New advances in lipid-modifying therapies for reducing cardiovascular risk.

abstract：OBJECTIVE:To investigate the effect of nicotine on cardiomyocyte apoptosis in vitro and explore the potential mechanisms involved. METHODS:The MTT assay was used to detect the viability of cultured cardiomyocytes exposed to different concentrations of nicotine (0.1-100 microM). Laser confocal microscopy, TUNEL assay a...

journal_title：Cardiology

authors： Zhou X,Sheng Y,Yang R,Kong X

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The value of glycosylated hemoglobin (HbA1c) as a surrogate marker for the prevention of cardiovascular outcomes on antidiabetic drugs is debated. The 2008 FDA guidance led to multiple large clinical trials to evaluate the effect of new antidiabetic drugs versus placebo on major adverse cardia...

journal_title：Cardiology

authors： Ambrosi P,Daumas A,Villani P,Giorgi R

更新日期：2020-01-01 00:00:00

abstract：CONTEXT:Much emphasis has been placed on a ticagrelor-aspirin (ASA) interaction in the Platelet Inhibition and Patient Outcomes (PLATO) trial, despite this particular interaction being inconclusive. However, a potential ticagrelor-statin interplay occurred and may be important in PLATO, especially considering the remar...

journal_title：Cardiology

authors： Dinicolantonio JJ,Serebruany VL

更新日期：2013-01-01 00:00:00

abstract：OBJECTIVES:To study the care pathway effect on the percentage of patients with ST-elevation myocardial infarction -(STEMI) receiving timely coronary reperfusion and the percentage of STEMI patients receiving optimal secondary prevention. METHODS:A care pathway was implemented by the Collaborative Model for Achieving B...

journal_title：Cardiology

authors： Aeyels D,Bruyneel L,Sinnaeve PR,Claeys MJ,Gevaert S,Schoors D,Panella M,Sermeus W,Vanhaecht K

更新日期：2018-01-01 00:00:00

abstract：:Cell membrane phospholipids, including platelet-activating factor (PAF), participate in the pathogenesis of acute myocardial infarction (AMI). The plasma level of PAF acetylhydrolase (AH) was determined in 18 patients at presentation with AMI before thrombolysis, and the administration of adjunctive therapy, and compa...

journal_title：Cardiology

authors： Serebruany VL,Gurbel PA,Murugesan SR,Lowry DR,Sturm E,Svetlov SI

更新日期：1998-10-01 00:00:00

abstract：:It is well documented that in the treatment of mild or moderate hypertension selective alpha 1-inhibitors such as doxazosin and prazosin lower blood pressure to approximately the same extent as beta-blockers, diuretics, ACE inhibitors and calcium antagonists. However, treatment with selective alpha 1-inhibitors is als...

journal_title：Cardiology

authors： Lund-Johansen P,Hjermann I,Iversen BM,Thaulow E

更新日期：1993-01-01 00:00:00

abstract：:Unlike root abscess, fistula formation is quite uncommon in aortic valve endocarditis. In this report, we describe a patient with subacute bicuspid aortic valve endocarditis complicated by aortic insufficiency, mycotic aneurysms of the aortic root and fistulous communication between the aorta and the left atrium and h...

journal_title：Cardiology

authors： Ozerkan F,Duygu H,Nalbantgil S,Cinar CS

更新日期：2006-01-01 00:00:00

abstract：:The left ventricular function of 14 acromegalic patients was investigated using radionuclide ventriculography. After labeling the red blood cells with 750-1,000 MBq 99mTc-pertechnetate, ECG-triggered left anterior oblique images were recorded. Fourier analysis was then performed on the time-activity curve of the left ...

journal_title：Cardiology

authors： Erbas T,Erbas B,Usman A,Bekdik CF

更新日期：1992-01-01 00:00:00

abstract：:To evaluate the role of adrenal androgens in the development of arteriosclerosis, serum dehydroepiandrosterone sulfate (DHEAS), dehydroepiandrosterone (DHEA), aortic calcification and pulse wave velocity (PWV) were measured in 69 males and 119 females without overt cardiovascular disease. The steroids decreased with a...

journal_title：Cardiology

authors： Ishihara F,Hiramatsu K,Shigematsu S,Aizawa T,Niwa A,Takasu N,Yamada T,Matsuo K

更新日期：1992-01-01 00:00:00

abstract：:A number of cardiac metabolic intermediates, namely, adenosine triphosphate (ATP), H+, phosphocreatine (PCr), inorganic phosphate (Pi), adenosine diphosphate (ADP), and related functions of these intermediates, Gibbs' free energy of ATP hydrolysis (delta G) and phosphorylation ratio [ATP/(ADP.Pi)], are thought to adju...

