A novel murine PDGF-D splicing variant results in significant differences in peptide expression and function.

abstract：:Alveolar epithelial type I and type II cells (AEC I and II) are closely aligned in alveolar surface. There is much interest in the precise identification of AEC I and II in order to separate and evaluate functional and other properties of these two cells. This study aims to identify specific AEC I and AEC II cell mark...

journal_title：Biochemical and biophysical research communications

authors： Chen Z,Jin N,Narasaraju T,Chen J,McFarland LR,Scott M,Liu L

更新日期：2004-07-02 00:00:00

abstract：:Lon protease has been well studied in many aspects; however, the DNA-binding specificity of Lon in prokaryotes has not been clearly identified. Here we examined the DNA-binding activity of Lon protease alpha-domains from Brevibacillus thermoruber (Bt), Bacillus subtilis (Bs), and Escherichia coli (Ec). MALDI-TOF mass ...

journal_title：Biochemical and biophysical research communications

authors： Lin YC,Lee HC,Wang I,Hsu CH,Liao JH,Lee AY,Chen C,Wu SH

更新日期：2009-10-09 00:00:00

abstract：:Various dehydrogenation polymers (the so-called synthetic lignins) were synthesized from four different phenylpropenoids by endwise and bulk polymerizations and investigated for their anti-influenza virus activity. All of these materials suppressed the plaque formation of influenza virus infecting MDCK cells and the R...

journal_title：Biochemical and biophysical research communications

authors： Sakagami H,Nagata K,Ishihama A,Oh-hara T,Kawazoe Y

更新日期：1990-11-15 00:00:00

abstract：:Overexpression of AtNTRC (AtNTRC(OE)) in Arabidopsis thaliana led to a freezing and cold stress tolerance, whereas a knockout mutant (atntrc) showed a stress-sensitive phenotype. Biochemical analyses showed that the recombinant AtNTRC proteins exhibited a cryoprotective activity for malate dehydrogenase and lactic deh...

journal_title：Biochemical and biophysical research communications

authors： Moon JC,Lee S,Shin SY,Chae HB,Jung YJ,Jung HS,Lee KO,Lee JR,Lee SY

更新日期：2015-08-07 00:00:00

abstract：:Cullin-RING ligases (CRLs) regulate diverse cellular functions such as cell cycle progression and cytokine signaling by ubiquitinating key regulatory proteins. The activity of CRLs is controlled by Nedd8 modification of the cullin subunits. Recent reports have suggested that CAND1, which specifically binds to unmodifi...

journal_title：Biochemical and biophysical research communications

authors： Min KW,Kwon MJ,Park HS,Park Y,Yoon SK,Yoon JB

更新日期：2005-09-02 00:00:00

abstract：:The presence and localization of mitochondrial calmodulin was directly proved immuno-electron microscopically by the protein A-gold technique. In the ultra-pure mitochondria the complexes of anti-calmodulin antibody and protein A-gold clearly showed the localization of mitochondrial calmodulin on the inner membrane an...

journal_title：Biochemical and biophysical research communications

authors： Hatase O,Doi A,Itano T,Matsui H,Ohmura Y

更新日期：1985-10-15 00:00:00

abstract：:The majority of studies on possible roles for collagen hydrolysates in human health have focused on their effects on bone and skin. Hydroxyprolyl-glycine (Hyp-Gly) was recently identified as a novel collagen hydrolysate-derived dipeptide in human blood. However, any possible health benefits of Hyp-Gly remain unclear. ...

journal_title：Biochemical and biophysical research communications

authors： Kitakaze T,Sakamoto T,Kitano T,Inoue N,Sugihara F,Harada N,Yamaji R

更新日期：2016-09-23 00:00:00

abstract：:Circadian variations in the levels of prostaglandins (PGs) D2, E2, and F2 alpha were studied in the cerebrospinal fluid (CSF) of rats. We collected CSF samples from the cisterna magna of anesthetized rats at different clock-hours (1000, 1400, 1800, 2200, 0200, and 0600 hr), and measured the concentrations of the three...

journal_title：Biochemical and biophysical research communications

authors： Pandey HP,Ram A,Matsumura H,Satoh S,Hayaishi O

更新日期：1995-08-15 00:00:00

abstract：:Ritonavir, an inhibitor of HIV-1 protease, has been reported to also inhibit the Ca2+-dependent cysteine protease, calpain. We have investigated these claims with an in vitro study of the effect of ritonavir on the m-calpain and mu-calpain isoforms. Ritonavir failed to block either autolytic or hydrolytic calpain acti...

journal_title：Biochemical and biophysical research communications

authors： Cuerrier D,Nie Z,Badley AD,Davies PL

更新日期：2005-02-04 00:00:00

abstract：:Human adipose-derived mesenchymal stem cells (hASCs) are attractive cell source for skin tissue engineering. The aim of this study was to investigate the effects of low-level light therapy (LLLT) on transplanted cluster hASC in a skin wound animal model. The hASCs were cultured in monolayer or clusters. The LLLT, hASC...

