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Enhancement by cyclosporin A of metastasis from hamster cheek pouch carcinoma.

Abstract：

:Daily intravenous administration of 50 mg/kg cyclosporin A (CsA), after excision of cheek pouch tumors induced with 9,10-dimethyl-1,2-benzanthracene (DMBA), enhanced the incidence of cervical lymph node metastasis to 93%, a significant increase over the rates observed for animals receiving a dosage of 25 mg/kg (43%), and for control animals receiving no CsA (40%). No significant effect was evident on the growth rates of the metastasized tumour cells in the lymph node.

journal_name

Arch Oral Biol

journal_title

Archives of oral biology

authors

Yamada T,Mogi M,Kage T,Ueda A,Nakajima J,Chino T

doi

10.1016/0003-9969(92)90143-v

subject

Has Abstract

pub_date

1992-01-01 00:00:00

pages

593-6

issue

7

eissn

0003-9969

issn

1879-1506

pii

0003-9969(92)90143-V

journal_volume

37

pub_type

杂志文章

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