Nicotine promotes cardiomyocyte apoptosis via oxidative stress and altered apoptosis-related gene expression.

abstract：BACKGROUND:The pathogenesis of chronic thromboembolic pulmonary hypertension (CTEPH) is largely unknown. Proteomics offers an approach to overview the molecular activities and signal transduction pathways involved in specific disease processes. OBJECTIVES:In this study, the expression of proteins in endarterectomized ...

journal_title：Cardiology

authors： Xi Q,Liu Z,Song Y,Gan H,Huang Z,Luo Q,Zhao Z

更新日期：2020-01-01 00:00:00

abstract：:Fractional flow reserve (FFR) may not be immune from hemodynamic perturbations caused by both vessel and lesion related factors. The aim of this study was to investigate the impact of plaque- and vessel wall-related features of vulnerability on the hemodynamic effect of intermediate coronary stenoses. Methods and Resu...

journal_title：Cardiology

authors： Sezer M,Aslanger E,Cakir O,Atici A,Sezer I,Ozcan A,Umman B,Bugra Z,Umman S

更新日期：2021-01-01 00:00:00

abstract：:Clopidogrel, in combination with acetylsalicylic acid, has become a mainstay of the pharmacological therapy for patients with acute coronary syndromes, especially in those undergoing percutaneous coronary interventions (PCI). While a series of studies has shown that pre-treatment with a loading dose of clopidogrel 300...

journal_title：Cardiology

authors： Zeymer U,Arntz HR,Darius H,Huber K,Senges J

更新日期：2007-01-01 00:00:00

abstract：:Apical segmental dysfunction is an unusual finding in hypertrophic cardiomyopathy (HCM). It is characterized by a poor clinical course and a high incidence of malignant ventricular tachyarrhythmias. Long-term prognosis of patients with HCM and apical segmental dysfunction is still unclear. We report 2 cases of apical ...

journal_title：Cardiology

authors： Ko YL,Lin JL,Lei MH,Chen JJ,Tsou SS,Kuan P,Lien WP

更新日期：1995-01-01 00:00:00

abstract：:Helicobacter pylori infects over 50% of the worldwide population. For eradication, European, Canadian, and American guidelines recommend a regimen consisting of a proton pump inhibitor, clarithromycin, and metronidazole or amoxicillin dosed twice daily for at least 7 days. When this treatment strategy fails, a complex...

journal_title：Cardiology

authors： Page RL 2nd,Ferguson D,Cantu M

更新日期：2008-01-01 00:00:00

abstract：:Electrocardiographic responses of body-builders and control subjects obtained during the performance of static and dynamic Valsalva maneuvers were studied to determine the causative stimulus for wandering pacemaker activity. The incidence of shifting or wandering pacemaker was nearly double in body-builders, suggestin...

journal_title：Cardiology

authors： Borgia JF,Nizet PM,Gliner JA,Horvath SM

更新日期：1982-01-01 00:00:00

abstract：:Three-dimensional imaging of cardiac structures could enhance the functional understanding and the interpretation of pathologies. Limited processing capabilities, relocation problems and inadequate two-dimensional image quality have previously limited its applicability. Recently, an integrated echocardiographic comput...

journal_title：Cardiology

authors： Binder T,Globits S,Zangeneh M,Gabriel H,Röthy W,Glogar D,Maurer G,Baumgartner H

更新日期：1996-07-01 00:00:00

abstract：:The 6-min walk test (6MWT) is a simple and inexpensive exercise test to evaluate physical functional capacity that is widely used in heart failure (HF) patients. With the 6MWT, a distance <350 m is associated with increased mortality in patients with HF, and change in walking distance >50 m is considered clinically re...

journal_title：Cardiology

authors： Sgorbini L,Rossetti A,Galati A

更新日期：2017-01-01 00:00:00

abstract：:Over the last 30 years, several epidemiological and prospective studies have identified a number of risk factors for the development of cardiovascular disease. Lipid abnormalities are central among these risk factors, and their correction has been a major target for the medical community. The 3-hydroxy-3-methyl glutar...

journal_title：Cardiology

authors： Bruckert E

更新日期：2002-01-01 00:00:00

abstract：:The acute effects of therapeutic doses of intravenous tolbutamide and glibornuride on the systolic time intervals (QS2c, LVETc, PEPc and PEP/LVET) were examined in 5 healthy volunteers. Blood sugar was maintained constant throughout the study. No significant changes of these intervals as well as of heart rate and bloo...

journal_title：Cardiology

authors： Dubach UC,Burckhardt D,Raeder EA,Forgo I,Amrein R,Bückert A

更新日期：1979-01-01 00:00:00

abstract：OBJECTIVES:To explore the relation between the baseline aortic valve gradient (AVG) as a continuous variable and clinical outcomes following transcatheter aortic valve implantation (TAVI) in general and specifically in patients with high-gradient aortic stenosis (AS). METHODS:We reviewed 317 consecutive patients who u...

