Abstract:
:Recently it has been demonstrated that the administration of n-acetylocysteine (NAC), in combination with streptokinase, significantly diminished oxidative stress in patients with myocardial infarction. The aim of our study was to assess the influence of NAC treatment, as adjunct therapy in an evolving myocardial infarction, on the polymorphonuclear count, superoxide anion and hydrogen peroxide levels and nitric oxide production by PMNs and authentic plasma hydroperoxide (ROOH). Treatment of patients with NAC in addition to reperfusion therapy was accompanied by a significant decrease in the number of circulating polymorphonuclear neutrophils. However, the oxygen metabolism of PMNs was not affected by NAC administration. The concentration of authentic plasma hydroperoxide was significantly reduced by the administration of NAC which suggests diminished oxidative stress during acute myocardial infarction.
journal_name
Cardiologyjournal_title
Cardiologyauthors
Sajkowska A,Wykretowicz A,Szczepanik A,Kempa M,Minczykowski A,Wysocki Hdoi
10.1159/000006878subject
Has Abstractpub_date
1999-01-01 00:00:00pages
60-5issue
1eissn
0008-6312issn
1421-9751pii
6878journal_volume
91pub_type
临床试验,杂志文章,随机对照试验相关文献
CARDIOLOGY文献大全abstract::It has been shown that endothelial cell adhesion molecules play an important role in the development of coronary atherosclerosis and inflammatory disease. We sought to test whether soluble vascular cell adhesion molecule-1 (VCAM-1), intercellular adhesion molecule-1 (ICAM-1) and E-selectin are increased in patients wi...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000006995
更新日期:2000-01-01 00:00:00
abstract:OBJECTIVES:To evaluate the prognostic significance of early ultra-short-term heart rate variability (HRV) measurement in patients admitted for ST-elevation myocardial infarction (STEMI). METHODS:HRV was calculated retrospectively from the standard admission and discharge 10-second ECG of 196 consecutive patients with ...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000235568
更新日期:2009-01-01 00:00:00
abstract::A bicuspid aortic valve (BAV) is one of the most common congenital heart anomalies. Although each annuloaortic ectasia (AAE) and malformation of the left coronary artery has been described as a complication of BAV, no case associated with both abnormalities has been reported previously. We present here a very rare cas...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000176329
更新日期:1994-01-01 00:00:00
abstract::In order to compare the acute hemodynamic effects of digoxin (0.01 mg/kg) and enoximone (1 mg/kg), a phosphodiesterase inhibitor inotropic agent, in severe chronic congestive heart failure, 8 patients (male, mean age 56.7 years, sinus rhythm) were investigated with a randomized cross-over study. Peak effect of enoximo...
journal_title:Cardiology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1159/000176702
更新日期:1994-01-01 00:00:00
abstract::Fractional flow reserve (FFR) may not be immune from hemodynamic perturbations caused by both vessel and lesion related factors. The aim of this study was to investigate the impact of plaque- and vessel wall-related features of vulnerability on the hemodynamic effect of intermediate coronary stenoses. Methods and Resu...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000508885
更新日期:2021-01-01 00:00:00
abstract::Low cardiac output in acute heart failure can result in a functional impairment of organs, when tissue hypoxia occurs and cardiogenic shock develops. To restore cardiac output, various forms of therapy can be considered. Fluid replacement is sometimes beneficial in acute situations where oedema can reduce effective pl...
journal_title:Cardiology
pub_type: 临床试验,杂志文章
doi:10.1159/000174667
更新日期:1990-01-01 00:00:00
abstract::The effects of arterial compliance on stenotic hemodynamics were examined in an in vitro arterial preparation. Carotid arteries, obtained from anesthetized mongrel dogs (11.3-15.4 kg), were attached to a perfusion apparatus consisting of a constant pressure reservoir and a fixed distal resistance. To create an intralu...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000173478
更新日期:1982-01-01 00:00:00
abstract:INTRODUCTION:COVID-19 is a rapidly growing infectious disease that represents an immediate threat for the health of millions of people around the world, both in direct and indirect ways. CASE PRESENTATION:In the present report we describe the development of stress cardiomyopathy in a patient who was overwhelmingly str...
