Determination of plasma delta-aminolaevulinic acid levels. Applications.

Abstract:

:Determination of plasma delta-aminolaevulinic acid levels is of interest for the diagnosis of disorders of heme biosynthesis. We describe a reliable method for the determination of this parameter, based on a modification of the original method of Mauzerall and Granick. Analytical criteria are defined and the reference range used, established using data from 40 subjects, was 0.30 to 1.20 mumol/l. Results in patients with porphyria or lead poisoning and in those treated with haemodialysis or anticonvulsants indicate that this determination could be used principally in the diagnosis and management of acute porphyrias and in the early laboratory diagnosis of lead poisoning.

journal_name

Ann Biol Clin (Paris)

authors

Goujon R,Philibert E,Bernard P,Normand J,Boucherat M

subject

Has Abstract

pub_date

1992-01-01 00:00:00

pages

675-7

issue

10-11

eissn

0003-3898

issn

1950-6112

journal_volume

50

pub_type

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