Comparison of various methods for the enumeration of blood cells in urine.


:This study compared the use of conventional urine microscopy, the KOVA system, Neubauer hemacytometry, and the Yellow IRIS for the determination of white blood cell (WBC) and red blood cell (RBC) counts in urine samples. Both KOVA WBC and RBC counts correlated better with the IRIS counts than with conventional microscopy. KOVA WBC counts correlated with Neubauer hemacytometry to the same degree as they did with IRIS WBC counts. The RBC count correlation was fairly similar between KOVA, hemacytometry, and the conventional method. It was concluded that the KOVA system is a suitable replacement for conventional urine microscopy.


J Clin Lab Anal


McGinley M,Wong LL,McBride JH,Rodgerson DO




Has Abstract


1992-01-01 00:00:00












  • Association of pro- and anti-inflammatory cytokines in preeclampsia.

    abstract:INTRODUCTION:The pro- and anti-inflammatory cytokines play crucial role in the development and functions of placenta. Any changes in these cytokines may be associated with many pregnancy-related disorders like preeclampsia. Therefore, the present study is aimed to study the expression of pro-inflammatory (TNF-α, IL-6) ...

    journal_title:Journal of clinical laboratory analysis

    pub_type: 杂志文章


    authors: Aggarwal R,Jain AK,Mittal P,Kohli M,Jawanjal P,Rath G

    更新日期:2019-05-01 00:00:00

  • Evaluation of a bench-top nephelometric immunoassay analyzer.

    abstract::We evaluated the Technicon DPA-1 immunoassay analyzer on its analytical characteristics. Therefore we studied three assays: albumin in cerebrospinal fluid and IgG and transferrin in serum. When tested with the Cusum test for linearity albumin, IgG, and transferrin measurements showed no deviation from linearity. Close...

    journal_title:Journal of clinical laboratory analysis

    pub_type: 杂志文章


    authors: van Rijn JL,van Landeghem AA,Goldschmidt HM

    更新日期:1991-01-01 00:00:00

  • Problems in determining levels of free digoxin in patients treated with digoxin immune FAb.

    abstract::Determination of free digoxin levels in patients treated with digoxin immune FAb has long been a problematic area in clinical laboratory testing. The older radioimmunoassays resulted in inaccurate and variable results due to the competition of the administered drug with the radioactively labelled forms. The 1995 Physi...

    journal_title:Journal of clinical laboratory analysis

    pub_type: 杂志文章


    authors: Honda SA,Rios CN,Murakami L,Morita T,Scottolini AG,Bhagavan NV

    更新日期:1995-01-01 00:00:00

  • Analytical Evaluation of Free Testosterone and Cortisol Immunoassays in Saliva as a Reliable Alternative to Serum in Sports Medicine.

    abstract:BACKGROUND:This study was aimed to investigate whether measurement of free testosterone and cortisol in saliva is a reliable alternative to their assessment in serum for monitoring physical fitness in professional athletes. METHODS:We studied 25 members of the soccer team Parma F.C., playing in Italian major football ...

    journal_title:Journal of clinical laboratory analysis

    pub_type: 杂志文章


    authors: Lippi G,Dipalo M,Buonocore R,Gnocchi C,Aloe R,Delsignore R

    更新日期:2016-09-01 00:00:00

  • Performance characteristics of a transcription-mediated nucleic acid amplification assay for qualitative detection of hepatitis C virus RNA.

    abstract::The detection of hepatitis C virus (HCV) RNA by nucleic acid amplification techniques is the method of choice to differentiate between ongoing and past infection, and can be used to monitor the course of HCV infection. In this study, we evaluated the performance characteristics of a newly developed transcription-media...

    journal_title:Journal of clinical laboratory analysis

    pub_type: 杂志文章


    authors: Ross RS,Viazov SO,Hoffmann S,Roggendorf M

    更新日期:2001-01-01 00:00:00

  • Comparison of BNP and NT-proBNP assays in the approach to the emergency diagnosis of acute dyspnea.

