Measuring the severity of rosacea: a review.


BACKGROUND:Assessment of severity is essential in the clinical care of rosacea patients and in the research on rosacea. OBJECTIVE:To determine the range of methods used to assess rosacea severity in clinical trials. METHODS:The medical literature from 1965 through 2001 was searched for rosacea clinical trials using MEDLINE and published citations. Forty-seven articles were reviewed. RESULTS:The most frequently assessed signs of rosacea were papules/pustules (43 studies), erythema (35), and telangiectasia (24). Other signs and symptoms of rosacea and adverse reactions to therapies were assessed in 27 studies. Counts of papules/pustules were conducted in 34 studies. Four-point scales were the most frequently used assessment tools for erythema (17) and telangiectasia (11). Other frequently used techniques included global assessment by clinicians (29) and by patients (21), and photography (13). CONCLUSIONS:At present, there are no standard validated tools for assessing the severity of rosacea or its signs or symptoms.


Int J Dermatol


Gessert CE,Bamford JT




Has Abstract


2003-06-01 00:00:00














  • Calcifying acne lesions.

    abstract::Cutaneous calcium deposition can occur in long-term inflammation. The deposition of calcium in long-standing acne may produce either small pigmented nodules or no visible lesions. The former type is or no visible lesions. The former type is much less common, with the nodules containing particulate spheres of mineral w...

    journal_title:International journal of dermatology

    pub_type: 杂志文章


    authors: Basler RS,Watters JH,Taylor WB

    更新日期:1977-11-01 00:00:00

  • Psoriasis and pregnancy: hormone and immune system interaction.

    abstract:BACKGROUND:Various hormonal states are known to be associated with the waxing and waning of psoriasis. Patients with psoriasis commonly experience changes in their cutaneous disease during pregnancy or post partum. OBJECTIVE:We evaluated 100 women with psoriasis by questionnaire and interview. The women had been seen ...

    journal_title:International journal of dermatology

    pub_type: 杂志文章


    authors: Boyd AS,Morris LF,Phillips CM,Menter MA

    更新日期:1996-03-01 00:00:00

  • Histologic features seen in changing nevi after therapy with an 810 nm pulsed diode laser for hair removal in patients with dysplastic nevi.

    abstract:BACKGROUND:The majority of lasers used for hair removal target melanin as the chromophore. In contrast with other cutaneous applications of lasers, lasers used for hair removal must generate a limited, controlled degree of thermal damage to permanently remove hairs. AIM:To remove excess back hair from two male patient...

    journal_title:International journal of dermatology

    pub_type: 杂志文章


    authors: Soden CE,Smith K,Skelton H

    更新日期:2001-08-01 00:00:00

  • The risk of malignancy or progression of existing malignancy in patients with psoriasis treated with biologics: case report and review of the literature.

    abstract::There is some debate regarding the risk of developing malignancy and progression of malignancy in patients with psoriasis treated with biologics. The lack of extensive, long-term, and large studies, including patients with psoriasis, to assess these aforementioned risks makes it difficult to ascertain the safety profi...

    journal_title:International journal of dermatology

    pub_type: 杂志文章,评审


    authors: Patel S,Patel T,Kerdel FA

    更新日期:2016-05-01 00:00:00

  • Does needle biopsy cause an increased risk of extracapsular extension in the diagnosis of metastatic lymph node in melanoma?

    abstract:BACKGROUND:Needle biopsy is a rapid, reliable, and reproducible procedure for histological confirmation of metastatic melanoma localization. Nonetheless, this procedure presents a theoretical risk of a mechanical weakening of the lymph node capsule with perinodal tumor seeding. The objective of the study was to evaluat...

    journal_title:International journal of dermatology

    pub_type: 杂志文章


    authors: Claro G,Meyer N,Meresse T,Gangloff D,Grolleau JL,Chaput B

    更新日期:2018-04-01 00:00:00

  • Lepromatous and tuberculoid leprosy: clinical presentation and cytokine responses.

    abstract:OBJECTIVE:This study analyzes the major clinical characteristics of patients with active leprosy in relation to the in vitro immune response to the T-lymphocyte activator anti-CD3. METHODS:Thirty-eight patients with an established diagnosis of leprosy were classified according to the Ridley and Jopling table. Peripher...

    journal_title:International journal of dermatology

    pub_type: 杂志文章


    authors: Ochoa MT,Valderrama L,Ochoa A,Zea A,Escobar CE,Moreno LH,Falabella R

    更新日期:1996-11-01 00:00:00

  • Topical zinc therapy for acne vulgaris.

