Abstract:
BACKGROUND:Ayurvedic medicines are known to contain arsenic and concentrations up to toxic levels have been reported in certain formulations. However, clinical disease due to arsenic containing ayurvedic medicines has rarely been reported. We seek to highlight the existence of toxic levels of arsenic in certain ayurvedic preparations that can produce serious systemic manifestations. METHODS:An 11-year-old girl developed manifestations of arsenical keratosis (punctuate palmoplantar keratoderma and leucomelanoderma) and non-cirrhotic portal hypertension, 6 months and 18 months respectively after intake of ayurvedic medications, prescribed for epilepsy. The eight ayurvedic preparations consumed by the patient and her serum levels were analyzed for arsenic content. RESULTS:Arsenic content of ayurvedic medicines ranged from 5 mg/L to 248 mg/L. The serum arsenic level was 202.20 microg/L (normal < 60 microg/L). Skin manifestations improved after the discontinuation of ayurvedic medications. CONCLUSIONS:Ayurvedic medications should be consumed under strict guidance and supervision of qualified practitioners to prevent such catastrophies.
journal_name
Int J Dermatoljournal_title
International journal of dermatologyauthors
Khandpur S,Malhotra AK,Bhatia V,Gupta S,Sharma VK,Mishra R,Arora NKdoi
10.1111/j.1365-4632.2008.03475.xsubject
Has Abstractpub_date
2008-06-01 00:00:00pages
618-21issue
6eissn
0011-9059issn
1365-4632pii
IJD3475journal_volume
47pub_type
杂志文章abstract::Chronic idiopathic urticaria (CIU), characterized by the appearance of itchy wheals of unknown etiology, can be extremely debilitating and can significantly reduce a patient's quality of life (QOL). Fexofenadine, a non-sedating, H1-receptor selective, long-acting antihistamine, is licensed worldwide for the treatment ...
journal_title:International journal of dermatology
pub_type: 杂志文章,评审
doi:10.1046/j.1365-4362.2002.01599.x
更新日期:2002-10-01 00:00:00
abstract:BACKGROUND:Keloids are benign dermal tumors characterized by fibroblastic proliferation and excessive accumulation of collagen. Oxymatrine (OMT) is an alkaloid extracted from the Chinese herb Sophora japonica with capacities of anti-fibrosis. OBJECTIVE:To evaluate the effects of OMT on collagen production and to explo...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4632.2011.05234.x
更新日期:2012-04-01 00:00:00
abstract:BACKGROUND:Millions of people are infested by head lice every year. However, louse transfer between hosts is not well-understood. Our goals were to determine: (1) which stages were most likely to disperse and why, (2) the likelihood of fomites transmission, and (3) if host blood gender affects louse development. METHO...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4632.2005.02418.x
更新日期:2005-10-01 00:00:00
abstract:BACKGROUND:Atopic dermatitis (AD) is a chronic, pruritic inflammatory skin disease. Angiopoietin is an intrinsic mediator induced by T helper 2 cytokines and has been reported it to play a critical role in the pathogenesis of AD. OBJECTIVES:To determine the relationship between circulating angiopoietin-2 (Ang-2) in AD...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/ijd.14620
更新日期:2019-11-04 00:00:00
abstract::Head louse infestations continue to be a concern of public health in most countries, including the most developed ones. The present recommendations are intended to inform and stress the role and impact of the different authorities, institutions, industry, and the public in the control of head lice in order to reduce t...