journal_title：Cardiology

authors： Blum H,Ivanics T,Zhang D,Wroblewski K,Osbakken MD

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND:Multiple studies have quantified the relationship between aortic size and risk of dissection. However, these studies estimated the risk of dissection without accounting for any increase in aortic size from the dissection process itself. OBJECTIVES:This study aims to compare aortic size before and after diss...

journal_title：Cardiology

authors： Mansour AM,Peterss S,Zafar MA,Rizzo JA,Fang H,Charilaou P,Ziganshin BA,Darr UM,Elefteriades JA

更新日期：2018-01-01 00:00:00

abstract：OBJECTIVES:MicroRNAs (miRNAs) are noncoding single-stranded RNA molecules that regulate gene expression in physiological functions, development and disease. In recent studies, three miRNAs have been described as muscle or cardiac specific: miR-1, miR-133, and miR-208, being involved in heart development and disease; bu...

journal_title：Cardiology

authors： Bostjancic E,Zidar N,Stajer D,Glavac D

更新日期：2010-01-01 00:00:00

abstract：:Four biochemical markers, creatine kinase (CK)-MB isoenzyme, myoglobin, myosin light chains and troponin I, were studied in 1,338 patients presenting to the emergency department with chest pain suggestive of coronary artery disease (CAD). One hundred and eighty-seven patients had an acute myocardial infarction (MI). A...

journal_title：Cardiology

authors： Ellestad MH,Startt-Selvester R,Stanton E,VanNatta B,Ahmad J,Gawad Y,Swiger F

更新日期：2000-01-01 00:00:00

abstract：:We assessed the left ventricle function in 24 patients with severe (forced expiratory volume in 1 sec less than 50% of predicted) chronic obstructive pulmonary disease (COPD) and in 21 normal people. We measured the left ventricular systolic time intervals (STI) and echocardiographic left ventricular diameters, volume...

journal_title：Cardiology

authors： Louridas G,Patakas D,Stavropoulos C

更新日期：1981-01-01 00:00:00

abstract：BACKGROUND:Impaired left ventricular diastolic function is a common finding in essential hypertension. METHODS:In order to investigate possible relationships between flow velocity through the mitral valve (E/A; index of left ventricular diastolic function) and 24-hour blood pressure and heart rate variations, 198 pati...

journal_title：Cardiology

authors： Trika CO,Zakopoulos N,Toumanidis ST,Stamatelopoulos SF,Moulopoulos SD

更新日期：2004-01-01 00:00:00

abstract：:Thoracopagus conjoined twins were delivered at 31 weeks gestation by cesarean section. Although there was a single heart, the possibility of salvaging one twin only was contemplated. Echocardiography revealed an A-V canal and suspected transposition of the great vessels. To determine the possibility of surgery, cardia...

journal_title：Cardiology

authors： Kaplan M,Glaser J,Eidelman AI

更新日期：1983-01-01 00:00:00

abstract：CONTEXT:Oral reversible platelet P2Y12 receptor inhibitors (ticagrelor and elinogrel) cause double-digit rates of dyspnea, while irreversible oral antiplatelet drugs (aspirin, ticlopidoine, clopidogrel, and prasugrel) or intravenous glycoprotein IIb/IIIa inhibitors (abciximab, eptifibatide, or tirofiban) do not increas...

journal_title：Cardiology

authors： Serebruany VL,Sibbing D,DiNicolantonio JJ

更新日期：2014-01-01 00:00:00

abstract：:Seventy-two patients aged 2-65 years (mean 20.2) with fixed subaortic stenosis (FSS) are reported. All patients underwent echocardiography and angiography prior to surgical intervention. Sixty-four (89%) had discrete subaortic stenosis (DSS) and 8 (11%) tunnel type stenosis (TSS). Patients with DSS aged 2-65 years (me...

journal_title：Cardiology

authors： Tentolouris K,Kontozoglou T,Trikas A,Brilli S,Chlapoutakis E,Exadactylos N,Pitsavos C,Toutouzas P

更新日期：1999-01-01 00:00:00

abstract：OBJECTIVES:During the past decade, the most common causes of mortality and morbidity were cardiovascular diseases and malignancies. The aim of the current study was to describe the incidence, course of admission, and short-term (30-day) prognosis of patients with and without malignancy, admitted to a tertiary center in...

journal_title：Cardiology

authors： Mazin I,Matetzky S,Shemer L,Fourey D,Fefer P,Segev A,Abu-Much A,Beigel R,Asher E,Platelets and Thrombosis in Sheba (PLATIS) Study Group.