    abstract::A double-blind study of 30 patients with mild to moderate acne vulgaris was conducted to evaluate the efficacy of a topically applied 2% zinc sulfate solution for acne therapy. Over a 12-week period, no difference was noted between placebo- and zinc-treated participants in regard to either the number or type of acne l...

    journal_title:International journal of dermatology

    pub_type: 临床试验,杂志文章


    authors: Cochran RJ,Tucker SB,Flannigan SA

    更新日期:1985-04-01 00:00:00

  • The profile of fogo selvagem (endemic pemphigus foliaceus) at the University Hospital of Brasilia-Brazil. Epidemiological and clinical considerations.

    abstract:BACKGROUND:Endemic pemphigus foliaceus (EPF) or fogo selvagem (FS) is an endemic autoimmune disease, characterized by flaccid bullae induced by IgG(4) subclass antibodies. The authors demonstrate the epidemiological and clinical status of patients who have been followed at the University Hospital of Brasilia (HUB) for ...

    journal_title:International journal of dermatology

    pub_type: 杂志文章


    authors: Ribeiro AM,Alvarez RR,Friedman H,Campbell I,Cooperative Group osn Fogo Selvagem Research.

    更新日期:2005-04-01 00:00:00

  • Seasonal variations in the severity of acne vulgaris.

    abstract:BACKGROUND AND OBJECTIVE:The improvement of acne in summertime or the aggravation of acne in winter is a traditional dermatologic opinion. Ultraviolet rays are thought to be beneficial in the treatment of acne. In the existing literature there is no proof of this. The purpose of this study was to find out whether or no...

    journal_title:International journal of dermatology

    pub_type: 杂志文章


    authors: Gfesser M,Worret WI

    更新日期:1996-02-01 00:00:00

  • Severe infliximab-induced psoriasis treated with adalimumab switching.

    abstract:BACKGROUND:Antitumor necrosis factor (anti-TNF) agents are a well-established treatment for various medical conditions, including psoriasis and psoriatic arthritis. However, anti-TNF agents may themselves induce psoriasis in some patients. METHODS:The authors report two cases of patients with severe and refractory inf...

    journal_title:International journal of dermatology

    pub_type: 杂志文章


    authors: Faillace C,Duarte GV,Cunha RS,de Carvalho JF

    更新日期:2013-02-01 00:00:00

  • A retrospective review of cutaneous lymphoma in Botswana.

    abstract:BACKGROUND:Primary cutaneous lymphoma (PCL) represents a heterogeneous collection of non-Hodgkin lymphomas originating in the skin. Our study describes the clinical and histological findings of cutaneous lymphoma within Botswana to expand the paucity of data on this rare disease in sub-Saharan Africa. METHODS:We condu...

    journal_title:International journal of dermatology

    pub_type: 杂志文章


    authors: Rodriguez O,Sowash M,Mosojane KI,Ralefala T,Grover S,Haun P,Kovarik C,Williams VL

    更新日期:2020-03-01 00:00:00

  • Dextranomer in dermatologic conditions.

    abstract::Dextranomer, a high molecular weight dextran derivative, was evaluated in 43 patients, and found to be the treatment of choice for decubitus ulcers. It is useful in most leg ulcers and cutaneous wounds, and can aid in the nursing care of terminal patients with gangrene or uclerating carcinoma. Dextranomer hastens the ...

    journal_title:International journal of dermatology

    pub_type: 临床试验,杂志文章


    authors: Parish LC,Witkowski JA

    更新日期:1979-07-01 00:00:00

  • Clinicopathologic features of ulcerative-atrophic sarcoidosis.

    abstract:BACKGROUND:Sarcoidosis is a chronic granulomatous disease of unknown etiology. Cutaneous disease is common and includes two clinicopathologic categories: granulomatous infiltration or a reactive phenomenon. In the granulomatous infiltrative group, clinical manifestations can be variable. Ulcers in sarcoidosis are uncom...

    journal_title:International journal of dermatology

    pub_type: 杂志文章


    authors: Yoo SS,Mimouni D,Nikolskaia OV,Kouba DJ,Sauder DN,Nousari CH

    更新日期:2004-02-01 00:00:00

  • Omalizumab for atopic dermatitis: case series and a systematic review of the literature.

    abstract::Omalizumab is a recombinant humanized monoclonal antibody targeting the high-affinity Fc receptor of IgE, registered for the treatment of chronic spontaneous urticaria and severe allergic asthma. We present a case series of nine patients with atopic dermatitis (AD) treated off-label with omalizumab and a systematic re...

    journal_title:International journal of dermatology

    pub_type: 杂志文章,评审


    authors: Holm JG,Agner T,Sand C,Thomsen SF

    更新日期:2017-01-01 00:00:00

  • Cutaneous toxoplasmosis.