journal_title：Biochemical and biophysical research communications

authors： Park IS,Chung PS,Ahn JC

更新日期：2015-07-03 00:00:00

abstract：:Bone morphogenetic proteins (BMPs) play important roles in osteoblast differentiation and maturation. In mammals, the BMP-induced receptor-regulated Smads form complexes with Smad4. These complexes translocate and accumulate in the nucleus, where they regulate the transcription of various target genes. However, the fu...

journal_title：Biochemical and biophysical research communications

authors： Shimada K,Ikeda K,Ito K

更新日期：2009-12-18 00:00:00

abstract：:Three different domains of human sperm membrane, viz., the hydrophobic domains, the aqueous compartments and the surface proteins were probed to evaluate the molecular dynamics in these microenvironments in normal as well as oligospermic cases. Decreased rotational motion of the stearic spin-labels, designated rigid l...

journal_title：Biochemical and biophysical research communications

authors： Sinha S,Kumar GP,Laloraya M

更新日期：1994-01-14 00:00:00

abstract：:Hypothetical lambda protein ORF314 shows significant homology with the carboxyl end of phage T4 tail-fiber protein gp37. Homology can also be demonstrated between hypothetical lambda protein ORF194 and a fragment of bacteriophage T4 protein gp38. This sequence homology is also reflected in the genomic sequences of the...

journal_title：Biochemical and biophysical research communications

authors： George DG,Yeh LS,Barker WC

更新日期：1983-09-30 00:00:00

abstract：:The process in which nucleotide is buried into the active site of heavy meromyosin was studied with stopped-flow apparatus by monitoring the time-course of the large fluorescence increase of 1,N6-ethenoadenosine triphosphate (epsilon-ATP) when it binds from acrylamide-containing solutions. We have recently reported th...

journal_title：Biochemical and biophysical research communications

authors： Ando T,Duke JA

更新日期：1983-08-30 00:00:00

abstract：:Histone-H1 purified from rat skeletal muscle is a relatively potent inhibitor of peptide chain initiation in a cell free system, the rabbit reticulocyte lysate (50% inhibition at approximately 0.4 microM). H1 does not inhibit formation of the ternary complex nor its attachment to 40S ribosomes; the data are compatible...

journal_title：Biochemical and biophysical research communications

authors： O'Leary NE,Cheema IR,Moore K,Mehard WB,Buse MG

更新日期：1987-04-14 00:00:00

abstract：:The gel retardation assay with a single-stranded oligo-DNA of cAMP-response element (CRE) in a somatostatin promoter region was selected to examine the possibility of transcriptional regulation of cAMP-inducible genes by chronic morphine or ethanol treatment of NG108-15 cells. When the nuclear extracts from the cells ...

journal_title：Biochemical and biophysical research communications

authors： Osugi T,Taniura H,Ikemoto M,Miki N

更新日期：1991-01-15 00:00:00

abstract：:Sterol carrier protein X (SCPx) is a peroxisomal protein with both lipid transfer and thiolase activity. Treatment of mouse adrenal Y1 cells with cAMP for 24h caused a significant induction of SCPx mRNA levels. Reporter gene studies demonstrated that treatment with cAMP and SF-1 was able to activate the SCPx promoter....

journal_title：Biochemical and biophysical research communications

authors： Lopez D,Niesen M,Bedi M,Hale D,McLean MP

更新日期：2007-06-01 00:00:00

abstract：:The retinoid-related orphan receptor gamma (RORgamma) has been shown to function as a positive regulator of transcription in many cell lines. Transcriptional activation by nuclear receptors involves recruitment of co-activators that interact with receptors through their LXXLL motifs (NR box). In this study, we analyze...

journal_title：Biochemical and biophysical research communications

authors： Kurebayashi S,Nakajima T,Kim SC,Chang CY,McDonnell DP,Renaud JP,Jetten AM

更新日期：2004-03-19 00:00:00

abstract：:Multidrug-resistant cells are characterized by the presence of P-glycoprotein on the plasma membrane, which binds and probably transports antitumor agents outside the cells. P-glycoprotein is also present in various normal tissues such as the adrenal gland. To investigate the physiological function of P-glycoprotein, ...

journal_title：Biochemical and biophysical research communications

authors： Naito M,Yusa K,Tsuruo T

更新日期：1989-02-15 00:00:00

abstract：:Insulin gene was induced into differentiated hepatic cell line. These cells released immunoreactive insulin (IRI) of which molecular weight was greater than mature insulin. The secretion of IRI was responsive to glucose concentration and inhibited by glucose metabolism antagonist, 2-deoxy glucose (2-DOG). The mRNA of ...

journal_title：Biochemical and biophysical research communications

authors： Hayashi M,Taguchi M,Fujita T

更新日期：1997-04-17 00:00:00

abstract：:Poly(ADP-ribose) polymerase-1 (PARP-1) is a nuclear enzyme that is involved in DNA repair and activated by DNA damage. When activated, PARP-1 consumes NAD(+) to form ADP-ribose polymers on acceptor proteins. Extensive activation of PARP-1 leads to glycolytic blockade, energy failure, and cell death. These events have ...

