The role of induced sputum in amiodarone-associated interstitial lung diseases.

Abstract:

:Amiodarone, a highly effective medication for suppressing cardiac rhythm disturbances, may cause pulmonary injury, such as chronic interstitial lung diseases, in 5-15% of the patients who take it. We applied induced sputum (IS), a non-invasive technique, for diagnosing amiodarone-induced pulmonary toxicity. Four patients with interstitial lung disease who were treated by amiodarone for ischemic heart diseases were evaluated by a conventional clinical workup. All four patients showed marked interstitial pattern on computerized tomography and decreased diffusion capacity (DLCO-SB 51-76%). IS showed lymphocytosis, a high CD4 or CD8 count, eosinophilia and amiodarone in 3 of 4 patients. IS may be a useful tool for assessing amiodarone toxicity in patients with ischemic heart diseases and concomitant pulmonary side effects.

journal_name

Cardiology

journal_title

Cardiology

authors

Fireman E,Topilsky I,Viskin S,Priel IE

doi

10.1159/000096782

subject

Has Abstract

pub_date

2007-01-01 00:00:00

pages

223-7

issue

4

eissn

0008-6312

issn

1421-9751

pii

96782

journal_volume

108

pub_type

临床试验,杂志文章
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    pub_type: 杂志文章

    doi:10.1159/000006905

    authors: Fuchs S,Pollak A,Gilon D

    更新日期:1999-01-01 00:00:00

  • OPG/RANK/RANKL axis in stabilization of spontaneously restored sinus rhythm in permanent atrial fibrillation patients after mitral valve surgery.

    abstract:OBJECTIVE:To investigate the expression of the osteoprotegerin (OPG)/receptor activator of nuclear factor-ĸB (RANK)/RANK ligand (RANKL) axis in the stabilization of spontaneously restored sinus rhythm (SR) in permanent atrial fibrillation (AF) patients after mitral valve (MV) surgery and study its clinical significance...

    journal_title:Cardiology

    pub_type: 杂志文章

    doi:10.1159/000342784

    authors: Xi L,Cao H,Zhu J,Røe OD,Li M,Wu Y,Wang D,Chen Y

    更新日期:2013-01-01 00:00:00

  • Viable but denervated right ventricular myocardium: a case of Eisenmenger reaction.

    abstract::We report on a 47-year-old woman who experienced an Eisenmenger reaction (mean pulmonary artery pressure: 86 mm Hg) induced by atrial septal defect. Radionuclide myocardial scans with 99mTc-MIBI and 123I-BMIPP showed increased uptake to the right ventricular myocardium, whereas the 123I-MIBG scan disclosed no uptake t...

    journal_title:Cardiology

    pub_type: 杂志文章

    doi:10.1159/000177435

    authors: Hirose Y,Ishida Y,Hayashida K,Satoh T,Shimotsu Y,Nishimura T

    更新日期:1997-11-01 00:00:00

  • Cold pressure test producing coronary spasm, coronary thrombosis and myocardial infarction in a patient with IgM antibodies against Coxsackie B virus.

    abstract::Several lines of evidence have shown that viral infections are capable of causing coronary spasm and precipitating or mimicking clinical myocardial infarction. Here we report the case of a 41-year-old woman with recurrent angina who was admitted to our hospital because of ventricular tachycardia. Laboratory examinatio...

    journal_title:Cardiology

    pub_type: 杂志文章

    doi:10.1159/000006987

    authors: Haberbosch W,Roerich N,Neuzner J

    更新日期:1999-01-01 00:00:00

  • Valvular heart disease by transthoracic echocardiography is associated with focal brain injury and central neuropsychiatric systemic lupus erythematosus.

    abstract:BACKGROUND:Previous studies using transesophageal echocardiography (TEE) report an association of valvular heart disease (VHD) with cerebral infarcts and central neuropsychiatric systemic lupus erythematosus (NPSLE). However, TEE cannot be routinely used. AIM:To determine if VHD detected by transthoracic echocardiogra...

    journal_title:Cardiology

    pub_type: 杂志文章

    doi:10.1159/000099104

    authors: Roldan CA,Gelgand EA,Qualls CR,Sibbitt WL Jr

    更新日期:2007-01-01 00:00:00

  • Liver cirrhosis with ascites: pathogenesis of resistance to diuretics and long-term efficacy and safety of torasemide.

    abstract::In a prospective randomized short-term study, the efficacy and safety of xipamide and a combination of spironolactone and furosemide were compared in the treatment of hepatic cirrhotic ascites. Twenty-two patients were randomized to either xipamide, 20 mg/day (group I), or spironolactone, 200 mg/day, combined with fur...