    abstract::N-terminal pro-brain natriuretic peptide (NT-proBNP) and BNP measurement could have a significant role in differentiating dyspnea between cardiac or pulmonary origin in the emergency room. The development of new and different commercial assays for these B-type natriuretic peptides offers the possibility of improving a...

    journal_title:Journal of clinical laboratory analysis

    pub_type: 杂志文章


    authors: Sanz MP,Borque L,Rus A,Vicente B,Ramírez Y,Lasa L

    更新日期:2006-01-01 00:00:00

  • Decrease of HCVRNA after three days of daily interferon treatment is predictive of the virological response at one month.

    abstract::Early monitoring of HCVRNA during interferon treatment may allow clinicians to obtain important information that could help them to adopt therapeutic decisions in individual cases. The hepatitis C virus infection is highly dynamic and a daily high dose of IFN may induce a decline of viremia of 95+/-10% of baseline val...

    journal_title:Journal of clinical laboratory analysis

    pub_type: 临床试验,杂志文章


    authors: Magalini A,Puoti M,Putzolu V,Quiros-Roldan E,Forleo MA,Rossi S,Zaltron S,Spinetti A,Zanini B,Zonaro A,Solfrini R,Carosi G

    更新日期:2000-01-01 00:00:00

  • More sensitive and simpler immune complex transfer enzyme immunoassay for antithyroglobulin IgG in serum.

    abstract::A more sensitive and simpler immune complex transfer enzyme immunoassay for antithyroglobulin IgG in serum and its use for the measurement of antithyroglobulin IgG in healthy subjects and patients with thyroid diseases are described. Antithyroglobulin IgG in test serum was reacted simultaneously with dinitrophenylthyr...

    journal_title:Journal of clinical laboratory analysis

    pub_type: 杂志文章


    authors: Kohno T,Mitsukawa T,Matsukura S,Tsunetoshi Y,Ishikawa E

    更新日期:1989-01-01 00:00:00

  • Multivariable index for assessing the activity and predicting all-cause mortality in antineutrophil cytoplasmic antibody-associated vasculitis.

    abstract:BACKGROUND:So far, there has been no tool to estimate activity at diagnosis and predict all-cause mortality in patients with ANCA-associated vasculitis (AAV). Hence, we determined the initial predictors of them in patients with AAV. METHODS:We retrospectively reviewed the medical records of 182 patients with AAV. Seve...

    journal_title:Journal of clinical laboratory analysis

    pub_type: 杂志文章


    authors: Kim MK,Choi H,Kim JY,Song JJ,Park YB,Lee SW

    更新日期:2020-01-01 00:00:00

  • High-molecular intestinal alkaline phosphatase by agarose gel electrophoresis.

    abstract::The presence of high-molecular intestinal ALP (HIALP) overlapping with bone ALP in the alpha(2)beta region has been demonstrated. In this study we evaluated a method of separating HIALP after its conversion into ALP(5) by the action of protease. Serum samples from patients were mixed with protease at a ratio of 5:1 an...

    journal_title:Journal of clinical laboratory analysis

    pub_type: 杂志文章


    authors: Ooi K,Shiraki K,Morishita Y,Nobori T

    更新日期:2007-01-01 00:00:00

  • Normal blood cells reference intervals of healthy adults at the Gaza Strip-Palestine.

    abstract::Hematological parameters are affected by different factors that include age, sex, smoking, ethnicity, and environmental altitude. It has been justified that each population must establish its own normal reference intervals to be used in clinical assessments and interpretations. Hematological reference intervals for ad...

    journal_title:Journal of clinical laboratory analysis

    pub_type: 杂志文章


    authors: Sirdah MM,Tarazi IS,El Jeadi H,Al Haddad RM

    更新日期:2008-01-01 00:00:00

  • The association of NLRP3 and TNFRSF1A polymorphisms with risk of ankylosing spondylitis and treatment efficacy of etanercept.

    abstract:BACKGROUND:To discover how NLRP3 and TNFRSF1A polymorphisms affect the efficacy of traditional medicine and etanercept for ankylosing spondylitis (AS) patients. METHODS:Single nucleotide polymorphism (SNP) and haplotype analyses were conducted based on determined NLRP3 and TNFRSF1A among AS patients. We subsequently a...

