Abstract:
:Mass screening for heart disease in children can be accomplished by automatic analysis of phonocardiograms (PCG) obtained from five routine auscultation points. An ECG signal serves as reference. PCG signals exceeding 20% of the amplitude of the first heart sound S1 in the diastolic interval and 40% of S1 in the systolic interval are considered as abnormal. Signals in the systolic interval with an amplitude between 20 and 40% of S1 are classified as normal if their duration is less than two-thirds of the interval from the first to second heart sound. Thus, the method takes into account innocent murmurs and classifies them as normal. The splitting of the second sound is detected by monitoring its duration at a level of 20% of S1. This method was tested on 2,583 children aged from 3 to 14 years and on 345 children with proven heart disease. The results obtained showed a sensitivity of 96.5% and a specificity of 92.4%.
journal_name
Cardiologyjournal_title
Cardiologyauthors
Ninova PP,Dascalov IK,Dimitrova MIdoi
10.1159/000169876subject
Has Abstractpub_date
1978-01-01 00:00:00pages
5-13issue
1eissn
0008-6312issn
1421-9751journal_volume
63pub_type
杂志文章相关文献
CARDIOLOGY文献大全abstract::The renin-angiotensin-aldosterone system plays an important role in the development of congestive heart failure (CHF). In patients with chronic heart failure, angiotensin-converting enzyme (ACE) inhibitors, such as captopril, enalapril, and quinapril, have been shown to improve hemodynamics, reduce symptoms of fatigue...
journal_title:Cardiology
pub_type: 临床试验,杂志文章,随机对照试验,评审
doi:10.1159/000174558
更新日期:1989-01-01 00:00:00
abstract::We investigated the effect of mannan-binding lectin (MBL) deficiency on the susceptibility to bypass graft occlusion in 62 patients with coronary heart disease. MBL deficiency appeared to be associated with occlusion (p = 0.0099). A high level of anti-cardiolipin IgG as well as the number of venous bypass grafts were ...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000066313
更新日期:2002-01-01 00:00:00
abstract::The spectrum of patients operated on without preoperative catheterization and angiography, the accuracy of echocardiographic diagnosis and its impact on the results of surgical treatment were prospectively assessed in 2,788 children consecutively operated for congenital heart defects (CHD) between 1986 and 1992. The o...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000176928
更新日期:1995-01-01 00:00:00
abstract:BACKGROUND:The purpose of the present study was to examine physician's attitudes and practices toward the use of different lipid-lowering management strategies in patients at increased risk for coronary heart disease (CHD). AIMS/METHODS:An internet-based questionnaire was completed by 78 general internists and family ...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000099066
更新日期:2007-01-01 00:00:00
abstract::A sixteen-year-old male presented with symptoms and investigations suggestive of acute myocardial infarction. The patient had suffered from a varicella zoster infection 5 days prior to presentation. Varicella myocarditis was suspected and diagnosed following treatment and positive varicella serology. This case highlig...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000106682
更新日期:2008-01-01 00:00:00
abstract::We describe a newborn infant with concealed ventricular preexcitation in sinus rhythm on the early ECGs, and who developed recurrent episodes of preexcited reciprocating tachycardia. Manifestation of the ventricular preexcitation and initiation of the tachycardias were dependent on the presence of severe conduction di...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000173991
更新日期:1986-01-01 00:00:00
abstract::Ventricular late potentials are obtained by signal-averaged surface electrocardiography. Late potentials in normal subjects may be influenced by physiological elements such as gender, height and body mass index. Considering that growth hormone (GH) hypersecretion is able to markedly alter different anthropometric vari...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000176852
更新日期:1995-01-01 00:00:00
abstract:BACKGROUND:Left-ventricular pseudohypertrophy reflecting left-ventricular compression was reported in a selected group of patients with cardiac tamponade. HYPOTHESIS:Criteria for the presence of pseudohypertrophy can be established to guide its use as a sign of left-ventricular compression in patients with cardiac tam...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000047319
更新日期:2000-01-01 00:00:00
abstract::Since the reported incidence of pericardial effusion following thrombolysis is highly variable, we have evaluated 80 consecutive patients with first acute myocardial infarction treated with streptokinase. Two-dimensional echocardiographic studies were performed on days 1, 2, 3, and 7, at 3 and 6 weeks, and 3, 6, and 1...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000177417
更新日期:1997-11-01 00:00:00
abstract::Transcatheter electrical shock ablation of a concealed posteroseptal accessory pathway was performed on a 57-year-old man with drug-refractory paroxysmal supraventricular tachycardia. A single 300-joules shock delivered at the ostium of the coronary sinus abolished conduction in the accessory pathway and resulted in l...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000174387
更新日期:1988-01-01 00:00:00
abstract:BACKGROUND:Previous studies have suggested that a lower lymphocyte ratio (Ly%) in the white blood cell (WBC) differential count is related to worse outcomes in patients with acute heart failure (AHF) and other cardiovascular disorders. METHODS:In the Pre-RELAX-AHF study, 234 patients with AHF, systolic blood pressure ...