    journal_title:Cardiology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1159/000176461

    authors: Knauf H,Mutschler E

    更新日期:1994-01-01 00:00:00

  • Fibrosis of collagen I and remodeling of connexin 43 in atrial myocardium of patients with atrial fibrillation.

    abstract:BACKGROUND:Fibrosis in atrial myocardium is a common phenomenon for patients with atrial fibrillation (AF). Remodeling of connexins was found accompanying with AF. The aim of the study is to investigate whether it is by causing the remodeling of connexin 43 (Cx43) that the fibrosis of atrial muscle plays an important r...

    journal_title:Cardiology

    pub_type: 杂志文章

    doi:10.1159/000095501

    authors: Luo MH,Li YS,Yang KP

    更新日期:2007-01-01 00:00:00

  • Radioisotopic renal function studies in essential hypertension.

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    journal_title:Cardiology

    pub_type: 杂志文章

    doi:10.1159/000173940

    authors: Britton KE

    更新日期:1985-01-01 00:00:00

  • Dyrk1A-ASF-CaMKIIδ Signaling Is Involved in Valsartan Inhibition of Cardiac Hypertrophy in Renovascular Hypertensive Rats.

    abstract:OBJECTIVES:It is known that the expression, activity and alternative splicing of Ca2+/calmodulin-dependent protein kinase IIδ (CaMKIIδ) are dysregulated in the cardiac remodeling process. Recently, we found a further signaling pathway, by which dual-specificity tyrosine phosphorylation-regulated kinase 1A (Dyrk1A) regu...

    journal_title:Cardiology

    pub_type: 杂志文章

    doi:10.1159/000441695

    authors: Yao J,Qin X,Zhu J,Sheng H

    更新日期:2016-01-01 00:00:00

  • Effect of autologous bone marrow cell transplantation combined with off-pump coronary artery bypass grafting on cardiac function in patients with chronic myocardial infarction.

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    journal_title:Cardiology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1159/000369381

    authors: Wang H,Wang Z,Jiang H,Ma D,Zhou W,Zhang G,Chen W,Huang J,Liu Y

    更新日期:2015-01-01 00:00:00

  • Syncope in dilated cardiomyopathy is a predictor of sudden cardiac death.

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    journal_title:Cardiology

    pub_type: 杂志文章

    doi:10.1159/000177083

    authors: Fruhwald FM,Eber B,Schumacher M,Zweiker R,Watzinger N,Klein WW

    更新日期:1996-05-01 00:00:00

  • Dilated cardiomyopathy: an unusual presentation of aortic coarctation in an infant.

    abstract::Coarctation of the aorta commonly presents in infancy as congestive heart failure, or later in childhood as hypertension or as a heart murmur. However, we experienced a unique infant case of isolated coarctation presenting with acute decompensation of a dilated cardiomyopathy, which recovered completely 8 months posto...

    journal_title:Cardiology

    pub_type: 杂志文章

    doi:10.1159/000092600

    authors: Hwang MS,Chu JJ,Chang YS,Su WJ

    更新日期:2006-01-01 00:00:00

  • Spatial and temporal variations in regional left ventricular function in isolated disease of the left anterior descending coronary artery.

    abstract::The temporal and spatial pattern of left ventricular (LV) contraction and relaxation in 34 patients with isolated lesions of the left anterior descending artery (LAD) were studied from the LV cineangiogram in the right anterior oblique position using a computer interactive technique. The LV outline was divided into 10...

    journal_title:Cardiology

    pub_type: 杂志文章

    doi:10.1159/000173980

    authors: Gotsman MS,Welber S,Sapoznikov D,Freiman I,Rosenman D,Lotan C

    更新日期:1986-01-01 00:00:00

  • Parameters of 99mTc-DTPA transfer function in renal artery stenosis.

    abstract::A new method is presented for decomposition of 99mTc-DTPA renal transfer functions (TF) into their capillary and tubular parts. Amplitudes and mean transit times of both parts were calculated and used for quantitative evaluation of renal perfusion, extraction and transport in 21 patients with renal artery stenosis. Th...

    journal_title:Cardiology

    pub_type: 杂志文章

    doi:10.1159/000173943

    authors: Szabó Z,Vosberg H,Torsello G,Sandmann W,Feinendegen LE

    更新日期:1985-01-01 00:00:00

  • Nitroprusside-sparing effects of enoximone.