journal_title:International journal of dermatology
pub_type: 杂志文章,评审
doi:10.1111/ijd.15096
更新日期:2020-08-07 00:00:00
abstract::Telangiectasia macularis eruptiva perstans (TMEP) is a cutaneous form of mastocytosis. It has been rarely associated with an underlying myeloproliferative disorder. We report the case of a patient, while receiving treatment for thrombocytosis, with both platelet production and function inhibitors presented with TMEP. ...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4632.2004.02249.x
更新日期:2004-12-01 00:00:00
abstract:BACKGROUND:Matrine is a traditional Chinese medicine with significant inhibitory activity against malignant tumors. Its effects on the invasiveness and metastasis of malignant tumors have rarely been reported. AIM:To investigate whether matrine can inhibit the metastasis-related activities of the human malignant melan...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4632.2008.03627.x
更新日期:2008-05-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Recent studies have implicated the association between oxidative stress and inflammation in pathogenesis of psoriasis and its associated comorbidities. Hence, we undertook to study inflammatory markers such as sialic acids and the oxidative stress index (OSI) in patients with psoriasis vulgari...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/ijd.13196
更新日期:2016-08-01 00:00:00
abstract:BACKGROUND:There is a worrying lack of epidemiological data on the geographical distribution and burden of subcutaneous mycoses in Peru, hindering the implementation of surveillance and control programs. OBJECTIVES:This study aimed to estimate the disease burden of subcutaneous mycoses in Peru and identify which funga...
journal_title:International journal of dermatology
pub_type: 杂志文章,meta分析,评审
doi:10.1111/ijd.13665
更新日期:2017-10-01 00:00:00
abstract:BACKGROUND:Regulatory T cells (Tregs) play an important role in autoimmune diseases. In skin, the presence of Tregs is thought to be mandatory for suppression of autoreactive T cells. Here, we assess the number of Tregs in skin of healthy subjects and patients with an autoimmune dermatosis. METHODS:Immunohistochemical...
journal_title:International journal of dermatology
pub_type: 杂志文章
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更新日期:2014-03-01 00:00:00
abstract:BACKGROUND:The rate of human immunodeficiency virus (HIV) infection in women of reproductive age has increased dramatically in the last decade. The effects of pregnancy on the prevalence of cutaneous diseases in this group is unclear. OBJECTIVES:To compare the prevalence of cutaneous diseases in healthy pregnant women...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1046/j.1365-4362.2003.01776.x
更新日期:2003-07-01 00:00:00
abstract::Squamous cell carcinoma (scc) of the skin was studied in two similar populations, one living in the temperate zone of Australia, the other living in the tropics. In the tropics, the patients were significantly younger, the man to woman ratio approached unity, and women had significantly more sccs on the legs. In the t...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4362.1992.tb02697.x
更新日期:1992-07-01 00:00:00
abstract:BACKGROUND:Although disease severity, gender, body weight, and previous treatments have all been reported to affect clinical response of psoriasis vulgaris to narrowband ultraviolet B (NB-UVB) therapy, little information about possible local (lesional) influencing factors is available. OBJECTIVE:To assess correlations...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/ijd.13983
更新日期:2018-06-01 00:00:00
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journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/ijd.13340
更新日期:2016-11-01 00:00:00
abstract::Patients with deep mycoses diagnosed in dermatologic clinics of Manaus (state of Amazonas, Brazil) were studied from November 1973 to December 1983. They came from the Brazilian states of Amazonas, Pará, Acre, and Rondônia and the Federal Territory of Roraima. All of these regions, with the exception of Pará, are situ...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4362.1988.tb00925.x
更新日期:1988-09-01 00:00:00
abstract:BACKGROUND AND DESIGN:Scorpion stings are a serious problem in Khuzestan, a southwestern province of Iran. In around 5 years, 36,463 patients with scorpion stings have been seen. Most of the patients had no cutaneous findings, but a small group of patients developed various local and generalized skin manifestations. Pa...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1046/j.1365-4362.1998.00386.x
更新日期:1998-07-01 00:00:00
abstract::A 31-year-old man, an intravenous drug user and in an advanced stage of acquired immune deficiency syndrome (AIDS), was admitted in our Department for the treatment of skin lesions that had been diagnosed as molluscum contagiosum (MC). The clinical examination revealed the presence of multiple nodular lesions, some of...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4362.1996.tb01616.x
