Heat-induced changes in the rat parotid gland.

Abstract:

:Gland size, amylase activity, total proteins and DNA concentrations were measured in parotid gland during chronic heat exposure (34 degrees C). Subcellular fractionation was performed. Exposure to heat resulted in a decrease in gland size and in DNA concentration; amylase activity/100 mg tissue and amylase specific activity to protein concentration ratio increased. Subcellular fractions, except plasma membrane, decreased significantly. Thus, chronic heat exposure slows down the production of gland constituent proteins, whereas acinar function, e.g. the production and storage of exportable proteins, is not disturbed. The reduced gland size is apparently due to hypoplasia.

journal_name

Arch Oral Biol

journal_title

Archives of oral biology

authors

Horowitz M,Mittelman G,Oron Y

doi

10.1016/0003-9969(83)90059-6

subject

Has Abstract

pub_date

1983-01-01 00:00:00

pages

1037-41

issue

11

eissn

0003-9969

issn

1879-1506

journal_volume

28

pub_type

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