    abstract::Thirty patients who had undergone coronary artery bypass grafting and who required vasodilator therapy for control of arterial hypertension were allocated to receive either low-dose or high-dose enoximone or placebo infusions. A closed-loop arterial pressure control system was used to assess cardiovascular stability a...

    journal_title:Cardiology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1159/000174671

    authors: Chaudhri S,Kenny GN

    更新日期:1990-01-01 00:00:00

  • When Calcium Gets Tough, the Tough Cardiologist Starts to Play ….

    abstract::Coronary calcification is a hard challenge for the interventional cardiologist, as it is associated with incomplete stent expansion and frequently stent failure. In recent years, innovative techniques, such as rotational atherectomy, have been developed to treat coronary calcification. However, these are burdened with...

    journal_title:Cardiology

    pub_type: 杂志文章

    doi:10.1159/000495177

    authors: Tassone EJ,Tripolino C,Morabito G,Grillo P,Missiroli B

    更新日期:2018-01-01 00:00:00

  • Water immersion-induced skin wrinkling is related to heart rate variability.

    abstract::Water immersion-induced skin wrinkling (WISW) is dependent on intact peripheral sympathetic function. WISW was hypothesized to reflect autonomic function in subjects without peripheral neuropathy. We prospectively studied 70 healthy subjects (aged 31 ± 8 years, 63% females) without cardiovascular risk factors or neuro...

    journal_title:Cardiology

    pub_type: 杂志文章

    doi:10.1159/000316043

    authors: Win S,Salciccioli L,Kamran H,Baweja P,Stewart M,Lazar JM

    更新日期:2010-01-01 00:00:00

  • Presence of contractile-type smooth muscle cells in the endocardium.

    abstract::A smooth muscle layer exists in the parietal endocardium. Notwithstanding previous pioneer work, little has been known on the phenotypes of these smooth muscles. In humans as in animals, smooth muscles show two distinct phenotypes, the 'synthetic' and 'contractile' states, which can be differentiated on the basis of t...

    journal_title:Cardiology

    pub_type: 杂志文章

    doi:10.1159/000177055

    authors: Suzuki T,Aikawa M,Kuro-o M,Watanabe M,Kimura K,Yazaki Y,Nagai R

    更新日期:1996-01-01 00:00:00

  • Systolic time intervals in chronic obstructive pulmonary disease.

    abstract::The systolic time intervals (STI) were used to study the left ventricular performance in 51 patients with chronic obstructive pulmonary disease (COPD), in 24 normal subjects and in 13 patients with both COPD and coronary heart disease (CHD). Our study shows that resting spine STI are abnormal in patients with COPD and...

    journal_title:Cardiology

    pub_type: 杂志文章

    doi:10.1159/000173261

    authors: Louridas G,Patakas D,Christaki R,Stavropoulos C

    更新日期:1981-01-01 00:00:00

  • A low-dose β1-blocker effectively and safely slows the heart rate in patients with acute decompensated heart failure and rapid atrial fibrillation.

    abstract:OBJECTIVE:Recently, we reported that low-dose landiolol (1.5 µg·kg(-1)·min(-1)), an ultra-short-acting β-blocker, safely decreased the heart rate (HR) in patients with acute decompensated heart failure (ADHF) and sinus tachycardia, thereby improving cardiac function. We investigated whether low-dose landiolol effective...

    journal_title:Cardiology

    pub_type: 杂志文章

    doi:10.1159/000355312

    authors: Kobayashi S,Murakami W,Myoren T,Tateishi H,Okuda S,Doi M,Nao T,Wada Y,Matsuzaki M,Yano M

    更新日期:2014-01-01 00:00:00

  • Effect of temperature and coronary flow on the metabolic and mechanical function of the isolated rat heart.

    abstract::A number of cardiac metabolic intermediates, namely, adenosine triphosphate (ATP), H+, phosphocreatine (PCr), inorganic phosphate (Pi), adenosine diphosphate (ADP), and related functions of these intermediates, Gibbs' free energy of ATP hydrolysis (delta G) and phosphorylation ratio [ATP/(ADP.Pi)], are thought to adju...

    journal_title:Cardiology

    pub_type: 杂志文章

    doi:10.1159/000175871

    authors: Blum H,Ivanics T,Zhang D,Wroblewski K,Osbakken MD

    更新日期:1993-01-01 00:00:00

  • ACE inhibitors in congestive heart failure.