journal_title：Biochemical and biophysical research communications

authors： Ying W,Garnier P,Swanson RA

更新日期：2003-09-05 00:00:00

abstract：:Transgenic mouse which produces human alpha-fetoprotein (AFP) ubiquitously was used to study carbohydrate structures of AFP produced by various tissues as well as that in the serum. A series of tissues from the transgenic mouse were cultured in vitro and the AFP produced was analyzed by affinity electrophoreses with 4...

journal_title：Biochemical and biophysical research communications

authors： Koyama Y,Sakai M,Kitagawa T,Taketa K,Nishi S

更新日期：1996-06-25 00:00:00

abstract：:Histone deacetylase inhibitors (HDACIs) are promising anti-tumor agents that selectively induce cell cycle arrest, differentiation and/or apoptosis of tumor cells. Fundamentally, HDACIs are proposed to function by activating the transcription of genes, including the potent cyclin dependent kinase inhibitor p21(WAF1). ...

journal_title：Biochemical and biophysical research communications

authors： Hirsch CL,Ellis DJ,Bonham K

更新日期：2010-11-26 00:00:00

abstract：:Platelet-derived growth factor-D (PDGF-D) is a more recent recognized growth factor involved in the regulation of several cellular processes, including cell proliferation, transformation, invasion, and angiogenesis by binding to and activating its cognate receptor PDGFR-β. After bile duct ligation or in the carbon tet...

journal_title：Biochemical and biophysical research communications

authors： Borkham-Kamphorst E,Alexi P,Tihaa L,Haas U,Weiskirchen R

更新日期：2015-02-13 00:00:00

abstract：:Subpeptin JM4-A and subpeptin JM4-B are two novel antimicrobial peptides produced by Bacillus subtilis JM4. To identify putative genes involved in their production, degenerate PCR primers targeted to conserved motifs of nonribosomal peptide synthetases (NRPSs) were used. A resulting 1.2 kb PCR product had high sequenc...

journal_title：Biochemical and biophysical research communications

authors： Wu S,Zhong J,Huan L

更新日期：2006-06-16 00:00:00

abstract：:Hepatocyte growth factor (HGF) specifically activates Met tyrosine kinase receptor, leading to mitogenic, motogenic, and morphogenic responses in a wide variety of cells. To know a role of HGF in Xenopus embryogenesis, loss-of-function mutation was introduced by dominant expression of truncated tyrosine kinase-negativ...

journal_title：Biochemical and biophysical research communications

authors： Aoki S,Takahashi K,Matsumoto K,Nakamura T

更新日期：1997-05-08 00:00:00

abstract：:We have recently isolated a rat homologue of the Caenorrhabditis elegans lin-10 product. Although rat lin-10 is expressed in the cytosol and membrane fractions of various tissues, it is distributed only in the membrane fraction in brain where it is enriched in the synaptic plasma membrane and postsynaptic density frac...

journal_title：Biochemical and biophysical research communications

authors： Ide N,Hata Y,Hirao K,Irie M,Deguchi M,Yao I,Satoh A,Wada M,Takahashi K,Nakanishi H,Takai Y

更新日期：1998-03-06 00:00:00

abstract：:We had earlier reported a uteroglobin promoter-binding factor in nuclei from progesterone-stimulated rabbit endometrium that was inhibited by a factor in nuclei without progesterone stimulation or from non-target tissues (Rider, V., and Bullock, D.W., 1988. Biochem. Biophys. Res. Comm. 156, 1368-1375). In the course o...

journal_title：Biochemical and biophysical research communications

authors： Daniel PB,Molloy C,Rayner JC,Hill AM,Bullock DW

更新日期：1994-10-14 00:00:00

abstract：:Mesenchymal stem cells (MSCs) are a heterogeneous subset of stromal stem cells isolated from many adult tissues. Previous studies reported that MSCs can differentiate to both mesodermal and neural lineages by a phenomenon referred to as ''dedifferentiation'' or ''transdifferentiation''. However, since MSCs have only b...

journal_title：Biochemical and biophysical research communications

authors： Morikawa S,Mabuchi Y,Niibe K,Suzuki S,Nagoshi N,Sunabori T,Shimmura S,Nagai Y,Nakagawa T,Okano H,Matsuzaki Y

更新日期：2009-02-20 00:00:00

abstract：:Different methylations of cloned human ornithine decarboxylase gene with restriction methylases in vitro before transfection greatly reduced the transient expression of ODC in Chinese hamster ovary cells. Single methylation of the gene with Hpa II (CCGG) methylase decreased the transiently expressed peak activity by a...

journal_title：Biochemical and biophysical research communications

authors： Halmekytö M,Hirvonen A,Wahlfors J,Alhonen L,Jänne J

更新日期：1989-07-14 00:00:00