    journal_title:Journal of clinical laboratory analysis

    pub_type: 杂志文章


    authors: Zhao S,Chen H,Wu G,Zhao C

    更新日期:2017-11-01 00:00:00

  • Quality specification and status of internal quality control of cardiac biomarkers in China from 2011 to 2016.

    abstract:BACKGROUND:This study aimed to investigate the status of internal quality control (IQC) for cardiac biomarkers from 2011 to 2016 so that we can have overall knowledge of the precision level of measurements in China and set appropriate precision specifications. METHODS:Internal quality control data of cardiac biomarker...

    journal_title:Journal of clinical laboratory analysis

    pub_type: 杂志文章


    authors: Li T,Wang W,Zhao H,He F,Zhong K,Yuan S,Wang Z

    更新日期:2018-05-01 00:00:00

  • A study of hepcidin and monocyte chemoattractant protein-1 in Egyptian females with systemic lupus erythematosus.

    abstract:BACKGROUND:Lupus nephritis is one of the most serious manifestations of systemic lupus erythematosus (SLE). Novel biomarkers are necessary to enhance the diagnostic accuracy, prognostic stratification, monitoring of treatment response, and detection of early renal flares. METHODS:Our study was conducted on 90 particip...

    journal_title:Journal of clinical laboratory analysis

    pub_type: 杂志文章


    authors: Mohammed MF,Belal D,Bakry S,Marie MA,Rashed L,Eldin RE,El-Hamid SA

    更新日期:2014-07-01 00:00:00

  • Is neutrophil lymphocyte ratio an indicator for proteinuria in chronic kidney disease?

    abstract:BACKGROUND:Recent studies have shown that neutrophil lymphocyte ratio (NLR) is a strong indicator in determining inflammation in cardiac and non-cardiac diseases. We aimed to evaluate the relationship between proteinuria and NLR in chronic kidney disease (CKD) patients without diabetes mellitus (DM). METHODS:Between 2...

    journal_title:Journal of clinical laboratory analysis

    pub_type: 杂志文章


    authors: Binnetoğlu E,Şengül E,Halhallı G,Dindar S,Şen H

    更新日期:2014-11-01 00:00:00

  • Establishment of complete blood count reference intervals for Chinese preschoolers.

    abstract:BACKGROUND:Reference intervals are critical for interpreting test results of a clinical laboratory. The aim of this study was to establish local reference intervals of complete blood count for healthy preschoolers in China. METHODS:Three thousand eight hundred and twenty-one blood specimens from children aged 4 months...

    journal_title:Journal of clinical laboratory analysis

    pub_type: 杂志文章


    authors: Wang GC,Li N,Niu C,Ma WB,Wang ZL,Guo H,Han LH

    更新日期:2017-09-01 00:00:00

  • Assessment of urinary total testosterone production by a highly sensitive time-resolved fluorescence immunoassay.

    abstract::Radioimmunoassay (RIA) that involves purification of the analyte by organic solvent extraction is widely used. Although the extraction RIA is reliable when properly validated, it is time consuming and radioactive, we measure urinary total testosterone with a highly sensitive rapid and accurate time-resolved fluorescen...

    journal_title:Journal of clinical laboratory analysis

    pub_type: 杂志文章


    authors: Bao S,Peng Y,Sheng S,Lin Q

    更新日期:2008-01-01 00:00:00

  • A landscape of circulating long non-coding RNA (lncRNA) expression profile and the predictive value of candidate lncRNAs for disease risk of knee osteoarthritis.

    abstract:BACKGROUND:This study aimed to investigate the plasma long non-coding RNA (lncRNA) expression profile in knee osteoarthritis (KOA) patients and the value of candidate lncRNAs for predicting KOA risk. METHODS:Plasma was obtained for RNA sequencing (RNA-seq) in eight KOA patients and eight healthy controls (Ctrls). Ten ...

