Abstract:
:Renal and intrarenal distribution of flow together with an index of cardiac output is measurable using a single injection of 123I-o-iodohippurate. The argument is presented that in the treatment of essential hypertension one should avoid using drugs that reduce renal blood flow, a property of chronic therapy with most beta-blockers or diuretics. Reduction of renal blood flow is a stimulus to salt retention and renin release which tend to maintain hypertension. Drugs which increase renal blood flow, thereby augmenting the renal loss of salt and decreasing renin release, tend to reduce hypertension in the long term.
journal_name
Cardiologyjournal_title
Cardiologyauthors
Britton KEdoi
10.1159/000173940subject
Has Abstractpub_date
1985-01-01 00:00:00pages
22-9eissn
0008-6312issn
1421-9751journal_volume
72 Suppl 1pub_type
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