更新日期:1996-01-01 00:00:00
abstract::Five cases of chronic bullous dermatosis of childhood (CBDC), a rare bullous disease, are presented. Also known as linear IgA bullous dermatitis, it has significant immunofluorescence findings. Treatment with dapsone, 50 mg daily, is recommended. ...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4362.1986.tb03400.x
更新日期:1986-01-01 00:00:00
abstract:OBJECTIVE:The purpose of the study was to examine the eggs of pubic lice with consideration of their clinical relevance. STUDY DESIGN:Pubic lice eggs were examined by scanning electron microscopy (SEM). RESULTS:The egg is totally encased by a proteinaceous sheath, except for the operculum, by which oxygen exchange oc...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1046/j.1365-4362.2000.00901.x
更新日期:2000-03-01 00:00:00
abstract::Biopsy specimens of cutaneous discoid lesions of 71 patients with cutaneous lupus erythematosus (CLE) were studied. The material was examined by direct immunofluorescence (DIF) to establish positivity and morphologic patterns of immunoglobulins and complement deposits in the basement membrane zone (BMZ). A correlation...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4362.1992.tb03567.x
更新日期:1992-04-01 00:00:00
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journal_title:International journal of dermatology
pub_type: 临床试验,杂志文章
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更新日期:1994-08-01 00:00:00
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journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4632.2004.02340.x
更新日期:2006-01-01 00:00:00
abstract:BACKGROUND:Hidradenitis suppurativa (HS) is a chronic, inflammatory, and recurring disease mainly observed in adults. Obesity is considered an important independent factor in HS development and is associated with a higher prevalence of HS in children. We aimed to characterize the clinical presentation of HS in overweig...
journal_title:International journal of dermatology
pub_type: 杂志文章
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更新日期:2019-09-09 00:00:00
abstract:BACKGROUND:Mycetoma is a chronic suppurative and/or granulomatous inflammatory lesion of skin, subcutaneous tissue, fascia, and tendons caused by the traumatic inoculation of either fungal (eumycotic) or bacterial (actinomycotic) organisms present in the soil. The disease is characterized by triad of tumefaction, disch...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4632.2010.04610.x
更新日期:2010-11-01 00:00:00
abstract:BACKGROUND:Female pattern hair loss (FPHL) is a common disorder but presents severe psychosocial problems in many female patients. Adipose tissue-derived stem cells (ADSCs) and conditioned media of ADSCs (ADSC-CM) are reported to promote hair growth in vitro. However, there are no clinical reports on the treatment of a...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/ijd.12650
更新日期:2015-06-01 00:00:00
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journal_title:International journal of dermatology
pub_type: 临床试验,杂志文章
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更新日期:2004-04-01 00:00:00
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journal_title:International journal of dermatology
pub_type: 杂志文章
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更新日期:2010-06-01 00:00:00
abstract:BACKGROUND:Allergic contact dermatitis (ACD) is a manifestation of a cell-mediated immune response, but its mechanism remains unknown. Recently, we investigated whether ACD involves various neuropeptides. Substance P (SP) is a neuropeptide that is known to act as a neurokinin receptor when the immune response is initia...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4632.2011.05197.x
更新日期:2012-08-01 00:00:00
abstract::In a survey of clinical trials concerning the efficacy of short-contact therapy with anthralin in psoriasis vulgaris, focusing principally on methodologic issues, twenty-four papers published between January 1982 and December 1989, in English, French, and Italian, were selected. Nine of 24 papers reported on more than...
journal_title:International journal of dermatology
pub_type: 杂志文章,meta分析
doi:10.1111/j.1365-4362.1992.tb03254.x
更新日期:1992-02-01 00:00:00
abstract::Classical acupuncture focuses primarily on treating the person, and secondarily treating the illness. The "symptoms" are regarded as "branch" expressions of a "root" (constitutional) imbalance. Different root imbalances can produce the same symptoms. Five patients with eczema, for example, may reveal five distinct roo...
journal_title:International journal of dermatology
pub_type: 历史文章,杂志文章
doi:10.1111/j.1365-4632.2009.03899.x
更新日期:2009-06-01 00:00:00