Oxymatrine inhibits collagen synthesis in keloid fibroblasts via inhibition of transforming growth factor-β1/Smad signaling pathway.

abstract：BACKGROUND:Mucosa-associated epithelial chemokine (MEC; CCL28) is considered to be pivotal in mediating the migration of CC chemokine receptor 3- and 10- (CCR3- and CCR10)-expressing, skin-homing, memory, cutaneous lymphocyte-associated antigen-positive (CLA(+)) T cells. CCL28 is selectively and continuously expressed ...

journal_title：International journal of dermatology

authors： Ezzat MH,Sallam MA,Shaheen KY

更新日期：2009-08-01 00:00:00

abstract：:Sera from 25 patients with type 1 (Lepra), upgrading and downgrading, and type 2 (erythema nodosum leprosum [ENL]) reactions were assayed, during the reaction and after its clinical remission, for changes in levels of alpha-1-antitrypsin (A1A) and C-reactive protein (CRP). The results were compared with those from nor...

journal_title：International journal of dermatology

authors： Sehgal VN,Bhattacharya SN,Shah Y,Sharma VK,Gupta CK

更新日期：1992-09-01 00:00:00

abstract：BACKGROUND:This study reports the comorbidity of lifetime psychiatric disorders in children and adolescents with alopecia areata (AA) in a child and adolescent psychiatry clinical sample. METHODS:Fourteen patients with AA were interviewed using the Diagnostic and Statistical Manual of Mental Disorders-Fourth edition (...

journal_title：International journal of dermatology

authors： Ghanizadeh A

更新日期：2008-11-01 00:00:00

abstract：BACKGROUND:Psoriasis presents many management complexities. A cornerstone of therapy has been topical corticosteroids, although over the past 10 years there have been many additions to the medication armamentarium. Furthermore, various combination regimens and approaches have been advocated. OBJECTIVE:We sought to cha...

journal_title：International journal of dermatology

authors： Pearce DJ,Stealey KH,Balkrishnan R,Fleischer AB Jr,Feldman SR

更新日期：2006-04-01 00:00:00

abstract：BACKGROUND:The hair cycle is regulated by various molecules, among which FGF-5 has been shown to promote the transition from anagen to catagen. The FGFR-1, a trans-membrane receptor of FGF-5 with tyrosine kinase activity, is localized in the follicular papilla of hair follicles. OBJECTIVES:In order to apply the antise...

journal_title：International journal of dermatology

authors： Tsuboi R,Yamazaki M,Matsuda Y,Uchida K,Ueki R,Ogawa H

更新日期：2007-03-01 00:00:00

abstract：:A survey of 115 pemphigus patients who have been followed for 4-24 years was carried out in an attempt to analyze the possible factors influencing the course and prognosis of the disease. At the time of the study, 45 patients were in complete remission, 45 still had lesions, and 25 had died. In 12 cases, the death occ...

journal_title：International journal of dermatology

authors： Seidenbaum M,David M,Sandbank M

更新日期：1988-10-01 00:00:00

abstract：:Nevus lipomatosus cutaneus superficialis (Hoffman-Zurhelle) is a distinct clinical entity. A case is reported in which the lesions were large, appeared early in childhood and were linear in distribution along the natal cleft. ...

journal_title：International journal of dermatology

authors： Girglia HS,Bhattacharya SK

更新日期：1975-05-01 00:00:00

abstract：BACKGROUND:Although disease severity, gender, body weight, and previous treatments have all been reported to affect clinical response of psoriasis vulgaris to narrowband ultraviolet B (NB-UVB) therapy, little information about possible local (lesional) influencing factors is available. OBJECTIVE:To assess correlations...

journal_title：International journal of dermatology

authors： Errichetti E,Stinco G

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND:Associations between vitamin D deficiency and a broad variety of independent diseases, including several bone diseases, various types of cancer, autoimmune diseases, hypertension, and cardiovascular disease, have been suggested. It is therefore important to detect and treat vitamin D deficiency in high-risk ...

journal_title：International journal of dermatology

authors： Van der Walt JE,Sinclair W

更新日期：2016-09-01 00:00:00

abstract：BACKGROUND:Atrophic acne scars are a frequent problem after acne. Hitherto, mainly invasive treatment measures were possible. In a recent paper, we demonstrated the positive effects of iontophoresis with 0.025% tretinoin gel vs. estriol 0.03%. OBJECTIVE:In this further study, the recording of the clinical effects of i...

