Pilocarpine-induced increases in the activity of 6-phosphofructo-2-kinase and the fructose-2,6-bisphosphate content of rat salivary glands.

Abstract:

:The activity of 6-phosphofructo-1-kinase (PFK-1), an important regulatory enzyme of glycolysis, was determined after injection of the sialagogue pilocarpine. The fructose-2,6-bisphosphate content of the glands and 6-phosphofructo-2-kinase (PFK-2) activity were also measured. The increase in PFK-1 activity after pilocarpine treatment was likely to be due to the increase in the content of its potent modulator, fructose-2,6-bisphosphate. This in turn was assumed to be due to the increase in the activity of the active form of PFK-2.

journal_name

Arch Oral Biol

journal_title

Archives of oral biology

authors

Nicolau J,de Souza DN,Martins HR

doi

10.1016/0003-9969(92)90104-g

subject

Has Abstract

pub_date

1992-01-01 00:00:00

pages

483-7

issue

6

eissn

0003-9969

issn

1879-1506

pii

0003-9969(92)90104-G

journal_volume

37

pub_type

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