journal_title:Cardiology
pub_type:
doi:10.1159/000511450
更新日期:2020-01-01 00:00:00
abstract::This study was undertaken to assess ventricular volumes and function by radionuclide angiography during asynchronous ventricular pacing in a group of 22 patients who needed an artificial pacemaker. 14 had ischaemic heart disease and 8 had primary disturbances of conduction of the impulse-forming system. The transition...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000173685
更新日期:1984-01-01 00:00:00
abstract::Abnormal systolic anterior (SAM) motion of the mitral valve without asymmetric hypertrophy of the interventricular septum was observed in 16 patients (group 1). 5 of the 16 patients had no other evidence of heart disease and the remaining 11 had a variety of cardiac disorders. Left ventricular dimensions, septal and p...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000170860
更新日期:1980-01-01 00:00:00
abstract:BACKGROUND:Mitral valve prolapse (MVP) is a common entity in female population. Although this is a minor disease, it may cause annoying symptoms that impair quality of life (QOL), and no established therapy for this problem. The aim of this study isto examine whether programmed exercise training by treadmill in female ...
journal_title:Cardiology
pub_type: 临床试验,杂志文章
doi:10.1159/000096952
更新日期:2007-01-01 00:00:00
abstract:OBJECTIVE:The systematic pro-inflammatory responses after percutaneous coronary intervention with drug-eluting stents (DES) remain poorly defined. Therefore, we compared the systematic pro-inflammatory state of circulating mononuclear cells (MNCs) between DES and bare metal stent (BMS) implantation. METHODS:Patients w...
journal_title:Cardiology
pub_type: 杂志文章,随机对照试验
doi:10.1159/000358508
更新日期:2014-01-01 00:00:00
abstract::Earlier studies have shown that spinal cord stimulation (SCS) has antianginal and anti-ischemic effects in severe coronary artery disease. In the present study, 14 patients were subjected to right-sided atrial catheterization and atrial pacing. The patients were paced to angina during a control session and during spin...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000006783
更新日期:1998-03-01 00:00:00
abstract::Acute renal infarction due to emboli represents a very rare but significant threat for kidney loss, and the clinical presentation is challenging. The differential diagnosis of massive renal thrombi includes all other causes of abdominal pain, and they can be easily misdiagnosed as renal colic due to nephrolithiasis. A...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000322510
更新日期:2010-01-01 00:00:00
abstract:OBJECTIVE:To compare all-cause mortality in JUPITER with other statin trials at 21 months of follow-up. BACKGROUND:Outcome advantages including all-cause mortality reduction yielded from the JUPITER trial support aggressive use of rosuvastatin and, perhaps by extension, other statins for primary prevention. Despite en...
journal_title:Cardiology
pub_type: 社论
doi:10.1159/000330507
更新日期:2011-01-01 00:00:00
abstract::This prospective investigation was conducted in an attempt to identify noninvasive predictors of mortality for patients with Chagas' heart disease through a multivariate stepwise logistic regression study. Fifty-six patients with a positive complement fixation test for Chagas' disease were followed up at the Cardiomyo...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000176409
更新日期:1994-01-01 00:00:00
abstract:OBJECTIVES:The aim of this study is to retrospectively analyze risk factors, diagnosis and management of gastrointestinal (GI) complications following cardiac operations. METHODS:Patients who developed GI complications after a cardiac operation were studied. Anesthesia protocols, techniques of cardiac surgery, potenti...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000119696
更新日期:2008-01-01 00:00:00
abstract::We describe the 2- and 5-year prognoses following coronary artery bypass grafting (CABG) in relation to smoking habits among consecutive patients being operated on in western Sweden during a 3-year period. Among the 2,121 patients, 10.2% admitted smoking at coronary angiography as compared with 7.5% 2 years after CABG...