journal_title:Cardiology
pub_type: 杂志文章,随机对照试验
doi:10.1159/000321416
更新日期:2010-01-01 00:00:00
abstract::Ventricular late potentials are obtained by signal averaging of surface electrocardiograms. Late potentials have been reported to be affected by body size or left ventricular mass. However, the effect of subadipose tissue, which is known to influence QRS amplitudes of surface ECG, on the variables of late potentials h...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000175854
更新日期:1993-01-01 00:00:00
abstract:OBJECTIVES:Endothelin-1 (ET-1) induces cardiac hypertrophy, whereas adiponectin may elicit protective effects in the vasculature and myocardium. We therefore evaluated the relationship between plasma ET-1 and adiponectin levels in heart failure (HF) patients, and the association between adiponectin expression and ET-1-...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000328780
更新日期:2011-01-01 00:00:00
abstract::Physical training causes an increase of aerobic capacity in normal and cardiac patients. The influences of training plus placebo and training plus verapamil have been studied in a double-blind randomized trial on 40 patients recovering from actue myocardial infarction. The two groups were comparable as to clinical cha...
journal_title:Cardiology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1159/000170635
更新日期:1979-01-01 00:00:00
abstract::Single photon emission computed tomographic (SPECT) imaging with thallium-201 was evaluated in 492 consecutive, unselected patients to ascertain the patterns of use and additive value to the exercise electrocardiogram in the diagnosis of myocardial ischemia in a community hospital setting. Myocardial perfusion images ...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000177076
更新日期:1996-03-01 00:00:00
abstract::Carvedilol is a multiple-action cardiovascular agent that is a nonselective beta-adrenoceptor antagonist and a vasodilator. beta-Adrenoceptor antagonists reduce myocardial work, secondary to reductions in heart rate and contractility, both in animals and in humans. For these reasons, carvedilol may improve survival of...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000175930
更新日期:1993-01-01 00:00:00
abstract:OBJECTIVES:Studies evaluating the long-term outcome of adults with ventricular septal defect (VSD) are important to inform patients about prognosis. This study investigated the long-term outcome of patients with perimembranous VSD (pmVSD) followed in the Belgian Registry on Adult Congenital Heart Disease. METHODS:All ...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000448513
更新日期:2017-01-01 00:00:00
abstract::In a 79-year-old female with shortness of breath, catheterization via the femoral vein encountered difficulty entering the right heart; venography revealed anomalous drainage of the inferior vena cava via a dilated azygos vein permitting subsequent catheterization. Similar difficulties during catheterization merit con...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000176884
更新日期:1995-01-01 00:00:00
abstract::The National Exercise and Heart Disease Project (NEHDP) was funded by the Rehabilitation Services Administration (RSA) of the Department of Health, Education and Welfare, to determine the effects of regular physical activity on the rehabilitation, morbidity and mortality of patients with healed myocardial infarctions....