journal_title：Cardiology

authors： Witberg G,Barsheshet A,Assali A,Vaknin-Assa H,Shaul AA,Orvin K,Vaturi M,Schwartzenberg S,Shapira Y,Sagie A,Kornowski R

更新日期：2016-01-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to assess the recovery of regional myocardial function of the left-ventricular septal wall and the septal site of the mitral valve (MV) annulus by tissue Doppler imaging (TDI). METHODS:In 63 (32 diabetic and 31 control) patients having off-pump coronary artery bypass grafting (OPCA...

journal_title：Cardiology

authors： Barisin A,Sonicki Z,Vincelj J,Sutlic Z,Barisin S

更新日期：2015-01-01 00:00:00

abstract：:This report describes the effect of age and gender on the results of balloon angioplasty using current technique and indications. A consecutive group of 2,067 patients who underwent angioplasty at a single institution after 1990 is described. Angioplastic success was 92.2% and similar among men and women and the vario...

journal_title：Cardiology

authors： Rozenman Y,Gilon D,Zelingher J,Sapoznikov D,Lotan C,Mosseri M,Weiss AT,Hasin Y,Gotsman MS

更新日期：1996-09-01 00:00:00

abstract：AIM:The aim of this study was to determine whether on-line vectorcardiography (VCG) gives independent prognostic information, regarding death, myocardial infarction (MI), and revascularization in patients with unstable coronary artery disease, i.e. unstable angina or non-Q-wave MI. METHODS AND RESULTS:One hundred and ...

journal_title：Cardiology

authors： Lundin P,Jensen J,Lindahl B,Wallentin L,Eriksson SV

更新日期：2000-01-01 00:00:00

abstract：OBJECTIVE:Bisoprolol, carvedilol and nebivolol have been shown to be effective in the treatment of heart failure. However, the beta-blocking effects of these drugs have never been compared directly. METHODS:Therefore, we performed a randomized, double-blind, placebo-controlled, cross-over trial in 16 healthy males. Su...

journal_title：Cardiology

authors： Stoschitzky K,Stoschitzky G,Brussee H,Bonelli C,Dobnig H

更新日期：2006-01-01 00:00:00

abstract：OBJECTIVE:The PRevention of cArdiac Dysfunction during Adjuvant breast cancer therapy (PRADA) study is a randomized, placebo-controlled, double-blind trial to determine whether angiotensin receptor blockers (ARB), or beta-blockers or their combination may prevent the development of left ventricular (LV) dysfunction in ...

journal_title：Cardiology

authors： Heck SL,Gulati G,Ree AH,Schulz-Menger J,Gravdehaug B,Røsjø H,Steine K,Bratland A,Hoffmann P,Geisler J,Omland T

更新日期：2012-01-01 00:00:00

abstract：:During a 21-month period, the prognosis in all patients admitted to a hospital ward from the emergency room with suspected acute myocardial infarction (AMI) was prospectively recorded and related to the time between onset of symptoms and arrival in hospital. They were classified as early arrivers (less than or equal t...

journal_title：Cardiology

authors： Karlson BW,Herlitz J,Liljekvist JA,Pettersson P,Hallgren P,Strömbom U,Hjalmarson A

更新日期：1991-01-01 00:00:00

abstract：OBJECTIVES:Despite recent advances in cardiovascular surgery, hyperbilirubinemia after heart valve surgery occurs often and the mechanism is not well clarified. We evaluated the incidence and nature of postoperative hyperbilirubinemia in heart valve surgery patients to analyze its risk factors and to identify its clini...

journal_title：Cardiology

authors： Nishi H,Sakaguchi T,Miyagawa S,Yoshikawa Y,Fukushima S,Saito S,Ueno T,Kuratani T,Sawa Y

更新日期：2012-01-01 00:00:00

abstract：OBJECTIVE:Risk factors like hypertension, diabetes mellitus, dyslipidemia and smoking contribute to the pathogenesis of atherothrombosis. We investigated whether the multiplicity of risk factors for atherothrombosis is associated with leukocyte activation. METHODS:We examined the availability of CD11b/CD18 antigen on ...

journal_title：Cardiology

authors： Berliner S,Rogowski O,Rotstein R,Fusman R,Shapira I,Bornstein NM,Prochorov V,Roth A,Keren G,Eldor A,Zeltser D

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND:Fibrosis in atrial myocardium is a common phenomenon for patients with atrial fibrillation (AF). Remodeling of connexins was found accompanying with AF. The aim of the study is to investigate whether it is by causing the remodeling of connexin 43 (Cx43) that the fibrosis of atrial muscle plays an important r...

