Effects of phosphoprotein on collagen fibril formation in vitro.

Abstract:

:Transmission electron microscopy showed that when either dentinal phosphoprotein or calcium-treated phosphoprotein or phosvitin were introduced during type I collagen fibrillogenesis the fibrils formed were significantly wider and the cross-banding was more distinct than in the absence of phosphoprotein. The collagen fibril width also increased with increasing concentrations of these molecules. When either bovine serum albumin (BSA) or dephosphorylated dentine phosphoprotein were used, no differences in the fibril characteristics were seen when compared to the controls that contained no phosphoprotein or BSA. When these dialysed matrices were placed into mineralizing solutions, no mineral was observed in any of the samples.

journal_name

Arch Oral Biol

journal_title

Archives of oral biology

authors

Clarkson BH,McCurdy SP,Gaz D,Hand AR

doi

10.1016/0003-9969(93)90068-w

subject

Has Abstract

pub_date

1993-09-01 00:00:00

pages

737-43

issue

9

eissn

0003-9969

issn

1879-1506

pii

0003-9969(93)90068-W

journal_volume

38

pub_type

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