The use of low-dose insulin in cardiogenic shock due to combined overdose of verapamil, enalapril and metoprolol.

Abstract:

:We describe a case of severe heart failure due to the combined effect of verapamil and enalapril overdose in a patient treated regularly with metoprolol. The patient was dependent for 2 days on glucagon and dopamine infusion but remained oliguric, with deteriorating renal function. Marked improvement in all hemodynamic parameters was noted a short time after initiation of treatment with low-dose insulin infusion (1-2 units/h), which allowed the prompt withdrawal of glucagon and dopamine. We discuss the efficacy of glucose-insulin treatment in toxic cardiac depression and suggest that a low dose may be beneficial in similar cases.

journal_name

Cardiology

journal_title

Cardiology

authors

Hasin T,Leibowitz D,Antopolsky M,Chajek-Shaul T

doi

10.1159/000093191

subject

Has Abstract

pub_date

2006-01-01 00:00:00

pages

233-6

issue

4

eissn

0008-6312

issn

1421-9751

pii

93191

journal_volume

106

pub_type

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