1 not only in asthmatics, but also in nonasthmatic atopic subjects. OBJECTIVE:The aim of this study wa...

journal_title：Chest

authors： Boothman-Burrell D,Jones D,Herbison GP,Taylor DR

更新日期：1997-07-01 00:00:00

abstract：BACKGROUND:Induced sputum cytology and protein biomarkers can be used to assess airways inflammation. Increases in sputum iron have been described in inflammatory lung disease. We hypothesized that other sputum metals may be affected by airways inflammation and investigated their potential value as biomarkers. METHODS...

journal_title：Chest

authors： Gray RD,Duncan A,Noble D,Imrie M,O'Reilly DS,Innes JA,Porteous DJ,Greening AP,Boyd AC

更新日期：2010-03-01 00:00:00

abstract：STUDY OBJECTIVE:To study mechanisms of gastroesophageal reflux-induced bronchoconstriction during intraesophageal infusions. DESIGN:Prospective study blinded to the subject. SETTING:Outpatient pulmonary function laboratory at a 908-bed university hospital. PARTICIPANTS:Forty-seven adult subjects divided into four gr...

journal_title：Chest

authors： Schan CA,Harding SM,Haile JM,Bradley LA,Richter JE

更新日期：1994-09-01 00:00:00

abstract：BACKGROUND:In pulmonary sarcoidosis, the optimal means of quantifying change is uncertain. The comparative usefulness of simple lung function trends and chest radiography remains unclear. We aimed to explore and contrast the disease-monitoring strategies of serial pulmonary function tests (PFTs) and chest radiography c...

journal_title：Chest

authors： Zappala CJ,Desai SR,Copley SJ,Spagnolo P,Sen D,Alam SM,du Bois RM,Hansell DM,Wells AU

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVES:To determine whether certain occupations and occupationally related exposures were associated with a history of sarcoidosis in African-American siblings. METHODS:We collected occupational data from 921 African Americans in 273 sibships that had been identified through a sarcoidosis case. Among the 648 sibli...

journal_title：Chest

authors： Kucera GP,Rybicki BA,Kirkey KL,Coon SW,Major ML,Maliarik MJ,Iannuzzi MC

更新日期：2003-05-01 00:00:00

abstract：:Every year, millions of patients are diagnosed with pulmonary nodules, and as increasing numbers of people undergo lung cancer screening, even more patients will be found to have a nodule. The vast majority of patients cannot benefit from the detection of a pulmonary nodule because most are benign. Accordingly, it is ...

journal_title：Chest

authors： Slatore CG,Wiener RS

更新日期：2018-04-01 00:00:00

abstract：:We describe a patient who suffered from a bacterial pneumonia and had a left-sided infiltrate on his chest radiograph. He was found to be cytopenic and acute myeloid leukemia was diagnosed. A complete remission was achieved after chemotherapy, and the patient was scheduled to have autologous bone marrow transplantatio...

journal_title：Chest

authors： Sutedja T,Kwa B,van Kamp H,van Zandwijk N

更新日期：1993-06-01 00:00:00

abstract：BACKGROUND:Whether the localization of nonmassive pulmonary embolism (PE) is associated with the short-term and long-term prognosis of patients remains unknown. Our aim was to characterize associations of nonmassive PE localization with risks of recurrent VTE, major bleeding, and mortality during and after anticoagulat...

journal_title：Chest

authors： Gouin B,Blondon M,Jiménez D,Fernández-Capitán C,Bounameaux H,Soler S,Duce R,Sahuquillo JC,Ruiz-Giménez N,Monreal M,RIETE investigators.

更新日期：2017-04-01 00:00:00

abstract：:Fine-needle aspiration biopsy of the spleen was carried out in 557 patients. In 381 cases, the aspiration was performed because of suspected sarcoidosis. The sensitivity of the technique was 59 percent and the specificity 97 percent. The cytologic picture of the spleen was abnormal in 184 patients with sarcoidosis and...

journal_title：Chest

authors： Selroos O,Koivunen E

更新日期：1983-02-01 00:00:00

abstract：BACKGROUND:Bosentan, an oral endothelin (ET)-A/ET-B receptor antagonist, is effective in the treatment of pulmonary arterial hypertension. OBJECTIVE:To investigate the safety and efficacy of bosentan therapy in patients with inoperable chronic thromboembolic pulmonary hypertension (CTEPH). DESIGN:Case series. SETTIN...

