Apical segmental dysfunction in hypertrophic cardiomyopathy: progression into end-stage heart failure with sudden cardiac death.

Abstract:

:Apical segmental dysfunction is an unusual finding in hypertrophic cardiomyopathy (HCM). It is characterized by a poor clinical course and a high incidence of malignant ventricular tachyarrhythmias. Long-term prognosis of patients with HCM and apical segmental dysfunction is still unclear. We report 2 cases of apical segmental dysfunction in HCM in whom progressive apical dilatation and congestive heart failure developed. Both patients died suddenly, and intractable ventricular tachyarrhythmias were documented in 1 case during resuscitation. This report provides further evidence that apical segmental dysfunction might predict a subgroup of patients with HCM who are likely to develop end-stage heart failure and are at high risk of sudden cardiac death.

journal_name

Cardiology

journal_title

Cardiology

authors

Ko YL,Lin JL,Lei MH,Chen JJ,Tsou SS,Kuan P,Lien WP

doi

10.1159/000176917

subject

Has Abstract

pub_date

1995-01-01 00:00:00

pages

436-40

issue

5

eissn

0008-6312

issn

1421-9751

journal_volume

86

pub_type

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