    abstract::Nine patients with cutaneous toxoplasmosis had slowly regressing erythema-multiforme-like eruptions or lichenoid, papulonodular and purpurictelangiectatic disorders. The most common histologic finding was subacute histiolymphocytic perivasculitis with frequent demonstration of the parasite. Another group of patients s...

    journal_title:International journal of dermatology

    pub_type: 杂志文章


    authors: Binazzi M,Papini M

    更新日期:1980-07-01 00:00:00

  • Discordance of skin and muscle involvement in dermatomyositis.

    abstract::The skin manifestations of dermatomyositis infrequently occur without the myositis. A 24-year-old woman presented with concordance of the skin and muscle components of dermatomyositis, followed by a remission of the myositis with a persistence of significant rash for 17 years, finally presenting with a flare of both s...

    journal_title:International journal of dermatology

    pub_type: 杂志文章


    authors: Gertner E,Urowitz MB

    更新日期:1985-10-01 00:00:00

  • Cutaneous manifestations associated with HTLV-1 infection.

    abstract::Skin lesions are frequent in human T-cell lymphotropic virus type 1 (HTLV-1) infection and may constitute an alert for the diagnosis of this condition. The most severe skin diseases related to this virus are adult T-cell leukemia/lymphoma (ATLL), an aggressive form of leukemia/lymphoma that fails to respond to chemoth...

    journal_title:International journal of dermatology

    pub_type: 杂志文章,评审


    authors: Bittencourt AL,de Oliveira Mde F

    更新日期:2010-10-01 00:00:00

  • Nail pigmentation due to hydroxycarbamide.

    abstract::A 47-year-old male developed both longitudinal melanonychia and periungual hyperpigmentation 6 months after initiation of hydroxycarbamide (synonym: hydroxyurea) therapy for chronic myeloproliferative disease. Based on the clinical symptoms observed in this patient, the broad differential diagnostic spectrum of hyperp...

    journal_title:International journal of dermatology

    pub_type: 杂志文章


    authors: Ceulen RP,Frank J,Poblete-Gutiérrez P

    更新日期:2007-11-01 00:00:00

  • Factors affecting patient presentation at a national dermatology referral clinic in Kampala, Uganda.

    abstract:BACKGROUND:This study sought to gain a better understanding of the patient population in Kampala and was further designed to elucidate barriers that may delay individuals from receiving proper dermatologic care. METHODS:The study took place at the dermatovenereology clinic of a tertiary care hospital in Kampala. New a...

    journal_title:International journal of dermatology

    pub_type: 杂志文章


    authors: Song ES,Musinguzi P,Dieckhaus KD

    更新日期:2017-03-01 00:00:00

  • Isotretinoin treatment for folliculitis decalvans: a retrospective case-series study.

    abstract:BACKGROUND:The literature includes only a few reports of oral isotretinoin for the treatment of folliculitis decalvans (FD). This study aimed to determine the most effective dose and duration of oral isotretinoin monotherapy for achieving remission in FD patients. METHODS:This retrospective case series study included ...

    journal_title:International journal of dermatology

    pub_type: 杂志文章


    authors: Aksoy B,Hapa A,Mutlu E

    更新日期:2018-02-01 00:00:00

  • Quality of life and related factors in a cohort of plaque-type psoriasis patients in La Coruña, Spain.

    abstract:BACKGROUND:Psoriasis can significantly affect the physical, psychological, and social aspects of a patient's life. Many studies have evaluated the effects of psoriasis on quality of life (QoL), but results in many cases are contradictory. OBJECTIVES:This study was conducted to assess the relationships between the char...

    journal_title:International journal of dermatology

    pub_type: 杂志文章


    authors: Fernández-Torres RM,Pita-Fernández S,Fonseca E

    更新日期:2014-11-01 00:00:00

  • Deep mycoses in Amazon region.

    abstract::Patients with deep mycoses diagnosed in dermatologic clinics of Manaus (state of Amazonas, Brazil) were studied from November 1973 to December 1983. They came from the Brazilian states of Amazonas, Pará, Acre, and Rondônia and the Federal Territory of Roraima. All of these regions, with the exception of Pará, are situ...

    journal_title:International journal of dermatology

    pub_type: 杂志文章


    authors: Talhari S,Cunha MG,Schettini AP,Talhari AC

    更新日期:1988-09-01 00:00:00

  • Trends in the epidemiology of cutaneous leishmaniasis in a young adult population in Israel: a long-term survey.