journal_title：Chest

authors： Bonderman D,Nowotny R,Skoro-Sajer N,Jakowitsch J,Adlbrecht C,Klepetko W,Lang IM

更新日期：2005-10-01 00:00:00

abstract：:In vitro cell-mediated immunity was examined in patients infected with nontuberculous mycobacteria, Mycobacterium avium-intracellulare complex in Japan. Peripheral blood lymphocytes of patients, as compared with those of tuberculous patients or tuberculin-positive healthy donors, showed depressed in vitro blastogenic ...

journal_title：Chest

authors： Tsuyuguchi I,Shiratsuchi H,Okuda Y,Yamamoto Y

更新日期：1988-10-01 00:00:00

abstract：BACKGROUND:Little is known about factors determining the pathogenesis and severity of asthma in Latin American countries. Costa Rica, one of the most prosperous Latin American nations, has a very high asthma prevalence. OBJECTIVE:To examine the relation between potential risk factors and childhood asthma in Costa Rica...

journal_title：Chest

authors： Celedón JC,Soto-Quiros ME,Silverman EK,Hanson L,Weiss ST

更新日期：2001-09-01 00:00:00

abstract：INTRODUCTION:The specific causes and mechanism(s) for asthma occurring among occupants of non-residential buildings with poor indoor air quality are not known, but allergic and nonallergic processes are possible explanations METHODS:Repeated indoor air quality measurements were made while employees were working in a b...

journal_title：Chest

authors： Brooks SM,Spaul W,McCluskey JD

更新日期：2005-09-01 00:00:00

abstract：STUDY OBJECTIVES:We investigated the role of two leukotriene B4 (LTB4) receptors, BLT1 and peroxisome proliferator-activated receptor (PPAR)-alpha, in conferring the susceptibility to develop COPD in smokers. Proinflammatory LTB4 activities are mediated by BLT1, while the inactivation of LTB4 is promoted by PPARalpha. ...

journal_title：Chest

authors： Marian E,Baraldo S,Visentin A,Papi A,Saetta M,Fabbri LM,Maestrelli P

更新日期：2006-06-01 00:00:00

abstract：STUDY OBJECTIVES:To measure the prevalence of exercise-induced bronchospasm (EIB) and to determine its effect on the physical performance response to training in otherwise healthy young adults. DESIGN:Observational, retrospective study. SETTING:Fort Jackson, SC, May to July 1998. PARTICIPANTS:One hundred thirty-seve...

journal_title：Chest

authors： Sonna LA,Angel KC,Sharp MA,Knapik JJ,Patton JF,Lilly CM

更新日期：2001-06-01 00:00:00

abstract：BACKGROUND:This study reports the effect of thoracentesis on respiratory mechanics and gas exchange in patients receiving mechanical ventilation. STUDY DESIGN:Prospective. SETTING:University hospital. PATIENTS:Eight patient receiving mechanical ventilation with unilateral (n = 7) or bilateral (n = 1) large pleural e...

journal_title：Chest

authors： Doelken P,Abreu R,Sahn SA,Mayo PH

更新日期：2006-11-01 00:00:00

abstract：:The measurement of the activity of acid hydrolases and of alkaline phosphatase in bronchial aspirates obtained through bronchoscopic procedures from a series of 300 patients forms the basis for a screening program to diagnose bronchial malignant neoplasms more effectively. We define such a screening test as one permit...

journal_title：Chest

authors： Kühn SH,de Kock MA,Gevers W

更新日期：1978-08-01 00:00:00

abstract：OBJECTIVES:To report observations on preserved regular atrial electrical and mechanical systole during ventricular fibrillation (VF) and to quantitate blood flow generated by atrial contractions in this setting. METHODS:In 10 rats, right atrial pressure pulses were continuously recorded before and for an interval of 8...

journal_title：Chest

authors： Pernat A,Weil MH,Sun S,Tang W,Yamaguchi H,Bisera J

更新日期：2000-04-01 00:00:00

abstract：:A 79-year-old woman in the course of a syncope evaluation is shown to have a trazodone-related cardiac arrhythmia confirmed by drug rechallenge. This nontricyclic antidepressant should be considered as potentially arrhythmogenic despite its generally favorable cardiovascular profile. ...