journal_title:Cardiology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1159/000169916
更新日期:1978-01-01 00:00:00
abstract::Helicobacter pylori infects over 50% of the worldwide population. For eradication, European, Canadian, and American guidelines recommend a regimen consisting of a proton pump inhibitor, clarithromycin, and metronidazole or amoxicillin dosed twice daily for at least 7 days. When this treatment strategy fails, a complex...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000110489
更新日期:2008-01-01 00:00:00
abstract::Review of a longitudinal study of the effects of 40 mg of propranolol orally in 14 patients with coronary heart disease demonstrated a minor but not statistically significant change in the relationship of percentage of maximal oxygen uptake to percentage of maximal heart rate. In a cross-sectional comparison of severa...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000170794
更新日期:1980-01-01 00:00:00
abstract::We investigated in 306 patients, mean age 57 +/- 10 years, with diabetes mellitus (202 patients) or hypertension (179 patients) whether microalbuminuria was a significant independent risk factor for the development of new stroke or new myocardial infarction (MI) or death. At 39-month follow-up, new stroke or new MI or...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000105327
更新日期:2008-01-01 00:00:00
abstract::Angina pectoris due to coronary artery disease is a common manifestation of myocardial ischemia. Reduction of oxygen demand (beta-blockers) and relief of coronary vasoconstriction (calcium blocker or nitrate) are additive approaches to controlling ischemia. Risk factor reduction may improve coronary vascular physiolog...
journal_title:Cardiology
pub_type: 杂志文章,评审
doi:10.1159/000177503
更新日期:1997-01-01 00:00:00
abstract:OBJECTIVES:We aimed to measure changes in the levels of several miRNAs during open-heart surgery and to investigate the relationship between these changes and cardiac biomarkers. METHODS:Creatine kinase-muscle band (CK-MB), cardiac troponin (cTnI) and miRNA (miR-1/21/208a/499) levels were measured during open-heart su...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000371792
更新日期:2015-01-01 00:00:00
abstract:OBJECTIVE:To investigate the effect of nicotine on cardiomyocyte apoptosis in vitro and explore the potential mechanisms involved. METHODS:The MTT assay was used to detect the viability of cultured cardiomyocytes exposed to different concentrations of nicotine (0.1-100 microM). Laser confocal microscopy, TUNEL assay a...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000301278
更新日期:2010-01-01 00:00:00
abstract:BACKGROUND:Pulmonary embolism (PE) is a life-threatening event with a broad presentation spectrum ranging from asymptomatic cases to sudden cardiac arrest. It is unclear if right atrial emboli cause PE in patients with atrial fibrillation (AF) or if mild PE itself increases right cardiac pressure provoking AF. OBJECTI...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000444440
更新日期:2016-01-01 00:00:00
abstract:OBJECTIVES:The present study aimed to evaluate the hypertension status of community residents, analyze environmental and epigenetic factors, and propose prevention measures for hypertension. METHODS:In our study, different methylation levels were distinguished utilizing melting temperature (Tm) values in both the case...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000458520
更新日期:2017-01-01 00:00:00
abstract:PURPOSE:Electrocardiographic (ECG) ST segment elevation lasting 2 or more weeks following Q wave myocardial infarction has been associated with 'ventricular aneurysm' and absence of tissue viability. Regional systolic dysfunction may reflect either viable myocardium or scar. Positron emission-tomographic (PET) imaging ...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000072386
更新日期:2003-01-01 00:00:00
abstract::Bromocriptine-induced coronary spasm (BICS) causing myocardial infarction has been reported. Association between BICS and Takotsubo syndrome (TS) has not been described. We report on a 37-year-old woman presenting with a clinical picture of acute coronary syndrome 1 day after initiation of treatment with bromocriptine...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000329349
更新日期:2011-01-01 00:00:00
abstract::Fifty percent of patients with dilated cardiomyopathy die within 5 years of diagnosis. Syncope is known to be a predictor of poor outcome in patients with advanced heart failure. To assess the risk of patients with dilated cardiomyopathy with a history of syncope during standard medical treatment we compared this grou...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000177083
更新日期:1996-05-01 00:00:00