journal_title：International journal of dermatology

authors： Schmidt JB,Donath P,Hannes J,Perl S,Neumayer R,Reiner A

更新日期：1999-02-01 00:00:00

abstract：BACKGROUND:Pyoderma gangrenosum (PG)-like lesions can be associated with Wegener's granulomatosis (WG); in rare instances, they could be the presenting sign of WG. The purpose of this study was to elucidate the relationship between these two disorders. METHODS:The clinical and histologic data from a case of WG with pr...

journal_title：International journal of dermatology

authors： Micali G,Cook B,Ronan S,Yadgir J,Solomon LM

更新日期：1994-07-01 00:00:00

abstract：BACKGROUND:Hand dermatitis is an acute or chronic inflammation of the skin of the hands from a multifactorial cause which may be endogenous, exogenous, or a combination of both. With a wide range in severity and recurrent periods of flares, it has significant impact on the quality of life of its sufferers. A history of...

journal_title：International journal of dermatology

authors： Otrofanowei E,Ayanlowo OO,Akinkugbe A,Oresanya FA

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND:Linear focal elastosis is an uncommon disorder that clinically shows band-like stria and a histological focal increase in elastic fibers. The disorder preferentially affects men after the age of 60 years and occurs on the lower back. The pathogenesis of linear focal elastosis is still somewhat of an enigma. ...

journal_title：International journal of dermatology

authors： Inaloz HS,Kirtak N,Karakok M,Ozgoztasi O

更新日期：2003-07-01 00:00:00

abstract：:A 21-year-old student of sports science presented with a 12-month history of a painful nodule on the sole of her left foot, which severely constrained her sporting activities. She was otherwise well. On examination there was a bluish pink 7-mm nodule on the arch of her left foot (Fig. 1). It was firm, exquisitely tend...

journal_title：International journal of dermatology

authors： Ezughah FI,Orpin S,Colloby PS

更新日期：2004-03-01 00:00:00

abstract：BACKGROUND:Reed's nevi are distinguished from Sptiz tumors by their significant melanogenesis and growth pattern. They may be confused with melanoma on clinical and histologic grounds. CASE REPORT:An unusual case in which multiple agminated Reed's nevi mimicked acral lentiginous malignant melanoma in an African-Americ...

journal_title：International journal of dermatology

authors： Abramovits W,Gonzalez-Serva A

更新日期：1993-04-01 00:00:00

abstract：:Cutaneous calcium deposition can occur in long-term inflammation. The deposition of calcium in long-standing acne may produce either small pigmented nodules or no visible lesions. The former type is or no visible lesions. The former type is much less common, with the nodules containing particulate spheres of mineral w...

journal_title：International journal of dermatology

authors： Basler RS,Watters JH,Taylor WB

更新日期：1977-11-01 00:00:00

abstract：:Atypical presentations of cutaneous tuberculosis are not so uncommon and are frequently overlooked in clinical practice, leading to late diagnosis and increased morbidity. We report three cases of lupus vulgaris with atypical presentations. The cases mimicked other chronic skin lesions like actinomycosis, mycetoma, an...

journal_title：International journal of dermatology

authors： Saritha M,Parveen BA,Anandan V,Priyavathani MR,Tharini KG

更新日期：2009-02-01 00:00:00

abstract：:The antimicrobial activity of gentian violet and brilliant green was tested against various strains of potential skin pathogens, by means of agar diffusion assay. The activity of both compounds was affected by pH. Gentian violet was found to be more active than brilliant green at pH 7.4, particularly against Pseudomon...

journal_title：International journal of dermatology

authors： Bakker P,Van Doorne H,Gooskens V,Wieringa NF

更新日期：1992-03-01 00:00:00

abstract：:During a 10-year period (1976-1985), eight Chinese patients from a population of 2.5 million fulfilled the criteria for dermatitis herpetiformis and linear IgA bullous dermatosis (LABD). These rare diseases among Asians presented during the third decade of life with homogenous linear IgA deposits along the dermoepider...

journal_title：International journal of dermatology

authors： Ratnam KV

更新日期：1988-01-01 00:00:00

abstract：BACKGROUND:Psoriasis is a chronic debilitating disease affecting approximately one million Canadians. The objective of this study is to estimate the economic burden in $CDN (2008) of moderate to severe plaque psoriasis among Canadian adults. METHODS:Using a cross-sectional design, direct resource use, costs, lost prod...