    journal_title:Journal of clinical laboratory analysis

    pub_type: 杂志文章


    authors: Liu X,Li M,Zhang B,Zhang N,Feng Q

    更新日期:2020-09-01 00:00:00

  • Validation of a free phenytoin assay on Cobas c501 analyzer using calibrators from Cobas Integra free phenytoin assay by comparing its performance with fluorescence polarization immunoassay for free phenytoin on the TDx analyzer.

    abstract::For many years, fluorescence polarization immunoassay (FPIA) on the TDx analyzer has been used for determination of free phenytoin concentration. Recently Abbott Laboratories decided to discontinue the TDx analyzer and related assays on this analyzer. Free phenytoin assay is also available from Roche Diagnostics for a...

    journal_title:Journal of clinical laboratory analysis

    pub_type: 杂志文章


    authors: Dasgupta A,Davis B,Chow L

    更新日期:2013-01-01 00:00:00

  • Circular RNA LARP4 correlates with decreased Enneking stage, better histological response, and prolonged survival profiles, and it elevates chemosensitivity to cisplatin and doxorubicin via sponging microRNA-424 in osteosarcoma.

    abstract:BACKGROUND:This study aimed to evaluate the association of circular RNA La-related RNA-binding protein 4 (circ-LARP4) with clinical features and prognosis in osteosarcoma patients, and further explore its effect on chemosensitivity in osteosarcoma cells. METHODS:Seventy-two osteosarcoma patients with Enneking stage II...

    journal_title:Journal of clinical laboratory analysis

    pub_type: 杂志文章


    authors: Hu Y,Gu J,Shen H,Shao T,Li S,Wang W,Yu Z

    更新日期:2020-02-01 00:00:00

  • Evaluation of automated basophil counting by using fluorescence-labelled monoclonal antibodies.

    abstract::The shortcomings of current methods of basophil enumeration detract from the clinical value of the basophil count. Moreover, sophisticated and costly techniques of automated basophil counting hardly can be validated for lack of a suitable reference method. We investigated whether a flow cytometric technique using doub...

    journal_title:Journal of clinical laboratory analysis

    pub_type: 杂志文章


    authors: Hübl W,Andert S,Erath A,Streicher J,Bayer PM

    更新日期:1996-01-01 00:00:00

  • An improved microalbumin method (microALB_2) with extended analytical measurement range evaluated on the ADVIA chemistry systems.

    abstract::Quantitative determination of albumin (ALB) in human urine is important to assess kidney functions in a variety of diseases. Recently, Siemens released an improved Microalbumin assay (microALB_2) to measure urinary ALB on the automated, random access ADVIA 1650/1800, ADVIA 2400, and ADVIA 1200 Chemistry Systems. We ev...

    journal_title:Journal of clinical laboratory analysis

    pub_type: 杂志文章


    authors: Datta P,Dasgupta A

    更新日期:2009-01-01 00:00:00

  • Genotyping of samples lacking expected antibodies in ABO blood group.

    abstract::We report nine donations with ABO inconsistency in reverse typing caused by partly or entirely missing antibodies. A and B antigens and antibodies were examined by serological blood typing, and ABO deoxyribonucleic acid (DNA) analyses were performed by sequence-specific priming and sequencing. A B101 allele was demons...

    journal_title:Journal of clinical laboratory analysis

    pub_type: 杂志文章


    authors: Deng ZH,Zeng JQ,Yu Q,Su YQ,Liang YL,Lu L,Zhu WG,Yang BC

    更新日期:2007-01-01 00:00:00

  • The impact of vascular endothelial growth factor +405 C/G polymorphism on long-term outcome and severity of coronary artery disease.

    abstract:BACKGROUND:The association between genetic variations of vascular endothelial growth factor (VEGF) gene and the risk for atherosclerosis has been hypothesized. We aimed to assess the relationship between rs2010963 (+405 C/G) polymorphism and presence, severity, and outcome of coronary artery disease (CAD) in an Iranian...

    journal_title:Journal of clinical laboratory analysis

    pub_type: 杂志文章


    authors: Kalayi Nia S,Ziaee S,Boroumand MA,Sotudeh Anvari M,Pourgholi L,Jalali A

    更新日期:2017-07-01 00:00:00

  • Combined testing for herpes simplex virus and Mycobacterium tuberculosis DNA in cerebrospinal fluid of patients with aseptic meningitis in Burkina Faso, West Africa.