journal_title:Cardiology
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1159/000177397
更新日期:1997-11-01 00:00:00
abstract:OBJECTIVE:Recent studies have shown that high-sensitivity C-reactive protein (hs-CRP) measured before cardioversion (CV) plays a significant role in predicting atrial fibrillation (AF) relapse. The time course of changes in hs-CRP after successful electrical CV remains controversial. The aim of the present study was to...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000327998
更新日期:2011-01-01 00:00:00
abstract::Ventricular late potentials are obtained by signal-averaged surface electrocardiography. Late potentials in normal subjects may be influenced by physiological elements such as gender, height and body mass index. Considering that growth hormone (GH) hypersecretion is able to markedly alter different anthropometric vari...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000176852
更新日期:1995-01-01 00:00:00
abstract::A 50-year-old man with intermittent ventricular parasystolic bigeminy is reported in whom the parasystolic focus was protected from late intervening sinus impulses. This is the first report to suggest the presence of protection due to interference in parasystolic bigeminy. The findings in this case suggest that when a...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000174583
更新日期:1990-01-01 00:00:00
abstract::To determine the success rate and the safety of percutaneous transluminal coronary angioplasty in patients with unstable angina pectoris (group 1) versus stable angina (group 2), we studied 299 consecutive patients who underwent coronary angioplasty of 373 consecutive lesions. Of these patients, 149 had unstable angin...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000175811
更新日期:1992-01-01 00:00:00
abstract::Four biochemical markers, creatine kinase (CK)-MB isoenzyme, myoglobin, myosin light chains and troponin I, were studied in 1,338 patients presenting to the emergency department with chest pain suggestive of coronary artery disease (CAD). One hundred and eighty-seven patients had an acute myocardial infarction (MI). A...
journal_title:Cardiology
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1159/000007033
更新日期:2000-01-01 00:00:00
abstract::We assessed the left ventricle function in 24 patients with severe (forced expiratory volume in 1 sec less than 50% of predicted) chronic obstructive pulmonary disease (COPD) and in 21 normal people. We measured the left ventricular systolic time intervals (STI) and echocardiographic left ventricular diameters, volume...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000173231
更新日期:1981-01-01 00:00:00
abstract:OBJECTIVES:Mutations in genes encoding desmosomal proteins have been linked to arrhythmogenic right ventricular cardiomyopathy/dysplasia (ARVC/D). We hypothesized that a Scandinavian ARVC/D population would have a different spectrum of plakophilin-2 (PKP2) mutations and that some of the reported missense mutations may ...
journal_title:Cardiology
pub_type: 评论,杂志文章
doi:10.1159/000263456
更新日期:2010-01-01 00:00:00
abstract::The primary aim of the management of hypertension should be to prevent coronary heart disease. Antihypertensive treatment should have a beneficial effect on the risk factors associated with coronary heart disease, particularly hypertension, dyslipidemia, hyperinsulinemia, and/or glucose intolerance. Other important ri...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000176764
更新日期:1994-01-01 00:00:00
abstract:OBJECTIVES:Increased homocysteine (HCY) levels are associated with an increased risk of cardiovascular disease. Plasma HCY is increased in chronic heart failure (CHF) patients, and previous studies suggest that hyperhomocysteinemia causes adverse cardiac remodeling and affects pump function. We aimed to evaluate the HC...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000320106
更新日期:2010-01-01 00:00:00
abstract::Antihypertensive therapy has been thought to be a life-long treatment. Nevertheless, antihypertensive medication may be discontinued in a substantial proportion of hypertensive patients at least for some time. The current study focused on predictors for the development of elevated blood pressure levels after discontin...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000177343
更新日期:1997-05-01 00:00:00
abstract::A 65-year-old female patient suffering from hypertension and myxedema due to chronic thyroiditis developed anginal attacks under trichlormethiazide therapy. The ECG revealed a SA block with reciprocal beats and aberrant ventricular conduction in a form of bigeminy. Upon substitution of desiccated thyroid for the antih...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000169716
更新日期:1975-01-01 00:00:00
abstract:OBJECTIVES:The present study aimed to evaluate the hypertension status of community residents, analyze environmental and epigenetic factors, and propose prevention measures for hypertension. METHODS:In our study, different methylation levels were distinguished utilizing melting temperature (Tm) values in both the case...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000458520
更新日期:2017-01-01 00:00:00