journal_title：International journal of dermatology

authors： Levy AR,Davie AM,Brazier NC,Jivraj F,Albrecht LE,Gratton D,Lynde CW

更新日期：2012-12-01 00:00:00

abstract：:Immunodepressed patients in the intermediate phase of Chagas' disease may undergo reactivation of the disease together with atypical symptoms. The case of an immunodepressed kidney transplant patient with reactivation of Chagas' disease with skin symptoms is reported. A 65-year-old man presented with infiltrated eryth...

journal_title：International journal of dermatology

authors： Gallerano V,Consigli J,Pereyra S,Gómez Zanni S,Danielo C,Gallerano RH,Guidi A

更新日期：2007-06-01 00:00:00

abstract：:The epidemiology of scabies for the last twelve years has been studied in Turkey. Information was obtained from three regions (Istanbul, Ankara and Erzurum) having different climates. There has been an increase in scabies in the years following 1969 in Ankara and Erzurum and from 1967 on in Istanbul. It reached its ma...

journal_title：International journal of dermatology

authors： Tüzün Y,Kotoğyan A,Cenesizoğlu E,Baransü O,Ozarmağan G,Ural A,Cilara A,Gürler A,Tat AL

更新日期：1980-01-01 00:00:00

abstract：:Allergic reactions to insulin, although very common, are usually mild and self-limited. Many persistent effects can be corrected by simple means available to the discerning physician. In a few patients, however, they are severe and cause extreme morbidity or even mortality. These patients need to be recognized promptl...

journal_title：International journal of dermatology

authors： Jegasothy BV

更新日期：1980-04-01 00:00:00

abstract：:A 70-year-old man developed herpes zoster over the right L5-S2 region for 3 days and was admitted for acyclovir therapy. He had a medical history of rectal cancer status post-colostomy and end-stage renal disease undergoing thrice weekly hemodialysis. Without a prior loading dose, acyclovir 500 mg (7.7 mg/kg) daily wa...

journal_title：International journal of dermatology

authors： Yang HH,Hsiao YP,Shih HC,Yang JH

更新日期：2007-08-01 00:00:00

abstract：BACKGROUND:Intralesional bleomycin is effective for the treatment of various dermatologic conditions. However, the efficacy of intralesional bleomycin for the treatment of corns has not been established. METHODS:A total of 50 patients with plantar corns were recruited and equally divided between groups A and B. Groups...

journal_title：International journal of dermatology

authors： Lee WJ,Lee SM,Won CH,Chang SE,Lee MW,Choi JH,Moon KC

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND:Tick bites are dermatoses not commonly encountered in Korea. Recognizing their clinical signs as well as their histopathologic findings is important in making a diagnosis of tick-related dermatoses. The incidence and causative species are different depending on the geographic areas. The histopathologic findi...

journal_title：International journal of dermatology

authors： Cho BK,Kang H,Bang D,Kim SN,Hwang S,Song ES

更新日期：1994-08-01 00:00:00

abstract：BACKGROUND:Although the causes of striae distensae (SD) remain to be elucidated, the condition is known to relate to changes in the structures that provide the skin with its tensile strength and elasticity. OBJECTIVE:This study was conducted to evaluate whether premature birth is a risk factor for SD. METHODS:A total...

journal_title：International journal of dermatology

authors： Kelekci KH,Kelekci S,Destegul E,Aksoy A,Sut N,Yilmaz B

更新日期：2011-10-01 00:00:00

abstract：:Histoid leprosy is a rare variant of leprosy with a unique clinical presentation and bacilli rich histology. These patients are large reservoirs for disease and vectors for spread, making prompt diagnosis and treatment crucial. To date, no consensus on treatment and duration exists. This paper aims to investigate the ...

journal_title：International journal of dermatology

authors： Bartos G,Sheuring R,Combs A,Rivlin D

更新日期：2020-10-01 00:00:00

abstract：:Paracoccidioidomycosis is a highly prevalent systemic mycosis in Brazil. The primary cutaneous form is rare and occurs in the absence of pulmonary involvement. Lesions located in the distal regions of the lower limbs are not uncommon and particularly in the feet may go unnoticed or even be confused with infectious or ...

journal_title：International journal of dermatology

authors： Nakamura R,Valgas N,Bichara RM,Brazuna D,Leverone A

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Until now mortality trends of melanoma and nonmelanoma skin cancer (NMSC) in Germany have been studied only in West Germany. We were interested in comparing mortality trends of melanoma and NMSC in West and East Germany before and after the post-communist transition. By analyses of health care...

journal_title：International journal of dermatology

authors： Stang A,Lampert T,Uhlemann T,Trocchi P

更新日期：2009-04-01 00:00:00