Abstract:
:To evaluate the role of adrenal androgens in the development of arteriosclerosis, serum dehydroepiandrosterone sulfate (DHEAS), dehydroepiandrosterone (DHEA), aortic calcification and pulse wave velocity (PWV) were measured in 69 males and 119 females without overt cardiovascular disease. The steroids decreased with age in both sexes, and the reduction was significantly steeper in younger (< or = 40 years) than in older (> 40 years) subjects only in females. When adjusted for age, the steroids were significantly lower in subjects with aortic calcification than in those without it, and the PWV was significantly slower in the latter. Adrenal androgens appear to retard the development and/or progression of arteriosclerosis.
journal_name
Cardiologyjournal_title
Cardiologyauthors
Ishihara F,Hiramatsu K,Shigematsu S,Aizawa T,Niwa A,Takasu N,Yamada T,Matsuo Kdoi
10.1159/000175022subject
Has Abstractpub_date
1992-01-01 00:00:00pages
332-8issue
5-6eissn
0008-6312issn
1421-9751journal_volume
80pub_type
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