An in-vitro system for studying the effect of variable compressive forces on the mandibular condylar cartilage of the rat.

Abstract:

:An in-vitro system enabled variable range of continuous and intermittent compressive forces to be applied to the cartilage of 4-day-old rats under serum-free culture conditions. A continuous compressive force below 3 g did not affect the growth of the cartilage; when the force exceeded 3 g, growth ceased. Under an intermittent compressive force up to 8 g, growth continued, but at a lower rate; over 8 g, growth ceased. When growth-restricting compression was removed or reduced, growth was reactivated until a new balance was achieved. The normal architecture of the different zones was altered in the non-compressed in-vitro controls, but not in cultured cartilage during the application of these compressive forces.

journal_name

Arch Oral Biol

journal_title

Archives of oral biology

authors

Copray JC,Jansen HW,Duterloo HS

doi

10.1016/0003-9969(85)90002-0

subject

Has Abstract

pub_date

1985-01-01 00:00:00

pages

305-11

issue

4

eissn

0003-9969

issn

1879-1506

journal_volume

30

pub_type

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