journal_title：Cardiology

authors： Luo MH,Li YS,Yang KP

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:Angiotensin II (Ang II) plays an important role in cardiovascular disease. It also leads to the activation of coagulation. The coagulation protease thrombin induces cellular responses by activating protease-activated receptor 1 (PAR-1). We investigated whether PAR-1 contributes to Ang II-induced cardiovascul...

journal_title：Cardiology

authors： Antoniak S,Cardenas JC,Buczek LJ,Church FC,Mackman N,Pawlinski R

更新日期：2017-01-01 00:00:00

abstract：:Bromocriptine-induced coronary spasm (BICS) causing myocardial infarction has been reported. Association between BICS and Takotsubo syndrome (TS) has not been described. We report on a 37-year-old woman presenting with a clinical picture of acute coronary syndrome 1 day after initiation of treatment with bromocriptine...

journal_title：Cardiology

authors： Y-Hassan S,Jernberg T

更新日期：2011-01-01 00:00:00

abstract：:We investigated the incidence and determinants of early and late repeat hospitalization for cardiac causes in 378 patients following myocardial revascularization [199 coronary balloon angioplasty (PTCA), 179 coronary bypass surgery (CABG)] in a single cardiovascular center and followed for a median period of 13 years....

journal_title：Cardiology

authors： Halon DA,Rennert HS,Flugelman MY,Jaffe R,Lewis BS

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:Several lines of evidence support the clinical use of trimetazidine as an adjunctive therapy in cardioischemic patients. Therefore, we assessed here the efficacy and safety of adjunctive trimetazidine therapy in acute myocardial infarction (MI) patients by a systematic review and meta-analysis of the current...

journal_title：Cardiology

authors： Li Y,Wang D,Hu C,Zhang P,Zhang D,Qin S

更新日期：2016-01-01 00:00:00

abstract：OBJECTIVE:Recently, we reported that low-dose landiolol (1.5 µg·kg(-1)·min(-1)), an ultra-short-acting β-blocker, safely decreased the heart rate (HR) in patients with acute decompensated heart failure (ADHF) and sinus tachycardia, thereby improving cardiac function. We investigated whether low-dose landiolol effective...

journal_title：Cardiology

authors： Kobayashi S,Murakami W,Myoren T,Tateishi H,Okuda S,Doi M,Nao T,Wada Y,Matsuzaki M,Yano M

更新日期：2014-01-01 00:00:00

abstract：:We studied the relation between the plasma concentration of brain natriuretic peptide (BNP) and echocardiographic findings to determine the sensitivity of BNP as an indicator of left-ventricular dysfunction in elderly patients with various cardiovascular diseases. The plasma concentration of BNP was positively correla...

journal_title：Cardiology

authors： Yamada Y,Goto J,Yokota M

更新日期：1997-09-01 00:00:00

abstract：OBJECTIVES:Endothelin-1 (ET-1) induces cardiac hypertrophy, whereas adiponectin may elicit protective effects in the vasculature and myocardium. We therefore evaluated the relationship between plasma ET-1 and adiponectin levels in heart failure (HF) patients, and the association between adiponectin expression and ET-1-...

journal_title：Cardiology

authors： Yin WH,Chen YH,Wei J,Jen HL,Huang WP,Young MS,Chen DC,Liu PL

更新日期：2011-01-01 00:00:00

abstract：:In order to compare the acute hemodynamic effects of digoxin (0.01 mg/kg) and enoximone (1 mg/kg), a phosphodiesterase inhibitor inotropic agent, in severe chronic congestive heart failure, 8 patients (male, mean age 56.7 years, sinus rhythm) were investigated with a randomized cross-over study. Peak effect of enoximo...

journal_title：Cardiology

authors： Casella G,Cantelli I,Pavesi PC,Barbato G,Bracchetti D

更新日期：1994-01-01 00:00:00

abstract：OBJECTIVES:The aim of this study is to retrospectively analyze risk factors, diagnosis and management of gastrointestinal (GI) complications following cardiac operations. METHODS:Patients who developed GI complications after a cardiac operation were studied. Anesthesia protocols, techniques of cardiac surgery, potenti...

journal_title：Cardiology

authors： Vassiliou I,Papadakis E,Arkadopoulos N,Theodoraki K,Marinis A,Theodosopoulos T,Palatianos G,Smyrniotis V

更新日期：2008-01-01 00:00:00

abstract：:Patients with acute or chronic heart disease may have limited exercise capacity if they have reduced left ventricular function. Indexes of reduced left ventricular function during exercise are a predictor of subsequent survival although left ventricular ejection fraction is a poor predictor of physical endurance. We e...

journal_title：Cardiology

authors： Søgaard P,Gøtzsche CO,Ravkilde J,Nørgaard A,Thygesen K

更新日期：1994-01-01 00:00:00