Radioisotopic renal function studies in essential hypertension.

Abstract:

:Renal and intrarenal distribution of flow together with an index of cardiac output is measurable using a single injection of 123I-o-iodohippurate. The argument is presented that in the treatment of essential hypertension one should avoid using drugs that reduce renal blood flow, a property of chronic therapy with most beta-blockers or diuretics. Reduction of renal blood flow is a stimulus to salt retention and renin release which tend to maintain hypertension. Drugs which increase renal blood flow, thereby augmenting the renal loss of salt and decreasing renin release, tend to reduce hypertension in the long term.

journal_name

Cardiology

journal_title

Cardiology

authors

Britton KE

doi

10.1159/000173940

subject

Has Abstract

pub_date

1985-01-01 00:00:00

pages

22-9

eissn

0008-6312

issn

1421-9751

journal_volume

72 Suppl 1

pub_type

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