    abstract:BACKGROUND:Little is known about the involvement of herpes simplex virus (HSV) or Mycobacterium tuberculosis (MTB) as potentially curable causes of central nervous system (CNS) infections in sub-Saharan Africa. OBJECTIVE:In this study, we developed a PCR assay dedicated to simultaneous testing of HSV1/HSV2 and MTB in ...

    journal_title:Journal of clinical laboratory analysis

    pub_type: 杂志文章


    authors: Zida S,Kolia-Diafouka P,Kania D,Sotto A,Foulongne V,Bolloré K,Ouangraoua S,Méda N,Carrère-Kremer S,Van de Perre P,Tuaillon E

    更新日期:2019-03-01 00:00:00

  • Histocompatibility screening by molecular techniques: use of polymerase chain reaction products and heteroduplex formation.

    abstract::Novel molecular approaches have recently become available allowing improved major histocompatibility complex (MHC) matching of potential allogeneic bone marrow donors and recipients. Current cellular and serological assays are hindered by aberrant cell populations and limited reagents which only detect an individuals'...

    journal_title:Journal of clinical laboratory analysis

    pub_type: 杂志文章


    authors: Rubocki RJ,Wisecarver JL,Hook DD,Cox SM,Beisel KW

    更新日期:1992-01-01 00:00:00

  • An immunoenzymometric assay for a CA125-like antigen, CA602.

    abstract::An immunoenzymometric assay (IEMA) for a new CA125-like antigen, CA602, was developed. Five monoclonal antibodies raised against a human ovarian carcinoma cell line could detect their respective antigens in the sera of ovarian carcinoma patients. The antigen levels detected in serum by the various antibodies correlate...

    journal_title:Journal of clinical laboratory analysis

    pub_type: 杂志文章


    authors: Mochizuki H,Sato I,Nagoya K,Furusako S,Yamauchi T,Masuko H,Sato H,Morishita H,Yajima M,Sasaki H

    更新日期:1992-01-01 00:00:00

  • Comparative study of total protein, and total and lipid-associated serum sialic acid levels in patients with type 2 diabetes mellitus.

    abstract::The aim of the present study was to investigate the serum total protein (TP), total sialic acid (TSA), lipid-associated sialic acid (LSA), LSA/TP, and LSA/TP values in type 2 diabetes mellitus (DM) patients. Two study groups (healthy controls and type 2 DM subjects) were examined. For the type 2 DM group, 120 patients...

    journal_title:Journal of clinical laboratory analysis

    pub_type: 杂志文章


    authors: Ekin S,Meral I,Gunduz H,Mert N

    更新日期:2003-01-01 00:00:00

  • Differentiation of Candida dubliniensis from Candida albicans on rosemary extract agar and oregano extract agar.

    abstract::Candida dubliniensis is a recently described pathogenic species which shares many phenotypic features with Candida albicans and therefore, may be misidentified in microbiological laboratories. Because molecular methods can be onerous and unfeasible in routine mycological laboratories with restricted budgets such as th...

    journal_title:Journal of clinical laboratory analysis

    pub_type: 杂志文章


    authors: de Loreto ES,Pozzatti P,Alves Scheid L,Santurio D,Morais Santurio J,Alves SH

    更新日期:2008-01-01 00:00:00

  • Increased concentration of serum periostin is associated with poor outcome of patients with aneurysmal subarachnoid hemorrhage.

    abstract:OBJECTIVE:To explore the role of serum periostin in patients with aneurysmal subarachnoid hemorrhage (aSAH). METHOD:We conducted a retrospective study and 124 aSAH patients treated in Shenzhen People's hospital during March 1st 2015 to December 30th 2016 were included. Baseline information, neurological status and cli...

    journal_title:Journal of clinical laboratory analysis

    pub_type: 杂志文章


    authors: Luo W,Wang H,Hu J

    更新日期:2018-06-01 00:00:00