[Blood sampling using "dried blood spot": a clinical biology revolution underway?].

Abstract:

:Blood testing using the dried blood spot (DBS) is used since the 1960s in clinical analysis, mainly within the framework of the neonatal screening (Guthrie test). Since then numerous analytes such as nucleic acids, small molecules or lipids, were successfully measured on the DBS. While this pre-analytical method represents an interesting alternative to classic blood sampling, its use in routine is still limited. We review here the different clinical applications of the blood sampling on DBS and estimate its future place, supported by the new methods of analysis as the LC-MS mass spectrometry.

journal_name

Ann Biol Clin (Paris)

authors

Hirtz C,Lehmann S

doi

10.1684/abc.2014.1007

subject

Has Abstract

pub_date

2015-01-01 00:00:00

pages

25-37

issue

1

eissn

0003-3898

issn

1950-6112

pii

abc.2014.1007

journal_volume

73

pub_type

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