    abstract:BACKGROUND:The Israel Defense Forces (IDF) medical records offer a unique and valid 28-year view of the striking differences in cutaneous leishmaniasis (CL) seasonality patterns and incidence rates between the military and civilian sectors in Israel. AIM:To determine the annual epidemiology and seasonality trends of C...

    journal_title:International journal of dermatology

    pub_type: 杂志文章


    authors: Mimouni D,Balicer RD,Levine H,Klement E,Bar-Zeev Y,Davidovitch N,Zarka S

    更新日期:2009-06-01 00:00:00

  • Epidemiological and clinical patterns of genital lesions.

    abstract::A 5-year study of 668 patients with genital lesions revealed that teenagers and those in the age group of 20 to 40 are most vunerable. The poor, the uneducated and unmarried persons are at high risk. Chancroid and syphilis are the majority of cases. Inguinal bubo, herpes pregenitalis, condylomata acuminata, erosive ba...

    journal_title:International journal of dermatology

    pub_type: 杂志文章


    authors: Sehgal VN,Rege VL,Sehgal N,Kharangate VN,Mascarenhas MF

    更新日期:1976-10-01 00:00:00

  • Pheohyphomycosis caused by Exophiala spinifera: a rare occurrence.

    abstract::A 10-year-old immunocompetent boy presented with multiple, verrucous, disseminated pheohyphomycotic lesions caused by Exophiala spinifera. The patient was not responsive to combination antifungal therapy (itraconazole, terbinafine, fluconazole) and cryotherapy. As antifungal susceptibility is known to be variable for ...

    journal_title:International journal of dermatology

    pub_type: 杂志文章,评审


    authors: Singal A,Pandhi D,Bhattacharya SN,Das S,Aggarwal S,Mishra K

    更新日期:2008-01-01 00:00:00

  • Treatment of histoid leprosy: a lack of consensus.

    abstract::Histoid leprosy is a rare variant of leprosy with a unique clinical presentation and bacilli rich histology. These patients are large reservoirs for disease and vectors for spread, making prompt diagnosis and treatment crucial. To date, no consensus on treatment and duration exists. This paper aims to investigate the ...

    journal_title:International journal of dermatology

    pub_type: 杂志文章,评审


    authors: Bartos G,Sheuring R,Combs A,Rivlin D

    更新日期:2020-10-01 00:00:00

  • Use of colchicine in the treatment of Behçet's disease.

    abstract::To date, various treatment modalities have failed to produce consistent improvement in patients having Behçet's disease. Recent reports in the literature, however, have shown promising results with the use of colchicine. Our patient, an 18-year-old white woman, satisfied the 1977 Istanbul Conference criteria for Behçe...

    journal_title:International journal of dermatology

    pub_type: 杂志文章


    authors: Harper RM,Allen BS

    更新日期:1982-11-01 00:00:00

  • A multicenter epidemiological study of acne vulgaris in Korea.

    abstract:BACKGROUND:Acne is a common skin disorder that affects both adolescents and adults. However, few epidemiological studies on this condition have been conducted in Asia. OBJECTIVES:The purpose of this study was to analyze the incidence of acne and to identify its demographic and clinical features and aggravating factors...

    journal_title:International journal of dermatology

    pub_type: 杂志文章,多中心研究


    authors: Suh DH,Kim BY,Min SU,Lee DH,Yoon MY,Kim NI,Kye YC,Lee ES,Ro YS,Kim KJ

    更新日期:2011-06-01 00:00:00

  • Surgical pearl: a simple means of disarming the "locked and loaded" needle.

    abstract:BACKGROUND:Surgery, in any setting, has several inherent risks not only to the patient, but the physician and his assistants as well. Safe handling and management of the sharps to prevent inoculation injuries is one of these risks, in particular: 1) instrument hand-off of the needle and needle driver between the physic...

    journal_title:International journal of dermatology

    pub_type: 杂志文章


    authors: Kunishige J,Wanitphakdeedecha R,Nguyen TH,Chen TM

    更新日期:2008-08-01 00:00:00

  • Lupus erythematosus-like eruption due to D-penicillamine in progressive systemic sclerosis.

    abstract::A 58-year-old woman with progressive systemic sclerosis developed a butterfly erythematous eruption, hemorrhagic maculae, crusting, and erosions on the face 15 days following administration of D-penicillamine. This appeared to be a lupus erythematosus-like eruption due to an adverse drug reaction to D-penicillamine be...

    journal_title:International journal of dermatology

    pub_type: 杂志文章


    authors: Tsankov NK,Lazarova AZ,Vasileva SG,Obreshkova EV

    更新日期:1990-10-01 00:00:00