    abstract::The renin-angiotensin-aldosterone system plays an important role in the development of congestive heart failure (CHF). In patients with chronic heart failure, angiotensin-converting enzyme (ACE) inhibitors, such as captopril, enalapril, and quinapril, have been shown to improve hemodynamics, reduce symptoms of fatigue...

    journal_title:Cardiology

    pub_type: 临床试验,杂志文章,随机对照试验,评审

    doi:10.1159/000174558

    authors: Riegger AJ

    更新日期:1989-01-01 00:00:00

  • Use of programmed stimulation in identifying patients at high risk for sudden cardiac death.

    abstract::Sudden cardiac death accounts for 60% of the total cardiovascular mortality in the United States. Individuals after myocardial infarction or with chronic left ventricular dysfunction are known to be at increased risk. Noninvasive studies have been applied to these populations, but the predictive accuracy of these test...

    journal_title:Cardiology

    pub_type: 杂志文章

    doi:10.1159/000174604

    authors: Hessen SE,Nydegger CC,Kutalek SP

    更新日期:1990-01-01 00:00:00

  • Abnormal left ventricular filling pattern in patients with single vessel coronary artery disease: effect of angioplasty.

    abstract::To study the effect of coronary angioplasty (PTCA) on left ventricular (LV) diastolic filling, mitral Doppler flow tracings of 15 patients with isolated stenosis of the left anterior descending coronary artery (LAD) and normal systolic LV function were recorded before PTCA as well as 24 h and 3 months after successful...

    journal_title:Cardiology

    pub_type: 杂志文章

    doi:10.1159/000175007

    authors: Ricou F,Lerch R,Meier B,Rutishauser W

    更新日期:1992-01-01 00:00:00

  • Ibopamine as a valuable adjunct and substitute for dopamine in bridging therapy before heart transplantation.

    abstract::Ibopamine is an active dopamine analogue leading to improved renal perfusion and afterload reduction in heart failure. This report describes casuistic experiences in patients with severe heart failure awaiting heart transplantation. All patients could be stabilized, intravenous catecholamines be discontinued, and diur...

    journal_title:Cardiology

    pub_type: 杂志文章

    doi:10.1159/000175786

    authors: Kleber FX,Sabin GV,Thyroff-Friesinger U,Cabell B,Glogar D

    更新日期:1992-01-01 00:00:00

  • Comparison of Quality of Life Perceived by Patients with Bioprosthetic versus Mechanical Valves after Composite Aortic Root Replacement.

    abstract:OBJECTIVE:To assess whether postoperative quality of life (QOL) for composite aortic root replacement patients differs according to whether it is based on the use of mechanical valves or bioprosthetic valves. METHODS:The study included 146 consecutive patients who underwent composite aortic root replacement at our ins...

    journal_title:Cardiology

    pub_type: 杂志文章

    doi:10.1159/000438783

    authors: Repack A,Ziganshin BA,Elefteriades JA,Mukherjee SK

    更新日期:2016-01-01 00:00:00

  • Recurrent preexcited reciprocating tachycardia, concealed ventricular preexcitation and conduction disturbances in the normal atrioventricular pathway in a newborn.

    abstract::We describe a newborn infant with concealed ventricular preexcitation in sinus rhythm on the early ECGs, and who developed recurrent episodes of preexcited reciprocating tachycardia. Manifestation of the ventricular preexcitation and initiation of the tachycardias were dependent on the presence of severe conduction di...

    journal_title:Cardiology

    pub_type: 杂志文章

    doi:10.1159/000173991

    authors: Belhassen B,Pardo J,Peled B,Blieden L,Laniado S

    更新日期:1986-01-01 00:00:00

  • Automated phonocardiographic screening for heart disease in children.

    abstract::Mass screening for heart disease in children can be accomplished by automatic analysis of phonocardiograms (PCG) obtained from five routine auscultation points. An ECG signal serves as reference. PCG signals exceeding 20% of the amplitude of the first heart sound S1 in the diastolic interval and 40% of S1 in the systo...

    journal_title:Cardiology

    pub_type: 杂志文章

    doi:10.1159/000169876

    authors: Ninova PP,Dascalov IK,Dimitrova MI

    更新日期:1978-01-01 00:00:00

  • Common form of Lyme borreliosis carditis--complete heart block with syncope: report on 3 cases.

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    pub_type: 杂志文章

    doi:10.1159/000177064

    authors: Vasiljević Z,Dmitrović R,Naumović Z,Ostojić M,Radosavljević M,Karadzić A,Prostran M,Colić M

    更新日期:1996-01-01 00:00:00

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    pub_type: 杂志文章

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    更新日期:2003-01-01 00:00:00