journal_title：Chest

authors： Vitullo RN,Wharton JM,Allen NB,Pritchett EL

更新日期：1990-07-01 00:00:00

abstract：:Widespread use of thrombolytic agents in a variety of settings has highlighted the need for measures of safety and efficacy. Previously used laboratory parameters, such as decreasing levels of fibrinogen and increasing levels of fibrin(ogen) degradation products (FDPs), have failed to correlate consistently with hemor...

journal_title：Chest

authors： Hirsch DR,Goldhaber SZ

更新日期：1990-04-01 00:00:00

abstract：:Fatal pulmonary embolism (PE) is a major cause of mortality in patients with spinal cord injury. In order to ascertain those characteristics that might predict this event, we reviewed the records of all patients with autopsy-proven massive PE admitted to a regional spinal cord care center over a 5-year period. The inf...

journal_title：Chest

authors： Green D,Twardowski P,Wei R,Rademaker AW

更新日期：1994-03-01 00:00:00

abstract：BACKGROUND:Portable monitoring is a convenient means for diagnosing sleep apnea. However, data on whether one night of monitoring is sufficiently precise for the diagnosis of sleep apnea are limited. RESEARCH QUESTION:The current study sought to determine the variability and misclassification in disease severity over ...

journal_title：Chest

authors： Punjabi NM,Patil S,Crainiceanu C,Aurora RN

更新日期：2020-07-01 00:00:00

abstract：:Due to concerns about the efficacy and safety of using pulmonary artery catheterization to evaluate hemodynamic status, noninvasive diagnostic testing has gained increased importance. This article focuses on both the supportive evidence and the limitations of applying the vascular pedicle width (VPW), which is the med...

journal_title：Chest

authors： Ely EW,Haponik EF

更新日期：2002-03-01 00:00:00

abstract：:Twenty-two consecutive patients underwent esophageal stimulation and recording for the diagnosis and management of supraventricular tachycardia. In 13 of these patients, the resting electrocardiogram was normal and in nine it showed pre-excitation. Of the 13 patients with a normal resting electrocardiogram, supraventr...

journal_title：Chest

authors： Harte MT,Teo KK,Horgan JH

更新日期：1988-02-01 00:00:00

abstract：BACKGROUND:Sleep-disordered breathing (SDB) may promote an increase in cardiac workload early after acute myocardial infarction (AMI). We tested the hypothesis that in the early phase after AMI, SDB is associated with increased 24-h arterial BP, heart rate (HR), and, thus, cardiac workload. METHODS:In this prospective...

journal_title：Chest

authors： Hetzenecker A,Buchner S,Greimel T,Satzl A,Luchner A,Debl K,Husser O,Hamer OW,Fellner C,Riegger GAJ,Pfeifer M,Arzt M

更新日期：2013-05-01 00:00:00

abstract：BACKGROUND:Although the cycle ergometer is the traditional mode for exercise testing in patients with respiratory disease, this preference over the treadmill does not consider perceptual responses. Our hypotheses were as follows: (1) the regression slope between breathlessness and oxygen consumption (Vo(2)) is greater ...

journal_title：Chest

authors： Murray JA,Waterman LA,Ward J,Baird JC,Mahler DA

更新日期：2009-02-01 00:00:00

abstract：:Tube thoracostomy is an invasive procedure that carries a risk of complications. We report a patient with liver cirrhosis, ascites and large left-sided pleural effusion, in whom a trocar type chest tube was inserted at the seventh left intercostal space in the midaxillary line. Chest roentgenogram revealed that the dr...

journal_title：Chest

authors： Foresti V,Villa A,Casati O,Parisio E,De Filippi G

更新日期：1992-07-01 00:00:00

abstract：:Sleep health is a multidimensional construct that includes adequate duration, quality, and appropriately timed sleep that may be influenced by environmental factors. In this review, we focus on how an individual's living and sleeping environment, both the surrounding neighborhood physical and social features and the a...

journal_title：Chest

authors： Billings ME,Hale L,Johnson DA

更新日期：2020-05-01 00:00:00