更新日期：2017-01-01 00:00:00

abstract：:The aim of this study was to assess the effects of aerobic exercise on resting and 24-hour blood pressure (BP), left ventricular mass (LVM), plasma fibrinogen and factor VII (FVII). For this purpose 14 sedentary subjects with untreated diastolic BP between 90 and 104 mm Hg completed a 12-week supervised exercise progr...

journal_title：Cardiology

authors： Zanettini R,Bettega D,Agostoni O,Ballestra B,del Rosso G,di Michele R,Mannucci PM

更新日期：1997-09-01 00:00:00

abstract：:In this first clinical report of an idiopathic familial persistently short QT interval (QTI), we describe three members of one family (a 17-year-old female, her 21-year-old brother, and their 51-year-old mother) demonstrating this ECG phenomenon, associated in the 17-year-old with several episodes of paroxysmal atrial...

journal_title：Cardiology

authors： Gussak I,Brugada P,Brugada J,Wright RS,Kopecky SL,Chaitman BR,Bjerregaard P

更新日期：2000-01-01 00:00:00

abstract：:Ventricular assist devices have emerged as the standard of care in treating end-stage heart failure. Their success in bridging patients to transplantation is well documented. The data supporting their ability to bridge patients to recovery is sparser. However, as technology continues to advance, these devices will off...

journal_title：Cardiology

authors： Kherani AR,Maybaum S,Oz MC

更新日期：2004-01-01 00:00:00

abstract：:Advances in echocardiography have made possible simple, noninvasive evaluation of the heart. We report the echocardiographic findings in a case of intrapericardial bronchogenic cyst. The patient, a 36-year-old woman, was hospitalized because of pericarditis. Echocardiography revealed a large unilocular cystic structur...

journal_title：Cardiology

authors： Shimizu M,Takeda R,Mifune J,Tanaka T

更新日期：1990-01-01 00:00:00

abstract：:In this 12-week, double-blind, parallel-group, comparative trial, 57 adult patients with mild-to-moderate hypertension were randomly allocated to receive imidapril or captopril, initially at a dose of 5 mg once a day and 25 mg twice daily, respectively. After 4 weeks of therapy, the dose of each drug was increased twi...

journal_title：Cardiology

authors： Huang PJ,Chien KL,Chen MF,Lai LP,Chiang FT

更新日期：2001-01-01 00:00:00

abstract：:The current study examined the effects of temperature on myocardial pH, contractile function and adenosine triphosphate metabolism, particularly the production of adenosine. We matched intermittent delivery of blood cardioplegia in two groups (hypothermia 15 degrees C; normothermia 37 degrees C), for 2 h of cardiopleg...

journal_title：Cardiology

authors： Shortt KG,Stahl RF,Soller BR,Belle Isle JM,Auerbach AH,Hsi CC

更新日期：1996-11-01 00:00:00

abstract：:Muscle fiber disarray (MFD) has been described as the histologic feature of hypertrophic cardiomyopathy (HC), but it was also found in normal and other abnormal conditions. Its distribution related to the topography of the myocardium has not been described. In this paper, the incidence of MFD in hearts free from HC, t...

journal_title：Cardiology

authors： Milei J,Migliore R,Guerrero F,Pedroza C,Storino R

更新日期：1985-01-01 00:00:00

abstract：:Amiodarone, a highly effective medication for suppressing cardiac rhythm disturbances, may cause pulmonary injury, such as chronic interstitial lung diseases, in 5-15% of the patients who take it. We applied induced sputum (IS), a non-invasive technique, for diagnosing amiodarone-induced pulmonary toxicity. Four patie...

journal_title：Cardiology

authors： Fireman E,Topilsky I,Viskin S,Priel IE

更新日期：2007-01-01 00:00:00

abstract：:We investigated the incidence and determinants of early and late repeat hospitalization for cardiac causes in 378 patients following myocardial revascularization [199 coronary balloon angioplasty (PTCA), 179 coronary bypass surgery (CABG)] in a single cardiovascular center and followed for a median period of 13 years....

journal_title：Cardiology

authors： Halon DA,Rennert HS,Flugelman MY,Jaffe R,Lewis BS

更新日期：2002-01-01 00:00:00

abstract：:Fourteen hypertensive patients and 14 normotensive control subjects were submitted to the oral glucose test and their plasma potassium, glucose and insulin levels were measured. Cardiovascular responses were evaluated by blood pressure and pulse rate measurements. Five of 14 hypertensive patients were hyperinsulinemic...

journal_title：Cardiology

authors： Muscelli EO,Abdalla Saad MJ,Rocha Gontijo JA

更新日期：1991-01-01 00:00:00

abstract：:50 patients, 20 without heart disease and 30 with coronary heart disease (CHD), were studied by kinetocardiography (KCG), before and after administration of isoproterenol (initial dose 2 microgram/min, maximum dose 6 microgram/min). In the control subjects the KCG was unaffected by the drug. In contrast, in most of th...

journal_title：Cardiology

authors： Strozzi C,Cocco G

更新日期：1977-01-01 00:00:00